ライフサイエンスコーパス: inducibility

1 l ion channel gene expression and arrhythmia inducibility.

2 conduction velocity, and atrial fibrillation inducibility.

3 -entrant duration while minimally increasing inducibility.

4 ffect of different induction protocols on AF inducibility.

5 ndicating among-habitat variation in defence inducibility.

6 eat lengths linked to decreased activity and inducibility.

7 n, followed by weekly testing for arrhythmia inducibility.

8 n of the IL17A promoter indeed abrogates its inducibility.

9 that depend on MybE and DimB for their DIF-1 inducibility.

10 DimB and MybE transcription factors for full inducibility.

11 , restored polII and TBP binding, and CYP1B1 inducibility.

12 tron structure, basal expression, and stress inducibility.

13 s for growth-phase regulation and DNA damage inducibility.

14 ulted in a significant loss of ITGB1 hypoxia-inducibility.

15 ter identified a region important in hypoxia inducibility.

16 t 3' HRE contributes the most toward hypoxia inducibility.

17 the CCL2 promoter is required for hypertonic inducibility.

18 cible patients) were considered positive for inducibility.

19 hich make a major contribution toward dioxin inducibility.

20 lionated plexi abolished atrial fibrillation inducibility.

21 ereas atropine abolished atrial fibrillation inducibility.

22 atrial fibrosis is sufficient to increase AF inducibility.

23 CD18 promoter resulted in a loss of hypoxia inducibility.

24 nd 7900 appears to act as a repressor of dex inducibility.

25 play roles as independent repressors of this inducibility.

26 7%) cytochalasin D and significantly reduced inducibility.

27 esulted in a nearly complete loss of hypoxia-inducibility.

28 ricular tachycardia/ventricular fibrillation inducibility.

29 nsfected into rat hepatocytes and tested for inducibility.

30 by a unique polylinker, had no effect on dex inducibility.

31 ly useful due to its high catalytic rate and inducibility.

32 s is also associated with CK variability and inducibility.

33 lectrical properties and atrial fibrillation inducibility.

34 ricular tachycardia/ventricular fibrillation inducibility.

35 phosphokinase (CK) levels, CK variation, and inducibility.

36 al fat pads can suppress atrial fibrillation inducibility.

37 physiological study was performed to test VA inducibility.

38 tervals [0.57-0.96]) were associated with VA inducibility.

39 e switch also substantially improved ethanol inducibility.

40 of the underlying substrate differs with VT inducibility.

41 ctionated signals increased with time and VT inducibility.

42 ase-reporter muscle cells revealed NF-kappaB inducibility.

43 ximal promoter are essential for optimal LPS-inducibility.

44 further reductions in duration and increased inducibility.

45 n voltage or velocity substrate with time or inducibility.

46 my model to allow for spatial variability in inducibility.

47 city, conduction heterogeneity index, and AF inducibility.

48 d conduction locally, and increased re-entry inducibility (23%), without increasing triggered activit

49 as performed when recurrent VT or persistent inducibility after ENDO-only ablation.

50 was performed for recurrent VT or persistent inducibility after endocardial-only ablation.

51 (e.g., >50% reduction in atrial fibrillation inducibility after I(K,ACh-c) blockade).

52 d conduction velocity and lowered arrhythmia inducibility after MI, suggesting a new approach for arr

53 plasticity of striatal immediate early gene inducibility after repeated AMPH administration.

54 In line with its auxin inducibility and binding to auxin response elements of r

55 red mouse strains reflect variations in CYP1 inducibility and clearly have been shown to be associate

56 ffect of various ablation lesion sets on the inducibility and duration of MWR as a function of ablati

57 The inducibility and earliest presystolic endocardial activa

58 The inducibility and effects of DBI-TSPO signaling in the re

59 nt show strong relationships between network inducibility and fitness.

60 af specificity, mesophyll specificity, light inducibility and high activity, that distinguish the uni

61 ve pathogens operates in 'real time' showing inducibility and increases in affinity.

62 Because the absolute level of estradiol inducibility and inhibition by TCDD was similar in eithe

63 We thus tested the inducibility and longevity of HC-Ad-mediated transgene e

64 d from a range of chromosomal loci with high inducibility and low background generating insertions th

65 ion of the transgene, often cause suboptimal inducibility and make the isolation of tightly regulated

66 basis for the epigenetic control of [PSI(+)] inducibility and may reveal a broader role for this phen

67 Based on hchA heat-inducibility and membership in the sigmaS general stress

68 pective analysis, we compared the rate of VT inducibility and outcome of MUSTT-enrolled patients with

69 cause of its ubiquitous distribution, stress inducibility and participation in tolerogenic processes.

70 CV that dramatically reduces both arrhythmia inducibility and resulting complexity by increasing wave

71 spread), and reduced ventricular tachycardia inducibility and sudden cardiac death.

72 achycardia/ventricular fibrillation (VTs/VF) inducibility and to identify additional predictors of ar

73 Atrial effective refractory period, AF inducibility, and duration of individual episodes of AF

74 These differences in inducibility are not associated with detectable variatio

75 response element (ISRE) responsible for IFN-inducibility, as well as an adjacent upstream sequence,

76 Inducibility at electrophysiologic study (hazard ratio:

77 Proband status (p < 0.001), inducibility at electrophysiologic study (p = 0.005), pr

78 Inducibility at electrophysiologic study and nonsustaine

79 isolate mutant promoters that retained high inducibility but exhibited reduced basal level expressio

80 moter reporter gene constructs abrogated the inducibility by cAMP.

81 at determine cell specificity also determine inducibility by ethylene, auxin, and root separation.

82 LURP1 shows the most extreme transcriptional inducibility by H. parasitica of all LURP and PR1 regulo

83 cts, a minimal cis-acting element conferring inducibility by hypoxia and deferoxamine was localized t

84 e Egr-1 binding site, which reduced promoter inducibility by hypoxia and deferoxamine.

85 e divided into two groups according to their inducibility by IFN and virus infection: one induced onl

86 reduction in Ang-1 transactivation by ESE-1, inducibility by inflammatory cytokines, and DNA binding

87 d between basal transcriptional activity and inducibility by Tat.

88 whose discovery was based on its pronounced inducibility by the glucocorticoid dexamethasone.

89 Selective suppression of TdP inducibility by W-7, without shortening the duration of

90 g mutagenesis, we have demonstrated that the inducibility can be attributed to the imperfect substrat

91 Our study shows that dexamethasone inducibility can be useful to silence vital genes in tra

92 ducible E-selectin and VCAM-1 whereas ICAM-1 inducibility decreased.

93 We compared a narrow inducibility definition (only monomorphic VT) and a broa

94 A "standard" inducibility definition included sustained monomorphic o

95 The narrow inducibility definition outperformed the standard defini

96 Standard inducibility did not predict the combined end point of V

97 Inducibility during programmed electrical stimulation wa

98 ct on cell growth, plasmid stability or DNAi inducibility even after passaging for >2 months.

99 d by the presence of a transplanted [PSI(+)] inducibility factor, a distinct prion that is required f

100 TB with intact membranes (<34 weeks) and the inducibility fetal membrane senescence phenotype by oxid

101 bp region of the CD55 gene conferred hypoxia inducibility for CD55.

102 farct periphery was strongly associated with inducibility for monomorphic ventricular tachycardia (no

103 ure beats, decreased ventricular tachycardia inducibility (from 90% to 17%; P<0.05), diminished eleva

104 development; if a candidate drug shows CYP1 inducibility, further testing is generally discontinued

105 nts undergoing programmed stimulation for VT inducibility had monophasic action potential recording/p

106 nificance of these binding sites in caffeine-inducibility has been discussed.

107 n linked to individual variation in cytokine inducibility has been strongly implicated in several pat

108 istance genes, the molecular basis for their inducibility has remained unknown.

109 as risk factors: electrophysiological study inducibility (hazard ratio, 11.4; P<0.01), spontaneous t

110 ncluding polymorphic VT in the definition of inducibility improved sensitivity (66.1+/-6.0% versus 77

111 T-1 and CAAT motifs are able to confer BRCA1 inducibility in a non-related minimal promoter.

112 f RyR2 in Ryr2S2814A knockin mice reduced AF inducibility in a vagotonic AF model.

113 Aor yielding dihydro-15d-PGJ2 abolishes the inducibility in an antioxidant response element-driven l

114 egulation, slowed conduction, and arrhythmia inducibility in Cav1(-/-) animals.

115 factor Su(H) is bound by Su(H) and confers N-inducibility in cultured cells.

116 synthase genes that exhibited impaired auxin inducibility in dgt hypocotyls.

117 phric mesenchyme does not display defects in inducibility in LiCl or spinal cord induction assays.

118 ified transactivator to maintain homogeneous inducibility in long-term culture has not been examined.

119 in (GFP) reporter also exhibited homogeneous inducibility in long-term culture.

120 attracted considerable interest based on its inducibility in multiple injury processes and accumulati

121 eremic MBF impairment may be related with VA inducibility in patients with ischemic cardiomyopathy.

122 oronary flow reserve were associated with VA inducibility in patients with ischemic cardiomyopathy.

123 o peak Ecc showed positive correlation to VT inducibility in patients with prior MI and left ventricu

124 ory periods and supraventricular tachycardia inducibility in recent invasive electrophysiologic studi

125 T7 promoter-GUS transgenic plants show rapid inducibility in response to ozone and pathogens.

126 t the obtained reporter system i) has a high inducibility in response to treatments leading to HIF-1a

127 nd genetic inhibition of CaMKII prevented AF inducibility in Ryr2R176Q/+ mice.

128 nto the fat pad, resulting in the loss of AF inducibility in six of seven dogs at the same AG stimula

129 6a8 genes respectively did not show caffeine-inducibility in SL-2 cells, the longest upstream DNA of

130 te (the absence of tetracycline) and greater inducibility in the on state (the presence of tetracycli

131 from hypothyroidism to hyperthyroidism on AF inducibility in thyroidectomized rats.

132 hypertrophic cardiomyopathy, and arrhythmia inducibility in transgenic animals, which correlated wit

133 atrial APD and increased atrial fibrillation inducibility in vivo.

134 AF inducibility increased after 16 weeks of training (e.g.,

135 of the HPV31 GREs in HPV18 only showed weak inducibility, indicating that the three GREs of HPV31 ar

136 ariation in constitutive gene expression and inducibility, indicating that these genes may be associa

137 AhR expression constructs confirm that TCDD-inducibility is AhR-dependent and requires direct AhR-DN

138 This reduced inducibility is associated with an altered stability of

139 revious work has indicated that this loss of inducibility is attributable to Oct-1 binding to the HLA

140 These data suggest that the lack of dex inducibility is due to the overall context of the HPV31

141 distinct contrast, we show here that CYP1A1 inducibility is essential in the detoxication of oral Ba

142 IAA inducibility is gene-specific and cell type-dependent ac

143 These data suggest that ISG inducibility is important for the treatment response and

144 s of the PpLEA-1 promoter indicates that ABA-inducibility is mediated via an ACGT-core motif similar

145 l promoter and the region governing the heat inducibility is possibly shared between the two genes.

146 Previous studies show that MCP-1 inducibility is regulated by an AP-1 complex composed of

147 Remarkably, the inducibility is reversible after withdrawal of the induc

148 Our data show that VT/VF inducibility is unable to identify high-risk patients, w

149 bers of the Sp/KLF family due to its TGFbeta inducibility, its ability to regulate the TGFbetaRII pro

150 ecessary and sufficient to have high network inducibility levels as in S. paradoxus.

151 DNA damage inducibility occurred in strains unable to synthesize (p

152 Partial success (inducibility of a nonclinical VT only: 50%) and failure

153 lso leads to nuclear damage, as evidenced by inducibility of a nuclear DNA damage reporter, increased

154 Second, E75A can potentiate the JH inducibility of a secondary response gene, JhI-21.

155 patterns, effective refractory periods, and inducibility of AF.

156 ormal sinus rhythm at admission for EAM, and inducibility of any sustained tachyarrhythmia at the end

157 The inducibility of arachidonic acid and the cyclooxygenase

158 with arrhythmogenesis, as well as increasing inducibility of arrhythmia.

159 d cortical excitability along with decreased inducibility of associative synaptic long-term potentiat

160 e studied cardiac electrophysiology (EP) and inducibility of atrial arrhythmias in MHC-TGFcys33ser tr

161 Inducibility of atrial fibrillation (AF) after pulmonary

162 isolates are susceptible to fluconazole, the inducibility of azole resistance in vitro has been repor

163 The inducibility of CD8+CCR7+ Tregs is correlated with the a

164 ased K5; these changes were accompanied with inducibility of cell-cell adhesion by nocodazole.

165 to suggest that the variant has an impact on inducibility of CK by trauma through a previously report

166 n 17 patients (38%), and failure (persistent inducibility of clinical VT) in 11 patients (24%).

167 inical VT only: 50%) and failure (persistent inducibility of clinical VT: 12.5%) was attributed to in

168 The inducibility of CM gradually increases with age in assoc

169 A reduced inducibility of COX-2 but preserved inducibility of mPGE

170 The inducibility of CX3CR1 expression was not solely depende

171 d-type STAT3 in DRST3 cells restored the IFN inducibility of CXCL11.

172 The dioxin-inducibility of CY2S1 is exceptional, because all previo

173 We have also found that the inducibility of CYP1A1 and CYP1B1 transcripts following

174 ated nuclear translocation of CAR as well as inducibility of CYP1A2, CYP2B10, CYP3A11, and CYP7A1 exp

175 of multiple RAREs may account for the strong inducibility of CYP26A1 in liver, which, in turn, may be

176 ibute to the large individual variations and inducibility of CYP2B6 in humans.

177 ing site in the CYP2C8 promoter that confers inducibility of CYP2C8 via the PXR agonist/ligand rifamp

178 The inducibility of different isoflavonoid subclasses in see

179 The inducibility of DNA adducts following in vitro treatment

180 , followed by extended withdrawal, increases inducibility of Fosb in NAc, as evidenced by greater acu

181 nducible temperature, and thus likely confer inducibility of gene expression and higher responsive dy

182 t, we performed experiments to test the heat inducibility of heat shock protein (hsp) 70 promoter and

183 sis of multivariate analysis, postprocedural inducibility of index VT was independently associated bo

184 of nondocumented VT) in 12.4%, and class C (inducibility of index VT) in 10.6%.

185 zipper domains to confer lipopolysaccharide inducibility of interleukin-6, suggest that the C/EBP le

186 There are no studies of the frequency of inducibility of IP during PCI, nor are there longer-term

187 M kinase in AT cells restored the DNA damage inducibility of IRF-1, whilst the PI-3 kinase inhibitor

188 blab and Psophocarpus, were investigated for inducibility of isoflavonoids by germination with or wit

189 The acid inducibility of lipF and Rv0834c was independent of the

190 y NLRX1 seemed to correlate with the dynamic inducibility of luciferase reporter constructs.

191 T/beta-catenin pathway on the regulation and inducibility of major human P450 enzymes, HepaRG cells w

192 king reduced Cx43 abundance in the heart and inducibility of malignant ventricular arrhythmias have y

193 n several cell types was correlated with the inducibility of MKP-1 by t-RA.

194 infarcted myocardial tissue can help predict inducibility of monomorphic ventricular tachycardia (VT)

195 Relationships between inducibility of monomorphic VT, peak Ecc, and time to pe

196 reduced inducibility of COX-2 but preserved inducibility of mPGES-1 on gene expression level were co

197 Importantly, the inducibility of mprF and dlt transcription via the graRS

198 ts in reduced neovascularization and blunted inducibility of multiple proangiogenic factors in the re

199 s and surface area were better predictors of inducibility of MVT than LVEF.

200 n the probability of MWR termination and the inducibility of MWR, as a function of lesion length and

201 y minimally decreased duration yet increased inducibility of MWR.

202 In addition, eCBs can modify the inducibility of non-eCB-mediated forms of plasticity.

203 cess (elimination of clinical VT, persistent inducibility of nonclinical VT) in 17 patients (38%), an

204 was obtained in 371 patients (77%), class B (inducibility of nondocumented VT) in 12.4%, and class C

205 Importantly, the DNA modification state and inducibility of odorant-activated genes are markedly imp

206 nslational termination, nitrogen regulation, inducibility of other prions, and heterokaryon incompati

207 whereas endotoxin tolerization abrogated LPS inducibility of Pellino-1.

208 ty (14% versus 0% in controls) and increased inducibility of re-entry (53% versus 6% in controls) wer

209 dependently increased APD90, APD dispersion, inducibility of re-entry and affected specific ion chann

210 Inducibility of refibrillation was assessed after initia

211 The ABA inducibility of some of the rice genes identified was va

212 MRI indices were related to inducibility of sustained monomorphic ventricular tachyc

213 on of multiple enhancers underlies the broad inducibility of the c-fos gene.

214 The hypoxia inducibility of the C-P4H isoenzymes is thus likely to e

215 erization site at Y705 mutated, restored IFN inducibility of the CXCL11 gene.

216 Here we report the JH inducibility of the E75A nuclear receptor encoded by the

217 tory of cocaine exposure in rats might alter inducibility of the Fosb gene elicited by subsequent dru

218 ver, it could not be shown to account for PB inducibility of the gene.

219 ted mutagenesis of three novel PPREs reduced inducibility of the MDR3 promoter by fenofibrate.

220 eas mutation of the Ets sites abolished, the inducibility of the promoter construct.

221 osphorylation site eliminates the DNA damage inducibility of the protein.

222 ding protein (CREB) completely abolished the inducibility of the reporter gene activity by forskolin.

223 dancy among the four ubiquitin genes, stress inducibility of the two polyubiquitin genes, and ubiquit

224 We attempt to show here inducibility of the URR of HPV31 by the synthetic glucoc

225 ported to be important for the serum and TPA inducibility of the vimentin gene.

226 ion of zCAT function enhances light-mediated inducibility of these clock genes.

227 ted) showed higher baseline levels and lower inducibility of these genes in response to in vitro inte

228 rbicide safeners, demonstrating the chemical inducibility of this detoxification system in Arabidopsi

229 In support of this hypothesis, we find 1) inducibility of tobacco RSH gene expression following tr

230 Here, we exploit this inducibility of VEGFR3 to engineer mouse melanoma models

231 Inducibility of ventricular arrhythmias on an electrophy

232 al Cav1, which is accompanied with increased inducibility of ventricular arrhythmias.

233 Inducibility of ventricular tachycardia (VT) has limited

234 TWA has been shown to predict inducibility of ventricular tachycardia with programmed

235 TWA has been shown to predict inducibility of ventricular tachycardia with programmed

236 Inducibility of ventricular tachycardia/ventricular fibr

237 The inducibility of VF after dantrolene administration was d

238 n, effects that were associated with reduced inducibility of VF with CL(VF).

239 Inducibility of VT at electrophysiologic study (EPS) and

240 on the eighth day after infarction abolished inducibility of VT at late induction studies </=200 days

241 Even though its value has been questioned, inducibility of VTs/VF is widely used to select candidat

242 Further, the inducibility of ZIP4 and ZIP12 in response to cadmium (c

243 nalysis, aborted sudden cardiac death and VA inducibility on electrophysiologic studies were independ

244 eplace this domain and confer p21(waf1/cip1) inducibility on p300.

245 Three of seven dogs showed AF inducibility only with AG stimulation >/=9.3 V.

246 ss, restriction to proliferating cells, slow inducibility or complex genetics.

247 otassium channel block has no effect on PVEM inducibility per se, but shifts it to later time points

248 PP1: 41 cm/s, p < 0.05) and lower arrhythmic inducibility (PP3: 71%, PP1: 35%, p < 0.05) than PP3 mic

249 In the MADIT II study, inducibility predicted an increased likelihood of VT but

250 ably triggers PVEM at the contact site, with inducibility predicted by local tissue indentation.

251 Ventricular arrhythmias inducibility presented a hazard ratio for events of 8.3

252 ces paradoxus, measure the resulting network inducibility profiles, and model the results.

253 At the multivariate analysis, only inducibility remained significant (hazard ratio, 9.1; P<

254 RSF to ERSE and maximal ERSE-mediated stress inducibility require the conserved GGC motif within the

255 understanding molecular pathways of hypoxia inducibility revealed that a approximately 200 bp region

256 Ventricular arrhythmia inducibility, spontaneous type I ECG, and presence of si

257 lemetry electrocardiographic monitoring, and inducibility studies.

258 no effect on repression but produced loss of inducibility, suggesting that both Cys-12-Cys-13 and Cys

259 tain cell-type-specific programming for IL-2 inducibility through many rounds of division without bei

260 reverse-transcriptase PCR revealed nematode inducibility throughout the duration of nematode infesta

261 tain sequences sufficient to confer ecdysone inducibility to a reporter gene.

262 In this setting, the value of inducibility to stratify individuals with BrS has change

263 This DNA enhancer also confers cytokine inducibility to the heterologous thymidine kinase (TK) p

264 tial tumor necrosis factor-alpha (TNF-alpha) inducibility to the IFNG promoter.

265 on of this AP-1/Smad box conferred TGF-beta1 inducibility to the non-responsive -3.97kb NOX4 promoter

266 mCAR but not hCAR conferred drug inducibility to the proximal -2145 bp of the CYP2C9 prom

267 the SRE and ATF sites imparted a strong TPA-inducibility to the reporter.

268 discrete and measurable end point beyond VT inducibility to treat patients with multiple or unmappab

269 d species, with high selectivity indexes and inducibility under hypoxia-mimetic conditions.

270 CYP1A1*2B (Val) high-inducibility variant allele was overrepresented in patie

271 on mixed carbon sources, but their degree of inducibility varied when the substrate was either cellul

272 VT inducibility was also assessed.

273 VT inducibility was associated with all-cause mortality (ad

274 In the MADIT II study patients, inducibility was associated with an increased likelihood

275 VT inducibility was associated with higher VT recurrence (a

276 The degree of the inducibility was associated with severity of sepsis and

277 cible Nfatc1 promoter activity, whereas this inducibility was attenuated in NFATc2(-/-) splenocytes.

278 cell patch-clamping, and atrial fibrillation inducibility was evaluated by transoesophageal atrial bu

279 VT inducibility was influenced by the distribution of condu

280 ricular tachycardia/ventricular fibrillation inducibility was larger in WT than in LDLr(-/-) and ApoA

281 cp1) were significantly reduced and its dark inducibility was lost in Deltahik8.

282 cells subjected to hypoxia, and such hypoxia inducibility was lost in truncated constructs lacking th

283 hyarrhythmias in 40% of patients: arrhythmia inducibility was not a predictor of events at follow-up

284 patients (6% of the total study population); inducibility was not tested after ablation in 4, and VT

285 Finally, with this system homogeneous inducibility was observed rapidly and with low doses of

286 NOR inducibility was restored to NorR null mutants by expres

287 tion of the RPA GP or autonomic blockade, AF inducibility was significantly inhibited.

288 Persistent AF inducibility was significantly reduced by DHA compared w

289 regional ischemia was induced and arrhythmia inducibility was tested.

290 Independent risk factors for inducibility were age at study > or =18 years (OR, 3.3),

291 electroanatomic mapping, basket catheter, VT inducibility) were performed within 1 week of PET.

292 demonstrated by a loss of Ah receptor ligand inducibility when the XRE core region (CACGCA) was delet

293 ad no statistically significant effect on AF inducibility, whereas pilsicainide plus dofetilide rende

294 t one subfragment (CRM2-A) contributes light inducibility, while another (CRM2-B) exhibits a diurnal

295 Stress response and antioxidant enzyme inducibility with exercise lead to protection against st

296 We correlated electrophysiologic inducibility with spontaneous ventricular tachycardia (V

297 e tested for basal luciferase expression and inducibility with TGFbeta, which is known to activate th

298 We correlated inducibility with the occurrence of subsequent ventricul

299 s correlates with the advent of MHC class II inducibility; with loss of YY1 binding to the promoter o

300 ricular tachycardia/ventricular fibrillation inducibility without complications.