ライフサイエンスコーパス: indiscriminately

1 h targets both mammalian and bacterial cells indiscriminately).

2 atible as MAT kills sterile and 'wild' males indiscriminately.

3 ess the correct AG, but can attack other AGs indiscriminately.

4 lock all receptor-coupled signaling pathways indiscriminately.

5 erneuronal synaptic and autaptic connections indiscriminately.

6 s display pervasive fear memories, expressed indiscriminately.

7 if the background levels are allowed to rise indiscriminately.

8 etic fluorescent indicator dyes label tissue indiscriminately.

9 ly adverse impact that IPM carries when used indiscriminately.

10 and optimal 5' exon and lariat intermediates indiscriminately.

11 successful than mediator-specific drugs used indiscriminately.

12 that the mid-14th-century Black Death killed indiscriminately.

13 initiate replication seem to bind chromatin indiscriminately.

14 g prophase I and instead seemed to associate indiscriminately.

15 clinically important antimicrobials are used indiscriminately.

16 ment for breast cancer, aromatase inhibitors indiscriminately abolish estrogen synthesis in all tissu

17 In contrast, radiation indiscriminately activated all ErbB species with the act

18 Indeed, most current treatments indiscriminately affect both the autoreactive T cells an

19 ression by naive T cells, which is activated indiscriminately after parasitism.

20 quo therapeutic strategies that target TAMs indiscriminately and in favor of strategies that specifi

21 germ cells migrate into gonads of either sex indiscriminately and may be functional even across a spe

22 tance, solubility or propensity to aggregate indiscriminately, and is thus dependent solely on the ov

23 hat occur when toxicology tests are obtained indiscriminately, are misapplied, or are misunderstood a

24 on by binding inside the ribosome tunnel and indiscriminately arresting the elongation of every nasce

25 It is not known whether they act indiscriminately as general modulators of transcription

26 When coexpressed, TLR4 indiscriminately associates in the endoplasmic reticulum

27 ein, and whose disruption permits Mfd to act indiscriminately at transcription complexes that lack th

28 ability of BLyS to increase B cell survival indiscriminately, at either a resting or activated state

29 Sexually explicit material is now indiscriminately available to youth, and studies have li

30 h an array of nonspecific nucleases degrades indiscriminately based on target size or ribosome protec

31 -box on the P4Halpha(I) promoter appeared to indiscriminately bind with either USF1 or USF2, with a s

32 sol of CCs do enter the translocation stream indiscriminately but are also subject to distributive fo

33 Red/green cones were coupled indiscriminately but blue cones were rarely connected wi

34 natural products that bind to these proteins indiscriminately but with nanomolar affinity.

35 C57 females used this strategy indiscriminately, but DBA females sampled as a function

36 nitially reached toward the baited container indiscriminately, but gradually and with the aid of colo

37 mentation of the mutated proteins is blocked indiscriminately by nucleotides.

38 Although it appeared that GN adsorbed PAHs indiscriminately compared to MWCNTs, the subsequent bioa

39 r highly divergent axons, inhibitory neurons indiscriminately contact most neighbouring pyramidal cel

40 dules bind in general with high affinity but indiscriminately, cross-species binding is rare.

41 to a cationic cell-penetrating peptide, were indiscriminately cytotoxic independently of p53 status.

42 clinically deployed today are designed to be indiscriminately cytotoxic, however, achieving selective

43 A noninvasive technology that indiscriminately detects tumor tissue in the brain could

44 imarily disease-causing bacteria rather than indiscriminately eliminating natural gut flora.

45 Current therapeutics indiscriminately enhance the activity of the endogenous

46 In 8-year-olds, these regions were recruited indiscriminately for detail recollection and item recogn

47 ically, young children engaged RLPFC and IPL indiscriminately for first-order and second-order relati

48 timicrobial agents continue to be prescribed indiscriminately for upper respiratory infections.

49 ese retinal ganglion cells draw their inputs indiscriminately from a coarse-grained mosaic of red and

50 we provide evidence that Srs2 removes Rad51 indiscriminately from DNA, while the Rad52 protein coord

51 ls cannot do this because they receive input indiscriminately from M and L cones.

52 the TVB-NRG1 bridge protein receives inputs indiscriminately from S1 input sources.

53 lls the expressed H-type alpha1,2FT does not indiscriminately fucosylate terminal galactosyl residues

54 rm competition, Peromyscus polionotus, sperm indiscriminately group with unrelated conspecific sperm.

55 sh functional connections with L and M cones indiscriminately, implying that the cone-selective circu

56 ore, the rats with lesions not only searched indiscriminately in all four quadrants, they also did no

57 lgi merozoites invade monkey red blood cells indiscriminately in vitro, in humans, they are restricte

58 opose that the Pro-253 --> Arg mutation will indiscriminately increase the affinity of FGFR2 toward a

59 posed to NGF via bath perfusion, rapidly and indiscriminately increased the rate of spontaneous firin

60 rus (VV) and canarypox virus (ALVAC), do not indiscriminately infect all cell types of the primary hu

61 We propose that EBV indiscriminately infects B cells in mucosal lymphoid tis

62 reduced the amount of the large subunit and indiscriminately inhibited mitochondrial translation.

63 egradation of newly synthesized APOBEC3G but indiscriminately inhibits encapsidation of "old" and "ne

64 , we demonstrate that the protein integrates indiscriminately into virtually any biological membrane,

65 unologically naive, that the epidemic killed indiscriminately, irrespective of age, sex, or frailty.

66 nt over current chemotherapeutic agents that indiscriminately kill proliferating cells.

67 neurotropic flaviviruses, as West Nile virus indiscriminately killed both tumor and normal neural cel

68 y assayed by formaldehyde application, which indiscriminately modifies proteins and is presumed to ca

69 The accumulation of MG indiscriminately modifies proteins, including important

70 We show that the PAFc is indiscriminately necessary for the proliferation of AML

71 results suggest that miRNAs are incorporated indiscriminately of their sequence into Ago1 through Ago

72 Clinicians frequently but at times indiscriminately perform computed tomography scans for c

73 A) polymerases, which act in the nucleus and indiscriminately polyadenylate all mRNA, Cid13 is a cyto

74 Depletion of Ca2+ indiscriminately prevented the nuclear import of macromo

75 r key components of innate immunity, did not indiscriminately promote intracellular infections (Mycob

76 nti-tubulins, auristatins and maytansinoids, indiscriminately radiosensitize tumour cells, conjugatin

77 nearby area and target excitatory neighbors indiscriminately, raising the issue of how neuronal acti

78 in widespread use for killing microorganisms indiscriminately, rapidly, and by nonspecific action.

79 and other animals do not use social learning indiscriminately, rather, natural selection has favoured

80 A second-site suppressor, ExbB(A39E), indiscriminately reactivated the majority of H20 substit

81 Acutely infected brains and spinal cords indiscriminately recruit a homogeneous population of ear

82 nd external tufted cells, and, in turn, they indiscriminately release GABA onto principal neurons.

83 le's choices (regardless of confidence) were indiscriminately represented across vmPFC.

84 l cells get mixed L and M cone input, likely indiscriminately sampled from the randomly arranged cone

85 d specificity of this complex, and that CD14 indiscriminately serves to deliver the ligand to TLR4.

86 f emotionally withdrawn (inhibited type) and indiscriminately social (disinhibited type) reactive att

87 Although high concentrations of exogenous NO indiscriminately suppress the proliferation and differen

88 ver, how such patterns, which are thought to indiscriminately synchronize nearby cells, could provide

89 rase inhibitors display limited specificity, indiscriminately targeting all enzymes that use AdoMet.

90 display limited specificity and selectivity, indiscriminately targeting many methyltransferase enzyme

91 gnaling functions of senescence suggest that indiscriminately targeting senescent cells or modulating

92 ts suggest that the Black Death did not kill indiscriminately-that it was, in fact, selective with re

93 ulants or caged neurotransmitters, which act indiscriminately throughout the illuminated volume, chAR

94 uence, these data suggest A1 generally binds indiscriminately to all available pre-mRNA sequences.

95 A universal base must pair indiscriminately to each of the canonical bases with lit

96 anscriptome in comparison with TAMs isolated indiscriminately to function using established macrophag

97 pivotal role in enabling the peptide to bind indiscriminately to mu- and delta-receptors.

98 In contrast, core neurons responded indiscriminately to presentations of the SD tone or the

99 sistent with the propensity of S-DNA to bind indiscriminately to proteins.

100 inding to 5'SSs by binding cooperatively and indiscriminately to the pre-mRNA.

101 (VNO) displayed male-typical sexual behavior indiscriminately toward female and male conspecifics.

102 Indeed, a constitutively active NICD indiscriminately up-regulates expression of both HERP1 a

103 bacteriophage T7 were grown to fix mutations indiscriminately, using a combination of population bott

104 lines results from males courting both sexes indiscriminately, whereas in other lines this phenotype

105 HV is able to infect a variety of cell types indiscriminately, while in healthy latent carriers KSHV

106 d tertiary structure and binds RNA sequences indiscriminately with a dissociation constant (Kd) of ap

107 a-Globin pre-mRNA (exons 1 and 2) is spliced indiscriminately with either SR protein.

108 nd that MT-projecting cells were distributed indiscriminately with respect to cytochrome oxidase comp

109 work, we explore the use of silanes to react indiscriminately with RNA such that the primary factor g

110 ed state is essential because CBP2 assembles indiscriminately with the bI5 RNA in any folding state t

111 L lacking the CAAX motif can still associate indiscriminately with the plasma membrane and retains it

112 s and, when overexpressed, Helios associates indiscriminately with the various Ikaros isoforms.

113 able exceptions, have come to reside largely indiscriminately within the several agr groups.