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1 ose and patients often present with advanced incurable disease.
2 o the development of an indolent and largely incurable disease.
3 er (SCLC) at advanced stage is considered an incurable disease.
4  potential opportunity for treatment of this incurable disease.
5 therapeutic target for the treatment of this incurable disease.
6 utes a potential therapeutic target for this incurable disease.
7 r therapeutic intervention in this otherwise incurable disease.
8 us cell cancer (ESCC) present with advanced, incurable disease.
9 rly drug development trials in children with incurable disease.
10         Metastatic melanoma remains a mostly incurable disease.
11  radiotherapy, making radioresistant CRPC an incurable disease.
12 vival time, myeloma continues to be a mostly incurable disease.
13 ise as a therapeutic strategy to combat this incurable disease.
14 hronic lymphocytic leukemia (CLL) remains an incurable disease.
15  novel therapeutic target for this currently incurable disease.
16 in the development of new therapies for this incurable disease.
17 etastases and new therapeutic avenues for an incurable disease.
18 y lead to more effective treatments for this incurable disease.
19                  Multiple myeloma remains an incurable disease.
20  screening are not precursors of advanced or incurable disease.
21 f failed apoptosis of B cells and remains an incurable disease.
22 on of metastatic ability leads to clinically incurable disease.
23                  Malignant gliomas remain an incurable disease.
24 eatic adenocarcinoma present with surgically incurable disease.
25 allogeneic cellular therapy for this largely incurable disease.
26 e patients who go on to develop progressive, incurable disease.
27 d achieve improved outcome in this presently incurable disease.
28 e useful in the management of this presently incurable disease.
29 equired for the management of this otherwise incurable disease.
30 o offer unproven procedures to patients with incurable diseases.
31 peutic alternative for many debilitating and incurable diseases.
32 s to vaccination, implantation, and treating incurable diseases.
33 ous potential for clinical treatment of many incurable diseases.
34   Muscular dystrophies are common, currently incurable diseases.
35 ising therapeutic targets in these currently incurable diseases.
36 in advancing cures for a number of otherwise incurable diseases.
37 icity and dosing of potential treatments for incurable diseases.
38                                    It was an incurable disease 50 years ago, but approximately 70% of
39    Alzheimer's dementia is a devastating and incurable disease afflicting over 35 million people worl
40 east cancer has a high risk of recurrence to incurable disease and needs improved prognostic and ther
41      Recurrent breast cancer is typically an incurable disease and, as such, is disproportionately re
42                However MCL remains a largely incurable disease, and following relapse, it can be a ch
43               Lung cancer is still a largely incurable disease; annual lung-cancer mortality in women
44  leads to a typical clinical presentation of incurable disease at initial diagnosis.
45        Most patients diagnosed with EAC have incurable disease at the time of detection.
46  leads to a typical clinical presentation of incurable disease at the time of diagnosis.
47 t time, AML remains a devastating and mostly incurable disease, but the combination of optimized chem
48 ystrophic epidermolysis bullosa (RDEB) is an incurable disease caused by mutations in the gene encodi
49 Ataxia Type 3 (SCA3), one of nine inherited, incurable diseases caused by similar mutations.
50  Pulmonary arterial hypertension (PAH) is an incurable disease characterized by a progressive increas
51     Chronic lymphocytic leukemia (CLL) is an incurable disease characterized by accumulation of clona
52                      HIV-1 causes a chronic, incurable disease due to its persistence in CD4+ T cells
53                 Furthermore, CLL is still an incurable disease due to the persistence of residual leu
54          Mantle cell lymphoma is a generally incurable disease for which blood or marrow transplantat
55            Malignant mesothelioma remains an incurable disease for which immune-modulatory therapies,
56 ic and induced) for regenerative medicine of incurable diseases, immunotherapy and blood transfusions
57 ioblastoma multiforme (GBM) remains a mainly incurable disease in desperate need of more effective tr
58    Amyloidoses are devastating and currently incurable diseases in which the process of amyloid forma
59               HIV/AIDS remains a chronic and incurable disease, in spite of the notable successes of
60 re toxic, causing or contributing to severe, incurable diseases including Alzheimer's and prion disea
61 mation of amyloid fibrils is associated with incurable diseases including Alzheimer's, Parkinson's, a
62 sfolded proteins are the hallmark of several incurable diseases, including Alzheimer's disease, type-
63 velopment of therapeutic strategies to treat incurable diseases of the nervous system, including trau
64 y arterial hypertension (PAH) is a medically incurable disease resulting in death from right ventricu
65  study point to new drug targets in CRPC, an incurable disease state which remains the chief therapeu
66 minal illness acknowledgment, recognition of incurable disease status, knowledge of the advanced stag
67 onic lymphocytic leukemia (B-CLL) remains an incurable disease that requires innovative new approache
68                      Although SMA remains an incurable disease to date, recent advances in the field
69  Adult T-cell leukemia/lymphoma (ATLL) is an incurable disease where most patients succumb within the
70 thought to represent cures in this otherwise incurable disease with conventional modalities.
71 Low-grade lymphomas are generally considered incurable diseases with current standard therapies.
72 ting peripheral neuropathies are progressive incurable diseases without effective treatment.

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