ライフサイエンスコーパス: include

1 ange, 142-16608; mean age, 53-79 years) were included.

2 ening or staging from 2010 through 2014 were included.

3 d controlled trials with 2,751 patients were included.

4 e date of their initial cholecystectomy were included.

5 January 1, 2006, to December 31, 2013, were included.

6 es with a median follow-up of 2.6 years were included.

7 ston Methodist Hospital, Houston, Texas, and included 10 patients who were scheduled for enucleation

8 loci associated at genome-wide significance, including 13 new associations with COPD.

9 Our study included 1418 children (693 girls and 725 boys) with a m

10 The outbreak excess cases (included 156 cases) affected all age groups regardless g

11 A separate longitudinal sample (cohort B) included 16 MDD patients who underwent MRI at baseline t

12 Two natural history cohorts were studied including 168 longitudinal samples belonging to 66 patie

13 1 different SERAC1 variants were identified, including 20 that have not been reported before.

14 =25 mm Hg) was present in 82 patients (51%), including 29 (18%) regarded as moderate-severe (mean pul

15 pitopes with murine C1-specific group A mAbs including 2A9.

16 SCORE2 enrolled 362 participants, including 305 with CRVO and 57 with HRVO.

17 med restricted to a group of responders that included 40% of the cohort.

18 Five eligible studies including 4360 patients with acute ICH were pooled in me

19 nts (women: 51.0%) from Northern Sweden were included (7121 deaths; mean follow-up: 13.7 y).

20 -enriched compared to those from IL5tg mice, including 800-fold higher levels of eotaxin-1.

21 The final analysis cohort included 88 eyes in 3 groups: monthly (n = 19), TREX (n

22 ls that have not been previously identified, including 9 low-frequency variants pointing to functiona

23 Differences from related projects include a much broader definition of markables, connecti

24 Secondary outcomes included a composite of mortality or other medical compl

25 r of fact that the human gut microbiome also includes a non-bacterial fraction represented by eukaryo

26 Notably, this includes a shift from a protein-coding ASCC3 mRNA to a s

27 Excellent electrical characteristics, including a high ON/OFF ratio and transconductance, sugg

28 original Abeta42 structural sub-populations, including a sevenfold enhancement of the beta-hairpin fo

29 ved to recognize a diverse array of targets, including a short peptide.

30 We reviewed 311 studies including a total of 87 240 adults, children, and parent

31 foliar N would be improved only modestly by including additional data on foliar P, but doing so may

32 Future prospective testing, including additional dimensions of quality of life, is i

33 linicians, and the target patient population includes adults with joint inflammation suspected to be

34 Cancer cells share several metabolic traits, including aerobic production of lactate from glucose (Wa

35 sured using several complementary techniques including aerosol mass spectrometry (AMS), high-resoluti

36 A number of factors, including age, sex, and genotype, may affect these metab

37 ocol for all patients who commenced drug and included all patients who received at least one dose of

38 e and The target audience for this guideline includes all clinicians, and the target patient populati

39 These findings were similar when including all 210 patients with site-reported paired FFR

40 ange of increasingly common human disorders, including Alzheimer and Parkinson diseases, type II diab

41 Tauopathies, including Alzheimer's disease (AD) and other neurodegene

42 The implicated agents included amoxicillin/clavulanate (n = 3), temozolomide (

43 ssions (baseline, real-rTMS, sham-rTMS), all including an N-back task (3 task loads: N1, N2, N3; cont

44 in traditionally treatment-resistant groups, including AN.

45 Correlative studies included analysis of in vivo FLT3 inhibition by plasma i

46 the difference (percent) in impacts between including and excluding adaptation, irrespective of clim

47 ne Set Enrichment Analysis revealed pathways including apoptosis, DNA repair and early estrogen respo

48 These adjacencies can be included as constraints in structure prediction techniqu

49 Most included assays, with the exception of the Manual Blue C

50 the common goals of cardiac imaging in CHD, including assessment of structural and residual heart di

51 ociated with deficits in cognitive function, including attention, working memory, and episodic memory

52 0 mAb for the treatment of B cell neoplasms, including B cell chronic lymphocytic leukemia (B-CLL).

53 ns with comprehensive diagnostic information including bacterial identity and antimicrobial susceptib

54 cipants according to their lifestyle factors including body mass index, healthy diet, sedentary lifes

55 rom March 1, 2016, to December 30, 2016, and included both eyes of 100 patients with glaucoma or ocul

56 g three orders of magnitude in seed size and including both dormant and nondormant seeds.

57 e genome-wide significant in a meta-analysis including both identification and 4 verification cohorts

58 e sites was also found in many tissue types, including brain tissue.

59 c signatures of cardiovascular disease risk (including branched-chain amino acids, select unsaturated

60 a member of the Tec kinase family that also includes Btk.

61 Protamines from eutherian mammals, including bulls and humans, also contain multiple cystei

62 creased number of abortive infection events, including bursting of ITs and a reduction in the number

63 Maternal complications included cardiogenic shock (24%), mechanical support (28

64 racterized by a range of anatomical defects, including cardiomegaly, hyperflexibility of the joints,

65 e effects of age and sex on gene expression, including CD8(+) T cells for age and CD4(+) T cells and

66 on ontology driven by experimental variables including cell lines to organize and describe the divers

67 logic process driven by genomic aberrations, including changes in nucleotide sequences.

68 Incident CVD included CHD, stroke, heart failure, and peripheral arte

69 merging applications in the biomedical field including chemical sensing, biological imaging, drug del

70 We included children continuously enrolled within a month o

71 We included children from the Dutch National Network for Pe

72 e pathogenesis of inflammatory skin diseases including chronic urticaria which is associated by incre

73 rojection) to two non-constrained approaches including CIBERSORT and a method based on robust partial

74 of other well-known drivers of productivity, including climate and nutrient availability.

75 Secondary end points included clinical outcomes (major adverse cardiac events

76 uire input from a broad set of stakeholders, including clinicians and researchers from across multipl

77 immune-related genetic risk factors for AD, including coding variants in the gene TREM2 (triggering

78 eral neurological and psychiatric disorders, including cognitive decline associated with Alzheimer's

79 f psychological and physiological variables, including cognitive effort, arousal, attention, and even

80 This includes communication between organelles, which allows

81 major reprogramming of gene expression that includes components of the virulence-critical ESX-1 secr

82 Disease progression includes composite mortality, hospitalization, and 10% F

83 coatings through seven product applications, including construction and building, household and furni

84 The most commonly performed interventions included continuous passive motion, preoperative exercis

85 integumentary structures as organic layers, including continuous fields of epidermal scales and inta

86 licated in virulence at the mucosal surface, including contributions to colonization and immunopathog

87 ies to tailor them for specific applications include controlling their crystal size and shape.

88 Pals1 interacting proteins, including Crb3 and Wwtr1/Taz, have been linked to renal

89 Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (U

90 Most terrestrial plants, including crops, engage in beneficial interactions with

91 ons were also found in rarely reported genes including CRYBA4, CRYBA2, BFSP1, VIM, HSF4, and EZR.

92 Outcomes included cumulative CVD (coronary heart disease and stro

93 the pathology of many respiratory diseases, including cystic fibrosis.

94 elopment of improved or novel new compounds, including D1 agonists with better pharmacokinetics, func

95 Favorable cardiac remodeling at 6 months included decreases in end-diastolic (161 +/- 36 ml to 12

96 KO) male mice exhibit cognitive alterations, including defects in a novel object recognition task.

97 Clinical predictors included demographics, anthropometrics, cardiac and bloo

98 e included in our study, only eight of which included detection of hepatitis D virus RNA among anti-h

99 Secondary objectives include determining the incidence rate, relative risk (R

100 Urinary arsenosugars and their metabolites (including dimethyl arsenate (DMA), thio-dimethylarsinoyl

101 Statistical methods included discrete-time survival analyses.

102 Secondary end points included disease-free survival and the cumulative rate o

103 asses along with clinical correlation, which includes early involvement of ACTH and TSH and a relativ

104 es in enzymes involved in primary metabolism including energy transduction and deoxynucleotide produc

105 C through Twist-mediated oncogenic functions including epithelial-mesenchymal transition (EMT) and ca

106 to other PKD-associated signaling pathways, including ERK, mTOR, and Akt signaling, via PTPN13-media

107 age BC receiving an AI; secondary objectives included evaluation of adverse events, changes in sexual

108 These include excitatory populations that transmit information

109 te is effective for a variety of data types, including exome sequencing, whole-genome sequencing, RNA

110 at are potentially associated with the host, including extracellular magnesium limitation, low pH, an

111 These mutations included five de novo heterozygous loss of function muta

112 gile X family of RNA-binding proteins, which includes FMRP and FXR2P.

113 , generating B cells with up-regulated Nod1, including follicular and marginal zone B cells with natu

114 ssion controls brain activity and behaviors, including food intake.

115 icides in five of the six countries studied, including four studies using optimum analytical methods,

116 the Rag GTPases in response to amino acids, including GATOR1, a GTPase activating protein for RAGA,

117 in clinically relevant cognitive functions, including general intelligence, executive function, proc

118 ith astrocytic and oligodendroglial gliomas, including glioblastomas.

119 nown to predict and drive allograft fibrosis include graft quality, inflammation (whether "nonspecifi

120 We suggest a mainstreaming approach including greater integration of fungal diseases into ex

121 Many receptor systems, notably including growth factor receptors and G protein-coupled

122 After a meta-analysis including >300,000 European samples, we identified an ad

123 t role in many pathophysiological processes, including gut mucosal adaptation.

124 sine kinase is expressed in many cell types, including hematopoietic cells, and is a member of the Te

125 fective in the treatment of various ailments including hepatitis.

126 Highlighted topics include how solution-processing techniques can control t

127 ted through the multiple structural analyses including HPLC, IR and NMR.

128 chemotaxis assays on purified immune subsets including human pan-T cells, CD4(+) T cells, CD8(+) T ce

129 ive-sense single-stranded RNA (+RNA) viruses including human pathogens hepatitis C virus (HCV), Sever

130 nors that directly deliver a single species, including hydrogen sulfide, perthiol, and COS, and will

131 Wake-promoting cell types include hypocretin and GABA (gamma-aminobutyric-acid)-re

132 Optic nerve findings included hypoplasia with the double-ring sign, pallor, a

133 an adjuvant-free mix of three peptides that include immunodominant epitopes for gluten-specific CD4-

134 , and active section with phase shifters-are included in a single metal layer.

135 From a group of 79 patients included in a trial evaluating the role of pretreatment

136 gap with and without out-of-pocket spending included in household total consumption.

137 74 studies identified by our search, 30 were included in our study, only eight of which included dete

138 n (SD) age at diagnosis for the 65 057 women included in the analysis was 48.5 (11.1) years.

139 363 dental implants in 262 participants were included in the analysis.

140 tory Project of the Dystonia Coalition, were included in the analysis.

141 AH should be included in the differential diagnosis of solid-cystic p

142 323 to doxorubicin alone), all of whom were included in the intention-to-treat analysis.

143 tudy drug during the maintenance period were included in the primary efficacy and safety analyses.

144 All individuals included in the study were reviewed for sociodemographic

145 was 4.6 (0.40) years for the 61359 children included in the study.

146 f age and duration of less than 4 years were included in this study.

147 Hershey Medical Center, 95 patients were included in this systematic review.

148 g development and revealed several insights, including in sphingolipid-mediated apoptosis, inflammati

149 in children across the Asia-Pacific region, including in Vietnam, which has experienced a high burde

150 nd which nighttime signaling events revolve, including inactivation of KaiA and reciprocal regulation

151 common and is associated with poor outcomes, including increased mortality, among critically ill chil

152 ne cell subsets that occur following trauma, including induction of Th17-type CD4 T cells, reduced T-

153 Secondary outcomes included inflammatory markers.

154 contribute to modulation of host responses, including inhibition of type I interferon responses, sup

155 way mediates signals from multiple receptors including insulin receptors, pathogen-associated molecul

156 Similarly, including intraoperative features (AUC = 0.82; 95% CI: 0

157 Multiple RPE fates in AMD, including intraretinal cells that are highly prognostic

158 ing features of tuberculous spondylodiscitis included: involvement of the thoracic spine, involvement

159 selectivity of this assay were investigated, including ionic strength, AgNP concentration, PNA concen

160 inate the architecture of the amyloid state, including its stability and its capacity for formation o

161 tical signaling cascades downstream of LRP6, including JNK and WNT/beta-catenin, inhibited the biolog

162 There were 13 trials (n = 9850) that included kidney transplant recipients (6 trials), patien

163 ere dysregulation of sleep-wake homeostasis, including lack of recovery sleep and impaired behavioral

164 Strengths include large sample size, prospective design, and virtu

165 es decorated with several autophagy markers, including LC3 (microtubule-associated protein 1 light ch

166 ts remain undefined, but postulated pathways include loss of neuronal progenitor cells, damage to the

167 possessed stress tolerance characteristics, including lower malondialdehyde (MDA) content, lower wat

168 filling high-intensity statin prescriptions included male sex, filling beta-blocker and antiplatelet

169 Results NHL subtypes included mantle cell lymphoma (MCL; n = 28), follicular

170 ive compounds from their secretory granules, including mast cell-restricted proteases such as tryptas

171 Key eligibility criteria included measurable disease, failure of standard therapy

172 associated with a variety of human diseases, including metabolic disorders and cancer.

173 e-associated proteins (RAPs) from categories including metabolism and cell cycle, as well as RNA- and

174 These reactive intermediates, including metal-superoxo, -(hydro)peroxo, and high-valen

175 rium to utilize a variety of carbon sources, including microbiota-derived succinate.

176 miRs) to the miRISC in response to IL-1beta, including miR-146a-5p, miR-155-5p and miR-27b-3p.

177 separation of interphase and mitotic cells, including mitotic subphases, can be combined with proteo

178 predictors of mortality following recurrence included model for end-stage liver disease at LT >23, ti

179 xity of ERCP have been presented, but do not include modern endoscopic treatment modalities.

180 ded at baseline and 3, 6, and 9 months; they included modified sulcus bleeding index (mSBI), plaque i

181 d using the National Cancer Data Base, which includes more than 70% of patients newly diagnosed as ha

182 sion ameliorated multiple RTT-like features, including motor dysfunction and breathing irregularities

183 nesis -related gene expression pattern which includes myogenin and Myf5 up-regulation and Cyclin D1 d

184 GBCAs have a small risk of adverse effects, including nephrogenic systemic fibrosis (NSF), the untre

185 sis of apelin-derived peptides by proteases, including neprilysin (NEP).

186 ently known mechanisms for active forgetting include neurogenesis-based forgetting, interference-base

187 w span a range of methodological techniques, including neuroimaging, psychophysics, and traditional b

188 ) regulates various physiological processes, including neuronal activity, vascular tone, inflammation

189 mours of Haematopoietic and Lymphoid Tissues includes new criteria for the diagnosis of these disorde

190 tions have revealed several emerging issues, including new populations at risk because of travel or r

191 mposed of four modules that encode 80 genes, including novel and known virulence factors associated w

192 t public health burden in the United States, including obesity, hypertension, type 2 diabetes mellitu

193 ightly linked to severe metabolic disorders, including obesity, metabolic syndrome, lipodystrophy, an

194 , G, H, J, and K and unclassified fragments, including one subtype CRF25 isolate, which branched basa

195 orty-four retail milk samples were analyzed, including organic milk (n=10), conventional milk (n=14)

196 te additional regulators of gene expression, including other AP2 transcription factors, histone-modif

197 s to limit the emergence and spread of MDROs include oversight to decrease selective pressure for MDR

198 ntum; however, its impact on major outcomes, including pancreatic fistula, has yet to be adequately c

199 vity models either ignore inhibition or only include PAR inhibition.

200 Purposeful sampling was used to include patients of different gender, age, wound duratio

201 ized, double-blind, placebo-controlled trial included patients with schizophrenia, schizoaffective di

202 Secondary objectives included patients' assessment of their gastrointestinal

203 or patients with other clinical indications, including patients with diabetes mellitus and prediabete

204 ))-H activation via various redox manifolds, including Pd(0)/Pd(II), Pd(II)/Pd(IV), and Pd(II)/Pd(0).

205 t T0, the frequencies of CD4 T cell subsets, including peripheral T follicular helper (pTfh) cells, w

206 Health to support strategies and resources, including personnel, for increasing vaccination coverage

207 a complex mixture of chemical contaminants, including pharmaceuticals, present in discharges of wast

208 involved in cell turnover become uncoupled, including pharmacological treatments and disease models.

209 alcin, and Cyclin-D1 and of K-Ras effectors, including phosphorylated extracellular signal-regulated

210 complex traits, demonstrate the advantage of including population-specific sequences in imputation pa

211 isms mediating tumor viability and invasion, including potassium channel function and EPH receptor si

212 We present a model for RecN function that includes presynaptic stimulation of the bacterial repair

213 ith magnetic resonance imaging-confirmed NHS including primary and secondary intracerebral hemorrhage

214 standard tool for periodontal examinations, including probing depth measurements, but is limited by

215 an open approach or a laparoscopic approach (including procedures converted to open).

216 Main outcome measures include proportion of eye care providers who assess pati

217 leased by many eukaryotic cells; their cargo includes proteins, mRNA and microRNA (miR) that can be t

218 differential functional associations: these include PTEN, FUBP1, and CDH1.

219 ated with simeprevir or paritaprevir failure include R155K and D168E/V.

220 elated proteins expressed in Purkinje cells, including Rgs8, Pcp2, Pcp4, Homer3, Cep76 and Fam107b.

221 Crops particularly affected include rice and wheat, which are primary sources of die

222 in the effector portion of the RdDM pathway, including RNA POLYMERASE V (POL V), DOMAINS REARRANGED M

223 In some orthoretroviruses, including Rous Sarcoma Virus (RSV), CA carries a short a

224 es' roles in nurse-led chemotherapy clinics, including semi-structured interviews with nurses.

225 ase data is hampered by numerous challenges, including short-term surveillance that focuses on single

226 ral approaches to interpret the phase images including signal intensity histograms and texture analys

227 Markers on one chromosome were included simultaneously in a multilocus model and least

228 crimination and indicates that 113 variables including size, electronegativity, number of valence ele

229 ) undergo changes in function and structure, including skewing to myeloid lineages, lower reconstitut

230 e platforms suffer from serious limitations, including small sample sizes.

231 Land-cover change from energy development, including solar energy, presents trade-offs for land use

232 any different monospecies biofilms in vitro, including some of those produced by oral bacteria.

233 reases expression of EC morphogenesis genes, including Sox17, shifts the genomic targeting of Fli1 to

234 ied using biochemical and genetic approaches including specific knockdowns of genes of interest from

235 xpression of several tumor suppressor genes, including Src homology region 2 domain-containing phosph

236 : 1 day without implementing TSMB, the other including standardized (1.5 to 2 minutes) guided TSMB at

237 rors and other technology specific artifacts including strand bias and low base quality at read ends.

238 ted in a variety of adverse health outcomes, including substance use disorders.

239 complex recombinants of 2 or more subtypes, including subtypes A1, F, G, H, J, and K and unclassifie

240 lity to other immunopathological phenotypes, including survival after infection with coxsackievirus B

241 e ictal characteristics of these rat models, including SWDs and associated immobility, are also preva

242 Outcomes included symptoms, health status, and AF treatment, as w

243 advanced in situ characterisation techniques including synchrotron-based grazing incident X-ray diffr

244 PRs and further classified them into groups, including tandem repeats and Staphylococcus aureus repea

245 Participants included term neonates with magnetic resonance imaging-c

246 ifferentiate into multiple effector subsets, including ThCTL that mediate MHC class II-restricted cyt

247 chitecture of the immune system is likely to include the added dimensions of modulation by miRNAs and

248 Limitations of the study include the exclusivity of study sites to India, lack of

249 Limitations of this study include the lack of identification of optimal risk thres

250 The cost for the cohort, which included the cost of the test, subsequent treatments rec

251 The study included the data of 2233 subjects who experienced eithe

252 oped a multiscale model of fibrinolysis that includes the main chemical reactions: the microscale mod

253 ich is comparable to recent acute epidemics, including the 2014 Ebola and 2015 Zika epidemics.

254 y and cohesion of many biological molecules, including the adhesion proteins of several marine organi

255 is required for normal nematode development, including the all-important infectious stage.

256 erstanding the regulatory functions of RBPs, including the binding effects of the RNA helicase MOV10

257 Xpp1 are found among a broad range of fungi, including the biocontrol agent Trichoderma atroviride, t

258 cuss key experimental design considerations, including the choice of the method used to determine met

259 count for much of the variation in crowding, including the correlation between crowding and saccades.

260 gh mitosis and meiosis share many processes, including the DNA replication, chromosome condensation a

261 was subserved by a common network of areas, including the dorsomedial and dorsolateral prefrontal co

262 y GPCRs, but also receptor tyrosine kinases, including the highly cancer relevant insulin-like growth

263 ential critical roles in protein activation, including the histone acetyltransferase p300 acetylated

264 We identify five factors, including the HIV co-receptors CD4 and CCR5, that are re

265 A variety of examples are presented, including the identification of designer drugs and chemi

266 controls virtually all biological processes including the interactions between cells and biointerfac

267 ified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necros

268 actions within primary and metastatic sites, including the lung.

269 se a range of different molecular strategies including the mimicry of prosurvival Bcl-2 proteins.

270 views and discusses the scientific evidence, including the most recent studies, on the effects of die

271 t variations in cuticular drusen phenotypes, including the occurrence of retinal pigment epithelium (

272 his study, 16 drug biomarkers were selected, including the parent forms and the major human metabolit

273 A three-way comparison including the published short-read assembly (SR) constru

274 d with elevated perfusion in several regions including the right dorsal anterior cingulate cortex (AC

275 ecture and special physicochemical features, including the sheet-on-sheet sandwich-like structure, ul

276 fossilizable aspects of bone microstructure, including the sizes of vascular and lacunar (cellular) s

277 ised the full extracellular portion of CD23, including the stalk and head domain; 1 variant was ident

278 us invasive forest pest in several countries including the United States, Canada, and Europe.

279 An optimal sample preparation method, including the use of methanol at a 3:1 ratio of solvent

280 how macroscopic features of branched organs, including their size, network topology, and spatial patt

281 tions in cancer and inflammation management, including therapeutics, imaging and theranostics.

282 PD and have important clinical consequences, including therapeutics.

283 ce of a three-dimensional (3D) culture model including these cell types for investigating brain funct

284 ated archaea that, as well as Lokiarchaeota, includes Thor-, Odin- and Heimdallarchaeota.

285 The population at risk for HBV reactivation includes those who either currently are infected with HB

286 further uncover that several P2X receptors, including those able to desensitize, are permeable not o

287 241]; 95% confidence interval: -15.1, 60.0), including those from subanalyses.

288 quently occurring for hospitalized patients, including those receiving care in specialist palliative

289 Physicians (ACP) is attentive to all voices, including those who speak of the desire to control when

290 tment plants (MWWTPs) (Waterloo, Kitchener), including three upstream reference sites.

291 us viral replication in fibrocytes (possibly including tissue macrophages) and T and B lymphocytes in

292 d States, with limited further transmission, including to healthcare workers.

293 We conducted a fixed-effects meta-analysis, including, to our knowledge, the first analysis of the X

294 otential in autism spectrum disorders (ASD), including tuberous sclerosis complex (TSC).

295 ealth and Demographic Surveillance System to include two doses of HRV with the standard infant vaccin

296 due to different methodological approaches, including use of either peptide:N-glycosidases F and A (

297 s cells against various toxins and pathogens including viruses, intracellular bacteria and parasite.

298 ny possibilities to improve drug treatments, including with regard to drug pharmacology.

299 the Swedish Catheter Ablation Register were included, with information about exposure to warfarin in

300 that have displayed robust repair capacity, including Xenopus oocytes, Chlamydomonas, and Stentor co