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1 nical phenotypes (drug side effects and drug indications).
2 conventional needles for any lumbar puncture indication.
3 patients undergoing routine RHC for clinical indication.
4 may be used as a predictive factor for ASCT indication.
5 ' mean age was significantly higher in every indication.
6 may be more effective than morphine for this indication.
7 d States have received TAVR for an off-label indication.
8 rivaroxaban-treated patients without a renal indication.
9 ider diagnosing the enrollee than by medical indication.
10 ing 27-gauge PPV for a vitreoretinal surgery indication.
11 ovides a strong evidence for the theoretical indication.
12 n patients who received TAVR for an on-label indication.
13 ific clinical situations might become future indications.
14 interactions with pharmacological action and indications.
15 of hematologic malignancies and solid tumor indications.
16 ts are increasingly used for a wide range of indications.
17 already used in humans for other therapeutic indications.
18 some B-cell disorders while restricting OBZ indications.
19 ent inhibitor of FGFR1-4 for use in oncology indications.
20 llous keratopathy (PBK), infection and other indications.
21 ntial drug repositioning from other clinical indications.
22 ecular therapeutics for a variety of disease indications.
23 even for patients who appear to meet labeled indications.
24 to 2013, especially among men without clear indications.
25 y in routine clinical use for other clinical indications.
26 r further development for clinical cognition indications.
27 al responses in patients with multiple tumor indications.
28 obal modeling rather than individual country indications.
29 e application of approved drugs to treat new indications.
30 efficacy by combining bnAbs for therapeutic indications.
31 en, reflecting known differences between the indications.
32 d with a toxicity profile similar to labeled indications.
33 application in oral drug delivery in various indications.
34 ncer patients who do not have cardiovascular indications.
35 he theranostic principle into other oncology indications.
36 ent SLK and those who received SLK for other indications.
37 vasculitis than in those referred for other indications.
38 scans were obtained for medical necessities (indications 1-11), and in 5.6% of the scans (30/531) whe
40 nted accelerated approval to 22 drugs for 24 indications (19 for indications involving cancer treatme
42 pleted and demonstrated efficacy in 10 of 24 indications (42%) on the basis of trials that evaluated
44 ne oxygenation (87% veno-venous) for medical indications (78% acute respiratory distress syndrome).
47 and investigated factors associated with the indication and failure of a medication step-down treatme
48 T-guided management decisions, stratified by indication and type of guidance (confirmatory vs. influe
50 sing a modified classification system for PK indications and analyzed via multivariate regression.
51 ce standards, and drafted recommendations on indications and duration for electrocardiographic monito
52 phthalmologic monitoring, outlines treatment indications and forthcoming biologic therapy, and discus
53 lated PrEP uptake following the prescription indications and HIV/STI screening recommendations in the
55 icacy of (68)Ga-DOTATOC for several distinct indications and is intended to support approval of this
56 vascular medicines in China, its therapeutic indications and mechanisms remain partially defined.
57 inal graft failure with special reference to indications and outcomes of allograft enterectomy and th
58 uss several predictions for both therapeutic indications and side-effects through the published liter
59 small proportion of patients, due to contra-indications and the costs associated with establishing t
61 tient preferences" (a type of confounding by indication) and has implications for assessments of trea
64 tion exposure according to facility for this indication, and to establish a current average radiation
65 of ongoing trials, new approaches, emerging indications, and a potential clinical algorithm incorpor
66 Drug Administration approvals, new off-label indications, and new competitors did not influence the a
67 estion the value of this operation for these indications, and this should be communicated to patients
72 resence of donor-specific antibodies, biopsy indication, Banff ct, t, ah and cg scores, and retained
73 nal transplant patients with surveillance or indication biopsies were assayed for 133 unique metaboli
74 ll uses can be categorised by population and indication, both of which influence the balance between
75 substantial among patients without clinical indications but is low when patients report that their s
79 should have a comprehensive knowledge of the indications, contraindications, risks, benefits, and out
81 , and the illumination patterns of the sound-indication devices allow us to discriminate multiple sou
82 ue that utilizes multiple, distributed sound-indication devices and a miniature LED backpack to visua
83 aging procedure and interpretation, clinical indications, diagnostic potential, and impact on treatme
84 e review of evidence and recommendations for indications, duration, and implementation of continuous
85 ents if they had continuous EEG for clinical indications, excluding epilepsy monitoring unit admissio
86 sing records of patients' biodata, MRI date, indication, findings and scan time, sources of referral,
88 associated with albumin use were appropriate indication for albumin use (odds ratio, 65.220; 95% CI,
90 gh prevalence in women both with and without indication for anorectal testing, along with a substanti
92 h no significant difference according to the indication for anticoagulation (P for heterogeneity = .4
94 human and mouse O4(+) cells, but there is no indication for BDE-99 interfering with cellular TH signa
95 lities in 35 of 193 patients (18.1%) with an indication for brain imaging, compared with only 2 of 35
98 early-stage breast cancer who had a definite indication for chemotherapy, any nodal status, any hormo
99 nger duration of disease at the time of IRA, indication for colectomy and having received immunomodul
100 5682 individuals older than 18 years with an indication for coronary stenting were enrolled, and 1164
101 Among the 13,392 patients with no renal indication for dose reduction, 13.3% were potentially un
103 cent revascularization, and patients with an indication for dual antiplatelet therapy were excluded.
104 within 3 cm of the sapheno-femoral junction, indication for full-dose anticoagulation therapy, and su
105 CE Dilated cardiomyopathy is the most common indication for heart transplantation worldwide, and coxs
106 s of head CT in patients with CAM without an indication for imaging is limited and has no impact in c
109 Hepatitis C virus (HCV) remains the leading indication for liver transplant in much of the world and
111 lation and is expected to become the leading indication for liver transplantation in the next decade.
116 enced patients (HCV genotypes 1-6) while the indication for NS5A inhibitor- naive patients was limite
122 ina or an acute coronary syndrome who had an indication for physiologically guided assessment of coro
124 upper gastrointestinal bleeding is a leading indication for red blood cell (RBC) transfusion worldwid
125 ortant single negative predictive factor for indication for step-down treatment (Odds ratio; 0.19).
126 in 227 patients (73.2%), and the most common indication for surgery was aortic stenosis (n = 225 [72.
130 duced endothelial NO production is a further indication for the roles of ROS and NO in atherosclerosi
134 used for significant changes in a device or indication for use and always requires clinical data).
135 9m)Tc-NaTcO4) was performed in patients with indications for a thyroid scan to demonstrate the clinic
136 ivity, regulatory, pharmacologic actions and indications for active pharmaceutical ingredients approv
137 ration of SSRS has fundamentally changed the indications for and type of surgery performed for metast
139 targets of antiplatelet agents, and clinical indications for antiplatelet therapy before focusing on
140 althcare, the potential gains from expanding indications for cardioprotective medications will not be
141 ing ontologies, the inclusion of targets and indications for clinical candidates, addition of metabol
144 specified imaging protocols, well-documented indications for CT, training of technicians, and quality
151 ere are limited data about the incidence and indications for late allograft pancreatectomy while on c
155 take a clinical approach and focus on common indications for omega-3 polyunsaturated fatty acid suppl
156 s of hospital admission if they had no clear indications for or contraindications to oxygen treatment
157 ient VTE diagnosis only, patients with other indications for oral anticoagulation treatment, patients
158 e national trends in other previously common indications for PAC placement, PAC use overall, or outco
161 was reduced after we adjusted for potential indications for PPI use, including history of peptic ulc
163 Implantable cardioverter-defibrillator (ICD) indications for primary prevention in Brugada syndrome (
164 ilability of effective pharmacotherapies and indications for some tailored pharmacotherapies for Afri
166 e surgical management of NEC, beginning with indications for surgery and following with a section on
167 n obstruction is mostly detected prenatally; indications for surgery have been refined with evidence,
168 we review the established literature on the indications for surgery in asymptomatic pHPT and discuss
170 approaches for degrading plant biomass, and indications for the genetic basis of stress response.
171 nd medullary thyroid cancers represent novel indications for the in vivo radiopeptide targeting of ss
174 d, as well as opportunities for expansion of indications for use of approved targeted therapies.
176 ng on long-term use of PPIs for three common indications: gastroesophageal reflux disease (GERD), Bar
177 Elective lead extraction for noninfectious indications had similar long-term survival to that for c
179 bundant information on drug side effects and indications has been recorded over time through extensiv
180 to 13.14; p < 0.01) and secondary prevention indication (hazard ratio: 6.85; 95% confidence interval:
181 it assessment, auto-CPAP titration (for CPAP indication), health-related quality-of-life questionnair
182 gical patients with an acute and correctable indication; however, survival decreases significantly wi
184 s first part of a 2-part review, we describe indications, implant-related complications, basic functi
187 corneal dystrophy was the fourth most common indication in North America (12.9%) and Europe (10.2%) a
192 available, for patients with other clinical indications, including patients with diabetes mellitus a
194 results linked to Medicare claims by imaging indication (initial staging [IS]; detection of suspected
195 ncluding general surgeons, to understand the indications, interpretations, and costs associated with
196 roval to 22 drugs for 24 indications (19 for indications involving cancer treatment) between 2009 and
197 ication of riociguat in other cardiovascular indications is limited by its short half-life, necessita
198 in, although not currently approved for this indication, is frequently used for the treatment of VRE-
201 risk, whereas dose reductions without a firm indication may decrease the effectiveness of stroke prev
202 r reintervention for aortic valve structural indications, measured using aortic valve mean gradient,
203 The benefits of PPI therapy for appropriate indications need to be considered, along with the likeli
204 hese findings represent the first functional indication of a direct link between an NDM-linked activa
206 ralgesia against inflammatory pain, the main indication of acetaminophen, and the precise site of the
210 educed risk of CVD or death but also gave no indication of confounding by disability, comorbidities o
211 tise is strongly recommended and an extended indication of curative treatment by HSCT should be consi
213 clusively via their shared location, with no indication of direct binding between color and orientati
214 ions occurring in 2014-2016, and could be an indication of future conditions under projected climate
215 seafloor to provide a realistic and relevant indication of how benthic communities may change under f
216 This approach also provides a quantitative indication of how likely some regulatory interactions mi
218 ions, low-density populations had a stronger indication of IBD than medium- to high-density populatio
221 dominantly microglia), can be measured as an indication of neuroinflammation in vivo using positron e
223 roxymethylfurfural (HMF) in honey provide an indication of overheating under inappropriate storage co
225 thermore, the carrier density was used as an indication of porosity to correlate with drug aerosoliza
227 trials investigating agents with an approved indication of reperfusion therapy in STEMI (streptokinas
230 tionship between scratching and stress as an indication of the animal's stress state, and thus scratc
232 model returns a predicted solubility and an indication of the features which deviate most from avera
233 examining the nonproductive repertoire as an indication of the immediate product of the rearrangement
234 f conversion of MitoA to MitoN thus gives an indication of the levels of mitochondrial H2S in vivo Bo
235 casein hydration and dispersion and gives an indication of the levels of soluble calcium and protein
236 rate are two measures frequently used as an indication of the physiological performance of individua
238 upon A.C protonation, providing experimental indication of the preferential localization of more high
239 ar relationship is usually interpreted as an indication of the presence of one or more species that c
242 propensity score to minimize confounding by indication of treatment and capacity to achieve SVR.
245 ed phenotype persisted in elderly TG with no indications of cardiac pathology or premature death.
249 ntext of adaptation experiments in reaching, indications of long-term motor memories were also demons
250 rearing style was associated with heightened indications of mental burden, depressiveness, and sense
251 findings are useful since provide MRI-based indications of possible subtending connectivity and, if
254 ents that require flexible endoscopy for the indications of weight loss or treatment of glucose intol
256 primate models already approved for another indication or for which there was existing safety data w
257 Compared with standard options for this indication, our results show that nivolumab is effective
258 med; yet, there is often confusion regarding indications, outcomes, and how to identify those patient
259 erefore it should not be prescribed for this indication outside of research studies with explicit par
261 ) has emerged as a promising target for both indications, raising demand for new chemotypes of KOR an
262 ted for age, sex, race/ethnicity, initial TT indication, reinsertion of TT, adenoidectomy, and number
263 Details of each session were scored for indication-related details (informative or not) and asse
265 aggregation of st-AuNPs, which produces the indication signal, is achieved very differently than in
267 on data by mathematical deconvolution, using indication-specific and cell type-specific reference gen
268 lar diagnostics in hematologic malignancies: indication-specific single gene assays, gene panel assay
272 atients receiving VTE prophylaxis or with an indication that prophylaxis was unnecessary increased fr
273 )P NMR spectra and DFT investigation provide indication that the deprotonated guanidine involved in s
276 over drugs that are routinely used for other indications that could be effective in treating various
277 cal benefit had not yet been confirmed for 8 indications that had been initially approved 5 or more y
279 ILEI beta-beta-alpha fold confirmed previous indications that the FAM3C proteins do not form classica
280 ion is strongly suggested, because there are indications that, before flooding, relative head size di
281 urrently in clinical trials for a variety of indications, the outcomes of which will present the oppo
282 t eliminate the potential for confounding by indication, these findings do not support early tracheal
283 e of imidazoquinoline TLR agonists for other indications, these studies identify multiple adjuvant fo
285 lly highlight the presence of feedback as an indication to combine chemotherapy with approaches that
286 portal flow modulation protocol with defined indications to better define the effects of these interv
288 th of this material has limited its clinical indications to structurally less demanding applications,
289 e of aspirin sensitivity manifestation, with indications to undergo coronary angiography with intent
290 ong 437 patients from 16 centers, a shift in indications toward colorectal liver metastases from 53%
291 Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Da
294 We seek to provide context as to why a broad indication was given for NS5A inhibitor-experienced pati
298 ratory viral tests and suggest some clinical indications where viral testing may play an important ro
299 ance metrics varied widely across diagnostic indications, with cancer detection rate (64.5 per 1000)
300 Is also hold therapeutic potential for other indications, with four candidates under clinical develop
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