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1 he inflammatory factors cyclooxygenase-2 and inducible nitric oxide synthase.
2 ng agents and also in cells transfected with inducible nitric oxide synthase.
3 n of IL-12, interferon-gamma (IFN-gamma) and inducible nitric oxide synthase.
4 Induction of MMP-9 expression requires inducible nitric oxide synthase.
5 IFN-gamma), tumor necrosis factor alpha, and inducible nitric oxide synthase.
6 genes, including IL-6, IL-4, IFN-gamma, and inducible nitric oxide synthase.
7 components, tumor necrosis factor-alpha, and inducible nitric oxide synthase.
8 tor R2, hypoxia-inducible factor-1alpha, and inducible nitric oxide synthase.
9 neuroprotection, presumably by counteracting inducible nitric oxide synthase.
11 (LYRM9; P = 1.97 x 10(-10)) and rs944722 in inducible nitric oxide synthase 2 (NOS2; P = 1.28 x 10(-
12 egulation of IL-1beta, TNF-alpha, IL-12, and inducible nitric oxide synthase 2 and downregulation of
14 nterleukin-6: -56%; interleukin-1beta: -42%; inducible nitric oxide synthase: -36%; tumor necrosis fa
15 the expression of pro-inflammatory enzymes: inducible nitric oxide synthase (66.7%, 65.1% and 88.0%,
18 In vitro and in vivo inhibition of iNOS (inducible nitric oxide synthase) abolished macrophage-me
19 s the induction of the inflammatory protein, inducible nitric oxide synthase, activate phase 2 cytopr
20 with sertraline resulted in the induction of inducible nitric oxide synthase; activation of endoplasm
21 contributed to nitric oxide production, only inducible nitric oxide synthase activity promoted gonoco
22 tive activation) and diminished induction of inducible nitric oxide synthase (an indicator of classic
23 d by ~40%, along with medullary induction of inducible nitric oxide synthase and a dramatic increase
24 MDSCs isolated from liver expressed reduced inducible nitric oxide synthase and arginase 1 and displ
25 ired T cell-MDSC contact and was mediated by inducible nitric oxide synthase and cationic amino acid
26 ded with maximal lung expression of mRNA for inducible nitric oxide synthase and correlated with the
27 microglial activation and expression of both inducible nitric oxide synthase and cyclooxygenase 2.
28 such as upregulation of interleukin-1 beta, inducible nitric oxide synthase and cyclooxygenase-2 in
29 ecule-1, vascular cell adhesion molecule-1), inducible nitric oxide synthase and cyclooxygenase-2, in
30 active oxygen species, nitric oxide release, inducible nitric oxide synthase and cycloxygenase-2 expr
31 overexpression led to enhanced expression of inducible nitric oxide synthase and endothelial nitric o
32 adenine dinucleotide phosphate-oxidase 2 and inducible nitric oxide synthase and enhanced lung concen
33 indac, two end-effectors of preconditioning, inducible nitric oxide synthase and heat shock protein 2
34 ity, decreased glutathione levels, increased inducible nitric oxide synthase and heme-oxygenase 1 exp
35 ity, decreased glutathione levels, increased inducible nitric oxide synthase and heme-oxygenase 1 exp
37 xide synthase isoforms, and the link between inducible nitric oxide synthase and neuronal nitric oxid
38 lay effector functions such as production of inducible nitric oxide synthase and reactive oxygen inte
40 COX)-2, matrix metalloproteinase (MMP)-9 and inducible nitric oxide synthase and the MMP-9 activity,
42 rized by cryptococcal-enhanced production of inducible nitric oxide synthase and tumor necrosis facto
43 ion and elevated expression of the cytokines inducible nitric oxide synthase and tumor necrosis facto
44 twork, Irf1; 2) suppressed the expression of inducible nitric oxide synthase and type I IFN and 3) in
45 e expression of inflammatory markers such as inducible-nitric oxide synthase and cycloxygenase-2 in t
46 ion of inflammatory markers (TNFalpha, IL-6, inducible nitric oxide synthase) and a gene for glucose
47 te colony-stimulating factor), cytotoxicity (inducible nitric oxide synthase), and host factor-derive
48 ncluding cyclooxygenase-1, cyclooxygenase-2, inducible nitric oxide synthase, and components of the N
49 A expression of tumor necrosis factor alpha, inducible nitric oxide synthase, and gamma interferon in
50 uction of arginase, reactive oxygen species, inducible nitric oxide synthase, and interleukin-10.
51 crease of matrix metalloproteinases 1 and 8, inducible nitric oxide synthase, and nuclear factor-kapp
52 gulatory macrophages that expressed IL10 and inducible nitric oxide synthase, and reduced serum level
53 ly modulating the expression of S100B, GFAP, inducible nitric oxide synthase, and thrombospondins 1 a
55 popolysaccharide-induced expression of CD14, inducible nitric oxide synthase, and transforming growth
56 anslocation to the nucleus, up-regulation of inducible nitric-oxide synthase, and nitric oxide produc
57 lammatory gene expression (cyclooxygenase-2, inducible nitric-oxide synthase, and TLR4) and inflammat
58 ted inflammatory proteins (e.g. cyclophilin, inducible nitric oxide synthase, annexins, galectin, cat
59 e induction of proinflammatory cytokines and inducible nitric oxide synthase as well as the formation
60 ection was not dependent on the induction of inducible nitric oxide synthase, as assessed by depletio
61 use of either IL-17/arginase I or IFN-gamma/inducible nitric oxide synthase axis as suppressor mecha
62 a-inducible factor-1alpha, heme oxygenase-1, inducible nitric oxide synthase, B-cell lymphoma-extra l
63 cetate extract of peel reduced expression of inducible nitric oxide synthase, but enhanced expression
64 ion of proinflammatory molecules (TNF-alpha, inducible nitric oxide synthase, chemokine (C-C motif) l
65 lecule-1, vascular cell adhesion molecule-1, inducible nitric oxide synthase, cyclooxygenase-2) and a
67 were the major chemokines transcribed (in an inducible nitric oxide synthase-dependent but not nuclea
72 L-6, aortic tumor necrosis factor-alpha, and inducible nitric oxide synthase expression and aortic in
73 was paralleled by a significant increase in inducible nitric oxide synthase expression and decreased
74 nterleukin-1beta and interferon-gamma, lower inducible nitric oxide synthase expression and lower nuc
75 synthase phosphorylation, and a decrease in inducible nitric oxide synthase expression both at the c
76 ; and reducing mitochondrial dysfunction and inducible nitric oxide synthase expression can restore a
77 evels of malondialdehyde, nitrotyrosine, and inducible nitric oxide synthase expression compared to t
78 eased expression of glomerular TNF-alpha and inducible nitric oxide synthase expression compared with
79 -kappaB, monocyte chemotactic protein 1, and inducible nitric oxide synthase expression in skin lesio
84 Rag1-/- background, microabscess formation, inducible nitric oxide synthase expression, and keratino
85 RAS blocked CD8-mediated skin inflammation, inducible nitric oxide synthase expression, and keratino
86 tion, neuronal nitric oxide synthase (nNOS), inducible nitric oxide synthase expression, and nitrite
87 aminase levels, histologic damage, increased inducible nitric oxide synthase expression, and S-nitros
88 rophage activation as evidenced by increased inducible nitric oxide synthase expression, histological
93 O-Me), RA839 prevented the induction of both inducible nitric-oxide synthase expression and nitric ox
94 d tumor necrosis factor alpha (TNFalpha) and inducible nitric-oxide synthase expression, indicative o
95 B functions in these fibroblasts to regulate inducible nitric-oxide synthase expression, which we sho
101 nflammatory" DCs, and their products, IL-20, inducible nitric oxide synthase, IL-12/23p40, and IL-23p
102 ory DC products tumor necrosis factor (TNF), inducible nitric oxide synthase, IL-23, and TNF-related
105 and dramatic up-regulation of arginase I and inducible nitric oxide synthase in MDSC, which was accom
106 appaB, as well as the NF-kappaB-induced gene inducible nitric oxide synthase in microglia and CD3(+)
107 hydroxynonenal adducts, 3-nitrotyrosine, and inducible nitric oxide synthase in the jnk2(-/-) and WT
108 inflammatory cytokines and the mRNA encoding inducible nitric-oxide synthase in both LRP1-expressing
109 production of pro-inflammatory cytokines and inducible nitric-oxide synthase induction in BV2 cells i
110 selective (1400W) and a partially selective inducible nitric oxide synthase inhibitor (aminoguanidin
111 s, intrarenal infusion of a highly selective inducible nitric oxide synthase inhibitor did not reduce
112 ydrochloride or 1400W (a nonselective and an inducible nitric oxide synthase inhibitor, respectively)
114 effects of intrarenal infusion of selective inducible nitric oxide synthase inhibitors in a large an
116 reased IL-6 (1.5 +/- 0.2-fold; p = 0.02) and inducible nitric oxide synthase (iNOS) (2.4 +/- 0.4-fold
117 besity, inflammatory input through increased inducible nitric oxide synthase (iNOS) activity causes S
119 ronal and endothelial nitric oxide synthase, inducible nitric oxide synthase (iNOS) along with a seri
120 of arginine metabolizing enzymes, including inducible nitric oxide synthase (iNOS) and arginase (ARG
123 hydroxyl radical scavenger and inhibitors of inducible nitric oxide synthase (iNOS) and cathepsin B a
124 diminished LPS-induced protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenas
125 t significantly blocked the LPS induction of inducible nitric oxide synthase (iNOS) and cyclooxygenas
126 bsequent expression of the inflammatory gene-inducible nitric oxide synthase (iNOS) and cyclooxygenas
127 Additionally, the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenas
128 on of STAT1 target genes, such as TNF-alpha, inducible nitric oxide synthase (iNOS) and cyclooxygenas
130 beta(EE)(IEC) mice expressed high amounts of inducible nitric oxide synthase (iNOS) and elevated DNA
131 een found to exhibit prolonged expression of inducible nitric oxide synthase (iNOS) and enhanced kill
132 cytokines, p53-deficient MSCs expressed more inducible nitric oxide synthase (iNOS) and exhibited gre
133 by a pathway that requires the expression of inducible nitric oxide synthase (iNOS) and generation of
134 ing endothelial nitric oxide synthase (eNOS)/inducible nitric oxide synthase (iNOS) and heat shock pr
135 of TNF and IFN-gamma increased expression of inducible nitric oxide synthase (iNOS) and increased NO
138 rate that CLIC4 is induced concurrently with inducible nitric oxide synthase (iNOS) and S-nitrosylate
139 r important innate immune molecules, such as inducible nitric oxide synthase (iNOS) and solute carrie
140 inverse correlation in the expression of the inducible nitric oxide synthase (iNOS) and the Wnt/beta-
141 ced the endothelial (eNOS) and increased the inducible nitric oxide synthase (iNOS) and tumor necrosi
142 associated both with elevated expression of inducible nitric oxide synthase (iNOS) and with genetic
144 gamma interferon (IFN-gamma), IL-1beta, and inducible nitric oxide synthase (iNOS) but not in mRNA e
145 g the mTOR complex 1 (mTORC1), HIF1alpha and inducible nitric oxide synthase (iNOS) coordinates DC me
147 death, caused mainly by enhanced microglial inducible nitric oxide synthase (iNOS) expression and NO
148 emporally related to up-regulation of tissue inducible nitric oxide synthase (iNOS) expression at the
151 ells do not block upregulation of macrophage inducible nitric oxide synthase (iNOS) expression or lim
152 endothelial nitric oxide synthase (eNOS) and inducible nitric oxide synthase (iNOS) expression were i
154 nohistochemical staining for CD86 as well as inducible nitric oxide synthase (iNOS) for M1 and CD163
155 er, elevated levels of nitric oxide (NO) and inducible nitric oxide synthase (iNOS) found within the
158 udy, we reported that Sal-1 targets cellular inducible nitric oxide synthase (iNOS) in a miRNA manner
159 med to analyze the role of NADPH oxidase and inducible nitric oxide synthase (iNOS) in a murine model
160 ), which is known to cause the expression of inducible nitric oxide synthase (iNOS) in immune-type ce
161 also inhibits the inflammatory increases in inducible nitric oxide synthase (iNOS) in mouse macropha
162 reactive nitrogen species (RNS) generated by inducible nitric oxide synthase (iNOS) in the innate res
165 and the former effect was attenuated by the inducible nitric oxide synthase (iNOS) inhibitor aminogu
167 g from sleep deprivation was reversed by the inducible nitric oxide synthase (iNOS) inhibitor, 1400 W
168 A suite of biosensors for rapid detection of inducible nitric oxide synthase (iNOS) is described.
172 IFN-gamma), tumor necrosis factor (TNF), and inducible nitric oxide synthase (iNOS) mRNA expression,
173 l to produce nitric oxide (NO) or upregulate inducible nitric oxide synthase (iNOS) mRNA following To
175 er (CBLB) injury, we examined the effects of inducible nitric oxide synthase (iNOS) on the recruitmen
176 dynia were measured in chimeric mice lacking inducible nitric oxide synthase (iNOS) or poly(ADP-ribos
178 immunosuppression and determine the role of inducible nitric oxide synthase (iNOS) produced by MDSCs
179 ess the contributions of TNF, IFN-gamma, and inducible nitric oxide synthase (iNOS) to vaccine effica
180 strates surprisingly efficient inhibition of inducible nitric oxide synthase (iNOS) transcription, an
182 -treatment, the expression of both COX-2 and inducible nitric oxide synthase (iNOS) was detected with
183 The expression of an M1 macrophage marker, inducible nitric oxide synthase (iNOS) was higher and ex
184 OS), B-cell leukemia/lymphoma-2 (Bcl-2), and inducible nitric oxide synthase (iNOS) were analyzed by
185 feron (IFN-gamma), and TNF-alpha, as well as inducible nitric oxide synthase (iNOS) were significantl
186 linked to interferon (IFN)gamma induction of inducible nitric oxide synthase (iNOS), a gene linked to
187 ge infiltration, less lesional expression of inducible nitric oxide synthase (iNOS), and lower aortic
188 molecule TNF-alpha and its receptor, MIP-2, inducible nitric oxide synthase (iNOS), and nitrite also
191 ducing enzymes, cyclooxygenase 2 (COX-2) and inducible nitric oxide synthase (iNOS), correlate with m
192 sion of inflammatory marker proteins such as inducible nitric oxide synthase (iNOS), cyclooxygenase (
193 sponses, with rapid induction of nitrite and inducible nitric oxide synthase (iNOS), followed by indu
196 ry NF-kappaB p65-responsive genes, including inducible nitric oxide synthase (iNOS), interleukin-6 (I
197 found that a nitric oxide-producing enzyme, inducible nitric oxide synthase (iNOS), is overexpressed
198 ed intracellular expression of IFN-gamma and inducible nitric oxide synthase (iNOS), known to mediate
200 f vascular endothelial growth factor (VEGF), inducible nitric oxide synthase (iNOS), nuclear factor-k
201 the absence of interferon gamma (IFN-gamma), inducible nitric oxide synthase (iNOS), or the phagocyte
202 h enough concentrations, such as produced by inducible nitric oxide synthase (iNOS), reactive nitroge
203 and cocultured in the presence or absence of inducible nitric oxide synthase (iNOS), reactive oxygen
204 lls, but not human microglial cells, express inducible nitric oxide synthase (iNOS), the objective of
205 y mediated by the enzymes arginase (Arg) and inducible nitric oxide synthase (iNOS), to pathological
206 iscovery of an interaction between Rpn13 and inducible nitric oxide synthase (iNOS), we hypothesized
207 tumor necrosis factor alpha (TNF-alpha) and inducible nitric oxide synthase (iNOS), were evaluated i
208 t, immunosuppressive factors, arginase-1 and inducible nitric oxide synthase (iNOS), were not up-regu
209 es that exacerbate local tissue damage in an inducible nitric oxide synthase (iNOS)-dependent manner.
210 onsiveness by a cell dose- and substantially inducible nitric oxide synthase (iNOS)-dependent mechani
211 udy was designed to test the hypothesis that inducible nitric oxide synthase (iNOS)-mediated lipid fr
212 conditions, LRRK2 became highly expressed in inducible nitric oxide synthase (iNOS)-positive myeloid
213 ant CD11c(+) myeloid DCs, as well as TNF and inducible nitric oxide synthase (iNOS)-producing DCs, in
232 s (r = 0.9872, P < 0.0005) and expression of inducible nitric oxide synthase (iNOS; r = 0.9986, P < 0
233 We and others have previously shown that the inducible nitric-oxide synthase (iNOS) and nitric oxide
234 fection with RSV increased expression of the inducible nitric-oxide synthase (iNOS) and nitrite conce
235 were similar in WT and mdx myotubes, whereas inducible nitric-oxide synthase (iNOS) expression was in
237 el of colitis revealed the crucial roles for inducible nitric-oxide synthase (iNOS) in regulating pat
238 nderlying mechanism of HBx regulation of the inducible nitric-oxide synthase (iNOS) pathway remains u
240 associations of critical genomic elements in inducible nitric-oxide synthase (iNOS) transcription hav
244 ctive and arginine-competitive inhibitors of inducible nitric-oxide synthase (iNOS), and 2-[2-(4-meth
245 mmatory conditions are usually attributed to inducible nitric-oxide synthase (iNOS), but the role of
247 olitis models, COG112 inhibited colon tissue inducible nitric-oxide synthase (iNOS), KC, TNF-alpha, I
248 7, and IFN-beta generation were inhibited in inducible nitric-oxide synthase (iNOS)-null macrophages.
249 was performed to determine the expression of inducible-nitric oxide synthase (iNOS), cyclooxygenase (
250 -1alpha and HIF-2alpha, leading to decreased inducible-nitric oxide synthase (iNOS), NO-production, a
251 nduction of the key antimicrobial gene Nos2 (inducible nitric oxide synthase [iNOS]) in response to l
252 tory molecules [tumor necrosis factor-alpha, inducible nitric oxide synthase, interleukin-1beta (IL-1
253 mma/lipopolysaccharide-induced expression of inducible nitric oxide synthase, interleukin-1beta, and
254 or necrosis factor alpha, interleukin-1beta, inducible nitric oxide synthase, interleukin-6, and gamm
256 ed when MDSC were treated with inhibitors of inducible nitric oxide synthase (L-NAME and NCX-4016).
257 ce to P. aeruginosa keratitis, with a higher inducible nitric oxide synthase level and a lower bacter
258 ing 2',7'-dichlorofluorescein diacetate dye, inducible nitric oxide synthase levels determined by Wes
260 ase (iNOS(-/-))-deficient mice revealed that inducible nitric oxide synthase mediates oxidation of er
261 itro, which were accompanied by induction of inducible nitric oxide synthase messenger RNA and protei
262 expressed significantly increased levels of inducible nitric oxide synthase mRNA and produced higher
263 N10021 and derived octapeptides induce iNOS (inducible nitric oxide synthase) mRNA in VEC and nitrate
264 , CD8beta, gamma interferon (IFN-gamma), and inducible nitric oxide synthase (NOS2) (an effector mole
266 e identify the metalloproteinase ADAMTS1 and inducible nitric oxide synthase (NOS2) as therapeutic ta
268 increased expression of interleukin (IL)-12, inducible nitric oxide synthase (NOS2), and major histoc
270 myeloid cells are phenotypically similar to inducible nitric oxide synthase (NOS2)- and tumor necros
272 novel diflavin oxidoreductase 1 (NDOR1), and inducible nitric-oxide synthase (NOS2A), in addition to
273 ffect on the expression of interferon-gamma, inducible nitric oxide synthase or tumor necrosis factor
274 s tumor necrosis factor-alpha (P = 0.04) and inducible nitric oxide synthase (P = 0.02) in skin biops
275 aB and endothelial nitric oxide synthase/Akt/inducible nitric oxide synthase pathways were assessed b
276 1(+) CD11b(+) CD11c(Lo-Int) MAC3(+) iNOS(+) (inducible nitric oxide synthase-positive) inflammatory d
280 tion across an activated endothelium and for inducible nitric oxide synthase production upon HGF stim
281 the volume of the ischemic lesion as well as inducible nitric oxide synthase production were signific
282 duction of antibacterial nitric oxide (i.e., inducible nitric oxide synthase), production of prostagl
283 ndicated by a reduction in the expression of inducible nitric-oxide synthase, production of nitric ox
284 LPS-induced tumor necrosis factor alpha and inducible nitric-oxide synthase promoter activation.
286 ory mediators, including Nos2 (which encodes inducible nitric oxide synthase), Ptgs2 (which encodes c
287 arotid stent delivery of adenovirus encoding inducible nitric oxide synthase resulted in significant
288 ype as determined by high arginase-1 and low inducible nitric oxide synthase staining in rodent tissu
289 gh small-molecule inhibitors of arginase and inducible nitric oxide synthase, suggesting a novel ther
290 inflammatory cytokine tumor necrosis factor, inducible nitric oxide synthase, the M1 activator interf
291 the expression of proinflammatory proteins (inducible nitric oxide synthase, tumor necrosis factor-a
292 the expression of proinflammatory proteins (inducible nitric oxide synthase, tumor necrosis factor-a
293 6, IL-10, endothelial nitric oxide synthase, inducible nitric oxide synthase, type 1 heme oxygenase,
294 ndothelial nitric oxide synthase uncoupling, inducible nitric oxide synthase upregulation, and methyl
296 helial expression of Nos2, the gene encoding inducible nitric oxide synthase, was elevated in the abs
297 ired for the insertion of cellular heme into inducible nitric oxide synthase, we extensively characte
298 thermore, activation of a phagosomal enzyme, inducible nitric oxide synthase, which is necessary for
300 ene [EGR-1], interleukin [IL]-6, IL-1ss, and inducible nitric oxide synthase) within the reperfused i
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