ライフサイエンスコーパス: individual variation

1 with a mainly genetic contribution to inter-individual variation.

2 promoters to reveal the full extent of inter-individual variation.

3 verage genome that provide a source of inter-individual variation.

4 hanisms that simultaneously permit and limit individual variation.

5 tal blood fatty acids, with DHA showing more individual variation.

6 und the interpretation of the observed inter-individual variation.

7 higher inter-individual compared with intra-individual variation.

8 nt SNPs are associated with odorant-specific individual variation.

9 reas of loss or gain, there was considerable individual variation.

10 to assess because of large amounts of intra-individual variation.

11 ne expression but also epigenetics and inter-individual variation.

12 d to the subsequent observation of low inter-individual variation.

13 well as when we looked at generic aspects of individual variation.

14 omputational model that can account for such individual variations.

15 ain as being responsible for the majority of individual variation across the normal population.

16 PCOs cannot account for individual variation among patients and cannot be consid

17 PCOs cannot account for individual variation among patients and cannot be consid

18 PCOs cannot account for individual variation among patients, and cannot be consi

19 PCOs cannot account for individual variation among patients, and cannot be consi

20 ze that guidelines cannot always account for individual variation among patients.

21 ze that guidelines cannot always account for individual variation among patients.

22 ze that guidelines cannot always account for individual variation among patients.

23 aniasis guidelines cannot always account for individual variation among patients.

24 iation cannot be ascribed to inter- or intra-individual variations among the observers, and points to

25 ematic framework to dissect inter- and intra-individual variation and build predictive models of post

26 e models in one framework and illustrate how individual variation and correlations in development can

27 to stratify patient care, the complexity of individual variation and covert actions of genetic modif

28 is question, we cataloged both individual-to-individual variation and differences between homologous

29 and a more variable one, possibly reflecting individual variation and medication use.

30 ), while the lumenal microbiota showed inter-individual variation and obligate anaerobe enrichment (e

31 vity maps display a delicate balance between individual variation and stereotypy, suggesting the exis

32 When fully accounting for individual variation and the full spectrum of neuro-opht

33 n-individual phenotypic plasticity and among-individual variation and to test alternative hypotheses

34 ortant questions around the normal limits of individual variation and whether individuals may be pred

35 In these two populations, between-individual variation and within-clutch consistency in eg

36 induction, which may contribute to the large individual variations and inducibility of CYP2B6 in huma

37 mplications of these findings for evolution, individual variation, and human bonding.

38 ire us to better account for habitat-derived individual variation, and to do so for the sexes appropr

39 emotion and stress processing, the bases of individual variation are less well understood.

40 How inter-individual variations are manifested in the functional b

41 In addition, individual variation can exacerbate the effects of demog

42 In this context of natural behaviors, individual variation can further inform about the factor

43 ons show many alternative outcomes and great individual variation during normal aging.

44 Gains in VO2 max demonstrate large inter-individual variation even in response to standardized ex

45 We asked whether similar individual variation exists for contextual cues associat

46 to be reasonably attributed to the amount of individual variation expected among con-specifics.

47 Joint and individual variation explained (JIVE) is a tool for expl

48 has been reported to show significant inter-individual variation from the effects of seven common su

49 A pathology was associated with substantial individual variation; however, within this group progran

50 Despite cultural and individual variation, humans are a judgmental bunch.

51 Individual variation in a specific type of mutation, unc

52 The procedure has significant value to study individual variation in acquisition of conditioned respo

53 e found a new metric of condition reflecting individual variation in acquisition, assimilation and/or

54 Trait social anxiety is associated with individual variation in affective responding, even in re

55 eared on an ad lib diet exhibited consistent individual variation in aggression and web weight only.

56 venly distributed across the population, and individual variation in altruistic tendencies may be gen

57 eveal an unexpected degree of complexity and individual variation in an invertebrate neural circuit,

58 Individual variation in antidepressant treatment outcome

59 We investigated whether the individual variation in antiviral response at birth dete

60 ns is possible where there is strong between-individual variation in appearance between conspicuous,

61 w studies have examined quantitative between-individual variation in AS within a cell or tissue type,

62 However, the role of individual variation in behavior to facilitate the persi

63 etic and environmental factors contribute to individual variation in behavioral responses to these cu

64 related to social rank, and thus for shaping individual variation in behaviour and social structure.

65 The amount of individual variation in behaviour and web structure vari

66 erogeneous environment might promote between-individual variation in behavioural plasticity.

67 s have revealed a relationship between inter-individual variation in blood pressure and the single nu

68 nd environmental factors interact to produce individual variation in body mass and accounting for thi

69 r DNA-methylation profiles account for inter-individual variation in body mass index (BMI) and height

70 udy, we present an analysis of the effect of individual variation in body mass on the temporal dynami

71 we show that the models explicitly including individual variation in body mass predict group dynamics

72 Individual variation in both survival and reproduction h

73 However, a large inter-individual variation in BZ sensitivity occurs in the hum

74 cilitate subsequent studies to explain inter-individual variation in cardiometabolic disease.

75 udied extensively, but the genetic basis for individual variation in CHC composition is largely unkno

76 bolism and represent mechanistic targets for individual variation in CHC composition.

77 milies, in which polymorphisms contribute to individual variation in chemosensation.

78 sual attention significantly associated with individual variation in childhood surgency and behaviora

79 Here, I review recent studies focused on individual variation in chromatin, and outline how epige

80 r CIITA and complement this by mapping inter-individual variation in CIITA expression as a quantitati

81 raits in mammals, but the factors underlying individual variation in circulating T levels are poorly

82 Inter-individual variation in clearance of methotrexate result

83 ness for apoptosis ("priming") might explain individual variation in clinical behavior.

84 the role that genetic factors might play in individual variation in cognitive abilities in nonhuman

85 ts support a unique role of the right SFG in individual variation in cognitive control.

86 ts and its relationship to cognitive effort, individual variation in cognitive performance, and fatig

87 s, but the evolutionary processes that shape individual variation in cognitive traits remain elusive

88 This variability has been shown to underlie individual variation in color matching behavior.

89 ely-viewed image of a dress elicits striking individual variation in colour perception.

90 At a given location, there was considerable individual variation in cone photoreceptor packing densi

91 Individual variation in CYP3A4 may play a role in breast

92 sm at -1082 of the promoter region linked to individual variation in cytokine inducibility has been s

93 icrobial communities may contribute to inter-individual variation in cytokine responses to microbial

94 The between-individual variation in daily physical activity and sede

95 nd immunological hypotheses explaining inter-individual variation in dengue viral load.

96 The common variants explain ~4% of inter-individual variation in disease risk and no more than 13

97 sal strategies have received much attention, individual variation in dispersal decisions and its fitn

98 ce of environmental heterogeneity or between-individual variation in dispersal phenotypes, two condit

99 ng an individual's food intake and assessing individual variation in disposition, bioavailability, an

100 s and genomic regions characterized by inter-individual variation in DNA hydroxymethylation.

101 amilies, to establish a catalogue of between-individual variation in DNA methylation.

102 or instance, a major factor underlying inter-individual variation in drug effects is variation in met

103 Individual variation in drug metabolism is a major cause

104 regions such as the hippocampus, may explain individual variation in estradiol effects on behavior.

105 e [29, 32-35] and whose genetic ancestry has individual variation in European and continental African

106 Genetic factors that influence individual variation in extraversion and neuroticism app

107 Individual variation in fetal hemoglobin (HbF, alpha(2)g

108 factors include epiretinal membranes, edema, individual variation in field-to-disc mapping, and the l

109 etime reproductive success but such realized individual variation in fitness components need not refl

110 The role of habitat use in generating individual variation in fitness has rarely been examined

111 dual life histories; and revealed consistent individual variation in foraging patterns, refuge use an

112 We found extensive individual variation in gene expression and cellular res

113 Individual variation in gene expression is important for

114 The range of inter-individual variation in gene expression of the in vitro

115 Individual variation in germline and expressed B-cell im

116 basis of type 2 diabetes (T2D) and the inter-individual variation in glycemic traits, including level

117 orts as well as the existence of substantial individual variation in growth trajectories after accoun

118 These data also suggest that individual variation in GSTP levels may be a factor in c

119 ata from fecal samples to characterize inter-individual variation in gut bacterial species.

120 ut provide new information for understanding individual variation in hemostasis pathways.

121 It has been shown that inter-individual variation in host response to porcine reprodu

122 Much of this inter-individual variation in human sociality remains unexplai

123 enes and genetic mechanisms underlying inter-individual variation in human traits, as well as support

124 vidence of significant heritability in inter-individual variation in IL6 gene expression but the gene

125 and statistical analysis of the influence of individual variation in infectiousness on disease emerge

126 n estimates of R(0) can obscure considerable individual variation in infectiousness, as highlighted d

127 ketamine-induced effects, although the high individual variation in ketamine response requires furth

128 be crucial to determine the extent to which individual variation in key functional attributes is gen

129 For instance, individual variation in lateral prefrontal cortex functi

130 sal path modeling analyses demonstrated that individual variation in left HG/STG morphology affected

131 Furthermore, we found that individual variation in levels of aversive pruning was a

132 Quantifying among-individual variation in life-history strategies, and ass

133 osophila melanogaster displays individual-to-individual variation in locomotor behaviors.

134 We examined individual variation in metabolic flexibility in respons

135 A recent article examines the extent of individual variation in microbial identities and how thi

136 s of reinforcement learning and suggest that individual variation in midbrain D3 receptors influences

137 t and/or indirect mechanisms, but imply that individual variation in migratory strategy and variation

138 ymorphism of three hot L1s and the extent of individual variation in mobilization capability of their

139 However, natural selection acting on wide individual variation in molt phenology might enable evol

140 evel averages promulgates neglect of between-individual variation in movement, potentially hindering

141 Inter-individual variation in MRS-measured GABA levels have be

142 Notably, the inter-individual variation in mutation rate and spectra are lo

143 ecular mechanism for mediating individual-to-individual variation in neuronal physiology and behavior

144 p between the genetic factors that influence individual variation in neuroticism and those that incre

145 p between the genetic factors that influence individual variation in neuroticism and those that incre

146 Epigenetics also contributes to individual variation in normal biology and in disease st

147 in insights into the genetic determinants of individual variation in odorant recognition, we measured

148 of odorant receptor genes can contribute to individual variation in olfactory behavior and give rise

149 Thus, individual variation in oxytocin receptor expression in

150 Women in the study had larger within-individual variation in partner ages compared to men.

151 articularly in populations with large within-individual variation in partner ages.

152 Inter-individual variation in patterns of DNA methylation at b

153 Individual variation in peak absorbance is large and ran

154 Individual variation in peak reproductive effort thus ha

155 Although there was individual variation in peptide reactivity, Ins1 B5-14 a

156 Despite significant inter-individual variation in pharmacokinetic parameters, conc

157 There is wide individual variation in pharmacokinetics, and little is

158 uantitative trait loci (QTLs) that influence individual variation in phenotypic traits related to bas

159 ement of emotional appraisal circuits drives individual variation in placebo analgesia, rather than e

160 The ecological consequences of inter-individual variation in plant volatile emissions remain

161 ns frequently explain only part of the inter-individual variation in populations.

162 Here, we examine factors responsible for individual variation in PPC frequency within a single wi

163 ealing with both information uncertainty and individual variation in preferences.

164 However, the neural bases underlying individual variation in proactive control of impulsive r

165 ulations also differed in the level of among-individual variation in reaction norm intercept, but we

166 intercept, but we found no evidence of among-individual variation in reaction norm slope.

167 , but little is known of the factors causing individual variation in reproductive ageing rates.

168 abilities with advancing age, indicative of individual variation in resilience to pathology.

169 anxiolytic peptide and help to explain inter-individual variation in resiliency to stress, a risk fac

170 Individual variation in response and duration of anti-va

171 This study evaluated the hypothesis that individual variation in response to estrogen levels cont

172 derstanding of how these contribute to inter-individual variation in response to infection.

173 The results suggest that individual variation in resting-state brain dynamics off

174 Considerable between-individual variation in retinal ganglion cell (RGC) dens

175 These data suggest that individual variation in retrotransposition potential mak

176 Individual variation in self-reported mood awareness was

177 The data reveal individual variation in sensitivity to reproduction and

178 Underlying mechanisms of individual variation in severity of influenza infection

179 sexually dimorphic traits (e.g., ornaments), individual variation in sexually selected traits often e

180 e a principal component analysis to describe individual variation in six feeding parameters and exami

181 Individual variation in social behavior seems ubiquitous

182 en made in understanding the neural bases of individual variation in social decision-making.

183 Individual variation in social phenotype was linked to t

184 models of culture: members of a species show individual variation in song and geographically separate

185 Consideration of consistent individual variation in space-use will facilitate mechan

186 tiple patient subgroups, there is wide inter-individual variation in statin efficacy, in terms of bot

187 the context of a model, to better understand individual variation in structure versus function.

188 ocial status in primates might be related to individual variation in subcortical brain regions implic

189 ternatives, and vmPFC effect sizes predicted individual variation in suboptimal decision-making in th

190 Inter-individual variation in survival stems from variation in

191 ly conserved candidate genes associated with individual variation in susceptibility to lead exposure.

192 However, identifying genes that give rise to individual variation in susceptibility to lead toxicity

193 Our results may also help to explain individual variation in susceptibility to opioid medicat

194 preclinical approach for studying sources of individual variation in susceptibility to relapse due to

195 Genetic epidemiological studies suggest that individual variation in susceptibility to schizophrenia

196 was predicted to be most sensitive to inter-individual variation in the activity of enzymes which, e

197 ating telomere dynamics may help us quantify individual variation in the costs experienced from socia

198 of multiple neuropsychiatric disorders, and individual variation in the degree of inherent impulsivi

199 rain dynamics offer a neural explanation for individual variation in the error dynamics of human beha

200 There is considerable individual variation in the extent to which reward cues

201 ve splicing is a mechanism that accounts for individual variation in the human population.

202 Individual variation in the Ig germline gene repertoire

203 study designs are starting to explain inter-individual variation in the immune response.

204 There was a wide range of individual variation in the level of compliance among in

205 reveals for the first time substantial inter-individual variation in the NCO:CO ratio.

206 me Humain Utah pedigrees, we found extensive individual variation in the number of female and male re

207 G6PD heterozygous females, because of individual variation in the pattern of X-chromosome inac

208 Individual variation in the presence of pain, rather tha

209 There is, however, considerable individual variation in the propensity to attribute ince

210 conflict-based relapse model to ask whether individual variation in the propensity to attribute ince

211 uld be chosen conservatively or adjusted for individual variation in the rate at which washout occurs

212 polymorphisms that are responsible for inter-individual variation in the response to drug therapy.

213 relative contribution of genetic factors to individual variation in the shape of seven bilateral sub

214 Despite individual variation in the shape of V1, the relationshi

215 to retinotopy generally, is the substantial individual variation in the size, volumetric position, a

216 Individual variation in the strength of this functional

217 Given individual variation in the susceptibility to NODAT, we

218 Children aged 5-12 y show individual variation in their responsiveness to energy d

219 emphasize the need for incorporating between-individual variation in theoretical and empirical studie

220 However, even in adolescence considerable individual variation in these behaviors exists, which ma

221 Individual variation in these mechanisms may stem from v

222 However, the inter-individual variation in this risk is poorly understood.

223 l magnetic resonance imaging, we report that individual variation in trait reward sensitivity (as mea

224 and unique environmental factors to between-individual variation in traits.

225 patterns of clinical manifestation and inter-individual variation in viral load dynamics.

226 Gastric bypass was associated with less individual variation in weight loss than gastric band.

227 Finally, we asked whether individual variation in wheel use within a group of mice

228 Individual variation in WM has been associated with mult

229 Individual variations in aversive pruning levels related

230 tions in these connections may be related to individual variations in behaviour and cognition.

231 the GT6 family generate species-specific and individual variations in carbohydrate structures, includ

232 approximately 2% Gly(241) alleles) points to individual variations in complex formation.

233 techniques to investigate the main source of individual variations in contrast sensitivity.

234 tioned reinforcement from positive cues, and individual variations in decision strategy and the cogni

235 classification and greater understanding of individual variations in disease pathology could drive t

236 e robust to both noise in light and to inter-individual variations in endogenous circadian period tha

237 Overall, this suggests that inter-individual variations in fear generalization and anxiety

238 Previous studies have revealed large inter-individual variations in fear responding with clinically

239 and has quantitative implications for inter-individual variations in glucose/insulin homeostasis.

240 iations (p<0.05) between gene SNPs and inter-individual variations in IFN-alpha, IL-12p40, IL-1beta,

241 ar viral replication and cancer development, individual variations in mRNA editing and the genetic tr

242 Individual variations in NAC response to reward expectat

243 e nucleotide polymorphism (SNP) rs563649 and individual variations in pain perception.

244 ed the degree of CHT mobilization as well as individual variations in performance on the sustained at

245 sychological states and contexts, as well as individual variations in physiological arousal, may help

246 proaches may be adversely affected by common individual variations in skull anatomy.

247 I hypothesize that individual variations in society result in higher energe

248 Individual variations in structure and morphology of amy

249 otransmission was positively associated with individual variations in subjective ratings of sensory a

250 We found that, regardless of individual variations in TCR-Vbeta repertoires, the pres

251 task-evoked activity, it is unclear whether individual variations in the connectivity pattern of a b

252 There are remarkable population and individual variations in the formation of TMSe, which co

253 It concludes by outlining how individual variations in the inflammatory response could

254 Individual variations in the innate immune response to r

255 responses to pain and that it contributes to individual variations in the pain experience at the leve

256 ility in trait anxiety is causally linked to individual variations in the physiological constitution

257 nnections (correlations in time series), and individual variations in these connections may be relate

258 Inter-individual variations in these factors probably explain

259 malism-hypergraph cardinality-we investigate individual variations in two separate, complementary dat

260 nd empirical investigations of the bases for individual-variation in political ideology.

261 rsal in that they occur worldwide, with some individual variation, in completely unrelated languages.

262 he bacterial surface and the actin tail, and individual variation is determined by long-lived intrins

263 l direct contacts, such as SARS or smallpox, individual variation is difficult to measure empirically

264 onal point between a microscopic scale where individual variation is prominent and the macroscopic le

265 Compelling intuitive arguments suggest that individual variation may provide a previously unrecognis

266 y of the visual system [4,7,8] suggests that individual variations may be found in even more basic vi

267 are a major contributing factor to the inter-individual variation observed in response to human immun

268 te obesity genes may account for some of the individual variation observed in short-term energy compe

269 However, most individual variation occurs outside of genes and, indeed

270 less than 20% inhibition of BChE) because of individual variation of BChE values but also avoids the

271 ,700 lipids) accounted for >60% of the inter-individual variation of BMI, WC, and leptin in our popul

272 Little is known about the inter-individual variation of cytokine responses to different

273 ion, focusing on transcripts for which inter-individual variation of expression in brain correlates w

274 disease ecology is to understand the role of individual variation of infection load on disease transm

275 We have characterized inter- and intra-individual variation of microbial communities of 107 ind

276 ve parameters (fixed effect) and the between-individual variation of these parameters (random effect)

277 Accordingly, we explored inter-individual variations of functional connectivity dynamic

278 strates of individuality, reflected in inter-individual variations of large-scale functional connecti

279 ants into mice can further define effects of individual variation on normative development, how they

280 ch to understanding the impact of pre-morbid individual variation on post-lesion outcomes that could

281 Here, we test the effect of individual variation on the long-term trajectories of bi

282 9 and miR-146 and has implications for inter-individual variations on cardiometabolic traits.

283 cated CpG sites accounted for up to 6% inter-individual variation (R2) of age-adjusted and sex-adjust

284 ailed annotation provides interpretation for individual variation responsible for normal and disease

285 Plots of individual variation (SD) against mean error allowed the

286 the same time higher and subject to a larger individual variation than previously assumed.

287 memories than others, given the substantial individual variation that exists in retrieval ability an

288 y of oral disease in these animals, suggests individual variation that is reflected in the characteri

289 use appropriate procedures remain subject to individual variation that statistical methods cannot cor

290 contributions of developmental programs and individual variation to behavior by monitoring single Ca

291 ce understanding of adolescent potential and individual variation to further generate developmentally

292 hese results emphasize the need to integrate individual variation to generate new insights when model

293 a h 2 (rho(s) = 0.60, P < 0.0001), but large individual variation was found.

294 hin any one tissue, we found that some inter-individual variation was reflected across brain and bloo

295 mained very low compared to documented inter-individual variation, we suggest that male koalas would

296 To shed light on the origin of these inter-individual variations, we subjected rats to a differenti

297 ding drives genomic evolution and eliminates individual variation, while fixing certain sets of allel

298 Here, we tested the importance of inter-individual variation with respect to the physiology of c

299 sents an opportunity to address the basis of individual variation within a rare and complex disorder.

300 Although this can vary widely between individuals, variation within an individual and the asso