ライフサイエンスコーパス: individualization

1 movement was used to follow the progress of individualization.

2 lk cytoplasm in a process known as spermatid individualization.

3 nd SWNTs and impart effective dispersion and individualization.

4 nt of the IC whose function is essential for individualization.

5 interconnected by cytoplasmic bridges until individualization.

6 terility as a result of defects in spermatid individualization.

7 rticipates in membrane reorganization during individualization.

8 ls, a process sometimes referred to as sperm individualization.

9 cones that mediate D. melanogaster spermatid individualization.

10 d in Drosophila male fertility and spermatid individualization.

11 s in MTHFR may offer potential for treatment individualization.

12 dinated migration of investment cones during individualization.

13 sterile due to specific defects in spermatid individualization.

14 called actin cones, which mediate spermatid individualization.

15 r cytokinesis and those that failed in sperm individualization.

16 te-stage spermatid differentiation following individualization.

17 nfusion was modified to 4 hours, with dosage individualization.

18 Dose individualization according to TMTV0 should be evaluated

19 Individualization also fails in a number of mutants with

20 amined the timing and dynamics of phenotypic individualization among sister cells by scrutinizing and

21 fficient use of donated organs and allow the individualization and better evaluation of adjuvant chem

22 in a helical pattern that imparts efficient individualization and chirality selection.

23 Even if topoisomerase II is required for individualization and condensation of meiotic chromosome

24 in spindle assembly, which delay chromosome individualization and congression, putting the oocyte at

25 at an early time point, permitting treatment individualization and consideration of alternative strat

26 r that the intervention needs to incorporate individualization and long-term interaction with trained

27 rile and show spermatogenic defects in sperm individualization and nuclear maturation, consistent wit

28 cteristics offer opportunities for treatment individualization and optimal patient selection for anti

29 Use of this tool may allow the individualization and optimization of therapeutic strate

30 Each trial incorporated individualization and repeated long-term contacts with f

31 arable functions: one required for spermatid individualization and the other essential for assembling

32 he final stage of spermatogenesis, spermatid individualization, and causes male sterility.

33 visions to later stages of sperm maturation, individualization, and motility.

34 c activities of condensin (axial compaction, individualization, and resolution of recombination-depen

35 or ECT and 26% for MST, supporting amplitude individualization as a means of dosing especially for EC

36 g forces and is directly analogous to sister individualization at the prophase to prometaphase transi

37 epsis, interventional therapies will require individualization based on the age of the population.

38 x of cytoskeletal proteins and membrane, the individualization complex (IC), around the spermatid nuc

39 M1L males is caused by the disruption of the individualization complex and a progressive loss of germ

40 antly retard the assembly of the actin-based individualization complex around the nuclear bundle, (2)

41 low the assembly of a morphologically normal individualization complex around the nuclear bundle, but

42 ion of a major cytoskeletal component of the individualization complex as actin is confirmed with a s

43 ndle, (2) mutations (dud class) in which the individualization complex assembles in/around the nuclea

44 The structure of the individualization complex in a male-sterile clathrin hea

45 Using rhodamine-phalloidin as a probe, the individualization complex is readily visualized forming

46 ver leads to defects in the formation of the individualization complex that is required for spermatid

47 otile but morphologically altered or reduced individualization complex.

48 physical scaffolding for the assembly of the individualization complex.

49 sruption of the actin cones of the spermatid individualization complex.

50 these structures and other components of the individualization complex.

51 isplayed a postmeiotic lesion with disrupted individualization complexes scattered along the spermati

52 bunits are found in numerous ;speckles' near individualization complexes, similar to the previously d

53 Individualization complexes, which consist of 64 cones o

54 e sterile phenotype derives from a spermatid individualization defect at a late stage of spermatogene

55 d relative to wild-type, consistent with the individualization-deficient phenotype of this mutant.

56 nd kl-5 mutations had no effect on spermatid individualization despite the defect in the axonemes.

57 s and recapitulate chromosome compaction and individualization during mitotic condensation.

58 to better understand the mechanism of sperm individualization during spermatogenesis in Drosophila m

59 The whole process of individualization, during which a bundle of 64 syncytial

60 on condensation of chromatin and chromosome individualization from prophase to metaphase transition.

61 Computerized dose individualization improves target concentration achievem

62 eins play an essential role during spermatid individualization in Drosophila melanogaster.

63 ganization also become apparent during sperm individualization in dVps28 mutant testis.

64 in which we can perform live observation of individualization in isolated cysts.

65 L, which may have implications for treatment individualization in this disease.

66 rapeutic opportunities for further treatment individualization in this genetically defined subset of

67 I using observations of Drosophila spermatid individualization in vivo.

68 rticular repeated element and its subsequent individualization into a fully functional character.

69 The process of individualization involves the formation of a complex of

70 Furthermore, we find that this individualization is an active process that requires a l

71 ed forces deep into the tissue and that cell individualization is dispensable.

72 reorganization of cyst cytoplasm required at individualization is expected to be a correspondingly co

73 The associated process, termed spermatid individualization, is facilitated by the apoptotic machi

74 fy the variables most relevant to subsequent individualization of a cancer therapy.

75 Drug monitoring allows individualization of a patient's immunosuppressive thera

76 Purported benefits are individualization of adjuvant therapy based on extent of

77 Individualization of antiangiogenic treatment using data

78 ous tumors and to improve the monitoring and individualization of antiangiogenic treatments.

79 baseline platelet hyperreactivity; 2) allow individualization of antiplatelet medication; 3) predict

80 If so, the individualization of antiplatelet therapy, including clo

81 more, quantitative molecular tests allow the individualization of antiviral therapies for prevention

82 tion may have important implications for the individualization of cancer chemotherapy.

83 or the identity of genes that may enable the individualization of cancer chemotherapy.

84 Individualization of cancer management requires prognost

85 lial, and inflammatory cell interactions and individualization of care will result in the eventual de

86 ithin each lineage, then further modified by individualization of cells as they acquire unique morpho

87 om a mere detection method to application in individualization of chemoradiotherapy.

88 In this post-genomic era, the individualization of chemotherapy through the study of p

89 optimization of new drug development and the individualization of clinical therapeutics in the 21st c

90 s has offered compelling evidence toward the individualization of clopidogrel and warfarin therapies.

91 ation for the Study of Diabetes, emphasizing individualization of DM medication therapy and treatment

92 of convenience, cost, and safety, but limit individualization of dosing.

93 ion of specialized machinery involved in the individualization of Drosophila spermatids, and of many

94 ggest these reactions may be avoided through individualization of drug therapies based on genetic inf

95 The individualization of HbA(1c) targets has gained more tra

96 This, in turn, may serve as a tool for individualization of immunosuppression protocols in hear

97 mmatory status may be helpful in prospective individualization of immunosuppression therapy after ren

98 Individualization of management and adequate supportive

99 e of clinical nuclear medicine as a tool for individualization of patient care and for improvement of

100 -sensitive reperfusion strategies, allow for individualization of patient care by predicting relative

101 thyroid cancer are expected to allow greater individualization of patient care.

102 logy and user interfaces will permit greater individualization of prevention and treatment strategies

103 oxifene in endometrial cancer prevention and individualization of SERM therapy.

104 excessive standardization and a decrease in individualization of services.

105 nd supportive of our previous proposals that individualization of sisters in E. coli is driven primar

106 CDH2, allowing for segmental de-adhesion and individualization of somites.

107 e prole disrupt spermatogenesis at or before individualization of spermatozoa and cause multiple defe

108 col biopsies provide information that allows individualization of tacrolimus rejection therapy, 2) hi

109 tides was found, suggesting a high degree of individualization of the HLA peptidomes.

110 h-risk subjects could contribute to a better individualization of the pharmacological treatment in ps

111 monitoring techniques emphasize the need for individualization of therapeutic interventions.

112 Individualization of therapy based on genetic and enviro

113 use of available resources is expected from individualization of therapy regimens, which comprises t

114 ter identification of endotypes might permit individualization of therapy that can be targeted agains

115 tment education of anticipated side-effects, individualization of therapy, and review of strategies f

116 oaches and provide opportunities for greater individualization of therapy, confirmation of the geneti

117 ircumstances, might have clinical utility in individualization of therapy, early diagnosis and the ri

118 Individualization of therapy, which tailors a therapeuti

119 The hallmark of pain management is individualization of therapy.

120 is highly test specific, and does not allow individualization of therapy.

121 d preclinical diagnosis, prognostication and individualization of therapy.

122 d preclinical diagnosis, prognostication and individualization of therapy.

123 ding of arterial afterload may enable better individualization of therapy.

124 function of allograft recipients for better individualization of therapy.

125 in A(1c) (HbA(1c)) targets for patients, and individualization of these goals has more recently been

126 because of its importance clinically for the individualization of thiopurine drug therapy and also be

127 uggest strategies for moving biomarker-based individualization of transplant care from a research hyp

128 he underlying pathophysiology and subsequent individualization of treatment goals are important for i

129 to determine whether it may be useful in the individualization of treatment or evaluation of the resp

130 of breast cancer, which in turn aids in the individualization of treatment.

131 tment, and could allow dose optimization and individualization of treatment.

132 tibility to ara-C cytotoxicity may allow for individualization of treatment.

133 le prevention of VTE recurrence with minimal individualization of treatment.

134 l aortic waveform analysis may enable better individualization of vasoactive therapies in chronic HF

135 -apoptotic role for these factors during the individualization process of maturing spermatids.

136 nstrated that long-range control of follicle individualization requires stall gene function in cells

137 h within and outside the ovary, for follicle individualization, stalk cell intercalation, and oocyte

138 expression is necessary for proper spermatid individualization, the terminal step necessary for produ

139 Computerized dose individualization using population pharmacokinetic model

140 ly, emerging trends such as connectivity and individualization will also drive new technology, and th

141 A second activity promotes chromosome individualization with the help of Red1 and Hop1, two me