ライフサイエンスコーパス: inbred mouse strain

1 bility in the genetically predisposed 129/Sv inbred mouse strain.

2 a consistent manner, equivalent to any other inbred mouse strain.

3 pe apolipoprotein(a) have been created in an inbred mouse strain.

4 +) T cells compared to a resistant classical inbred mouse strain.

5 translational studies utilize only a single inbred mouse strain.

6 issues, such as colon and lung, of different inbred mouse strains.

7 brain samples of a panel of BXD recombinant inbred mouse strains.

8 as not achieved in three (A/J, AKR/J, CBA/J) inbred mouse strains.

9 ted with resistance to Bacillus anthracis in inbred mouse strains.

10 n platelet integrin alpha2beta1 levels among inbred mouse strains.

11 ic basis for several trait differences among inbred mouse strains.

12 set collected from F2 intercross studies of inbred mouse strains.

13 ularization in the BXD series of recombinant inbred mouse strains.

14 ed for each marker and tested on a set of 48 inbred mouse strains.

15 ntitative phenotype that varies widely among inbred mouse strains.

16 th saccharin preference in a large number of inbred mouse strains.

17 ative gene expression data, which vary among inbred mouse strains.

18 P markers were designed and typed against 54 inbred mouse strains.

19 largely congruent with the known history of inbred mouse strains.

20 processing between these two closely related inbred mouse strains.

21 n APP YAC transgene was transferred to three inbred mouse strains.

22 e results would at least generalize to other inbred mouse strains.

23 regulatory variation in 69 genes across four inbred mouse strains.

24 ssed in eight brain regions obtained from 14 inbred mouse strains.

25 x cardiovascular traits in two commonly used inbred mouse strains.

26 characteristics can be very different among inbred mouse strains.

27 r3 alleles and Sac phenotypes in recombinant inbred mouse strains.

28 th with lifespan, even among closely related inbred mouse strains.

29 /6, BALB/c, RIII, AKR, DBA/2, I, A/J and C3H inbred mouse strains.

30 r in striatal regions in AXB/BXA recombinant inbred mouse strains.

31 of lung eosinophilia, we tested 15 different inbred mouse strains.

32 6J mice and in 11 of the AXB/BXA recombinant inbred mouse strains.

33 gh exploitation of genetic differences among inbred mouse strains.

34 efting in the AXB and BXA set of recombinant inbred mouse strains.

35 lytropic env genes present in the genomes of inbred mouse strains.

36 n treatment) is inherited in A/J and C3H/HeJ inbred mouse strains.

37 and neuropathology they produce in panels of inbred mouse strains.

38 recently, been limited to a small number of inbred mouse strains.

39 scle disease in CD-1 mice as well as several inbred mouse strains.

40 to induce immune responses in corresponding inbred mouse strains.

41 ally by C57BL/6 CTLs stimulated by different inbred mouse strains.

42 mponents in dendritic cells from recombinant inbred mouse strains.

43 GWAS) cannot be productively performed using inbred mouse strains.

44 g can distinguish hair shafts from different inbred mouse strains.

45 (healer of ear wounds) and SM/J (nonhealer) inbred mouse strains.

46 ic variation in hematopoietic function among inbred mouse strains.

47 of thirteen classical and four wild-derived inbred mouse strains.

48 ve mouse hot spot in F1 hybrids derived from inbred mouse strains.

49 d a wide range of pulmonary metastasis among inbred mouse strains.

50 bility phenotype of four previously untested inbred mouse strains.

51 lymorphic APOBEC3 alleles found in different inbred mouse strains.

52 induced CNV in the BXD series of recombinant inbred mouse strains.

53 -1-induced disease, we examined 14 different inbred mouse strains.

54 ction of previous wake duration varies among inbred mouse strains.

55 study compared fear extinction in a panel of inbred mouse strains.

56 ss between the Large (LG/J) and Small (SM/J) inbred mouse strains.

57 etory phenotypes varied considerably in four inbred mouse strains.

58 tly less hippocampal neurogenesis than other inbred mouse strains [1] and do not perform well in lear

59 We report that females of some substrains of inbred mouse strain 129 are resistant to systemic plague

60 In the present study, we tested 12 inbred mouse strains (129/J, A/J, AKR/J, BALB/cJ, C3H/He

61 is a major contributor to AHL in nine other inbred mouse strains-129P1/ReJ, A/J, BALB/cByJ, BUB/BnJ,

62 cortex, and olfactory bulb) of 10 different inbred mouse strains (129S1/SvImJ, A/J, AKR/J, BALB/cByJ

63 We describe the origins and relationships of inbred mouse strains, 90 years after the generation of t

64 strains (Lewis and Fischer 344) or a pair of inbred mouse strains (A/J and C57BL/6J); (2) which of th

65 hology associated with R. parkeri infection, inbred mouse strains (A/J, BALB/c, C3H/HeJ, and C3H/HeN)

66 we screened reciprocal backcrosses of three inbred mouse strains, A/J, NOD/LtJ and SKH2/J, with age-

67 erin 23 gene (Cdh23(c.753A)), common to many inbred mouse strains, accelerates age-related hearing lo

68 -sensitive C57BL/6J and the normotensive A/J inbred mouse strains after they were provided with water

69 When homozygous, the Mor1 allele from the inbred mouse strain AKR/J diminishes the severity of the

70 etabolomic analysis performed using multiple inbred mouse strains, along with knowledge-based filteri

71 Inbred mouse strains also have highly variable plasma VW

72 ucture of the Naip array among commonly used inbred mouse strains, although these gross structural di

73 mbers can be significantly different between inbred mouse strains, analogous to the haplotype differe

74 served in crosses between females of the DDK inbred mouse strain and many non-DDK males.

75 t derived from DBA/2J (D2) and C57BL/6J (B6) inbred mouse strains and (B6xD2)F2 hybrid mice derived f

76 ernative splice products is observed between inbred mouse strains and appears to correlate with an in

77 ere to quantify gravity receptor function in inbred mouse strains and compare vestibular and auditory

78 iting in RNA samples isolated from different inbred mouse strains and dissected brain regions, as wel

79 Polymorphisms among inbred mouse strains and feral species suggest that muta

80 We surveyed inbred mouse strains and found that for the majority tes

81 We surveyed 120 inbred mouse strains and found that the frequency of adu

82 Although blood neutrophil numbers in inbred mouse strains and individual human subjects are t

83 e EMPReSSslim pipeline which is performed on inbred mouse strains and knock-out lines arising from th

84 hese assays are ubiquitously performed using inbred mouse strains and mutations placed on inbred gene

85 ng inflammation and toxicity across multiple inbred mouse strains and to use genome-wide association

86 These peptides were expressed in diverse inbred mouse strains and were recognized preferentially

87 cal F1 hybrids (between the DDK and C57BL/6J inbred mouse strains) and C57BL/6J males at markers link

88 mice, that contain the nuclear DNA from one inbred mouse strain, and the mtDNA from a different inbr

89 cells was quantified in the C57BL/6J and A/J inbred mouse strains, and in 25 recombinant inbred strai

90 onsumption across a panel of BXD recombinant inbred mouse strains, and that share a genomic region th

91 kinetic differences, was seen with six other inbred mouse strains, and was not observed using carboxy

92 ly mirrored in a murine genetic model, where inbred mouse strains are differentially susceptible to H

93 a variety of species, macrophages from most inbred mouse strains are nonpermissive for intracellular

94 st several days of infection.IMPORTANCE Most inbred mouse strains are relatively resistant to orthopo

95 Most inbred mouse strains are resistant to infection by L. pn

96 bestos fibers are clearly reduced in the 129 inbred mouse strain as compared with typical fibrogenesi

97 These data reveal limitations to the use of inbred mouse strains as preclinical models at vaccine de

98 To identify variants between inbred mouse strains at a single nucleotide resolution,

99 re very long, in the size range reported for inbred mouse strains (averaging 46 kb per chromosome end

100 adenovirus vector to immunize 26 recombinant inbred mouse strains (AXB and BXA) derived from A/J and

101 8%) T lymphocytes differ significantly among inbred mouse strains: B220% is high in C57BL/6J (B6) and

102 ance to Coccidioides immitis infection among inbred mouse strains: B6 mice are susceptible, while DBA

103 Two inbred mouse strains, BALB/c and CBA/Ca, were infected w

104 Mndal is highly polymorphic among inbred mouse strains, because it is absent in 10 of 24 s

105 ced leakage as early as 15 to 25 min in some inbred mouse strains, but not in others, whereas PA or L

106 me and caspase-1 in macrophages from certain inbred mouse strains, but the mechanism by which this oc

107 , higher than values previously estimated in inbred mouse strains by a larger bore microneedle manome

108 ogen B. gibsoni, we infected the susceptible inbred mouse strains C.B-17.scid and DBA/2 with a clinic

109 Mice of the inbred mouse strain C3H/HeJ have been shown to be homozy

110 The inbred mouse strain C3H/HeJ is prone to absence seizures

111 In two inbred mouse strains, C3H/2Ibg (C3H) and DBA/2Ibg (DBA/2

112 The common inbred mouse strain C57BL/6J (B6) restricts L. pneumophi

113 The inbred mouse strain C57BL/6J is widely used in models of

114 s from a second-generation intercross of the inbred mouse strains C57BL/6 and FVB/N.

115 Inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H) dif

116 Inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H) exh

117 Using the inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H), wh

118 elated traits in a segregating cross between inbred mouse strains C57BL/6J (B6) and DBA/2J (DBA).

119 334 mice derived from an intercross between inbred mouse strains C57BL/6J and C3H/HeJ.

120 assessing 331 back-cross (N2) progeny of two inbred mouse strains, C57BL/6 and FVB/N, previously show

121 n lung tissue from two genetically divergent inbred mouse strains, C57BL/6J and CAST/EiJ, both in une

122 We applied these methods to two inbred mouse strains: C57BL/6J and DBA/2J.

123 with varying susceptibilities for different inbred mouse strains; C57BL/6N are highly susceptible wh

124 he heme biosynthetic pathway) activity among inbred mouse strains can be attributed to variation in t

125 recent whole-genome resequencing study of 15 inbred mouse strains captured a significant fraction of

126 and related traits in an intercross between inbred mouse strains CAST/Ei and C57BL/6J.

127 Interestingly, several inbred mouse strains commonly used in behavioral, anatom

128 Numerous inbred mouse strains comprise models for human diseases

129 Inbred mouse strains contain numerous endogenous proviru

130 e we report a dense set of genotypes from 94 inbred mouse strains containing 10.77 million genotypes

131 ose at The Jackson Laboratory in 1993 in the inbred mouse strain DBA/1LacJ.

132 The inbred mouse strains DBA/2J and C57BL/6J exhibit contras

133 loned and characterized the Lv locus from an inbred mouse strain (DBA/2J) that has three times the no

134 of mammary cancer, we identified previously inbred mouse strains (DBA/2J, NZB/B1NJ, and I/LnJ) that

135 Among inbred mouse strains, DBA/2 mice are unique because of t

136 of the plt locus, we find that commonly used inbred mouse strains demonstrate at least three differen

137 ysaccharide (LPS) responder and nonresponder inbred mouse strains demonstrated that a single genetic

138 CMV (MCMV) infection varies among different inbred mouse strains depending on NK cell effector funct

139 Inbred mouse strains differ in susceptibility to anti-GB

140 Inbred mouse strains differ in their ability to demonstr

141 M9-dependent histone modifications using two inbred mouse strains differing only in their PRDM9 zinc

142 Certain inbred mouse strains display progression to lymphoma dev

143 Inbred mouse strains display significant differences in

144 Inbred mouse strains display variable sensitivity to LeT

145 The collection of classical inbred mouse strains displays heritable variation in a l

146 isease, show remarkably wide variation among inbred mouse strains (eg, C57BL/6 and BALB/c), resulting

147 These data indicate that inbred mouse strains exhibit differences in receptor fun

148 Interestingly, inbred mouse strains exhibit dramatic differences in the

149 Inbred mouse strains exhibit significant differences in

150 Macrophages from different inbred mouse strains exhibit striking differences in the

151 Inbred mouse strains exhibit striking differences in the

152 Ac1-16 peptide-specific T helper cells from inbred mouse strains expressing identical k haplotype-de

153 ANCA NCGN severity was investigated using 13 inbred mouse strains, F1 and F2 hybrids, bone marrow chi

154 C57BL/6 is the most commonly used inbred mouse strain for biomedical research, but widespr

155 of the extinction-impaired 129S1/SvImJ (S1) inbred mouse strain for multiple behavioral, autonomic,

156 FVB/N is considered an ideal inbred mouse strain for transgenic mouse production beca

157 y metastasis that can be assayed in multiple inbred mouse strains for further use in identification o

158 Accordingly, we screened 38 inbred mouse strains for susceptibility to MPXV.

159 ested dendritic cells derived from different inbred mouse strains for their abilities to be infected

160 in a reference population of BXD recombinant inbred mouse strains for which extensive single-nucleoti

161 ses for these traits in a set of recombinant inbred mouse strains formed from the cross of LG/J with

162 Strain-dependent differences exist in four inbred mouse strains frequently used for genetic manipul

163 which next generation sequence data from 17 inbred mouse strains had been aligned, we identify and i

164 Marked genetic variance in inbred mouse strains has been observed for sucrose intak

165 High-density SNP screening of panels of inbred mouse strains has been proposed as a method to ac

166 Atherosclerosis in inbred mouse strains has been widely studied by using an

167 gate protective immune responses, the use of inbred mouse strains has proven invaluable.

168 phenotypes of the available BxD recombinant inbred mouse strains have been determined.

169 Although inbred mouse strains have been the premier model organis

170 Detailed studies of seven inbred mouse strains have now revealed three strains (C5

171 A catalog of the genetic variation among inbred mouse strains, however, is required to enable pow

172 We show that inbred mouse strains (i.e., C3H and C57) with varying al

173 Analysis of multiple inbred mouse strains identified 117 antigens recognized

174 Linkage analysis using inbred mouse strains identified a locus on chromosome 7

175 Genetic analyses of inbred mouse strains identified loci affecting different

176 Sequence analysis of 15 standard inbred mouse strains identifies six Mpdz haplotypes that

177 moter was cloned from both the C3H and DBA/2 inbred mouse strains in an attempt to identify polymorph

178 Previous data have shown differences among inbred mouse strains in sensory gating of auditory evoke

179 Wide differences among inbred mouse strains in susceptibility to develop compon

180 bolites in liver extracts obtained from four inbred mouse strains in the study of acetaminophen-induc

181 hat the pattern of angiogenic response among inbred mouse strains in this ex vivo assay differs from

182 al) seizures were determined in 16 different inbred mouse strains in two different laboratories.

183 One example is the NOD inbred mouse strain, in which MZ B cell expansion has be

184 tigen sensitization and challenge of the A/J inbred mouse strain induced AHR, eosinophilic airway inf

185 n silico whole-genome association mapping of inbred mouse strains involving hundreds of thousands of

186 The BALB/cJ inbred mouse strain is a useful model system for testing

187 The SWXL-4 recombinant inbred mouse strain is unusually sensitive to recurrent

188 Age-related hearing loss (AHL) in common inbred mouse strains is a genetically complex quantitati

189 sociation mapping in model organisms such as inbred mouse strains is a promising approach for the ide

190 ence in H. capsulatum susceptibility between inbred mouse strains is attributable to the genotype at

191 fine structure of sequence variation across inbred mouse strains is needed.

192 adiotherapy and from radiation studies using inbred mouse strains, it is hypothesized that individual

193 ypothesis, we examined GSK-3 activity in two inbred mouse strains known to be susceptible (C57BL/6J)

194 pond to the F1 plasmid, suggesting that some inbred mouse strains may exhibit exaggerated responses t

195 e of memory retention, and they suggest that inbred mouse strains may provide a diversity of phenotyp

196 perturbations on the gut microbiota of five inbred mouse strains, mice deficient for genes relevant

197 t peritoneal macrophages from a wild-derived inbred mouse strain, MOLF/Ei, are hyporesponsive to CpG

198 Inbred mouse strains MRL and LG share the ability to ful

199 QTL) analysis of an intercross involving the inbred mouse strains NZB/BlNJ and SM/J revealed QTL for

200 for further genetic analysis, we screened 17 inbred mouse strains of various Bcg and H-2 genotypes fo

201 erve as an immunodominant focus in different inbred mouse strains or are there structural constraints

202 Inbred mouse strains provide a relatively stable and res

203 Isogenic inbred mouse strains provide a valuable approach to eluc

204 Inbred mouse strains provide the foundation for mouse ge

205 Retroviral insertional mutagenesis in inbred mouse strains provides a powerful method for canc

206 etween the two healing phenotypes for common inbred mouse strains (r=0.92) and RI mouse lines (r=0.86

207 Differences in AHR affinity between inbred mouse strains reflect variations in CYP1 inducibi

208 cerevisiae induced an acute inflammation in inbred mouse strains resembling human Ps and PsA-like di

209 mesticus Sry alleles, onto the C57BL/6J (B6) inbred mouse strain results in abnormal testis developme

210 The inbred mouse strain RIII has long been known for sheddin

211 -susceptible BALB/c substrain, identified in inbred mouse strain screening.

212 NON/Lt and NZO/Hl are inbred mouse strains selected for IGT and polygenic obes

213 ALS/Lt and ALR/Lt are inbred mouse strains selected for susceptibility and res

214 teractions between iNKT-cells and DCs in two inbred mouse strains should raise a cautionary note abou

215 Inbred mouse strains show a wide range of noise sensitiv

216 Whereas most inbred mouse strains show an intermediate level of inter

217 1) backcrosses involving the DDK and C57BL/6 inbred mouse strains show transmission ratio distortion

218 susceptibilities to LT in the larger set of inbred mouse strains showed a lack of correlation betwee

219 Inbred mouse strains showed clear variability in their r

220 Data obtained with inbred mouse strains suggested an association between a

221 /2)F(1) x C57BL/6 mice and B x D recombinant inbred mouse strains suggested tentative associations of

222 Analysis of macrophages from recombinant inbred mouse strains support the model that macropinocyt

223 resistance to obesity, two obesity-resistant inbred mouse strains, SWR/J and A/J, were compared to 3

224 bdas > 10, purported linkage at 1q41-42, and inbred mouse strains that consistently develop lupus.

225 We have identified genetic differences in inbred mouse strains that determine whether their cultur

226 From comparative microRNA profiling between inbred mouse strains that display profound differences i

227 CTT-1 was expressed by independently derived inbred mouse strains that express H2b.

228 nes encoding these proteins are defective in inbred mouse strains that serve as models of Hermansky-P

229 In inbred mouse strains the rate of thymic involution and t

230 ntry of phenotypic information obtained from inbred mouse strains, the phenotypic and genotypic infor

231 In transferring this system to inbred mouse strains, the third bit of good fortune was

232 ough urinary Mup protein levels vary between inbred mouse strains, this difference is most pronounced

233 mouse strain, and the mtDNA from a different inbred mouse strain to examine the genome-wide nuclear D

234 The studies reported here screened 8 inbred mouse strains to determine whether genetic factor

235 a genetic correlation of the sensitivity of inbred mouse strains to different assays of nociception

236 Susceptibility of inbred mouse strains to EAE is in part determined by maj

237 transcription factors between crosses of two inbred mouse strains to elucidate the regulatory mechani

238 surgically induced hindlimb ischemia between inbred mouse strains to identify key microRNAs involved

239 The response of inbred mouse strains to infection with Leishmania major

240 MTX, we directly compared the responses of 4 inbred mouse strains to MTX in the air-pouch model of ac

241 Resistance or susceptibility of inbred mouse strains to the parasite Leishmania major co

242 The differing responses of inbred mouse strains to the same pathogen reflect variat

243 l processes relevant to behavior and because inbred mouse strains vary in their responses to tests of

244 basis for this susceptibility, a panel of 36 inbred mouse strains was used to model genetic diversity

245 Using publicly available data from inbred mouse strains, we conducted a genome-wide associa

246 nd nine of its metabolites in plasma from 13 inbred mouse strains, we correlated strain-specific diff

247 In the BXD series of recombinant inbred mouse strains, we have mapped the regions respons

248 study, structural changes in glomeruli of 24 inbred mouse strains were characterized in male mice at

249 To get around this problem, inbred mouse strains were developed, leading to identifi

250 Seven inbred mouse strains were immunized against human factor

251 ed to analyze the median survival data after inbred mouse strains were infected with C. albicans, whi

252 otransformation systems prepared from the 15 inbred mouse strains were measured.

253 Allelic gene differences exist among inbred mouse strains which control structure and tissue-

254 eron (IFN-gamma) and interleukin-4 (IL-4) in inbred mouse strains which differ in their susceptibilit

255 as well as the NMDA receptor-deficient 129S6 inbred mouse strain, which also lacks tolerance, exhibit

256 e studied the C3H/HeJ (C3H) and C57BL/6 (B6) inbred mouse strains, which differ in their susceptibili

257 and molecular traits in more than 100 unique inbred mouse strains, which were fed a diet rich in fat

258 Inbred mouse strains with age-related hearing loss (AHL)

259 Infection of inbred mouse strains with Borrelia burgdorferi results i

260 cells (ECs) were isolated from the aorta of inbred mouse strains with different susceptibilities to

261 immunoreactivity in the taste tissue of two inbred mouse strains with different Tas1r3 haplotypes an

262 ulin resistance, and glucose metabolism in 3 inbred mouse strains with differing susceptibilities to

263 as1r3 gene and its flanking regions from six inbred mouse strains with high and low saccharin prefere

264 Three inbred mouse strains with known secretory phospholipase

265 for 5 days (12-hour light/dark cycle) in two inbred mouse strains with low (A/J) and high (DBA/2J) hy

266 a combination of behavioural analysis of six inbred mouse strains with quantitative gene expression p

267 Comparing variability among inbred mouse strains with respect to a specific phenotyp

268 al lymphocytic activation molecule (Slam) in inbred mouse strains, with the Slam haplotype 1 expresse

269 Mvwf6-7) using a backcross approach with the inbred mouse strains WSB/EiJ and C57BL/6J.