ライフサイエンスコーパス: increasingly

1 rather than compounds, and scaffold queries increasingly abstract from chemical structures.

2 hallenge has grown as cancer datasets become increasingly abundant, making them cumbersome to store a

3 Active surveillance (AS) is increasingly accepted for managing low-risk prostate can

4 Cannabis use has become increasingly accepted socially and legally, for both rec

5 However, it is becoming increasingly accepted that the hepatic ECM proteome (i.e

6 ing engulfment of large particles and become increasingly acidic and proteolytic, ultimately fusing w

7 ue and quality of surgical care and has been increasingly adopted for a broad range of complex surgic

8 International air travel is increasingly affecting the epidemiology of infectious di

9 community data, the sessile community became increasingly algal dominated.

10 hosis and hepatocellular carcinoma (HCC) and increasingly an indicator for liver transplantation.

11 Bacterial pathogens are increasingly antibiotic resistant, and development of cl

12 cond, facilitated by new technologies, it is increasingly apparent that the bipolar phenotype is more

13 ticality assessment is a screening framework increasingly applied to identify materials of importance

14 origin and dispersal research and should be increasingly applied to these issues.

15 In addition, glia are now increasingly appreciated as active regulators of numerou

16 It is increasingly appreciated that the GABAB receptor forms p

17 Purpose Gene-expression profiles increasingly are used in addition to conventional progno

18 racterized by progressive cognitive decline, increasingly attributed to neuronal dysfunction induced

19 smitted infection testing (e-STI testing) is increasingly available as an alternative to testing in c

20 ral and tricuspid valve disease are becoming increasingly available because of the growing number of

21 s and utilizing ranked or weighted sequences increasingly available from high-throughput assays.

22 genome-wide TF ORFeome clone collections are increasingly available, screening protocols have limitat

23 la et sanitate suggests that well-being will increasingly be based on health, continued mental stimul

24 Neuroendocrine prostate cancer (NEPC) has increasingly become a clinical challenge.

25 ning immunotherapy with targeted therapy has increasingly become an appealing therapeutic paradigm fo

26 Endoscopic procedures have increasingly been used in the treatment of premalignant

27 TMCFs are increasingly being affected by fire, and the long-term e

28 es developed in the social sciences that are increasingly being applied to animal networks, of which

29 Woodchip bioreactors (WBRs) are increasingly being applied to remove nitrate from runoff

30 Lipid metabolism is increasingly being appreciated to affect immunoregulatio

31 oxidation of indigenous Cr(III) minerals is increasingly being recognized as a threat to groundwater

32 Fungi are increasingly being recognized as common members of the m

33 [4 + 2]-Cycloadditions are increasingly being recognized in the biosynthetic pathwa

34 Hepatitis E virus (HEV) infection is increasingly being reported in immunocompromised patient

35 Biological systems are increasingly being studied by high throughput profiling

36 ike peptide 1 receptor (GLP-1R) agonists are increasingly being used as treatment for type 2 diabetes

37 m cell-derived cardiomyocytes (hiPSC-CM) are increasingly being used for modeling heart disease and a

38 ts by RANO have been widely accepted and are increasingly being used in neuro-oncology trials, althou

39 Molecular profiling is increasingly being used to guide cancer patient care, es

40 y economically extractable levels.Lithium is increasingly being utilized for modern technology in the

41 e and NAD(+) concentrations decline, DBC1 is increasingly bound to PARP1, causing DNA damage to accum

42 ent years, scaffold hopping calculations are increasingly carried out at the level of scaffolds rathe

43 Insufficient sleep increasingly characterizes modern society, contributing

44 It is increasingly clear that plants perceive and respond to o

45 It is thus becoming increasingly clear that start codon selection is regulat

46 he Cancer Genome Atlas (TCGA) data have been increasingly collected.

47 Yet, increasingly, combined synthetic/spectroscopic/computati

48 It is an increasingly common and disabling fibroproliferative dis

49 Food allergy is an increasingly common health problem in Western population

50 his phenomenon is associated with a range of increasingly common human disorders, including Alzheimer

51 ment of very large CyTOF datasets, which are increasingly common in clinical studies and cancer studi

52 ily large, N-dimensional datasets, which are increasingly common in modern image acquisition.

53 itical debate concerning moralized issues is increasingly common in online social networks.

54 e examination of DNA methylation is becoming increasingly common in psychological studies.

55 l knowledge of the deleterious effects of an increasingly common natural toxin.

56 ather than emergency procedure has become an increasingly common practice in children.

57 Minimally invasive colectomy (MIC) is an increasingly common surgical procedure.

58 ted reproductive therapies (ART) have become increasingly common worldwide and numerous retrospective

59 Multiomics experiments are increasingly commonplace in biomedical research and add

60 olanzapine versus placebo groups using eight increasingly complex competing mixed-effects models for

61 y role of these calculations in interpreting increasingly complex experiments.

62 rotocol, a clinically guided protocol, and 3 increasingly complex pharmacogenomic-guided protocols.

63 Immunologists are attempting to answer increasingly complex questions concerning phenomena that

64 reby permitting the bottom-up engineering of increasingly complex reaction networks from simple build

65 mechanisms of CME, and the field is becoming increasingly complex, with several hundred new publicati

66 g subregion (GMS), artemisinin resistance is increasingly compounded by partner drug resistance, caus

67 Diabetic cardiomyopathy (DCM) has been increasingly considered as a main cause of heart failure

68 s at neurons, more recently glial P2X7Rs are increasingly considered as indirect causes of neuronal e

69 HD1 to PHD3 are molecular oxygen sensors and increasingly considered as putative therapeutic targets.

70 an endogenous energy source and storage are increasingly considered as signaling molecules regulatin

71 ome a construct that Western scientists have increasingly considered for conducting culturally releva

72 Inflammation is increasingly considered to be a pathologic mediator of t

73 pletion, expression of the two genes becomes increasingly correlated.

74 he fast growing genomic data, it is becoming increasingly critical for biology researchers to be able

75 and comparative genomic context is becoming increasingly crucial to make full use of the data.

76 Developing countries are increasingly decentralizing forest governance by grantin

77 and how theories of acute oxygen sensing are increasingly dependent on functional interaction within

78 is by mass spectrometry (imaging) has become increasingly deployed in preclinical and clinical resear

79 wheat bread and whole grain bread, qualities increasingly desired by consumers in this segment.

80 -the Boston criteria, which have resulted in increasingly detected disease during life.

81 ise size and shape control, yet this becomes increasingly difficult at sizes of approximately 10 nm.

82 Conservation of species and ecosystems is increasingly difficult because anthropogenic impacts are

83 decreased over the past 5 decades, making it increasingly difficult to demonstrate significant benefi

84 esno's land and water management have become increasingly disconnected in recent years, with the harv

85 Carry-over effects are increasingly documented although underlying mechanisms r

86 Increasingly, donation after cardiac death (DCD) donors

87 drylands, and that deep soil layers could be increasingly dry during the growing season.

88 using optics alone promises a route towards increasingly dynamic systems, where the geometry and fun

89 d dietary pattern scores was associated with increasingly elevated ORs for unhealthy obesity, with in

90 cal and electronic equipment (EEE), which is increasingly embedded in other products, notably passeng

91 Small RNAs are increasingly emerging as transgenerational carriers of e

92 , a post-translational modification with the increasingly eminent role in normal physiology and disea

93 l public reporting and payment programs have increasingly emphasized the measurement of outcomes (suc

94 an area in its infancy which we believe will increasingly engage the computational community: predict

95 Moreover, it is increasingly evident that PTEN deficiency disrupts the f

96 In the past decade, it has become increasingly evident that several important developmenta

97 ized pathogen of debilitated older people is increasingly evident.

98 migratory animals that rely on wetlands are increasingly exposed to elevated salinity on their nonbr

99 Interventional cardiologists are increasingly exposed to radiation-induced diseases like

100 Soil systems are being increasingly exposed to the interactive effects of biolo

101 Actuator operation in increasingly extreme and remote conditions requires mate

102 With this result at hand, the field has increasingly focused on the difficult question of where

103 Society increasingly focuses on managing nature for the services

104 Natural silks are considered increasingly for medical applications because they are b

105 rkholderia pseudomallei, is being recognised increasingly frequently.

106 Thus, use of endogenous targeting systems is increasingly gaining momentum.

107 vices (IPBES) recognize the importance of an increasingly global, quantitative and comprehensive appr

108 spectral clustering algorithm to cluster the increasingly growing number of protein structures with p

109 that development of mass spectrometers with increasingly high resolution and novel couplings to both

110 Despite an increasingly higher-risk profile of patients, outcomes h

111 tation for both natural and human systems is increasingly important as a coping strategy due to the r

112 Overall, drug repurposing could become increasingly important as a way of advancing allergy and

113 tural resilience of reef systems will become increasingly important as the frequency of disturbances

114 mortalized mammalian cell lines are becoming increasingly important as therapies.

115 Thus, it is increasingly important but not yet standard to combine R

116 of patients with HIV and NAFLD are becoming increasingly important for accurately counselling of the

117 ries to make rigorous assessment for frailty increasingly important for hematologic oncologists.

118 Computational models are increasingly important in confronting and overcoming the

119 Agave fructans are increasingly important in food industry and nutrition sc

120 Whole grain teff flour becomes increasingly important in healthy food market, and has b

121 ble and stretchable electronics are becoming increasingly important in many emerging applications.

122 ratures, this seemingly fundamental limit is increasingly important in the laboratory.

123 biologically relevant molecules is becoming increasingly important in the pharmaceutical industry.

124 ring-opening process is described for these increasingly important NHC molecules, which are generall

125 Therefore, the targeting of PSMA has become increasingly important over the last decade.

126 itrogen-Vacancy centers, which has become an increasingly important platform for quantum information

127 ption will aid us in the quest to tackle the increasingly important problem of hearing loss in our ag

128 of ion-selective electrodes, have played an increasingly important role in chemical and biochemical

129 Graduate and professional education play an increasingly important role in economic inequality and e

130 It is likely that TAVR will play an increasingly important role in the management of these p

131 Lipid nanodiscs are playing increasingly important roles in studies of the structure

132 ism faces-come under greater scrutiny, it is increasingly important to connect the macroscopic faces

133 The detection of those targets is becoming increasingly important to yield the full function of nov

134 icles such as protons and carbon ions are an increasingly important tool in radiotherapy.

135 ts indicate that dissolution dynamics become increasingly important with increasing adsorption affini

136 nding interaction of (SO2)O...H(H2O) becomes increasingly important with the increase of droplet size

137 Methods to characterize TIL biology are increasingly important, and the authors offer several ar

138 his type of microecological study has become increasingly important, especially with the emergence of

139 he different compartments of kidneys becomes increasingly important.

140 to detect minimal residual disease (MRD) is increasingly influencing treatment paradigms.

141 nthetic and biosynthetic studies will become increasingly interdependent.

142 al friendly, these systems are thus becoming increasingly interesting for the design of new energy st

143 al system uses a similar strategy to achieve increasingly invariant representations of the visual wor

144 cessing strategy to achieve higher-level and increasingly invariant representations of the visual wor

145 yed in basic and translational research, and increasingly is also used privately in sport, the milita

146 are delivered in-person; however, treatment increasingly is being disseminated through community- an

147 n the maintenance of cholesterol homeostasis increasingly is recognized.

148 in sequencing technology continue to deliver increasingly large molecular sequence datasets that are

149 T2D, and patients with T2D will comprise an increasingly large proportion of the CVD population.

150 arkinson's disease, are thought to spread to increasingly larger areas of the brain through a prion-l

151 ontributions to human health and disease has increasingly led investigators to examine the microbiome

152 a porous altered layer, flow channeling, and increasingly limited calcite dissolution.

153 If the frequency of such event is increasingly linearly between these two periods, then in

154 and nuclear-cytoplasmic transport have been increasingly linked both to disease and ageing.

155 izophrenia, a mental health disorder that is increasingly linked to oxidative stress.

156 sible, but manufacturing and manipulating an increasingly long scaffold strand remains a challenge.

157 individual BSA monomers in bulk solution had increasingly lower conformational stability at higher te

158 ages in short, successive cycles (i.e., that increasingly minimized uncertainty about the nature of u

159 e activation promotes tetrabromination of an increasingly more electron-deficient arene before the un

160 traits and physiological markers has become increasingly more important, as this may lead us closer

161 s household net worth increased, youths were increasingly more likely to undergo an eye examination b

162 Fluorine substituents gave rise to increasingly more stabilizing interactions with more ele

163 Hospitals are increasingly motivated to reduce length of stay (LOS) af

164 interaction analyses have revealed that our increasingly obesogenic environment might be amplifying

165 omes are added, identical read sequences are increasingly observed, and compression becomes more effi

166 to specific targeted therapies are performed increasingly often.

167 show that white matter connectivity becomes increasingly optimized for a diverse range of predicted

168 ion of ventricular tachycardia (VT) is being increasingly performed; yet, there is often confusion re

169 e cyanobacterium Microcystis sp. have become increasingly pervasive in the San Francisco Estuary Delt

170 Our calculated velocities are in increasingly poor agreement with those of the lower mant

171 erence from real-time input data is becoming increasingly popular and may be one of the potential pat

172 chine learning and correlational methods are increasingly popular for inferring networks from co-occu

173 Mobile health interventions are increasingly popular in pediatrics; however, it is uncle

174 exture analysis of medical images has become increasingly popular in studies investigating diagnosis,

175 Although mixed methods research is becoming increasingly popular in the area of coronary artery dise

176 Fragment-based drug discovery is an increasingly popular method to identify novel small-mole

177 Fragment-based lead discovery is becoming an increasingly popular strategy for drug discovery.

178 thods within 1 program of study, is becoming increasingly popular to allow investigators to explore p

179 S) with "time to event" outcomes have become increasingly popular, predominantly in the context of ph

180 hat convey scientific concepts or themes are increasingly popular.

181 However, engineering an increasingly positive charge in a critical phosphorylati

182 calation hypothesis posits that predation by increasingly powerful and metabolically active carnivore

183 prove, automated data analysis may become an increasingly practical supplement to the ACS.

184 common and interpretation is complicated by increasingly precise data obtained via multicollector ma

185 species was S. aureus and MRSA infection is increasingly prevalent.

186 e via nonverbal gestures (flips/shrugs), and increasingly produce verbal acknowledgments of ignorance

187 Ecosystems are increasingly prone to climate extremes, such as drought,

188 It is increasingly recognised, however, that clinical and path

189 Takotsubo cardiomyopathy is an increasingly recognized acute heart failure syndrome pre

190 t main coronary artery (LMCA) compression is increasingly recognized as a cause of angina in pulmonar

191 f mRNA splicing, processing and stability is increasingly recognized as a critical control point in d

192 ulation of ion channel activity by lipids is increasingly recognized as a fundamental component of ce

193 ukoencephalopathies and leukodystrophies are increasingly recognized as a heterogeneous group of diso

194 tween the vasculature and retinal neurons is increasingly recognized as a major factor contributing t

195 Medication nonadherence has been increasingly recognized as a major impediment to achievi

196 SD1) regulates histone methylation and it is increasingly recognized as a potential therapeutic targe

197 Although Mycoplasma genitalium is increasingly recognized as a sexually transmitted pathog

198 Chronic pain is increasingly recognized as an important comorbidity of H

199 The endosome is increasingly recognized as an important crossroad for AP

200 Coinfections are increasingly recognized as important drivers of disease

201 Common ocular pathogens, such as HSV-1, are increasingly recognized as major contributors to visual

202 Exposure to and connection with nature is increasingly recognized as providing significant well-be

203 Long noncoding RNAs (lncRNAs) are increasingly recognized as vital components of gene prog

204 The microbiota is increasingly recognized for its ability to influence the

205 arid and semi-arid drylands of the world are increasingly recognized for their role in the terrestria

206 Antibody-mediated rejection (AMR) is an increasingly recognized form of lung rejection.

207 chronic malfunction of the UPR(MT) Given the increasingly recognized role of mitochondrial quality co

208 onic liver failure (ACLF) in cirrhosis is an increasingly recognized syndrome characterized by acute

209 However, it is now increasingly recognized that neutrophils are a heterogen

210 It is increasingly recognized that organelle contacts have a v

211 Single cells are increasingly recognized to be capable of healing wounds.

212 nally considered a motor structure, has been increasingly recognized to play a role in regulating exe

213 gh the importance of network connectivity is increasingly recognized, identifying synapses remains ch

214 The pattern of mixed TCMR and ABMR was increasingly recognized.

215 etiology of neurodevelopmental disorders is increasingly recognized.

216 ey age, children's reasoning about testimony increasingly reflects an ability not just to detect impe

217 ral wetlands, we tested whether species were increasingly related as flooding duration intensified.

218 food and feedstock in particular has become increasingly relevant as these toxins, such as ochratoxi

219 PCR-based reports are increasingly relevant for RSV surveillance and determini

220 tronic structure calculations are playing an increasingly relevant role in this search, but large-sca

221 tion and noncovalent interactions has become increasingly relevant.

222 As biomedical research increasingly relies on computational, mathematical, and

223 Modern neuroscience increasingly relies on custom-developed software, but mu

224 Biological data and knowledge bases increasingly rely on Semantic Web technologies and the u

225 e, rigidity, and postural abnormalities) and increasingly reported problems in basic daily activities

226 europsychiatric, and malignant diseases were increasingly reported, but confirmation of their link wi

227 R) studies performed on this model have been increasingly reported, especially in the field of neuros

228 oring of material degradation and cracks are increasingly required for characterizing the structural

229 Curing infections increasingly requires antimicrobials that are broader sp

230 terials into multilayer device architectures increasingly requires understanding the behavior of nonc

231 Increasingly, research is showing how brain disease or p

232 juice resemble those found on grapes, these increasingly resemble fungi present on vine bark as the

233 on was not driven by sequential emergence of increasingly resistant subclades.

234 time when almost every pathogen is becoming increasingly resistant to antimicrobials, we show that t

235 usion through tissue, which normally becomes increasingly restricted and anisotropic in the brain dur

236 Liver sections were processed in a series of increasingly rigorous extraction buffers to separate pro

237 With transplantation becoming an increasingly routine form of treatment for diverse popul

238 Modern plant breeders increasingly seek to circumvent this process to produce

239 Rather, the spatial tuning of inputs became increasingly similar across repeated traversals of the e

240 he resolution of fibrosis, where they became increasingly similar to tissue-resident alveolar macroph

241 ssive insertion of new cell wall by building increasingly smaller concentric rings of peptidoglycan t

242 The fragmentation of the material into increasingly smaller pieces is an unavoidable stage of t

243 This could partly explain the increasingly smaller sex difference in the prevalence of

244 tection strategies have allowed SRS to probe increasingly smaller volumes and shorter time scales.

245 ion potentials, these two transitions become increasingly smeared together, so measuring a clear dist

246 dened our analytical window and have enabled increasingly sophisticated data processing strategies, i

247 While increasingly sophisticated immunotherapy targeting solub

248 Increasingly sophisticated models based on these princip

249 Despite our increasingly sophisticated understanding of mechanisms e

250 eterogeneous data is how best to interrogate increasingly specific subphenotypes while retaining stat

251 s signaling through Src, PI3K, and Rac1, and increasingly stiff collagen promoted dispersive epitheli

252 , proximate effects of temperature played an increasingly stronger role than intrinsic constraints fo

253 has been assumed to be static, in vitro data increasingly suggest that cell activity modulates vesicl

254 n of genetic abnormalities, emerging studies increasingly suggest that immune dysfunction is a viable

255 d in the science of probability and has been increasingly supplementing or replacing traditional appr

256 cent spectroscopic and computational studies increasingly support iron as the site of catalytic activ

257 As the human brain develops, it increasingly supports coordinated control of neural acti

258 The modern patient is increasingly susceptible to bacterial infections includi

259 n diagnosis, and has already begun to inform increasingly targeted and individualised therapies.

260 Increasingly, the statistical and epidemiologic literatu

261 activity as an energetic metabolite, BHB is increasingly understood to have cellular signaling funct

262 to 2015 as compared to 1985-1999, suggesting increasingly unfavourable post-fire growing conditions,

263 Institutional databases worldwide increasingly use the WHO International Classification of

264 owever, molecular-based techniques have been increasingly used and relied on to determine evolutionar

265 Surgical site infection (SSI) rates are increasingly used as a quality metric.

266 Direct oral anticoagulants are increasingly used for a wide range of indications.

267 Accordingly, a multimodality approach is increasingly used for diagnostic workup and supported by

268 -3,4-methylenedioxymethamphetamine (MDMA) is increasingly used for its perceived emotional effects (e

269 artial nitritation and Anammox processes are increasingly used for nitrogen removal from anaerobic sl

270 ral nervous system-targeted medications) are increasingly used for treatment of functional gastrointe

271 flame retardants and plasticizers (PFRs) are increasingly used in consumer goods, from which they can

272 are random oligonucleotide barcodes that are increasingly used in high-throughput sequencing experime

273 RATIONALE: Noninvasive ventilation (NIV) is increasingly used in patients with acute respiratory dis

274 Noninvasive imaging technologies are increasingly used in preclinical drug research for the p

275 ture for cell lines and cell types are being increasingly used in publications by the scientists.

276 High-flow nasal cannula is increasingly used in the management of respiratory failu

277 antages relative to conventional FOBT and is increasingly used relative to that test.

278 Metagenomic sequencing is increasingly used to decipher the fungal populations pre

279 iptional regulatory networks (TRNs) has been increasingly used to dissect the nature of gene regulati

280 Genomic-scale sequence alignments are increasingly used to infer phylogenies in order to bette

281 These networks are increasingly used to inform strategies to prevent and co

282 ACKGROUND DATA: Nationwide hospital data are increasingly used to investigate surgical outcomes.

283 Opioids are increasingly used to manage chronic pain, and chronic op

284 Environmental footprints are increasingly used to quantify and compare environmental

285 e processing of electronic health records is increasingly used to study mental health conditions and

286 Tree rings are increasingly used to study such responses.

287 Phosphoproteomic experiments are increasingly used to study the changes in signaling occu

288 Bisphenol F (BPF) and bisphenol S (BPS) are increasingly used to substitute bisphenol A (BPA), a wid

289 demic and because immunomodulatory drugs are increasingly used to treat autoimmune diseases and cance

290 ensity-modulated radiation therapy (IMRT) is increasingly used to treat locally advanced non-small-ce

291 The dopamine partial agonist aripiprazole is increasingly used to treat pathologies for which other a

292 ar knot topologies increases, it will become increasingly useful for chemists to adopt the knot termi

293 ients with a history of CAD, SPECT was being increasingly utilized in patients with milder CAD.

294 mian immunodeficiency virus (SIV) provide an increasingly utilized model of pathogenesis due to clini

295 Catheter ablation is an increasingly utilized treatment strategy and has evolved

296 water storage after precipitation events are increasingly valuable as global water resources continue

297 The rise in PSSA makes penicillin an increasingly viable treatment option.

298 Adults and adolescents increasingly view cannabis as harmless, and some can use

299 tudy due to higher plant productivity in the increasingly warm summers.

300 Zebrafish neuromast development is increasingly well understood, but neither zebrafish nor