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1 in which endogenous cohesin can be silenced inducibly.
3 estion using a mouse model in which we could inducibly ablate PAX interacting (with transcription-act
5 nary disease (COPD); however, when Mig-6 was inducibly ablated in adult mice (Mig-6(d/d)), the lungs
10 hich MyoD or its nonacetylatable version was inducibly activated in mouse embryonic fibroblasts deriv
13 t3) which acts as a dominant negative, or an inducibly active Stat3-gyraseB chimera (Stat3-GyrB).
14 pulation of genetically modified cells to be inducibly amplified, thereby averting the risks associat
18 in which a dominant negative Nur77 mutant is inducibly and specifically expressed in mouse endothelia
22 ponse to calcium influx, Shc, Grb2, and Sos1 inducibly associate with a 180-kDa tyrosine-phosphorylat
24 n to bind to a GDP-exchange factor (C3G) and inducibly associate with the focal adhesion complex.
25 the carboxyl-terminal SH2 domain of PI3K to inducibly associate with the full-length SHP-1 protein.
28 rough the scaffold molecule Bcl10, which was inducibly associated with JNK2 and served as a JNK-inter
33 a Ste20-related serine-threonine kinase that inducibly associates with the adaptors SLP-76 and Gads a
35 binding mammalian gene product, is expressed inducibly at high levels and enterobactin-secreting resp
36 lathrin-binding protein fragment ("hook") is inducibly attached to an "anchor" protein at the plasma
37 kappaB subunits Rel A, NF-kappaB1, and c-Rel inducibly bind the TNF response element; these proteins
39 precipitation experiments revealed that BRG1 inducibly binds to the CIITA promoter despite the absenc
40 romoter in an ATM-dependent manner, and IRF7 inducibly binds to the endogenous retinoic acid-inducibl
41 romotes recruitment of Rac1 to IQGAP1, which inducibly binds to VEGFR2 and which, in turn, is associa
42 ral of these inducible Oct1 targets are also inducibly bound by Oct4 in embryonic stem cells followin
43 The majority of the identified loci are heat-inducibly bound by yeast HSF, and the target genes encod
44 ces that included heat shock elements, which inducibly bound heat shock factor 1, TATA-like elements,
45 utively by human granulocytes and testis and inducibly by keratinocytes, is modulated by an energy-de
47 llergic airway inflammation, we developed an inducibly CD28-deleting mouse strain or alternatively us
48 itope-tagged proteins were constitutively or inducibly coexpressed in protoplasts with amiRNA candida
49 pitope-tagged proteins are constitutively or inducibly coexpressed with individual amiRNA candidates
54 RIIA demonstrated that Fc gamma RIIA is also inducibly coupled to the serine/threonine and lipid kina
57 that maintain differentiated cells, here we inducibly delete the histone demethylase LSD1/KDM1A in a
60 e-Lox-based mouse model in which Chkl can be inducibly deleted from somatic epithelial cells in the a
61 sgenic mouse in which Mef2a, -c, and -d were inducibly deleted in adult nestin-expressing NSPCs and t
63 and metabolizing enzymes have been deleted, inducibly deleted, and knocked in as tagged or altered r
65 rythropoiesis in a cell-autonomous manner by inducibly deleting Trim28 exclusively in hematopoietic c
67 tion, we developed a genetic method that can inducibly deplete targeted proteins and that mimics thei
69 C12 cell lines in which levels of GSH can be inducibly down-regulated via doxycycline induction of an
70 yme in de novo glutathione synthesis, can be inducibly downregulated in catecholaminergic neurons, in
71 he ETV1 promoter is used to specifically and inducibly drive Cre recombinase in ICC as a strategy to
72 sis directly, LNCaP cells were engineered to inducibly express a constitutively activated form of the
73 ts DNA replication, we generated cells which inducibly express a constitutively active allele of RB (
75 so demonstrate that 3T3-derived cells, which inducibly express a dominant-negative BRG-1, arrest by P
77 ogical setting, we implemented a strategy to inducibly express active MLK3 in the preformed acini of
81 riant, we generated stable cell lines, which inducibly express DeltaNp73alpha, DeltaNp73beta, and var
82 99 lung carcinoma and U118 glioma cells that inducibly express Dkk-1 under a tetracycline-regulated p
83 we established stable Jurkat cell lines that inducibly express dominant active (DA) or dominant negat
84 scle-specific gene expression, in cells that inducibly express dominant negative versions of Brahma (
85 on, we introduced Mitf into fibroblasts that inducibly express dominant negative versions of the SWI/
86 ere we have developed an efficient method to inducibly express double-stranded RNA hairpins and demon
88 s we used immortalized cortical neurons that inducibly express either a full-length tau isoform (T4)
89 n of EGFP-S was examined in cell lines which inducibly express either wild-type CK2 holoenzyme or a C
92 tracycline-regulated NIH-3T3 cell lines that inducibly express either wild-type Pak1, a kinase-dead,
94 we used adenovirus-mediated gene transfer to inducibly express FLAG-tagged mouse NSMase-2 in primary
95 his, we have developed novel cell lines that inducibly express FLAG-tagged versions of either the pho
96 e-regulatable RT4 schwannoma cell lines that inducibly express full-length merlin with mutations at t
100 reated a HEK293-based cell culture system to inducibly express individual interferon-stimulated genes
101 "knock-in" Cre-estrogen receptor alleles to inducibly express K-RasG12D in CC10(+) epithelial cells
102 xpression, we have generated cell lines that inducibly express mutant forms of the BRG1 or BRM ATPase
104 rebellar ataxia 17 (SCA17) knockin mice that inducibly express one copy of mutant TATA box binding pr
106 several MCF7 adenocarcinoma cell lines that inducibly express p73 or p53 under a tetracycline-regula
107 stablished several groups of cell lines that inducibly express p73 under a tetracycline-regulated pro
109 ough the use of stable MCF7 cell lines which inducibly express short hairpin RNA targeting HDAC2, we
110 In U2OS and NCI-H1299 cells engineered to inducibly express the dominant-negative mutant E2F-1 (1-
111 ted cells as well as in clones engineered to inducibly express the mutant protein upon exposure to do
113 generated several groups of cell lines that inducibly express various p53 mutants using a tetracycli
114 ing VACV recombinants that constitutively or inducibly express VETF subunits and RAP94 with affinity
116 gene expression profiles in cell lines that inducibly express wild-type and mutant Vpr proteins.
119 y in HeLa cells and in HeLa cell lines which inducibly expressed a dominant interfering mutant of dyn
120 antly reduced the cell surface expression of inducibly expressed alpha2B-AR and arrested the receptor
122 f leaf development, juvenile leaf cells that inducibly expressed Arabidopsis ABP1 prematurely advance
123 ctin turnover by monitoring incorporation of inducibly expressed beta-actin-GFP in adult mouse hair c
130 ermediary factor 1 beta (TIF1beta) as a gene inducibly expressed early during myeloid differentiation
132 tains the adenovirus E1 and E2a region genes inducibly expressed from separate glucocorticoid-respons
135 rodimeric transcription factor containing an inducibly expressed HIF-1alpha subunit and a constititut
136 rodimeric transcription factor containing an inducibly expressed HIF1alpha subunit and a constitutive
137 Ligand binding analyses confirmed that human inducibly expressed hsp-70-bound 25-OHD3 with approximat
139 h a constitutively active form of Akt can be inducibly expressed in adult skeletal muscle and thereby
141 s that are constitutively expressed, MCL1 is inducibly expressed in cells that are recently exposed t
142 stabilized (t1/2 approximately 3.5 hr) when inducibly expressed in either quiescent or proliferating
144 s type 1 (HSV-1) UL12 open reading frame was inducibly expressed in Escherichia coli and purified wit
145 Together, these results show that Cyr61 is inducibly expressed in granulation tissues after woundin
146 ator (Aire), a transcriptional regulator, is inducibly expressed in human and mouse tumor keratinocyt
147 ated variant of androgen receptor (TC-AR) is inducibly expressed in LNCaP, an androgen-dependent cell
149 this study, we demonstrate that gV-sPLA2 is inducibly expressed in mouse and human macrophages (M) a
151 haracterized inhibitor IkappaB delta is also inducibly expressed in response to inflammatory stimuli.
152 ost probably has a mononuclear Fe center, is inducibly expressed in roots as well as in leaves of Che
153 hese studies demonstrate that a RASSL can be inducibly expressed in several mouse tissues and used in
159 Stat5 protein by C-terminal truncation, and inducibly expressed it in an IL3-dependent cell line.
160 asion of host cells has been disrupted using inducibly expressed oligonucleotide external guide seque
161 ppaB) and induces cell death, whereas TNFR2, inducibly expressed on endothelial cells and on TECs by
162 families members, ICOS, PD-1, and BTLA, are inducibly expressed on T cells, and they have important
163 nerated multiple cell lines in which LSD1 is inducibly expressed or knocked down and found that LSD1
164 stitutively and p101 as a protein forming an inducibly expressed PI3Kgamma, (iii) differences in basa
167 xpression of c-Maf in myeloid cell lines, we inducibly expressed the c-Maf cDNA in 2 bipotent human m
168 ntify the bona fide target genes of Hog1, we inducibly expressed the spontaneously active variant Hog
169 cells and costimulates effector T cells, are inducibly expressed under harmful conditions, such as ma
170 of A6, we established a HeLa cell line that inducibly expressed VACV-A6, which allowed us to constru
172 we generated a double transgenic mouse that inducibly expresses a ligand-independent constitutively
173 ogeny, we have used a transgenic line, which inducibly expresses an inhibitor of BMP signaling, Noggi
176 addition, a recombinant vaccinia virus that inducibly expresses F9, like a previously described L1 m
177 a BALB/c-3T3 cell line (termed p27-47) that inducibly expresses high levels of this protein, we show
179 by p27Kip1, we constructed a cell line that inducibly expresses p27Kip1 upon addition of isopropyl-1
181 FosB by using a bitransgenic mouse line that inducibly expresses the protein in the NAc and dorsal st
182 ected insect Sf9 cell line (Sf9(VSV-G)) that inducibly expresses the VSV-G protein upon infection wit
183 his question, we generated Tet-On A431 cells inducibly expressing a desmoplakin (DP) mutant lacking t
185 nd mitotic catastrophe in osteosarcoma cells inducibly expressing a p27Kip1 mutant (termed p27K) that
186 blished several stable cell lines capable of inducibly expressing a p53 mutant alone, wild-type p53 a
187 nalysis of Rab1 purified from a yeast strain inducibly expressing AnkX revealed that this small GTPas
188 in confluence, fibroblasts constitutively or inducibly expressing BAD persisted in S phase, continued
191 21 overexpression in vivo, BHK21 cell clones inducibly expressing human p21 (Tet-p21) driven by the t
193 otypic cultures derived from transgenic mice inducibly expressing oncogenic beta-catenin and/or PIK3C
194 n adult tissue, we developed transgenic mice inducibly expressing p14(ARF) (human ortholog of murine
195 ion of p21(WAF1/CIP1) (i.e., in Jurkat cells inducibly expressing p21(WAF1/CIP1) under the control of
196 o DNA was confirmed in a 16HBE14o- cell line inducibly expressing PKC delta-CAT under the tet-off sys
198 stable human embryonic kidney 293 cell lines inducibly expressing the wild-type or kinase-defective d
203 ein (EGFP) and expressed this fusion protein inducibly in a HEK 293-based cell line to avoid possible
204 g transgenic mice overexpressing calcineurin inducibly in forebrain neurons, we now provide evidence
205 n which two dominant oncogenes are expressed inducibly in human cells using the lac repressor/lac ope
208 Several TLRs are expressed constitutively or inducibly in the intestine, and contribute to immune def
209 hic growth, we created mice where Myc can be inducibly inactivated, specifically in adult myocardium.
211 ural activity could then be specifically and inducibly increased in the hM(3)D(q)-expressing neurons
214 flammatory cytokines, the deubiquitinase A20 inducibly interacts with the regulatory molecules TAX1BP
215 nerated multiple cell lines in which ECT2 is inducibly knocked down and found that ECT2 knockdown tri
216 acquires its gain-of-function, mutant p53 is inducibly knocked down in the SW480 colon cancer cell li
217 cells, in which endogenous mutant p53 can be inducibly knocked down, to identify mutant p53 target ge
221 6R-yellow fluorescent protein (YFP) mouse to inducibly label nestin-expressing stem cells and their p
223 ped a mouse Hes1(CreERT2) knock-in allele to inducibly mark Hes1(+) cells and their descendants.
224 ivity compared to erythromycin A against the inducibly MLS (macrolide, lincosamide, and streptogramin
227 Several recombinant vaccinia viruses that inducibly or constitutively express an enhanced green fl
229 n which endogenous mutant R273H/P309S can be inducibly or stably knocked down, whereas a small interf
231 deed, derivatives of the HC11 cell line that inducibly overexpress an exogenous PKC alpha or ectopic
233 l-TRE-CXCL1 double-transgenic (Tg) mice that inducibly overexpress CXCL1 under the control of the ast
235 ality, in which a cloned "reference" gene is inducibly overexpressed in a set of mutant strains carry
237 RKO and MCF7 cell lines in that GPR87 can be inducibly overexpressed or knocked down by a tetracyclin
238 ates the activity of the p53 family, STX6 is inducibly overexpressed or knocked down in various cell
241 ng a noninvasive pharmacogenetic approach to inducibly perturb neuron activity postnatally, and ask i
243 ng TCR ligation, all of the CD3 ITAMs become inducibly phosphorylated and associate with the ZAP-70 p
244 l by an inhibitory subunit IkappaB, which is inducibly phosphorylated by an IkappaB kinase complex an
247 n essential component of the ribosome and is inducibly phosphorylated following mTOR activation in eu
250 guanine nucleotide exchange factor Vav1 was inducibly phosphorylated in a Syk-dependent manner in ce
251 vely associated with CD120a (p55) and become inducibly phosphorylated in macrophages in response to T
256 mice with serine-to-alanine mutations at the inducibly phosphorylated serine 310 alone or at conserve
257 ic labeling experiments indicate that Syk is inducibly phosphorylated to an even greater extent on se
258 response to TGF-beta, specific Smads become inducibly phosphorylated, form heteromers with Smad4, an
260 Here we report that the PPM1G phosphatase (inducibly recruited by nuclear factor kappaB [NF-kappaB]
261 gnificant fraction of human CD2 molecules is inducibly recruited into lipid rafts upon CD2 cross-link
264 ls, focal adhesion kinase (FAK) and PI3K are inducibly recruited to raft-associated membrane domains.
265 well as other members of the MCM family, is inducibly recruited to Stat1 target gene promoters in re
266 TCR signaling, the adaptor protein Bcl10 is inducibly recruited to the CARD11 scaffold protein as pa
267 actors ATF-2, c-jun, Egr-1, and Sp1 are also inducibly recruited to the TNF-alpha promoter in vivo, a
270 in which sustained transgene expression was inducibly regulated, both specifically and homogeneously
273 le in editing, we generated cell lines which inducibly replaced band IV protein with an enzymatically
275 testing (MIC, 8 microg/ml), one isolate was inducibly resistant to oxacillin (MIC of 16 microg/ml af
278 icient U251 glioblastoma cells engineered to inducibly restore PTEN upon exposure to doxycycline.
279 drug-induced HSF1 is constitutively but not inducibly serine-phosphorylated, whereas heat shock-indu
282 conditions under which beta-catenin might be inducibly stabilized in vivo would be inhibitory for T c
283 utively active Akt transgene, which could be inducibly targeted to the vascular endothelium using the
284 phage- and neutrophil-rich inflammation when inducibly targeted, in a transgenic fashion, to the adul
288 ned, the Src family kinases Fyn and Blk were inducibly tyrosine phosphorylated and activated by recep
289 s, such as ZAP-70, SLP-76, and pp36, are all inducibly tyrosine phosphorylated following TCR ligation
291 and 80 kDa exist and that these proteins are inducibly tyrosine phosphorylated in the response to sev
292 Despite this, the SLP-76 adapter protein was inducibly tyrosine phosphorylated, and both the Ras-mito
295 lenic B cells and in B cell lines capable of inducibly undergoing immunoglobulin SR on their chromoso
296 proteins that happen to be constitutively or inducibly unstable, and in this capacity it plays a regu
298 a 97-kDa cytosolic protein (p97), associates inducibly with SHP-2 upon cytokine stimulation and const
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