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1 somes to increase protein synthesis in a CAP-independent manner.
2 nd D76N beta2-m fibril formation in a Ca(2+)-independent manner.
3 b also promotes CZ targeting but in a Sema3D-independent manner.
4  to modulate cell contraction in a RhoA-ROCK-independent manner.
5 t it represses cAMP signalling in an agonist-independent manner.
6 ectly interacts with the beta2AR in a ligand-independent manner.
7 itors that can form 3D colonies in a hormone-independent manner.
8 Mdm2 results in genomic instability in a p53-independent manner.
9 target genes in a methyltransferase activity-independent manner.
10  suppressing tumor growth in an inflammasome-independent manner.
11 ly in a farnesylation-dependent but membrane-independent manner.
12 ulent P. sojae strains may function in an SA-independent manner.
13 ion of viral structural proteins in a factor-independent manner.
14 ted against diet-induced NASH, in an obesity-independent manner.
15 tion and cell proliferation in a bromodomain-independent manner.
16 onse is impaired in a type I and type II IFN-independent manner.
17 hibited HIV-1 release in a Vpu- and tetherin-independent manner.
18 gands in a rapid, reversible, titratable and independent manner.
19 hypoxia inducible factor 1alpha (HIF-1alpha)-independent manner.
20 n the airways in an IL-33-dependent but TRL4-independent manner.
21 romoter is activated by the pathogen in a SA-independent manner.
22  production in MDMs in a type-I IFN- and TLR-independent manner.
23 ssion can occur in a physical and signalling-independent manner.
24 ron production in a STING-dependent but cGAS-independent manner.
25  ProP concentrated at the cell poles in a CL-independent manner.
26 lix domain (WHD) and binds DNA in a sequence-independent manner.
27 nhanced LTP formation in a protein-synthesis-independent manner.
28 D4(+) and CD8(+) T cell activation in a Treg-independent manner.
29 okine expression in a necroptosis and kinase-independent manner.
30  and IL-13 expression in the lung in a STAT6-independent manner.
31 ired B cell survival and activation in an Fc-independent manner.
32 tion of PKCzeta in a CD14-dependent and TLR4-independent manner.
33 crophage function in an LpSpl-dependent and -independent manner.
34 can respond to unrelated infections in an Ag-independent manner.
35 nted allergic airway inflammation in a STAT6-independent manner.
36 K9me3 occur in an oxygen-dependent but HIF-1-independent manner.
37 f anthocyanins, in a tissue- and development-independent manner.
38 is, and accelerates healing in a DNA-binding independent manner.
39 h Tdp1 was recruited to only 5' DSBs in a Ku-independent manner.
40 ulated by the RNA chaperone, Hfq, in an RpoS-independent manner.
41 llar granule neuron precursor cells in a p53-independent manner.
42 alytic activity of VRK2 in a kinase activity-independent manner.
43  of DNA replication in an Rb phosphorylation-independent manner.
44 breast cancer cells in a histone methylation-independent manner.
45  hematopoietic cells in an ATM-dependent or -independent manner.
46  the absence of ADP in an adenosine receptor-independent manner.
47 urons of Xenopus commonly function in a cAMP-independent manner.
48  and B cell survival are impaired in a BclxL-independent manner.
49 ts with the BR receptor BRI1 in vivo in a BR-independent manner.
50 ylation during ischemia-reperfusion in a GSH-independent manner.
51 negatively charged membranes in a nucleotide-independent manner.
52 tely activated by aa-readdition in an mTORC1-independent manner.
53 de at newly formed adhesion sites in a talin-independent manner.
54 ientational correlation functions in a model-independent manner.
55 colysis with cytoskeletal dynamics in an AKT-independent manner.
56 ps eIF4A onto polypurine sequences in an ATP-independent manner.
57 phocyte activation in a Toll-like receptor 2-independent manner.
58 n to block cancer progression in an androgen-independent manner.
59 tion and maturation of IL1beta/18 in a LUBAC-independent manner.
60 om the inner membrane to the OM in an energy-independent manner.
61 nation in a chromatin-dependent and sequence-independent manner.
62 e-delimited Gbetagamma subunits in a voltage-independent manner.
63 the RAS promotes colitis in a blood pressure independent manner.
64       S1P exerts its effects in S1P receptor-independent manner.
65    However, assembly proceeds in a chaperone-independent manner.
66 enous postsynaptic TrkC in a tyrosine kinase-independent manner.
67 decreased mitochondrial DNA in a HIF1/2alpha-independent manner.
68 behaviors in a light-dependent but circadian-independent manner.
69 bution of HPL-2 can be achieved in an H3K9me-independent manner.
70 strong predictor of fibrosis in an aetiology-independent manner.
71 o increased cellular transformation in a p53-independent manner.
72 reduce CN(-) to C1-C3 hydrocarbons in an ATP-independent manner.
73 operties of the resulting fibrils in a polyQ-independent manner.
74 ed the production of IL-10 in a cell-contact-independent manner.
75 antibiotic exposure in an idiosyncratic dose-independent manner.
76 rs their capacity for growth in an anchorage-independent manner.
77 t Mot1 primes TBP:NC2 displacement in an ATP-independent manner.
78 t activates the alternative pathway in an Fc-independent manner.
79 ndense in the nucleoplasm in a transcription-independent manner.
80 ay inhibit their expression in a methylation-independent manner.
81  specificity and inhibits Src in an activity-independent manner.
82  and BAX to guarantee cell survival in a p53-independent manner.
83 nylate cyclase (Cyr1) interact in a nutrient-independent manner.
84 NO) in guard cells in an abscisic acid (ABA)-independent manner.
85 ent a target for DMD therapy in a dystrophin-independent manner.
86 s highly associated with asthma, in an IL-10-independent manner.
87  function of isolated platelets in a contact-independent manner.
88 ntrast, HDAC1 inhibits HSF1 in a deacetylase-independent manner.
89 on in ECs inflamed with TNFalpha in an ATP7A-independent manner.
90  AKT activation in an integrin-linked kinase-independent manner.
91 rotects RhoU from ubiquitination in a kinase-independent manner.
92 ptosis mediated by the receptor DCC in a p53-independent manner.
93 hate nucleotidohydrolase in an interleukin 6-independent manner.
94 ir potential to interact with UVR8 in a UV-B-independent manner.
95 tabilizing the GLI1 protein in a demethylase-independent manner.
96 naling promotes male differentiation in a RA-independent manner.
97 ble and particulate antigens in an IFN-gamma-independent manner.
98 can structures in a sequence order- and size-independent manner.
99 M phases of the cell cycle in a largely size-independent manner.
100 and harbor more long-range contacts in a sex-independent manner.
101 ogen-derived inflammatory cytokines in an Ag-independent manner.
102 PDs by energy transfer to DNA in a radiation-independent manner.
103 aryotic initiation factor 2alpha (eIF2alpha)-independent manner.
104 the mitochondrial apoptosis pathway in a p53-independent manner.
105 cells restricted HCV infection in a genotype-independent manner.
106  carbohydrate-recognition domain in a Ca(2+)-independent manner.
107 ts influence genome functions in a transport-independent manner.
108 oteasomes in an adenosine triphosphate (ATP)-independent manner.
109 astogenesis in both a contact-dependent and -independent manner.
110  and is delivered to endosomes in a clathrin-independent manner.
111 IF2alpha-mediated transcription in a hypoxia-independent manner.
112 n, the interaction increases in a Src kinase-independent manner.
113 lated cytokines from keratinocytes in a PAR2 independent manner.
114 t its regulatory function in an isopeptidase-independent manner.
115 lic benefits of RYGB partly in a weight loss-independent manner.
116 els and transporters in living cells in a pH-independent manner.
117 y binds to polyubiquitin chains in a linkage-independent manner.
118 gating in an amyloid beta (Abeta) production-independent manner.
119 killing of target cells in a T cell receptor-independent manner.
120  a vascular endothelial growth factor (VEGF)-independent manner.
121 ) in their 5' UTR can be translated in a cap-independent manner.
122 ressor in the intestinal epithelium in a Wnt-independent manner.
123 nes, Arl2 binds to membranes in a nucleotide-independent manner.
124 sequent proteasomal degradation in an oxygen-independent manner.
125 -motor circuits are assembled in an activity-independent manner.
126 maturation by binding pre-miR-10a in a DICER-independent manner.
127 sion of IGFBP3 in both DNMT3a-dependent and -independent manner.
128  dose-dependent but pyruvate kinase activity-independent manner.
129 d production of IFN-gamma and IL-4, in an Ag-independent manner.
130  retention of male structures in an androgen-independent manner.
131 cleosomes in a DNA replication- and sequence-independent manner.
132  lamellipodium buckles upward in a myosin II-independent manner.
133 transactivate FOXM1 target genes in a kinase-independent manner.
134 ific expression in a LFS-dependent but auxin-independent manner.
135 ML stem/progenitor cells in a BCR-ABL kinase-independent manner.
136 stance from falling to low levels in a light-independent manner.
137 er a broad range of length scales in a model-independent manner.
138 nduced senescence phenotypes in a PARylation-independent manner.
139 V-1, also prevents virion assembly in a BST2-independent manner.
140 ammals) regulate circadian timing in a light-independent manner.
141 the NuRD complex, in a glucose concentration-independent manner.
142 in turn activates IMM constriction in a Drp1-independent manner.
143 after exposure to A. fumigatus in a dectin-1-independent manner.
144  oncogenic translocations in a transcription-independent manner.
145 d upon DNA damage and is translated in a CAP-independent manner.
146 e damaged DNA after UV irradiation in a DDB2-independent manner.
147 the secretion of IFN-gamma in a cell contact-independent manner.
148 e death of infected plants in a largely NBR1-independent manner.
149  Fosb and Fos AP-1 factors in a beta-catenin-independent manner.
150 ication processes where Dl signals in an ubi-independent manner.
151  permit disaggregation to occur in an energy-independent manner.
152 biquitinating cyclin D1 in a phosphorylation-independent manner.
153 lization in a glycogen synthase kinase 3beta-independent manner.
154 bilization of Ctn RNA occurred in an editing-independent manner.
155 nd actomyosin dynamics in VSMCs in a mitosis-independent manner.
156 as shown to be able to activate Dl in an ubi-independent manner.
157  at heterochromatic regions in a replication-independent manner.
158 the translation of viral late mRNAs in a cap-independent manner.
159 o host resistance in a T cell receptor (TCR)-independent manner.
160 eading to increased resistance in a mutation-independent manner.
161 dation through the proteasome in a ubiquitin-independent manner.
162 ABA is a prosurvival factor for Mks in a Tpo-independent manner.
163 sed activation of the inflammasome, in a PKR-independent manner.
164 y Ulp1 destabilizes Smo in a phosphorylation independent manner.
165 tivity in a DNA binding-dependent and ligand-independent manner.
166 ives tumor initiation and growth in an Eiger-independent manner.
167 as found to influence aortic strain in a sex-independent manner.
168 ptors on glutamatergic neurons in an insulin independent manner.
169  in a glutaminolysis-dependent and autophagy-independent manner.
170 in both liver x receptor (LXR)-dependent and independent manners.
171  lineages, in both let-7-dependent and let-7-independent manners.
172 croptosis, in both RIPK1-dependent and RIPK1-independent manners.
173 cell death in both RIPK1-dependent and RIPK1-independent manners.
174 function in both inflammasome-dependent and -independent manners.
175 rotein pUL38 in both TSC2-dependent and TSC2-independent manners.
176 in in an inflammation-dependent, but antigen-independent, manner.
177 d3 in TGF-beta receptor-dependent, but SphK1-independent, manner.
178 at telomeres in a RAD52-dependent, but RAD51-independent, manner.
179  in Aim2-deficient mice in an IL-1beta/IL-18-independent manner after DNA vaccination.
180 lhG interacts with FliM/FliY in a nucleotide-independent manner and activates FliM/FliY to assemble w
181                  Hsp20 binds AC9 in a Yotiao-independent manner and deletion of AC9 decreases Hsp20-a
182  found that the binding occurred in a Ca(2+)-independent manner and did not involve the PCh-binding s
183 complexes with PAX3 and NKX2-1 in a sequence-independent manner and exacerbates their respective tran
184 illed >90% of the B. pseudomallei in a CPS I-independent manner and exhibited an antibacterial cytoki
185 n resistance in a hypoxia-inducible factor 1-independent manner and impaired insulin signaling in liv
186 tive target of mTORC2, in a SMAD2- and SMAD4-independent manner and increased bladder cancer cell mig
187 A2 promoted stem cell properties in a kinase-independent manner and increased Sox2 expression.
188 distal regions were resegregated in a ParABS-independent manner and instead likely rely on a physical
189  triggers effector functions in a diapedesis-independent manner and is inhibited by the processes of
190 at this DSP domain acts as a ligand in a RGD-independent manner and is involved in intracellular sign
191 single DNA molecular regulator in a sequence-independent manner and its applications in three-dimensi
192 ted after resistance exercise in a rapamycin-independent manner and may play a role in determining tr
193 so found that SPEN binds ERalpha in a ligand-independent manner and negatively regulates the transcri
194   IOS1 also associated with BAK1 in a ligand-independent manner and positively regulated FLS2-BAK1 co
195          Notably, menthol acted in a voltage-independent manner and reduced the mean open time of sin
196 this context, CD55 functions in a complement-independent manner and required lipid raft localization
197 curs in a type III secretion system (T3SS) 1-independent manner and results in restrained disruption
198 pts behavioral inhibition in a GRK3/arrestin-independent manner and suggests that KOR antagonists cou
199 GLI3 is sufficient to generate MNs in an SHH-independent manner and that temporal changes in exposure
200 tive chromatin in both an RNA-dependent and -independent manner and that this association is abolishe
201 d against pathogens and tumors in an antigen-independent manner and then undergo cell death.
202 n LPS challenge occurs in a protein kinase A-independent manner and, rather, is associated with inhib
203 reover, CLEC18 bind polysaccharide in Ca(2+)-independent manner, and amino acid residues Ser/Arg(339)
204 is cleaved off by PorU sortase in a sequence-independent manner, and anionic lipopolysaccharide (A-LP
205 dergo degranulation in an IgE-dependent and -independent manner, and can be readily cultured in vitro
206 -cAMP) acutely to activate PKA in a receptor-independent manner, and cardiac hemodynamic function and
207 owever represses its translation in an eIF4E-independent manner, and contributes to silencing of mRNA
208 7 transcriptional activity in an RNA-binding-independent manner, and controls expression of the endog
209 ia binding its receptor TMEM219, in an IGF-I-independent manner, and disrupted in vivo CoSC function
210 s regulated by type I IFN and IL-18 in a TCR-independent manner, and IFN-gamma secreting gammadelta T
211 igase RNF8 in a Piwi-interacting RNA (piRNA)-independent manner, and MIWI stabilization sequesters RN
212 c1, PI3K/AKT and MEK/ERK signaling in a PTEN-independent manner, and promoted cell and tumor viabilit
213 mic equilibrium on mitochondria in a fission-independent manner, and that fission factors such as act
214 cer liver micrometastases in a proliferation-independent manner, and these pathways can be targeted a
215 f nTh1 cells that express IFNgamma in a Tbet independent manner, and whose expansion can be enhanced
216  peptide revealed that it acts in a sequence-independent manner as an open-channel NMDAR antagonist a
217 tive activity and apoptosis in a caspase-3/9-independent manner, both in vitro and in vivo in a tumor
218 e when stimulated in a T cell receptor (TCR)-independent manner but failed to do so in TCR-dependent
219 o isoforms of the hKv7.4 channel in a Ca(2+)-independent manner but that only the long isoform (hKv7.
220 ARgamma transcriptional activity in a ligand-independent manner, but the mechanism for this effect wa
221 rmone-related protein (PTHrP)-dependent and -independent manner by activating transcriptional mediato
222  keratinocyte differentiation in an adhesion-independent manner by dampening Epidermal Growth Factor
223 , DN, and Tr1 Treg can also act in a contact-independent manner by elaborating soluble immunosuppress
224 el open probability in GluN2 subunit- and pH-independent manner by increasing the mean duration of cl
225 s SCs in culture in a cell type- and species-independent manner by inducing apoptosis.
226      In addition, UBR5 functions in a ligase-independent manner by prompting protein/protein interact
227 lar organization is modified in a brain size-independent manner by sex (relative expansion of total c
228 re unit-sized crRNAs are provided in a Cas6e-independent manner by transcription termination, the CRI
229 wth factor receptor (PDGFR) beta in a ligand-independent manner by transmembrane helix-helix interact
230  TSC1/TSC2/TBC1D7 protein complex and mTORC1-independent manner, contributing to intrinsic resistance
231 pu counteracts tetherin in a largely species-independent manner, degrading both the long and short is
232 OR binding affinity to Rag GTPases in an Akt-independent manner, demonstrating a previously undescrib
233 gnaling hyperactivation, albeit in GSK-3beta independent manner, differentiated colon cancer in claud
234 tream facilitates promoter melting in an ATP-independent manner, distinct from a DNA translocase acti
235 cine-rich repeat domain of NLRP3 in a kinase-independent manner downstream of the induction of mitoch
236 . coli fermentation can continue in a growth-independent manner during nitrogen limitation, while amm
237 acquire gut homing receptors in a largely RA-independent manner during their development in the bone
238                                Hence, in CDK-independent manner, endogenous p21 prevents a type of ge
239 onstrate that UTX, in a demethylase activity-independent manner, facilitates conversion of inactive e
240 age, binds double-stranded DNA in a sequence-independent manner, facilitates processing of damaged DN
241 occurring rapidly and in a protein synthesis-independent manner, followed by a second phase that is m
242 This system can be activated in a convertase-independent manner from intracellular stores of the comp
243 ecific binding site can take place in a path-independent manner given reasonable values of the free e
244  redistribute along the genome in a sequence-independent manner, giving rise to chromatin position ef
245 te Montipora white syndrome in a temperature-independent manner had similarly reduced virulence.
246 -alpha1, -2, and -8 were induced in an IFNAR-independent manner in cells infected at both virus conce
247 t lower virus concentrations and in an IFNAR-independent manner in cells infected at higher virus con
248 ) serum enhanced HAdV-5 transduction in a FX-independent manner in CHO-CAR and SKOV3-CAR cells (CHO o
249 or (SLPI) is regulated by the AR in a ligand-independent manner in CRPC cells and required for CRPC c
250 oallelically expressed in a parent of origin-independent manner in hematopoietic stem cells and early
251 ally, NPY and Y5R were upregulated in a BDNF-independent manner in NB cells under pro-apoptotic condi
252 ism of mTORC1 activation by ERK1/2 in an Akt-independent manner in oligodendrocytes.
253 ugh enhancers can function in an orientation-independent manner in reporter assays, in the native chr
254 nd TLS in a FANCD2 monoubiquitination and HR-independent manner in response to HU.
255 tes initial platelet activation in a contact-independent manner in the absence of Eph-ephrin ligation
256 1.7 kcal/mol in a largely sequence- and salt-independent manner, in quantitative agreement with our s
257 diA also promotes auto-aggregation in a BamA-independent manner, indicating that the exoprotein posse
258  FN trafficking in a transcription- and SMAD-independent manner, is a direct and rapid inducer of the
259 ately increased Ca(2+) in a protein kinase G-independent manner leading to microneme secretion.
260 eased expression of Ccl5 and Cxcl10 in a p53-independent manner, mediating increased infiltration of
261     Syk mediates bronchoconstriction in a NO-independent manner, presumably via rho kinase and p38 MA
262        Protons regulate TMEM16A in a voltage-independent manner, regardless of channel state (open or
263 ve splicing in either a signal-dependent or -independent manner remain enigmatic.
264 R/AR-V7 target genes in ligand dependent and independent manners respectively.
265 t Parkin affects mtDNA levels in a mitophagy-independent manner.SIGNIFICANCE STATEMENT Parkinson's di
266  virus encoding mitochondrial PB2, in a MAVS-independent manner, suggesting a role for PB2 within the
267  three isoforms bound to F-actin in a Ca(2+)-independent manner, suggesting that binding of only one
268 odulator of stomata development, in a ligand-independent manner, suggesting that ERECTA, SERKs, and T
269 LPS), which stimulates B cells in an antigen-independent manner, suggesting that rapamycin specifical
270  PTPalpha phosphorylation to occur in an Abl-independent manner, suggesting that SFK activity dominan
271           Activation is initiated in a Trem2-independent manner that involves downregulation of micro
272 ansgene expression in a hyaluronic acid-CD44 independent manner that is down-regulated by inhibitors
273  LEDGF/p75 interacts with SSRP1 in an hSpt16-independent manner that requires the PWWP domain of LEDG
274 se transitions in a nucleotide-dependent and independent manner, thereby adding another layer of regu
275 te the expression of PCH1 and PCHL in a phyB independent manner, thereby increasing the response to r
276 vation of this signaling cascade in a ligand-independent manner, thereby promoting arteriogenesis in
277 tions that shape-sensing occurs in a tension-independent manner through integrin beta3 signaling path
278 er, some transcripts are translated in a cap-independent manner through poorly understood mechanisms.
279 P12 increase hepcidin expression in a ligand-independent manner, through BMP-SMAD signaling.
280 protein kinase 2-TGF-beta-activated kinase 1-independent manner to activate the WNT signaling cascade
281 ciates with autosomes of germ cells in a DCC-independent manner to enrich H4K20me1 and trigger chromo
282 rs may operate in a homologous recombination-independent manner to maintain genomic integrity.
283 ient to sustain intrinsic signaling in a LIF-independent manner to promote ES cell pluripotency and s
284 heart disease pathogenesis, in a deacetylase-independent manner to regulate development of second hea
285 n both a chromatin-dependent and a chromatin-independent manner to regulate the INK4A and p53 pathway
286 omes remain highly dynamic-in a modification-independent manner-to control neuronal- and glial-specif
287 ulates muscle GLUT4 expression in an insulin-independent manner under conditions of insulin resistanc
288        NO also appears to function in a cGMP-independent manner, via S-nitrosation (SNO), a redox-bas
289 can move on 0.3% agarose media in a flagella-independent manner when experiencing the PhoP/PhoQ-induc
290  cell death in a caspase-1-, ASC-, and NLRP3-independent manner, whereas the presence of cholesterol
291  and forms two types of complexes in a metal-independent manner, which may explain the wide spectrum
292 ion sensitizes cells to ferroptosis in a p53-independent manner while ARF depletion induces NRF2 acti
293 lyzed by UBE2E family of E2 enzymes in an E3-independent manner while the conjugated-ubiquitin (Ub) i
294 pic objects to be described in a measurement-independent manner, while largely preserving a fully qua
295 d by membrane recruitment, in an orientation independent manner with no additional contributions prov
296 hing show that human FZD4 assembles-in a DVL-independent manner-with Galpha12/13 but not representati
297 uired for phosphorylation of STATs in a SMAD-independent manner within minutes of TGF-beta stimulatio
298 espan in an Hsp70 chaperone-dependent and CR-independent manner without increasing H2O2 scavenging or
299 genous PCR-generated sequences in a homology-independent manner without loss of additional nucleotide
300 nts that induce damage in a cell cycle stage-independent manner, zebularine induces damage specifical

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