ライフサイエンスコーパス: inbreeding depression

1 y observed association between herkogamy and inbreeding depression.

2 endosperm imprinting, hybrid phenotypes and inbreeding depression.

3 ly recessive deleterious alleles will reduce inbreeding depression.

4 The advantage is inversely related to local inbreeding depression.

5 es with long generation intervals and severe inbreeding depression.

6 tilization selection, and/or the severity of inbreeding depression.

7 ul tool to study the genetic architecture of inbreeding depression.

8 srupting self-incompatibility and leading to inbreeding depression.

9 while simultaneously estimating sex-specific inbreeding depression.

10 ns and may contribute substantially to total inbreeding depression.

11 d not appreciably diminish overall levels of inbreeding depression.

12 igh levels of selfing in plants despite high inbreeding depression.

13 or inviable, sl-CSD can generate substantial inbreeding depression.

14 of floral size expressed highly significant inbreeding depression.

15 lations have rendered the species at risk of inbreeding depression.

16 system itself in response to such factors as inbreeding depression.

17 he relationship between prior inbreeding and inbreeding depression.

18 ficient, revealing direct, but not indirect, inbreeding depression.

19 fects on viability, are contributing to this inbreeding depression.

20 to strong genetic drift and at high risk of inbreeding depression.

21 als dynamic genome evolution and hotspots of inbreeding depression.

22 aphroditic selfing rates and the strength of inbreeding depression.

23 ay express recessive genetic load and suffer inbreeding depression.

24 S-linked genetic load compared with overall inbreeding depression.

25 itland approach for field-based estimates of inbreeding depression.

26 s sizes, and to estimate the power to detect inbreeding depression.

27 which estimate of F is optimal for detecting inbreeding depression.

28 nservation and ecology, such as the study of inbreeding depression.

29 opulations may be subject to consequences of inbreeding depression.

30 alleles, supporting the dominance theory of inbreeding depression.

31 pulation numbers, and reverse indications of inbreeding depression.

32 nd elsewhere, and there was some evidence of inbreeding depression.

33 se data to determine the extent and cause of inbreeding depression across other plant genomes.

34 The extent to which inbreeding depression affects longevity and patterns of

35 Moreover, inbreeding depression alone does not generally account f

36 e detected: (i) variation in reproduction or inbreeding depression among life stages, years and mater

37 We observed a significant inbreeding depression and an increase of genetic varianc

38 on the relationship between the magnitude of inbreeding depression and environmental stress and calcu

39 find strong support for interactions between inbreeding depression and environmental variation compar

40 pports the dominance theory of heterosis and inbreeding depression and establishes the oyster as an a

41 Inbreeding depression and genetic load have been widely

42 We investigated inbreeding depression and genetic load in a small (N(e)

43 In fact, with strong inbreeding depression and high selfing rates, evolution

44 Here, we investigate sex determination, inbreeding depression and inbreeding avoidance in Neodip

45 Siring probability also showed inbreeding depression and increased with male age, while

46 Processes including inbreeding depression and its impact on allelic and phen

47 Inbreeding depression and lack of genetic diversity in i

48 Here we show low inbreeding depression and marker-based estimates of self

49 etic selection for the joint distribution of inbreeding depression and mating system across species.

50 tential to influence the coevolution between inbreeding depression and mating system.

51 rare plants with mixed-mating systems, where inbreeding depression and pollinator scarcity may both c

52 f these evolutionary factors on the level of inbreeding depression and provides an approach that coul

53 tically established, despite being linked to inbreeding depression and sexual selection.

54 species may be particularly at risk because inbreeding depression and stochastic fluctuations in mal

55 The causes of inbreeding depression and the converse phenomenon of het

56 anscription play a role in hybrid vigour and inbreeding depression, and also in the absence of parent

57 scue in facilitating adaptation and reducing inbreeding depression, and suggest that demographic resc

58 luding the rate of adaptation, the extent of inbreeding depression, and the load of deleterious mutat

59 the 119 populations although the severity of inbreeding depression appears to vary among taxa.

60 that the deleterious effects of inbreeding (inbreeding depression) are expected to be more pronounce

61 The magnitude of inbreeding depression as expressed in the field can be e

62 recessive alleles are the primary source of inbreeding depression, as does its late expression in bo

63 Inbreeding depression associated with CSD is therefore e

64 ergence at the range limit, suggesting local inbreeding depression at both range limit populations; h

65 ought to increase relative female fitness is inbreeding depression avoidance, the magnitude of which

66 Multiplicative inbreeding depression (based on seed germination, early

67 terious alleles can lead to large amounts of inbreeding depression because of their high equilibrium

68 We investigated evidence for inbreeding depression by environment interactions in nin

69 reting the genetic basis of the variation in inbreeding depression by: (1) predicting the variation i

70 depression." There is mounting evidence that inbreeding depression can be exacerbated by environmenta

71 The magnitude of inbreeding depression can influence many aspects of a po

72 dicts that, at equilibrium, the magnitude of inbreeding depression caused by recessive alleles should

73 such as variation in male mating ability and inbreeding depression could potentially lead to the long

74 The selfer population experienced much lower inbreeding depression (delta = 0.05 +/- 0.02 SE) than th

75 ditions, there was a large sex difference in inbreeding depression (delta) and the inbreeding load (L

76 The change in inbreeding depression due to purging averaged across the

77 In this way we introduce the concept of "inbreeding depression effect variance," a parameter more

78 levels of inbreeding and reduced fitness via inbreeding depression, even as the population remained d

79 d no significant effect on the expression of inbreeding depression for above-ground dry mass.

80 Inbreeding depression for both species was low for all l

81 ns and compared mean fitness, heterosis, and inbreeding depression for eight large and eight small po

82 Seminatural conditions did not increase inbreeding depression for females, probably because fema

83 ced differences emerging in simulations with inbreeding depression for fitness.

84 We found significant inbreeding depression for germination rate (delta=0.33),

85 ., 12,000-65,000) will be required to detect inbreeding depression for likely effect sizes, and so st

86 quency of these major mutations, most of the inbreeding depression for male fertility and cumulative

87 These results suggest that most of the inbreeding depression for male fertility in this populat

88 tilocus heterozygosity, detected evidence of inbreeding depression for morphological traits.

89 population indicate that there is tremendous inbreeding depression for nearly every fitness component

90 Meta-analyses show that inbreeding depression for neonatal survival was signific

91 Significant inbreeding depression for pollen fertility was found in

92 e-sterility alleles contribute to 31% of the inbreeding depression for the fraction of viable pollen

93 n of viable pollen grains, and to 26% of the inbreeding depression for total fitness.

94 etween the neutral and selected loci and the inbreeding depression from the selected locus, irrespect

95 s inherent disadvantage are the avoidance of inbreeding depression generated by selfing and the abili

96 cly available computer program titled 'IDG' (Inbreeding Depression Genetics) to execute these procedu

97 pression by: (1) predicting the variation in inbreeding depression given arbitrary initial genetic va

98 nant role of semilethal alleles in embryonic inbreeding depression has implications for the evolution

99 inance was responsible for the observed high inbreeding depression, heterozygote advantage could not

100 If we are to understand the evolution of inbreeding depression (i.e., purging), we need quantitat

101 contribute to variability in the strength of inbreeding depression (ID) observed across adverse envir

102 nbreeding measures commonly used to estimate inbreeding depression (ID).

103 erimental designs typically used to estimate inbreeding depression (ID).

104 The cost of inbreeding (inbreeding depression, ID) is an important variable in t

105 lower fertility; (ii) offspring suffer from inbreeding depression; (iii) parents have more grandchil

106 gest evidence to date of an HFC being due to inbreeding depression in a natural population lacking a

107 is to provide information on the genetics of inbreeding depression in a primarily outcrossing populat

108 Here we investigate inbreeding depression in a range of life history traits

109 amounts to an approximately 69% increase in inbreeding depression in a stressful vs a benign environ

110 resolve the long-standing paucity of data on inbreeding depression in adult traits and total fitness.

111 and suggest that, to date, the prevalence of inbreeding depression in adult traits may have been unde

112 We also confirm previous findings of inbreeding depression in birth weight and juvenile survi

113 y, which revealed similar starting levels of inbreeding depression in both breeding systems, but also

114 ing) influence the experimental evolution of inbreeding depression in Caenorhabditis elegans.

115 er, very little is known about the levels of inbreeding depression in dioecious species, obviously be

116 and comparatively complete pedigree detected inbreeding depression in juvenile survival, but not in a

117 The magnitude of inbreeding depression in L. jepsonii, although greater t

118 The models are most likely to detect inbreeding depression in large populations, that is, in

119 s for both the low mean and high variance in inbreeding depression in M. annua, and we discuss the im

120 There was no significant inbreeding depression in most traits due to one generati

121 to be ubiquitous among studies that examine inbreeding depression in multiple environments, and a pr

122 Data are presented on mating systems and inbreeding depression in multiple populations of two ann

123 tially recessive deleterious alleles causing inbreeding depression in natural plant populations.

124 , spatial genetic structure, and sporophytic inbreeding depression in natural populations of a dioico

125 eding provide a powerful tool for evaluating inbreeding depression in natural populations, and sugges

126 study were to: (1) quantify the strength of inbreeding depression in North-American populations of A

127 ous studies have suggested that early-acting inbreeding depression in plants is primarily due to leth

128 chromosomal regions have distinct effects on inbreeding depression in polyploids.

129 his hypothesis by comparing the magnitude of inbreeding depression in self-incompatible and self-comp

130 t tool for mitigating detrimental effects of inbreeding depression in small, inbred populations, but

131 ny genetic disorders in humans and producing inbreeding depression in the majority of sexually reprod

132 y play an important role as a buffer against inbreeding depression in the offspring by alleviating th

133 Inbreeding depression in the selfer population, which na

134 um effective population size to avoid severe inbreeding depression in the short term is of the order

135 Biologists now recognize inbreeding depression in the wild, a phenomenon that wil

136 the coexistence of moderate selfing and high inbreeding depression in this strongly protandrous Silen

137 For age-specific mortality, the severity of inbreeding depression increased over the life span.

138 Inbreeding depression increases under stress in 76% of c

139 Inbreeding depression is a key factor in the maintenance

140 If inbreeding depression is caused primarily by recessive m

141 itness component and that almost all of this inbreeding depression is due to mildly deleterious allel

142 Inbreeding depression is expected to play an important b

143 Determining the genetic basis of inbreeding depression is important for understanding the

144 Understanding the genetic architecture of inbreeding depression is important in the context of the

145 Inbreeding depression is important in the evolution of p

146 reveals the important difference between how inbreeding depression is measured experimentally and how

147 Experimental studies often find that inbreeding depression is more severe in harsh environmen

148 Inbreeding depression is most commonly expressed as comp

149 Inbreeding depression is of major concern for the conser

150 Inbreeding depression is one of the leading factors prev

151 ife history could mean that the magnitude of inbreeding depression is routinely underestimated.

152 th America except in southern Florida, where inbreeding depression led to reproductive failure [3-5].

153 for all life history stages, with cumulative inbreeding depression less than 0.23 in all populations.

154 llowing long-distance dispersal, declines in inbreeding depression may also be facilitated by genetic

155 Therefore, we identify two ways by which inbreeding depression may be underestimated in studies o

156 ation among individuals in the expression of inbreeding depression may reflect lineage-specific diffe

157 Detailed studies suggest that the level of inbreeding depression may vary between populations.

158 Taken together, these findings suggest that inbreeding depression negatively impacts the overall pat

159 ome size of Arabidopsis, and the equilibrium inbreeding depression observed in this highly selfing pl

160 Inbreeding depression occurs when inbred individuals exp

161 The low (<< 0.5) inbreeding depression of outcrossers suggests that the m

162 and short-term lowering of fitness owing to inbreeding depression, of which the latter appears the m

163 In contrast, there was significant inbreeding depression only in flower number within self-

164 In contrast, inbreeding depression primarily caused by many genes wit

165 and improvements in biomedical correlates of inbreeding depression, provide strong evidence that gene

166 Inbreeding depression refers to lower fitness among offs

167 We observed preliminary evidence for inbreeding depression related to stress caused by fungal

168 non-lethal mutations, reducing the amount of inbreeding depression relative to that expected without

169 t in captivity may decrease the intensity of inbreeding depression, relative to the stressful conditi

170 y enhancing genetic variability and reducing inbreeding depression, respectively.

171 effects could have several causes, including inbreeding depression, shared incompatibility alleles, o

172 cists have been interested in inbreeding and inbreeding depression since the time of Darwin.

173 These findings could explain why inbreeding depression so frequently arises via compromis

174 of closely related parents often suffer from inbreeding depression, sometimes resulting in a slower g

175 In line with the prediction of sporophytic inbreeding depression sporophyte size was significantly

176 Together, these results suggest that inbreeding depression stemming from CSD has shaped matin

177 nding inconvertible evidence of the cause of inbreeding depression still presents a difficult challen

178 However, few previous inbreeding depression studies have considered longevity

179 its retention is accompanied by substantial inbreeding depression, suggesting that it is caused by m

180 (ii) Polyploids exhibit less inbreeding depression than do their diploid parents and

181 ore relevant to selection and the purging of inbreeding depression than previous measures.

182 ctions with insects can increase or decrease inbreeding depression (the loss of fitness due to self-f

183 important consequences for phenomena such as inbreeding depression, the evolution of diploidy, and le

184 iation in natural populations, the nature of inbreeding depression, the evolution of sexual reproduct

185 eduction in fitness-related traits known as "inbreeding depression." There is mounting evidence that

186 lternatively, the partial dominance model of inbreeding depression typically applied to polyploids ma

187 ogeny; (iii) differing values of selfing and inbreeding depression using population means vs. matched

188 Statistical power to detect inbreeding depression using SNP data depends on the actu

189 70-85% using population means; in all cases, inbreeding depression values were high in early and late

190 Cumulative inbreeding depression was 76% for maternal families, and

191 h theoretical expectations, the magnitude of inbreeding depression was lower in L. bicolor, the more

192 large populations (mean = 7%, SE = 27); and inbreeding depression was lower, although not significan

193 rogeny were grown in a common greenhouse and inbreeding depression was measured in germination, survi

194 udy of Scots pine from Finland, the level of inbreeding depression was much lower in northern than in

195 Moreover, inbreeding depression was observed in eight of 11 offspr

196 -incompatibility or to extreme, early acting inbreeding depression, we performed three diallel crosse

197 tive ability of pollen, as well as levels of inbreeding depression, we predict that the early product

198 On average, significant levels of inbreeding depression were observed for median life span

199 as the potential to moderate the severity of inbreeding depression, which in turn may favor inbreedin

200 Inbreeding depression, which refers to reduced fitness a

201 of standing variation for fitness traits is inbreeding depression, with its converse of heterosis or

202 terious mutations, reducing mean fitness and inbreeding depression within populations and increasing