ライフサイエンスコーパス: infection

1 a discussion of the current animal models of infection.

2 dynamics during fungal development and plant infection.

3 estations characteristic of M. gallisepticum infection.

4 latory role of IFN-induced proteins in HIV-1 infection.

5 3 integrin prevents outside-in signaling and infection.

6 cells are defective in controlling Listeria infection.

7 ggesting a unique neuronal response to viral infection.

8 y plays unappreciated accessory roles during infection.

9 the cytokine IL-17 in response to Plasmodium infection.

10 he best available animal models to study RSV infection.

11 to the adverse conditions it encounters upon infection.

12 f whom 3085 (91.4%) had laboratory-confirmed infection.

13 )infection but might also signify occult HBV infection.

14 egulated in latent vs. replicative states of infection.

15 antiretroviral therapy (ART) during chronic infection.

16 .2% (95% CI 28.1%-30.4%) after mixed-species infection.

17 and IFNlambda2) and become resistant to ZIKV infection.

18 uce the rate of reactivation of latent virus infection.

19 ne/Cefotaxime against highly pathogenic MRSA infection.

20 ociated with chronic hepatitis B virus (HBV) infection.

21 to the severity and ultimate outcome of the infection.

22 cts on the clinical outcome of P. falciparum infection.

23 phages to limit lung damage during influenza infection.

24 ld be further explored to reduce the risk of infection.

25 f innate/inflammatory responses in SIVmac239 infection.

26 t of SAH, but can increase susceptibility to infection.

27 n the dimerized form of LukAB during natural infection.

28 defervescence and convalescent stages of the infection.

29 sues and cell populations over the course of infection.

30 ts expressed by the spirochete during murine infection.

31 emoval and reimplantation during the initial infection.

32 human immunodeficiency virus type 1 (HIV-1) infection.

33 llows inference on the likely source of each infection.

34 f the regulatory cascade that causes chronic infection.

35 significantly amplified after Dengue-2 virus infection.

36 ctivating the ER stress pathway during viral infection.

37 of the microbiota reduces host resistance to infection.

38 dditional survival costs when hosting double infections.

39 P. berghei P47 in Anopheles gambiae mosquito infections.

40 commonly identified organisms in bloodstream infections.

41 ns as well as to systemic and oral bacterial infections.

42 (+) (SHS-Tg(+)) mice failed to resolve these infections.

43 ht also have viral or intracellular pathogen infections.

44 cteristic of reactivation of lifelong latent infections.

45 patients (4%) had life-threatening or fatal infections.

46 l therapy to treat complicated urinary tract infections.

47 e mechanism responsible for the clearance of infections.

48 y and mortality due to healthcare-associated infections.

49 thogen that causes rare but life-threatening infections.

50 ate defence against primary alphaherpesvirus infections.

51 nd a major cause of persistent and recurrent infections.

52 ibility pattern of external ocular bacterial infections.

53 ide but no vaccine is available against CVA6 infections.

54 develop new antimicrobials for mycobacterial infections.

55 nd hospital attendance for respiratory tract infections.

56 ease outcomes during intracellular bacterial infections.

57 ed average of probabilities for simultaneous infections.

58 eviruses are responsible for chronic cardiac infections.

59 e clinically relevant asexual blood stage of infection(1).

60 5.7, 95% CI 5.5-5.8), particularly non-AIDS infections (10.8, 9.8-12.0) and liver disease (3.7, 3.3-

61 minority are nonpermissive because the virus infection aborts before its completion.

62 produced during human cytomegalovirus (HCMV) infection activate the antiviral kinase protein kinase R

63 s have declared the recent Zika virus (ZIKV) infection an epidemic and a public health emergency of g

64 ized infants were tested for influenza virus infection and 1 tested positive.

65 E virus (HEV) is regarded as a self-limiting infection and anti-HEV antibodies seem to protect agains

66 ies are often inadequate to detect bacterial infection and are not specific for living bacteria.

67 s and serves as an innate link between viral infection and B cell immunity.

68 amphibians are associated with both parasite infection and chemical contaminants, but that their rela

69 s in the inflammatory contexts of both acute infection and chronic autoimmunity in mice.

70 t the SIP signaling pathway is active during infection and contributes significantly to GAS pathogene

71 gher peripheral blood viral loads in primary infection and greater changes in viral diversity generat

72 respond to inhaled pathogens, thus favoring infection and inflammation that may eventually lead to t

73 t combine iron interventions with control of infection and inflammation.

74 f CD8(+) T cells prevented recovery from MRV infection and led to lethality in infected animals, wher

75 during the inflammatory response to control infection and limit the detrimental effects of inflammat

76 ic CD8 T cells home to the site of recurrent infection and participate in viral clearance.

77 use the model recapitulates human poliovirus infection and poliomyelitis, it can be used to study pol

78 Our findings indicate that HIV infection and replication rely on a limited set of host-

79 HIV-1 establishes chronic infection and stimulates vigorous immune responses in th

80 Six patients (5%) developed invasive fungal infections and 5 patients (4%) had life-threatening or f

81 failure, cytomegalovirus, and/or adenoviral infections and transplant-related mortality at 1 year we

82 e 9.5 million (69.3%) pregnancies at risk of infection (and 53.4% [16.3 million/30.6 million] of all

83 965, (2) who lacked a prior diagnosis of HCV infection, and (3) who lacked prior documented anti-HCV

84 APC after respiratory syncytial virus (RSV) infection, and its inhibition leads to exaggerated immun

85 eria (ie, brain metastases, minimum age, HIV infection, and organ dysfunction and prior and concurren

86 to variation in test cost, prevalence of HSV infection, and random variation to study assumptions.

87 n important role in sepsis, pneumonia, wound infections, and cystic fibrosis (CF), which is caused by

88 immune response to prevent serious bacterial infections, and represent a significant advancement towa

89 dyslipidemia, drug abuse, and opportunistic infections; and lifestyle are risk factors for HIV-assoc

90 nce interval {CI}, .76-.95]) and respiratory infection (aOR, 0.82 [95% CI, .75-.90]) and remained sig

91 We test the hypothesis that sex-biases in infection are related to variation in multilayer contact

92 Bloodstream infections are a leading cause of morbidity and mortalit

93 Severe human adenovirus (HAdV) infections are an increasing threat for immunosuppressed

94 Because repeated or persistent infections are correlated with serious complications in

95 options for chronic Hepatitis E Virus (HEV) infections are limited and immunological determinants of

96 tudies have suggested that acute respiratory infection (ARI) and nonsteroidal anti-inflammatory drugs

97 s a model antibiotic and Helicobacter pylori infection as a model disease.

98 stic regression with PCR-confirmed influenza infection as the outcome and vaccination status defined

99 ificantly increased resistance to Plasmodium infections as well as to systemic and oral bacterial inf

100 defect frequently presenting with recurrent infections, as well as associated immune dysregulation m

101 ow but escalating risk of severe M. chimaera infection associated with heater-coolers with cases in a

102 arriers nor at the species-level, suggesting infection-associated, short-term, within-host selection

103 However, detection of H. pylori infection at any point up to age 6.5 years was associate

104 oral symptoms, as well as be a reservoir for infection at other sites of the body.

105 ion was associated with lower risk of device infections at 5 years.

106 ed exposure-response relationship for Vibrio infections at a threshold of 16 degrees C revealed a rel

107 Moreover, we estimated that the infection attack rates were 78.0% (95% confidence interv

108 lymphocytic and nonlymphocytic cells during infection, autoimmunity or neoplasms.

109 tory-confirmed viral upper respiratory tract infections based on parent-collected nasal swabs over th

110 resolved, and chronic hepatitis B virus (HBV)infection but might also signify occult HBV infection.

111 f TIM-1 expression significantly reduced HCV infection but not HCV RNA replication.

112 vering the viral genome into the host during infection, but how the genome is organized and delivered

113 2, are essential for hepatitis C virus (HCV) infection, but the underlying mechanism and relevance to

114 become an immunology hotspot, implicated in infections, but also in a diverse array of diseases such

115 The absence of LIMP reduces initial mosquito infection by 50%, impedes salivary gland invasion 10-fol

116 milieu that supports host protection during infection by fine-tuning NF-kappaB activity, suggesting

117 impairment of endocytosis affects productive infection by prion strains 22L and RML.

118 cal for the control of West Nile virus (WNV) infection by regulating type I IFN (IFN-I) response.

119 epletion of T cells prevented nasopharyngeal infection by S. pyogenes, but not by Streptococcus pneum

120 J mice are extremely susceptible to systemic infection by Salmonella Typhimurium because of loss-of-f

121 Lytic infection by the Epstein-Barr virus (EBV) poses numerous

122 trait loci for germination and resistance to infection by the fungus Albugo laibachii, isolate Nc14.

123 ng 17 patients (8%) served as controls, with infections by either hepatitis A virus or hepatitis B vi

124 e successfully cleared spontaneous bacterial infections by PND22, the SHS-exposed Scnn1b-Tg(+) (SHS-T

125 to HIV envelope (Env) develop during natural infection can help guide the rational design of an HIV v

126 cular pathological epidemiology to S. aureus infection can usher in a new era of highly focused perso

127 Many viral infections cause host shutoff, a state in which host pro

128 as T cell exhaustion, occurs during chronic infections caused by a variety of pathogens, from persis

129 ion is characterized by fungal and bacterial infections caused by impaired generation of TH17 cells;

130 all patients with chronic cavitary pulmonary infections, chronic invasive and granulomatous rhinosinu

131 levels in cells infected with cagA-positive infections compared to cells infected with either cagA-n

132 sociated with lower rates of invasive fungal infections compared with placebo or no intervention in c

133 risk of mortality provides evidence that GBS infection contributes to NE.

134 hly pathogenic avian influenza A(H5N1) virus infection, detected through population-based active surv

135 es into existing HIV infection, tuberculosis infection, diabetes, chronic respiratory disease, and bl

136 ke infections with other parvoviruses, HBoV1 infection did not activate the apoptotic or necroptotic

137 viously indicated that the effect of malaria infection during pregnancy on the risk of low birthweigh

138 La in HEK 293 T cells increased Sendai virus infection efficiency, decreased IFN-beta, IFN-lambda1, a

139 ntially regulated according to the source of infection, enriched for IFN signaling and antigen presen

140 Interestingly, we showed that the number of infection events per cell during cell-free HIV-1 infecti

141 resulted in an increased number of abortive infection events, including bursting of ITs and a reduct

142 and antioxidative responses to S Typhimurium infection, eventually leading to cell death.

143 However, the no-infection fish dramatically suppressed tapeworm growth r

144 suppressed tapeworm growth relative to high-infection fish, and parasite size was intermediate in F1

145 To accurately capture the force of infection (FOI) between districts, we compared 6 models

146 ction events per cell during cell-free HIV-1 infection follows a negative-binomial distribution, and

147 imed to trace the geographic origin of HIV-1 infection for migrants who inject drugs and to investiga

148 of virologically confirmed Zika virus (ZIKV) infections from Southeast Asia, ZIKV infection was gener

149 Importantly, the proportion of EV-A71 infection generally increased with age which showed rapi

150 that individuals with a streptococcal throat infection had elevated risks of mental disorders, partic

151 s and observed fetal malformations following infection has been missing.

152 e contribution of CD19 in the context of CNS infections has not been evaluated.

153 Mouse models of T. cruzi infection have been used to study heart damage in Chagas

154 Viral infections have been proposed to elicit pathological pro

155 eiving insulin therapy had greater hazard of infection (hazard ratio, 2.18; 95% CI, 1.90-2.51) but no

156 dely deployed for detection of P. falciparum infection; however, these tests often miss cases of low-

157 although the precise mechanisms whereby HIV infection impedes successful T cell-mediated control of

158 activation of HSC for liver fibrosis in HCV infection.IMPORTANCE HCV-associated liver fibrosis is a

159 s for isolated enterectomy included systemic infection in 11, gastrointestinal bleeding in 1, and sev

160 ven a single, uncoated particle can initiate infection in a cell.IMPORTANCE The pathways by which a v

161 ive drug delivery to treat gastric bacterial infection in a mouse model using clarithromycin as a mod

162 hampered by a scarcity of models that mimic infection in a physiologically relevant, cellular contex

163 parasitemia levels during the first week of infection in all three mice strains before resolving spo

164 onreactivating, latent-like or a replicative infection in CD34(+) hematopoietic progenitor cells, we

165 ose N. gonorrhoeae and Chlamydia trachomatis infection in certain populations by nucleic acid amplifi

166 sthesia converts an asymptomatic rhabdovirus infection in Drosophila to one that is lethal.

167 iron deficiency, iron treatment, and malaria infection in endemic areas; the heightened impact of com

168 t Enterococcus (VRE), leading to bloodstream infection in hospitalized patients.

169 pes virus with tropism for B lymphocytes and infection in immunocompetent individuals is typically as

170 nervous system abnormalities, and timing of infection in infants with confirmed Zika virus during pr

171 f Mtb during the acute and chronic phases of infection in mice through physiologic functions apart fr

172 tutive activation is required for gonococcal infection in mice.

173 lus ribavirin for the treatment of acute HCV infection in participants with chronic human immunodefic

174 e impact of viremia and risk factors for CMV infection in pediatric LT recipients managed with gancic

175 Since the significantly higher levels of SIV infection in SLOs occurred with a massive accumulation o

176 symptomatic rhesus monkeys that had survived infection in the absence of or after treatment with cand

177 cated in the temporary control of lentiviral infection in the brain.

178 -infected ticks did not develop a persistent infection in the murine host.

179 mportant to control A. actinomycetemcomitans infection in the murine oral cavity and to prevent subse

180 iptome sequencing showed a high incidence of infection in the NTSR Peldon population.

181 herapy among patients with a replicating HDV infection in the Swiss HIV Cohort Study.

182 ction is the most common chronic blood-borne infection in the United States and a leading cause of mo

183 nd neutrophils, and protected mice from MRSA infection in two model systems.

184 can neutralize or enhance Zika virus (ZIKV) infection in vitro, their contribution to ZIKV infection

185 and kill bacteria during at least 4 hours of infection in vitro.

186 fection in vitro, their contribution to ZIKV infection in vivo remains unclear.

187 target pathogens to their preferred sites of infection in vivo.

188 y and low incidence of avian influenza virus infections in humans, the immune correlates of protectio

189 vel strategies for enhancing host defense to infections in newborns.

190 y epithelial damage to protect the host from infections in patients with chronic rhinosinusitis with

191 ut does not routinely result in communicable infections in the new host.

192 acquisition of HIV and sexually transmitted infections in women.

193 ELISPOT, in pregnant women with primary HCMV infection, in association with avidity index and DNAemia

194 e healthcare costs associated with bacterial infections, including the implementation of local and na

195 We showed that MAV-1 infection increases enzymatic activity of two key MMPs k

196 Gonococcal infection induced a significant increase in secreted MMP

197 Zika virus infection induced detectable Dengue cross-reactive serum

198 We found that DENV infection induced metabolic dysregulation and inflammato

199 We discovered that RSV infection induces a complex of bromodomain containing 4

200 Here, we show that BDV infection induces expression of key enzymes of the kynur

201 However, it remains unclear how infection initially becomes latent.

202 Chronic norovirus infection is an emerging challenge in the immunocompromi

203 Rapid identification of bacterial infection is essential to ensure early appropriate admin

204 Hepatitis C virus (HCV) infection is the most common chronic blood-borne infecti

205 The spread of many respiratory infections is determined by contact patterns between inf

206 risks for food security posed by rumen fluke infection, it is imperative that we develop a better und

207 r lifelong persistence, involving productive infection, latency, and intermittent reactivation.

208 ents in the United States suffer from dental infections, leading to pulp necrosis, arrested tooth-roo

209 Recently, we demonstrated that HCV infection leads to monocyte differentiation into polariz

210 The tests for diagnosing latent tuberculosis infection (LTBI) are limited by a poor predictive value

211 Here we show that during bacterial infection, lysozyme is rerouted via secretory autophagy,

212 Using three mouse infection models, we show that the SIP signaling pathway

213 ly ill adults with infection-positive versus infection-negative systemic inflammation.

214 During infection, Neisseria gonorrhoeae senses and responds to

215 ent of cells with purified VacA proteins and infection of a mouse model, we show that H. pylori dereg

216 Infection of bone is a severe complication due to the va

217 Our data indicate that Ct infection of ESC impairs decidualisation and alters chem

218 By in vitro infection of gastric epithelial cells with wild-type and

219 cation of the role of the JNK pathway in VZV infection of neurons reveals potential avenues for the d

220 Specifically, Asian-lineage ZIKV infection of pregnant women's blood led to an exacerbate

221 Influenza viral infections often lead to increased mortality in older pe

222 Rooms from which a patient with infection or colonisation with a target organism was dis

223 ration through tissues can enable control of infection or mediate inflammatory damage.

224 In most natural infections or after recovery, small numbers of Leishmani

225 Fatal infections or sepsis were significantly more common in t

226 sed eosinophil activity, recurrent pulmonary infections, or both, as evident by the concomitant prese

227 to examine trends in icidence of bloodstream infection over time.

228 METHODS AND People with and without HIV infection participating in HSV-2 natural history studies

229 -tailed macaques as a model of M. genitalium infection, persistence, and immune evasion.

230 an infrequent cause of periprosthetic joint infection (PJI).

231 icrobiological diagnosis of prosthetic joint infections (PJI).

232 During the liver stage of a malaria infection, Plasmodium parasites are targeted by the auto

233 tory cytokine responses to LPS and bacterial infection, POP2 transgenic mice are more resistant to ba

234 d to discriminate critically ill adults with infection-positive versus infection-negative systemic in

235 Concurrent helminth infection potently inhibits T cell immunity; however, wh

236 pp65 than to IE-1 or IE-2, whereas in remote infection pp65-, IE-1-, and IE-2-specific T cells were d

237 nation tests capable of detecting markers of infection present during different stages of infection (

238 outbreaks from medical equipment and provide infection prevention recommendations.

239 ial matrix and has roles in inflammation and infection processes, mitochondrial ribosome biogenesis,

240 ce in complications, including urinary tract infection rates, between those using single or multi-use

241 se (Mn), a common dietary supplement, alters infection remain unexplored.

242 The effect of persistent EBV infection remained significant even after adjustment for

243 sm and relevance to other viruses or in vivo infections remained unknown.

244 ears of observation [PYO]), 371 HCV incident infections resulted in an overall incidence of 22.6 per

245 ter intravenous infection, while respiratory infection results in virus replication in the lung.

246 A low %DHR(+) value strongly predicts infection risk in X-linked CGD carriers, and the carrier

247 between estimated bottleneck size and donor infection severity, as measured by temperature.

248 position to S. aureus expression of clfA and infection severity.

249 Severe Perkinsea infections (SPI) were systemic and led to multiorganic f

250 However, despite being often overlooked, the infection spread due to contaminated equipment, vehicles

251 With bacterial contamination, surgical site infections (SSI) are a serious complication that can res

252 an increasing number of skin and soft tissue infections (SSTIs) in Denmark and other European countri

253 ctively address highly pathogenic and lethal infections stemming from bacterial, fungal, and viral or

254 ith any of four curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and

255 and cell wall gene families, while divergent infection strategies are linked to radiations of lineage

256 many important tissues that may be sites of infection such as the lungs and soft tissues.

257 ied several previously unknown signatures of infection, such as induction of potassium channels and a

258 ecific" or related to a specific diagnosis), infections, such as polyomavirus-associated nephropathy,

259 erity of other acute lower respiratory tract infection symptoms, duration of abnormal peak flow, anti

260 nsgenic mice are more resistant to bacterial infection than wild-type mice.

261 e-associated stomatitis is a common candidal infection that may give rise to painful oral symptoms, a

262 In pregnant women with primary infection, the cultured ELISPOT assay detected a higher

263 After initial infection, the virus establishes latent reservoirs in se

264 A total of 283 patients had a serious infection; the incidence rates with 95% confidence inter

265 iotics are prescribed appropriately to treat infections, there continue to be a large number of inapp

266 well as resting T-cells, SAMHD1 blocks HIV-1 infection through this dNTP triphosphohydrolase activity

267 tes the probability of lysogeny for variable infection times by a time-weighted average of probabilit

268 odel representing the course of an influenza infection to explore the possibility of extracting NAI d

269 causative link was established linking viral infection to herbicide resistance, transcriptome sequenc

270 gy, epidemiology, clinical manifestations of infection, treatment, and public health significance of

271 gration of fungal diseases into existing HIV infection, tuberculosis infection, diabetes, chronic res

272 Dengue virus infection typically causes mild dengue fever, but, in se

273 d the development of postkeratoplasty fungal infection using corresponding corneal tissue.

274 infection present during different stages of infection (viral nonstructural protein 1 and immunoglobu

275 (ZIKV) infections from Southeast Asia, ZIKV infection was generally mild.

276 The proportion of patients with genital infections was greater with empagliflozin than placebo i

277 770 health-care-associated infections were reported in 726 children and adolescents

278 the liver of these animals after intravenous infection, while respiratory infection results in virus

279 FA classifications to identify patients with infection who are at elevated risk of poor outcomes.

280 l therapy (ART) to eliminate pediatric HIV-1 infection will require the characterization of maternal

281 Infection with a recombinant pH1N1 virus encoding these

282 logical phenotypes, including survival after infection with coxsackievirus B3.

283 while decreasing viral replication following infection with FHV, whereas treatment with the KATP chan

284 Chronic infection with hepatitis C virus (HCV) is one of the mai

285 ogene 141 (RNA5SP141), bound to RIG-I during infection with herpes simplex virus 1 (HSV-1).

286 Indeed, following infection with Listeria monocytogenes, DNA-PKcs-deficien

287 Infection with low-dose A/X31 H3N2 led to prolonged dete

288 ian rousette develops subclinical productive infection with MARV but is refractory to EBOV.

289 glected tropical disease caused by a chronic infection with parasitic helminths of the genus Schistos

290 on of neutrophils under conditions mimicking infection with S. aureus conferred responsiveness to IL-

291 ) bacteria are a novel, potent tool to study infection with the pathogen in vitro and in vivo and the

292 the expanded cerebral organoids to show that infection with Zika virus impairs cortical growth and fo

293 Chronic infections with hepatitis C virus (HCV) and HIV are high

294 Unlike infections with other parvoviruses, HBoV1 infection did

295 y identified 1.9-85.9% of confirmed Shigella infections, with sensitivity decreasing over time (p=0.0

296 Eleven of the 434 patients had another infection within 6 months, but only 4 of them were manag

297 showed CD4(+) T cell loss but recovered from infection without lethality.

298 ere community-acquired and hospital-acquired infection worldwide.

299 is a common cause of health care associated infections worldwide.

300 tors CD4 and CCR5, that are required for HIV infection yet are dispensable for cellular proliferation