ライフサイエンスコーパス: indanone

1 h unfavorable equilibrium positions (e.g., 1-indanone).

2 (3'-propanoic acid)-7abeta-methylhexahydro-5-indanone.

3 face of C(78) was synthesized from 4-bromo-1-indanone.

4 r the archetypal aldol cyclotrimerization of indanone (2) in aprotic solvents, and a strong dependenc

5 erial to provide the desired 5,6-dimethoxy-1-indanone 5c in good overall yield (65%) and the formatio

6 erall yield of ( approximately 65%) from the indanone 5c.

7 ons) from commercially available 4-methoxy-1-indanone 60 and proceeded in 22% overall yield.

8 ctive positive allosteric modulator biphenyl-indanone A (BINA) modulates excitatory neurotransmission

9 PAMs with the mGluR2 selective PAM biphenyl indanone-A failed to potentiate glutamate responses thro

10 ch has also been applied in the synthesis of indanone analogues of Paucifloral F.

11 pendent reaction yielding 71% of 5-methoxy-2-indanone and 29% of diols are observed; the half-life of

12 C bond-formation reaction between 6hydroxy-1-indanone and aromatic aldehydes is indicated by cooperat

13 Indanones and 2-cyclopentenones have been successfully p

14 tion of the N-methyl imines of 3-substituted indanones and 4-substituted tetralones could be accompli

15 Indanones and coumarins are important intermediates for

16 y at room temperature, producing substituted indanones and fluorenones through a C2-C6 cyclization pa

17 lidenecycloalkanones derived from tetralone, indanone, and benzosuberone to afford 2-aryl-3-bromofura

18 of trifluoromethylated arylpropanoic acids, indanones, and dihydrocoumarins using Friedel-Crafts alk

19 1,3-cis-Disubstituted-2-indanones are formed preferentially when the benzylic su

20 tiomers of a series of tertiary alpha-aryl-1-indanones are readily accessed from the corresponding al

21 to the chemo- and regioselective assembly of indanone arrays and to the total synthesis of a recently

22 pproach for the synthesis of enantioenriched indanones by asymmetric carbonyl-ene/intramolecular Heck

23 The preparation of indanones by the intramolecular acylation of 3-arylpropa

24 characterize lithium enolates derived from 1-indanone, cyclohexanone, and cyclopentanone in solution.

25 o a series of alpha-arylations of tetralone, indanone, cyclopentanone, and cyclohexanone derivatives.

26 substituted indanones or alpha-exo-methylene indanones depending on the base used.

27 fficient two-step method for the assembly of indanone derivatives starting from a simple vinyl arene

28 alkenylbenzaldehydes to afford phthalide and indanone derivatives, respectively, in moderate to good

29 catalytic salt was found to be active when 1-indanones derivatives were directly employed in the reac

30 While most of indanone-derived N-benzylpyridinium salts 2 revealed to

31 ron-donating core and 1,1-dicyanomethylene-3-indanone electron-withdrawing end groups.

32 facile approach toward natural and unnatural indanones has been developed, featuring a solid-supporte

33 the end-capping group 1,1-dicyanomethylene-3-indanone (IC).

34 phene end-capped with 1.1-dicyanomethylene-3-indanone (IDIC), as a multifunctional interlayer, which

35 vides an efficient route to 3 from 4-bromo-1-indanone in 12 steps.

36 zation at 60 degrees C to form substituted 2-indanones in good overall yields.

37 Substituted indenes may be prepared from 2-indanones in high yields by Horner-Wadsworth-Emmons reac

38 ituted 3-(2-iodoaryl)propanenitriles affords indanones in high yields.

39 1-Indanones, indeno indenes, and indeno furanones were acc

40 o the total synthesis of a recently isolated indanone marine natural product.

41 l: 1-phenylethanol, alpha-ionone, 3-methyl-1-indanone, o-(chloromethyl)phenyl sulfoxide, o-(bromometh

42 and (6) protonation by H(2)O to produce the indanone or 2-cyclopentenone.

43 itions, these triflates are transformed into indanone or indene derivatives depending on which substi

44 This strategy involves converting an indanone or tetralone (4) to a cyanohydrin (3) which is

45 ther enantiomerically enriched 3-substituted indanones or alpha-exo-methylene indanones depending on

46 can lead to either chalcone-type products or indanone products.

47 t base-catalyzed condensation of 6-hydroxy-1-indanone with substituted benzaldehydes and to compare t

48 edure affords highly substituted indenes and indanones with excellent chirality transfer from the opt

49 form cis- and trans-1,3-dimethyl-1-phenyl-2-indanones with the yield of ca. 60%.