ライフサイエンスコーパス: induction

1 his signal does not require canonical ligand induction.

2 iogenesis) is required for its VEGF-mediated induction.

3 ve delivery, stillbirth and post-term labour induction.

4 epression of general translation and latency induction.

5 ic epithelial cells (TEC) for effective Treg induction.

6 HO-1-mediated hepatoprotection and autophagy induction.

7 caled up without compromising the asymmetric induction.

8 CC) and in an experimental model of lung TLS induction.

9 king group complete response (CR) rate after induction.

10 structures that persist for up to 2 y after induction.

11 anging at varying intervals after senescence induction.

12 cription factor ERG, a prerequisite for DLL4 induction.

13 cell (BMC) engraftment and promote tolerance induction.

14 activation, mTORC1 inhibition, and autophagy induction.

15 nonsensitized patients receiving anti-IL-2R induction.

16 of the devalued saccharin solution after CTA induction.

17 hose of WKY rats and produced more IL-17F on induction.

18 lting in receptor crosslinking and apoptosis induction.

19 acilitate coincidence detection during t-LTP induction.

20 ationship between cell proliferation and iCM induction.

21 Slco1a4) and hepatocyte-to-blood transporter induction (Abcc4, Abcc3).

22 antagonist provides full rescue of both LTP induction and dopamine release during optogenetic activa

23 nduction of gene expression during papilloma induction and during wound healing.

24 ion and nuclear exclusion, leading to Baf60c induction and insulin-independent AKT activation.

25 estigate mechanisms and determinants of PVEM induction and its potential role in commotio cordis-indu

26 e using a hybrid approach that combines rule induction and machine learning.

27 Th17 cell development, JunB is required for induction and maintenance of Th17 effector responses in

28 ata from 13 randomized multicenter trials of induction and maintenance regimens in first-line FL ther

29 rate that IL-27 is a potent regulator of ROS induction and may be a novel therapeutic target.

30 nsplant and pretransplant covariates between induction and no induction groups.

31 sensor kinase, prevented decorin-evoked TFEB induction and nuclear localization.

32 pment involves conserved basic mechanisms of induction and patterning, combined with a more plastic p

33 ry organ segregation by antagonizing lateral induction and promoting commitment to the non-sensory fa

34 The abrogation of Cho1 induction and PSS activity by a CHO1 UASINO mutation sup

35 etter understanding of processes involved in induction and resolution of chronic inflammation and tol

36 Y10F sensitized the cancer cells to anoikis induction and resulted in attenuated cell invasion and e

37 nificant hypoventilation occurred during the induction and start bronchoscopy following hypoventilati

38 factors Pho4 and Pho2 are required for gene induction and survival during phosphate starvation.

39 The increased Th17 induction and the correspondingly 10-fold higher CT B su

40 the integration plasmid was much lower after induction, and which produced improved titres of apidaec

41 ium oxide coating removal; 2) surface change induction; and 3) residual biocompatibility toward osteo

42 Pap1-dependent genes still relied on stress induction, another subset of stress-responsive genes was

43 Mesoderm induction begins during gastrulation.

44 of no clinically relevant differences after induction between groups.

45 nt findings regarding sexual dimorphism, bud induction, branching morphogenesis and cellular differen

46 Eosinophils were dispensable for myocarditis induction but were required for progression to DCMi.

47 ose of Hi1a (2 ng/kg) up to 8 h after stroke induction by occlusion of the middle cerebral artery mar

48 This hypoxia-specific apoptosis induction by YC-1 involved excessive reactive oxygen spe

49 10% of the mean dose used for recombination induction, caused adverse effects to the testis and to t

50 They were treated with 3-drug induction chemotherapy (vincristine, dactinomycin, and d

51 After induction chemotherapy 163 of 189 (84.0%) underwent defi

52 Early response to induction chemotherapy is an important prognostic factor

53 l vertebrate species indicates that mesoderm induction continues after gastrulation in neuromesoderma

54 ion experiments further indicate that R-loop induction correlates to transcriptional pausing.

55 Ultimately, this approach to in vivo Treg induction could also enable novel therapies for transpla

56 Type VII collagen induction did not generate anti-type VII collagen autoan

57 cal requirements for rejection and tolerance induction differ between various organs.

58 Growth induction displaces ciliary Inpp5e and accumulates phosp

59 ing neutrophil influx and cytokine/chemokine induction during active menstruation.

60 3) inactivation of a factor needed for Fshb induction (e.g. growth differentiation factor 9).

61 d both cancer-inhibition and differentiation-induction effects of ZNF750.

62 Our aim was to determine the role of end-of-induction (EOI) minimal residual disease (MRD) assessmen

63 in the identification and stratification of induction failure in patients with pediatric acute lymph

64 elapse in nearly all (70 [89%] of 79) XR-NTX induction failures.

65 There were no associations between induction, graft loss, and incident cancer.

66 ansplant covariates between induction and no induction groups.

67 s as measured by flow cytometry on day 28 of induction I.

68 clerosis complex 2 (TSC2) inhibits lipophagy induction in DENV-infected cells and decreases viral rep

69 has been found to have a broad role in gene induction in diverse cellular responses, particularly th

70 We found that systemic acquired resistance induction in female inflorescences mainly involves accum

71 ow that BCR signaling can activate EBV lytic induction in freshly isolated B cells from peripheral bl

72 als exploring the efficacy of oral tolerance induction in infancy for the prevention of FA.

73 plementation, and gene editing, that haploid induction in maize (Zea mays) is triggered by a frame-sh

74 FGF-mediated PM induction in NMPs functions in tight coordination with c

75 ing, and is necessary for PI3K/AKT signaling induction in response to MPhi activation.

76 e of ABA receptor genes revealed a different induction in response to soil flooding (CsPYL5) or droug

77 c resonance imaging (MRI)) to detect melanin induction in SKMEL28 human melanoma cells, following inh

78 Our results indicate that germ layer induction in the zebrafish tailbud is not a simple conti

79 thaliana), very little is known about floral induction in tulip.

80 a single, compact speck and rapid cell-death induction in vivo requires a full-length ASC.

81 Plants were examined poststress induction in vivo, and changes in the concentration leve

82 At a time corresponding to peak LCN2 induction in wild-type (WT) mice injected with LPS, Lcn2

83 eurons recapitulated MMP activation and t-SP induction (increase in AMPA currents in MSNs).

84 Standard strategies for transgene induction involve the use of viral vectors prone to sile

85 Here the authors show that cis P-tau induction is a feature of several different forms of TBI

86 ing ChIP-seq), we show that synergistic gene induction is achieved by assisted loading of STAT3 on ch

87 Alemtuzumab induction is beneficial in reducing hospital length of s

88 Rapid induction is key to control virus infection, whereas pro

89 G4B to control LC3 processing.Upon autophagy induction, LC3 is cleaved by the protease ATG4 and conju

90 ER stress induction led to a reduced ECD protein level, but this e

91 icited similar results suggesting that IL-34 induction may be a general response to neuronal stress i

92 nterferon and mild pro-inflammatory cytokine induction may qualify as vaccine adjuvants.

93 s highlight an unexpected ligand-independent induction mechanism and suggest that constitutive NOTCH3

94 h time cells become IFN responsive, allowing induction of a broad spectrum of ISGs by IFN signaling.

95 measure upregulation of basophil CD203c and induction of a CD63(hi) basophil population can be condu

96 us of Spc110, or its inactivation during the induction of a DNA lesion, generate abnormal oscillatory

97 In addition, induction of a dormant state by the inhibition of MYC, r

98 Here we show that the induction of a myokine, irisin, improves kidney energy m

99 ssion of pro-inflammatory markers and by the induction of a pro-regenerative environment.

100 l regulators and find a role for HSF1 in the induction of a subset of heat shock-induced readthrough

101 This difference may explain the enhanced induction of Abs when targeting Ag to cDC1 using hXCL1 a

102 After induction of acute respiratory distress syndrome by hydr

103 far been limited because of the insufficient induction of adaptive immune responses.

104 tes, SGBS adipocytes showed not only greater induction of adipogenic gene expression during different

105 mmune complexes (IgG-IC) via breast milk and induction of allergen-specific regulatory T (T reg) cell

106 H50Q, G51D or A53E alphaS fibrils displayed induction of alphaS inclusion pathology that increased a

107 kg), or high dose ketamine (1.0 mg/kg) after induction of anaesthesia, before surgical incision.

108 contributions of nsp14 ExoN activity in the induction of and resistance to the innate immune respons

109 are describing a novel pathway that mediates induction of angiogenesis in response to TGF-beta1.

110 ation of tissue-resident macrophages and the induction of anti-inflammatory and tissue repair genes i

111 etion or anergy of antigen-specific T cells; induction of antigen-specific regulatory T cells; or imm

112 While induction of antiviral type I interferons (IFNs) is the

113 eckpoint both contributed to the synergistic induction of apoptosis and proliferation inhibition in A

114 he most potent effects on growth inhibition, induction of apoptosis, and delay of acquired resistance

115 T laser power (2 W/cm(2)) to achieve maximal induction of apoptosis.

116 a mechanism to promote BOK accumulation and induction of apoptosis.

117 The vascular endothelium is critical for induction of appropriate lineage differentiation in orga

118 Cocaine induces the rapid induction of Arc and its nuclear accumulation in striata

119 demonstrated that eIF2alphaP is required for induction of ATF4 protein synthesis in vivo in erythroid

120 We demonstrated IBDV induction of autophagy as a significant increase in punc

121 These findings indicate that induction of autophagy, and removal of ataxin-3 protein,

122 Immune control can be facilitated by induction of autophagy, as well as by polyploidization o

123 Finally, induction of BCRP expression in JEG3 and BeWo cells was

124 cell migration, SMAD7 degradation, EMT, and induction of beta-catenin, and all of these pathways are

125 ical analyses demonstrated that SepA-related induction of biofilm accumulation resulted from enhanced

126 at the hepatitis C virus (HCV) pandemic, and induction of broadly neutralizing monoclonal antibodies

127 f both genes was elevated in obese mice, and induction of Cadm1 in excitatory neurons facilitated wei

128 administering specific molecules to prevent induction of capsid-specific CD8(+) T cells.

129 During induction of cardiac arrest, the right ventricle dilated

130 JB12 knockdown by siRNA led to the induction of caspase processing but not the unfolded pro

131 romotes hyphal morphogenesis, sufficient for induction of caspase-1-mediated macrophage lysis.

132 by blockade of nuclear FOXO4 degradation and induction of caspase-dependent apoptosis.

133 l ester (ABAGE) synthesis, and to a moderate induction of catabolism (CsCYP707A, an ABA 8'-hydroxylas

134 A expression of IL-27 was important to their induction of CD25(+) lymphocyte activation gene 3 (LAG3)

135 MiR-630 mimics blocked TGFbeta1 induction of CDH2 in normal and IPF fibroblasts, and ant

136 Induction of cell death was cell autonomous and required

137 enteroids and human IEC lines, we found that induction of cell stress alters the cytoskeleton in IECs

138 s are induced by mitogens and accompanied by induction of cell-cycle markers, including phosphorylati

139 Further analysis revealed the induction of cellular senescence in zebrafish embryos ov

140 deficiency in donor CD4(+) T cells, with the induction of cGVHD ameliorated by BCL6 deficiency and co

141 L-18R/MyD88 pathway as a crucial element for induction of cognate Th1 responses against an important

142 after helminth infection or in the gut after induction of colitis.

143 lographic model for the planar assembly, the induction of curvature into the RSV CA hexamer lattice a

144 On one hand, mTOR inhibition blunts the induction of cyclin-dependent kinase (CDK) inhibitors (C

145 Normal responses following induction of cystitis by cyclophosphamide were also obse

146 p process including direct tumor cell lysis, induction of cytotoxic or apoptosis-sensitizing cytokine

147 Following the MIP, there was a robust induction of depressed mood in the control group, but no

148 nd, in a subset of immunized animals, in the induction of detectable NAb, supporting that the identif

149 ovides molecular pathway predictions for the induction of different transcriptional programmes in LCs

150 ve immune responses that are critical to the induction of disease, persistence of inflammation, and a

151 PK/ERK pathway mirrors the rapid and dynamic induction of DLL4 transcription and that this pathway is

152 Therefore, the cooperative induction of DNA replication stress and damage by ATR in

153 These methods involve the induction of double-strand breaks at endogenous loci fol

154 of encephalitogenic T cells and promote the induction of EAE during the age window of young adulthoo

155 The induction of EBI3 protein expression in mouse NK cells i

156 Loss of Gfi1 resulted in premature induction of effector genes and the transcription factor

157 Acinar Sec23b deletion results in induction of ER stress and increased apoptosis in the pa

158 ambient IL-6 was sufficient to suppress the induction of expression of the transcription factor Foxp

159 ATP and AMP from cancer cells in response to induction of extrinsic apoptosis by death receptors or i

160 e converse effect, linking MTOR signaling to induction of fiber cell differentiation by TGFbeta.

161 Interestingly, fasting induction of fibroblast growth factor 21 in liver was at

162 s expression, suggesting roles for TLR7/8 in induction of fibrocytes in HCV infection.

163 le for postsynaptic kainate receptors in the induction of functional and structural plasticity in the

164 t protein (GFP)-knock-in mice revealed rapid induction of gene expression during papilloma induction

165 Induction of gene expression under hypoxia requires tran

166 y transcription factor EB (TFEB) through the induction of genes involved in lysosomal biogenesis and

167 ression of AtCGS in RNAi seeds triggered the induction of genes operating in the SMM cycle of rosette

168 vates the Nrf2-Keap 1 pathway leading to the induction of genes through antioxidant response elements

169 Induction of GLI2DeltaN enhanced the beta-catenin-depend

170 RA2A activation promotes the transcriptional induction of glycolytic enzymes via ERK- and Akt-depende

171 significantly reduces dexamethasone-mediated induction of GR target genes and GRE-driven reporter act

172 with fungal burden and hyphal length but not induction of GT biosynthetic genes.

173 We show here that the induction of gut dysbiosis triggers the development of s

174 in intramuscular oxygen levels, resulting in induction of HIF-1alpha.

175 In contrast to re-induction of HLA class-I by interferons, HDAC inhibitors

176 , cAMP-independent signals contribute to the induction of hyphal responses.

177 Of note, induction of IBTKalpha and the UPR, along with inhibitio

178 the monocytic cell line THP-1 results in an induction of IFN-stimulated genes in these cells.

179 as carriers of bacteria responsible for the induction of IgE sensitization to microbial antigens.

180 ) Th2 cells, but it also participates in the induction of IL-13 receptors and miR-126a expressed on/i

181 breast tumor cells, which is crucial for the induction of IL-13(+) Th2 cells, but it also participate

182 There was also induction of IL-17 and its promoting cytokines in total

183 ysate (TMH) enhanced innate immunity through induction of IL-1beta and COX-2 expression.

184 Among the strongest changes was also induction of IL6 in resistant cells and the expression w

185 KSHV-transformed cells, resulting in chronic induction of IL6, IL1beta, and IL18.

186 in transient nasopharyngeal colonization and induction of immunoglobulin G and immunoglobulin A to al

187 tural protein 1 (NS1) of WNV antagonizes the induction of interferon beta (IFN-beta) by interacting w

188 aling' here) was needed to prevent premature induction of interferon-gamma (IFN-gamma) expression in

189 hUGT1/Car(-/-) neonatal mice because of ROS induction of intestinal UGT1A1.

190 This allowed induction of ischemia in a specific cortical region of c

191 an innate immunoregulatory mechanism through induction of itBreg cell differentiation, which takes pl

192 s nearly completely abolished HAC1 splicing, induction of KAR2, PDI1, and beta-galactosidase reporter

193 2014 to compare perinatal mortality between induction of labour at 39, 40, and 41 weeks of gestation

194 n of pregnancy to either spontaneous labour, induction of labour, or caesarean section at a later ges

195 ons of neutrophils via, at least partly, the induction of lactoferrin to present a potential therapy

196 This is required for the induction of lipophagy, but not basal autophagy, in DENV

197 miRNA activity in neurons in response to the induction of long-term depression.

198 of parallel fiber-Purkinje cell synapse and induction of long-term plasticity (LTP) in M1, leading t

199 nergic receptors (betaARs) enhances both the induction of long-term potentiation (LTP) in hippocampal

200 in vitro Furthermore, miR-718 regulates the induction of LPS tolerance in macrophages.

201 ell adhesion by activating integrins and the induction of membrane protrusions by activating Rac1 and

202 d-forward loop to activate MYC signaling via induction of miR-33b.

203 l surface receptors, suggesting that vaccine induction of multiple NAbs with distinct neutralization

204 response to phenylephrine at 18 hours after induction of murine endotoxic shock.

205 d show a role for Crebbp inactivation in the induction of Myc expression.

206 nted subunit vaccines were successful in the induction of NAbs and T cell responses in guinea pigs.

207 antibodies against V3 can interfere with the induction of NAbs, but there are good arguments in favor

208 , suggesting a role for paracrine factors in induction of neuronal apoptosis.

209 Here, we report that induction of neuronal autophagy enhances BACE1 turnover,

210 vesicular glutamate transporter eat-4/VGLUT, induction of neuropeptide expression, changes in axonal

211 migration persistence through a synergistic induction of NF-kappaB-dependent MMP1 expression in canc

212 in primary macrophages leads to an increased induction of NLRP3 by LPS, which is also accompanied by

213 Induction of oral tolerance to haptens is an efficient w

214 CD3 cells with hypertonic NaCl inhibited the induction of osmoregulated genes, including Nr1h4, which

215 e protein (DC-STAMP) plays a key role in the induction of osteoclast (OC) cell fusion, as well as DC-

216 d to an enhancement of the DNA-damage driven induction of p21 and PIG3.

217 cells was dispensable for cytokine-dependent induction of pattern recognition receptor, cell adhesion

218 approach to pest management through indirect induction of plant resistance.

219 Retinal break associated with induction of posterior vitreous detachment was the most

220 sly unknown signatures of infection, such as induction of potassium channels and amino acid transport

221 Concurrent induction of potent cellular and humoral immune response

222 in synthesis and initiate cell death through induction of pro-apoptotic pathways.

223 ck bacterial cell wall breakdown, limits the induction of pro-inflammatory signals required for optim

224 stores nucleosomal dynamics, promotes normal induction of protective stress genes, and rescues stress

225 is provides a molecular basis to explain the induction of RAS-RAF association by RAF inhibitors, as w

226 Induction of recall responses within white adipose tissu

227 opular transgenic method for controlling the induction of recombination by Cre at a specific time and

228 d tissues of the gut are specialized for the induction of regulatory cells, which are directly respon

229 ers of neutralizing antibodies (NAbs), their induction of robust CD8 T cells has largely been unrepor

230 The induction of ROS activates the Nrf2-Keap 1 pathway leadi

231 al-derived MPs from ACS patients reduced the induction of senescence.

232 lls emerge in bone marrow chimeric mice upon induction of skin inflammation by topical treatment with

233 The induction of SMARCA2 in response to EZH2 inhibition is r

234 However, the mechanisms regulating induction of specific CREB/CRTC1-dependent genes during

235 fferentially regulated by epidermal cytokine induction of specific IRF-controlled pathways.

236 Moreover, induction of stress marker genes and ROS-scavenging enzy

237 ing significantly reduced neuroinvasiveness, induction of strong adaptive immunity, and protection of

238 ferred DGKzeta(-/-) T cells relied partly on induction of sustainable host T-cell immunity.

239 ough dendritic cells (DCs) are vital for the induction of T-cell responses, the DC subpopulations tha

240 The induction of t-SP during cued reinstatement depends on a

241 mulation of PTMs are driving factors for the induction of tau-mediated neuronal damage.

242 bsets that occur following trauma, including induction of Th17-type CD4 T cells, reduced T-bet expres

243 he myriad molecular pathways that govern the induction of TH2 differentiation and the critical role o

244 Gene expression studies revealed that induction of the cell cycle inhibitor Cdkn1a was respons

245 n vivo Mevastatin also reversed FPP-mediated induction of the GR target, the transcription factor c-M

246 served in patient fibroblasts after chemical induction of the Hh pathway.

247 that glucose levels influenced the extent of induction of the inflammatory T cell subset in vitro tha

248 ted that the SIR was facilitated through the induction of the NFkappaB pathway.

249 By assessing the signals responsible for induction of the Notch ligand delta-like 4 (DLL4) in end

250 We propose that the induction of the post-transcriptional suppressor DND1 sy

251 Induction of the transcription factor Klf4 in differenti

252 vitro findings, specifically the significant induction of the Ucp1 gene and UCP1 protein expression i

253 Induction of the UPR is linked to decreased ATG16L1 stab

254 ed endoplasmic reticulum calcium levels, and induction of the UPR.

255 ith all other treatment groups due to direct induction of thermal necrosis in the tumor core and effi

256 Accordingly, the induction of these nAb responses acquired after serial D

257 ns rely on regulatory T cells, we found that induction of tolerance to proteins in aluminum hydroxide

258 uggests that PRC2 acts as a brake to prevent induction of transcribed genes on the inactive X chromos

259 ptionally active p53-and correlates with the induction of transcription of target genes such as CDKN1

260 We observe massive induction of transcriptional readthrough, both in levels

261 We found induction of tumor suppressor protein, p53, and apoptosi

262 riven mast cell activation are necessary for induction of type 2 immunopathology and aspirin sensitiv

263 f antigenic variability and the preferential induction of type-specific immune responses with limited

264 allenge, subjects with atopy displayed rapid induction of upper airway symptoms, an enrichment of ILC

265 eptors, supporting their role in directional induction of vasculogenesis.

266 ophage cells in the lungs and airways, early induction of virus specific antibodies, reduced levels o

267 expressions and ROS production but promoted inductions of inflammatory cytokines, compared to wild t

268 itellogenin-like proteins in male organisms, inductions of Na(+)K(+)/ATPases, and strong inhibitions

269 nses obtained in contaminated sites included inductions of vitellogenin-like proteins in male organis

270 r to be driven by distinctions in DNA damage induction or repair capacity.

271 Here we report data for the eight-cycle induction period, up to week 24.

272 riglyceride accumulation following different induction periods and using various tissue culture plate

273 a visual analog scale following the sad mood induction procedure (MIP).

274 at novel edits in MTL lead to a 6.7% haploid induction rate (the percentage of haploid progeny versus

275 However, it was also found that the HSP72 induction rate was slightly decreased by increasing the

276 lity of the cartilage formed under different induction regimens.

277 uiring treatment; had received, at most, two induction regimens; and had achieved stable disease or b

278 g DC phenotype and optimal methods for their induction remain an intense area of research.

279 ferentially expressed genes and magnitude of induction/repression.

280 pecifically induced by excess iron, and this induction requires PerR.

281 to date of antibacterial prophylaxis during induction therapy for pediatric ALL and the first to inc

282 The use of induction therapy in pediatric heart transplantation has

283 In subgroup analyses, induction therapy may be associated with improved surviv

284 Despite initial response to induction therapy, nearly 50% of high-risk neuroblastoma

285 on in response to pattern-triggered immunity induction through interaction with poly(A)-binding prote

286 D8(+) DCs play a requisite role in tolerance induction through interactions with NKT cells.

287 LKB1 and AMPKalpha, which regulate autophagy induction through their kinase activities.

288 Pretreatment with CcnE1-siRNA reverted CcnE1 induction to baseline levels of healthy mice, which was

289 that explore the efficacy of oral tolerance induction to other common food allergens and that focus

290 Future work should focus on facilitating induction to XR-NTX and on improving treatment retention

291 Oral tolerance induction was enhanced in mice lacking expression of IL-

292 the development of steatosis, lipogenic gene induction was significantly increased in WT mice, includ

293 Such an induction was suppressed by the concomitant presence of

294 No-induction was the least effective and most costly option

295 ell contact and specific cell type in ORMDL3 induction were examined by transwell assay and depletion

296 cteristics, and sputum cytology after sputum induction were examined.

297 ets to the inferior vena cava wall after DVT induction were reduced in MC-deficient mice.

298 Alemtuzumab induction with desensitization led to nearly equivalent

299 results show that after hRSV infection, HO-1 induction with metalloporphyrin cobalt protoporphyrin IX

300 ell inserts following isotropic chondrogenic induction with transforming growth factor beta to set up