ライフサイエンスコーパス: infection with

1 of 10-del ZIKV caused no mortality, whereas infections with 10 IFU of wild-type ZIKV were lethal.

2 atified HIV prevalence showed early onset of infection with 11.8% (95% CI 7.3-18.4) of MSM aged 18-19

3 s deaths worldwide were in children with HIV infections, with 31 000 (36%, 19 000-59 000) in the WHO

4 f transmission was healthcare-acquired (HAI) infection, with 4 generations of HAI transmission.

5 s and immune responses induced after an i.v. infection with a Brazilian ZIKV clinical isolate (HS-201

6 increased morbidity and mortality following infection with a common human enterovirus.

7 gical RNA species recognized by RIG-I during infection with a DNA virus are largely unknown.

8 e highlight the molecular mechanism by which infection with a dsRNA virus results in necroptosis.

9 ons of a viral non-structural protein during infection with a medically important arthropod-borne vir

10 DV vaccine strain Onderstepoort succumbed to infection with a more recent wild-type strain, indicatin

11 tion of HIV infection, and only two cases of infection with a multidrug-resistant virus have been rep

12 By contrast, systemic infection with a murine cytomegalovirus (MCMV) engineere

13 ng viral genomes bound by protein VII during infection with a mutant lacking early region E4.

14 Infection with a PT-deficient strain induced severe pulm

15 with uninfected individuals, those with HIV infection with a recent biomarker of more severe immune

16 Infection with a recombinant pH1N1 virus encoding these

17 Infection with a reovirus strain that targets this splic

18 immunity to HSV-2 may be protective against infection with a second strain.

19 ulin G (IgG) ELISAs combined can detect ZIKV infection with a sensitivity of 95% and specificity of 6

20 glycoprotein expression plasmid followed by infection with a vesicular stomatitis virus expressing t

21 st the ability of these MAbs to protect from infection with a vesicular stomatitis virus expressing t

22 nificantly larger lesions at later stages of infection, with a more pronounced inflammatory infiltrat

23 ectivities, from background levels to modest infection, with a small number of Envs from some patient

24 sed with Bcl6 in Tfh cells after acute viral infection, with a temporal decline in T-bet in the wanin

25 anded immunity to protect against subsequent infections with a different HCV genotype.

26 eb 23, 2017, 1220 laboratory-confirmed human infections with A H7N9 virus were reported in mainland C

27 h ZIKV with previous DENV and secondary DENV infections with a sensitivity of 87.5% and specificity o

28 msters, pathology resulting from intravenous infection with adenoviruses is caused mostly by replicat

29 Since the first evidence of human infection with an animal influenza virus, in 1958, 16 di

30 mountain gorilla population was suspected of infection with an EBV-like virus based on serology and i

31 emale, but not male, mice when compared with infection with an isogenic hla deletion mutant.

32 Indeed, curing HCV infection with an oral medication is now reality.

33 A case was defined as infection with an outbreak strain in which illness onset

34 te to the induction of necroptosis following infection with an RNA virus.IMPORTANCE An appreciation o

35 nucleolar pattern of B23 was unchanged upon infection with an SBV recombinant mutant with NSs lackin

36 uld discriminate between acute and past B19V infection, with an excellent discriminatory capacity whe

37 athology associated with acute or persistent infections with an unrelated virus.

38 week 12 (SVR12) in patients with genotype 1b infection with and without cirrhosis who received coform

39 of cccDNA under conditions mimicking chronic infections with and without antiviral therapy, which pre

40 No increase in breakthrough infections with antibiotic-resistant organisms was seen,

41 cious, they suggest that treatment of common infections with antibiotics in infancy is unlikely to be

42 currence of fever, a common manifestation of infection, with ASD risk.

43 In vaccine-eligible men, the prevalence of infection with at least 1 HPV strain targeted by the HPV

44 Intranasal infection with attenuated RABV prolonged the survival of

45 n (ACT) is a critical factor in establishing infection with B. pertussis and acts by specifically inh

46 host-pathogen interaction that is central to infection with B. pertussis and other Bordetella species

47 (+)) accumulated in the lungs of mice during infection with B. pertussis and significantly expanded t

48 st reinfection and memory induced by natural infection with B. pertussis.

49 blood cell transfusions acquired babesiosis infection with Babesia divergens-like/MO-1 organisms and

50 We found that provisioning increased infection with bacteria, viruses, fungi and protozoa (i.

51 ection models, but their activity in chronic infection with biofilm models has not been previously in

52 tration of all three phases of disease after infection with Borrelia burgdorferi.

53 e site typically between 7 and 14 days after infection with Borreliella burgdorferi.

54 to understand the role of domain 5 in PRRSV infection with both type 1 and type 2 viruses, pigs were

55 Infection with both viruses resulted in breakpoint-depen

56 of TNF-alpha, IL-6, and IL-8 upon subsequent infection with Burkholderia pseudomallei and Salmonella

57 rticularly those with cardiac valve disease, infection with C. burnetii can cause a life-threatening

58 sed survival compared to wild-type mice upon infection with C. neoformans This increase in survival c

59 -gamma and interleukin-17A production during infection with C. rodentium However, upon CD4 T cell tra

60 sufficient to provide enhanced protection to infection with C. rodentium.

61 Infection with Candida albicans, disseminated disease, p

62 Mixed infection with capsulated Pg augmented alveolar bone los

63 While bNAbs potently antagonize infection with cell-free virus, inhibition of HIV-1 tran

64 Strategies to prevent active infection with certain double-stranded DNA (dsDNA) virus

65 Syrian hamsters are susceptible to infection with certain human adenoviruses, and the patho

66 An example is infection with Chlamydia trachomatis (Ct), which is the

67 After intravaginal infection with Chlamydia, CCR7-deficient mice displayed

68 BACKGROUND & AIMS: Nosocomial infections with Clostridium difficile present a consider

69 logical phenotypes, including survival after infection with coxsackievirus B3.

70 Infection with cytomegalovirus (CMV) can elicit a CD8(+)

71 Persistent infections with cytomegalovirus (CMV) differentially aff

72 Adaptive immune responses protect against infection with dengue virus (DENV), yet cross-reactivity

73 at memory T cell responses elicited by prior infection with DENV or vaccination with tetravalent deng

74 at memory T cell responses elicited by prior infection with DENV recognize ZIKV-derived peptides and

75 f these, 7 had chronic symptomatic norovirus infection with diarrhea (noro group), and 8 had diarrhea

76 pients who had symptomatic chronic norovirus infection with diarrhea were asked to participate in thi

77 monocytes, particularly during pregnancy, on infection with different lineages of ZIKV.

78 Source of infection, with different causative organisms and tempor

79 Starting infections with different segment combinations, we found

80 ies, Taiwan, and Hong Kong have caused human infections, with differing severity and frequency.

81 ific and sensitive assay showed asymptomatic infection with Ebola virus was uncommon despite high exp

82 onate documented to have survived congenital infection with Ebola virus.

83 In vitro, about 20 days after infection with EBV lacking functional EBNA3A and EBNA3C,

84 Here, we show that, in humans, primary IBV infection with either lineage induces HA-specific antibo

85 into cutaneous melanoma lesions during acute infection with either virus, after a cleared vaccinia vi

86 Infection with emerging pathogens may alter the thermal

87 iency (SPAD) revealed in adulthood by severe infections with encapsulated bacteria.

88 were reported for 342 health-care-associated infections, with Enterobacteriaceae being the most frequ

89 Cross-reactions due to infection with environmental mycobacteria and/or bacille

90 e strong age dependency of neonatal systemic infection with Escherichia coli K1 can be replicated in

91 f control subjects, independent of source of infection, with eukaryotic initiation factor 2 signaling

92 critical for protection of the host against infection with extracellular microbes, such as the bacte

93 treated for recurrent Clostridium difficile infection with fecal microbiota transplantation (FMT) at

94 d that blood cells are uniquely resistant to infection with FeLV-B due to the activity of cellular en

95 be important in protection against zoonotic infection with FeLV.IMPORTANCE Domestic exposure to gamm

96 while decreasing viral replication following infection with FHV, whereas treatment with the KATP chan

97 However, breakthrough infections with fungal pathogen Aspergillus fumigatus ar

98 ockdown (kd) enhances mosquito resistance to infections with fungi, bacteria, and Plasmodium parasite

99 as a virulence factor in coaggregated mixed infection with Fusobacterium nucleatum (Fn).

100 findings demonstrate that mountain gorilla's infection with GbbLCV-1 could provide valuable informati

101 plet generation is conserved not only during infection with genetically diverse Toxoplasma strains bu

102 CD163 knockout (KO) pigs are resistant to infection with genotype 2 (type 2) porcine reproductive

103 n is well-recognized as a common blood-borne infection with global public health impact affecting 3 t

104 utrition for the embryo and protects against infection, with glycosylation responsible for binding ce

105 elevation with fevers, and grade 3 pulmonary infection with grade 3 maculopapular rash.

106 o meet the urgent clinical needs in treating infections with Gram-negative bacteria.

107 tractive drug repurposing candidate to treat infections with Gram-negative bacteria.

108 que gene pathways upregulated in response to infection with GRG.

109 ents included hospitalizations for a serious infection with >/=2 systemic inflammatory response syndr

110 has been effectively preventing chronic HBV infection with >90% efficacy in countries with universal

111 Our previous study demonstrated that infection with H. pylori HpslyD-positive strains associa

112 work was to investigate whether experimental infection with H. pylori, or prophylactic treatment with

113 -infected patients receiving ART, chronic co-infection with HBV and HCV is associated with an increas

114 Infection with HCV can lead to the reorganization of mem

115 a laboratory result at screening indicating infection with HCV genotype 1b subtype only.

116 and primary human hepatocytes, we found that infection with HCV leads to activation of nuclear factor

117 ients with chronic atrophic gastritis due to infection with Helicobacter pylori; it might be a precur

118 ted the effects of strictly enteric helminth infection with Heligmosomoides polygyrus on respiratory

119 misation by screening HIV-1 RNA value and co-infection with hepatitis B or C.

120 Occult infection with hepatitis C virus (HCV) is defined as the

121 Chronic infection with hepatitis C virus (HCV) is one of the mai

122 hronic antigen stimulation during persistent infection with hepatitis C virus is associated with cont

123 Chronic infections with hepatitis C virus (HCV) and HIV are high

124 Ocular infection with herpes simplex virus 1 (HSV-1) sets off a

125 ogene 141 (RNA5SP141), bound to RIG-I during infection with herpes simplex virus 1 (HSV-1).

126 Infections with high-risk human papillomaviruses (HPVs)

127 ssociated with later initiation of ART after infection, with higher DNA and cell-associated RNA level

128 Risk factors for human infection with highly pathogenic (HP) and low-pathogenic

129 Human infections with highly pathogenic avian influenza A (H5N

130 Infection with HIV type 1 is a major risk factor for TB,

131 During infection with HIV type 1, human pDCs decrease in circul

132 a model of low multiplicity of S. pneumoniae infection with HL-1 mouse cardiomyocytes to investigate

133 Ocular infection with HSV causes a chronic T cell-mediated infl

134 imal work, implying that in vivo cellular co-infection with HSV-1 and HSV-2 yields viable interspecie

135 Infection with HSV-1 induced relocalization of RNA5SP141

136 ulating factor 1 (CSF-1) DNA prior to ocular infection with HSV-1.

137 ect the ability of their carriers to control infections with human hepatitis B (HBV) and C (HCV) viru

138 I is a determinant of host susceptibility to infection with IAV.

139 Moreover, 78% of the pigs had recurrent infections with IAVs closely related to each other or IA

140 id not induce an antiviral response, whereas infection with influenza A virus, herpes simplex virus 1

141 nfluenza-related childhood deaths are due to infection with influenza B viruses, which co-circulate i

142 Infection with influenza virus induces antibodies to the

143 A viruses, but were almost as susceptible to infection with influenza viruses of human origin as nont

144 Infections with influenza A(H1N1) was suggested to be mo

145 es aegypti mosquitoes, and strongly inhibits infection with key human pathogens including the dengue

146 , IL-17A-deficient mice cleared Pneumocystis infection with kinetics similar to C57BL/6 mice.

147 infected with R. typhi(GFPuv) succumb to the infection with kinetics similar to those for animals inf

148 cells are able to support a productive HSV-1 infection, with kinetics and overall titers similar to t

149 uli in vitro and in vivo during pneumoseptic infection with Klebsiella pneumoniae, indicating its reg

150 m an IgG1 response to an IgG3 response after infection with L. interrogans Histological periodic acid

151 ed strains of Pg were compared with the same infection with lactose as coaggregation inhibitor.

152 of ROS in C57BL/6 mice following intradermal infection with Leishmania amazonensis.

153 d canine visceral leishmaniasis is caused by infection with Leishmania infantum, a Protist parasite t

154 ivo, we developed a novel approach utilizing infection with Listeria monocytogenes (LM) encoding prot

155 Indeed, following infection with Listeria monocytogenes, DNA-PKcs-deficien

156 ived mouse macrophages and cell line J774 to infection with live and gamma-irradiated (killed) M. tub

157 and were investigated for associations among infection with liver fluke, Helicobacter and hepatobilia

158 Importantly, infection with LM-PLP ameliorated established disease.

159 adolescents is often due to accumulation of infections with long-lived schistosomes from early life.

160 Infection with low-dose A/X31 H3N2 led to prolonged dete

161 constitute a linchpin in multiple aspects of infections with Lyme disease borrelia, providing a link

162 During chronic infection with lymphocytic choriomeningitis virus (LCMV)

163 B cell and CD4 T cell responses during acute infection with lymphocytic choriomeningitis virus.

164 occur after acute viral infections, such as infections with lymphocytic choriomeningitis virus (LCMV

165 hage sensing of Mycobacterium smegmatis Upon infection with M. smegmatis, macrophages from knock-in m

166 e to nosocomially acquired, catheter-related infections with M. bovis-BCG in patients with indwelling

167 tracellular microbes, but could also promote infection with macrophage-tropic pathogens.

168 bNAbs to HIV develop during infection, with many showing dependence on glycans for b

169 ian rousette develops subclinical productive infection with MARV but is refractory to EBOV.

170 highly contagious disease that results from infection with measles virus and is still responsible fo

171 T cell differentiation, we have analyzed an infection with mouse cytomegalovirus, a persistent-laten

172 ng in ZBP1's ZBDs prevented necroptosis upon infection with mouse cytomegalovirus.

173 Infection with MRCPEC is associated with sex, immunosupp

174 erse responses of critically ill patients to infection with multi-drug resistant (MDR) bacteria are d

175 mallei ATCC 23344, it also protects against infection with multiple isolates of the closely related

176 can cause rapidly fatal, widely disseminated infection with multisystem organ failure in patients wit

177 Analysis of spacer acquisition after infection with mutant phages demonstrated that most spac

178 Infection with Mycobacterium tuberculosis (Mtb), the bac

179 well-established guinea pig model of aerosol infection with Mycobacterium tuberculosis, BCG and MTBVA

180 tightly regulated to respond efficiently to infection with neurotropic pathogens.

181 e a hallmark of central nervous system (CNS) infections with neurotropic pathogens, post-infectious n

182 sed by dysregulated inflammatory response to infection with no effective therapy available.

183 veolar bone loss compared with that of mixed infection with non-capsulated Pg.

184 species, Plasmodium lomamiensis sp. Rare co-infections with non-Laverania parasites were also observ

185 with increased incidence of tuberculosis and infections with non-tuberculous mycobacteria in human po

186 he chemotherapy plus bevacizumab group), and infections with normal neutrophil count (42 events vs 53

187 se efficacy in patients with HCV genotype 1a infection with NS5A polymorphisms.

188 Among patients with HCV genotype 4a or 4d infections with NS5A polymorphisms, all 26 who received

189 The significant relationships of HCV infection with nuclear and any cataract were formed only

190 Here we report that infection with NW arenaviruses JUNV and MACV, but not OW

191 recipients with chronic genotype 1 or 4 HCV infection, with or without compensated cirrhosis, and wi

192 In conclusion, patients with HBV or HCV infection, with or without HCC, have distinctly differen

193 2-cross of mice resistant and susceptible to infection with oral bacterial pathogens.

194 ex and CMV were in part explained by age and infection with other herpesviruses.

195 Unlike infections with other parvoviruses, HBoV1 infection did

196 lthough QS is characterized in T. brucei, co-infections with other trypanosome species (Trypanosoma c

197 th pioglitazone, a PPARgamma agonist, before infection with PAO1 and 3O-C12-HSL.

198 is a debilitating tropical disease caused by infection with parasitic blood flukes.

199 glected tropical disease caused by a chronic infection with parasitic helminths of the genus Schistos

200 ise 5% of the population, harbor a third of infections with patent gametocytes between May and Augus

201 Here the authors show that in Drosophila, infection with pathogenic bacteria leads to increased ph

202 cal need for new antifungal agents to manage infections with pathogenic species such as Cryptococcus

203 Congenital infections with pathogens such as Zika virus, Toxoplasma

204 days (Participant B; 31-year-old male) after infection with peak plasma HIV RNA of 220 copies/mL and

205 nts, clinical disease did not differ between infection with pertactin-deficient and those with pertac

206 d development, and did not protect mice from infection with PfCSP transgenic Plasmodium berghei sporo

207 imilarly to pH1N1/NSs-wt in mouse lungs, but infection with pH1N1/NSs-6mut induced lower levels of pr

208 Malaria infections with placental sequestration have long-lastin

209 ng immunization with T-dependent antigens or infection with plasmodium C. chabaudi.

210 also upregulated at peak parasitemia during infection with Plasmodium chabaudi Concentrations of the

211 -like T cell and NK cell responses following infection with Plasmodium has been challenging because t

212 nocompetent C57BL/6 mice over time following infection with Pneumocystismurina We also examined the c

213 irs anti-viral immunity during an early-life infection with pneumonia virus of mice (PVM; a murine an

214 ages (BMMs) in which activity was induced by infection with Porphyromonas gingivalis The expression o

215 1.5g and 1g in the proportions of wild-type infections with post-treatment resistance mutations: 4/3

216 Patients with hepatitis C virus genotype 3 infection with prior treatment experience and/or compens

217 structure class active against M. abscessus infections with promising translational development poss

218 Re-infection with PVM in later-life induced many of the car

219 ces between the pathogenic and nonpathogenic infections with regard to dynamics of the memory B cell

220 ast, our study in humans supports a role for infection with reovirus, a seemingly innocuous virus, in

221 41 of 93 (44%) treated subjects experienced infection with resistant virus while in the isolation fa

222 In contrast, infection with RESTV failed to stimulate a strong host r

223 for adaptive immune responses against acute infections with retroviruses.

224 disease tissue model was used for artificial infection with S aureus.

225 on of neutrophils under conditions mimicking infection with S. aureus conferred responsiveness to IL-

226 inflammatory functions of neutrophils during infection with S. aureus.

227 Chronic infection with S. haematobium has been linked with bladd

228 d maintained for 10 days before intravitreal infection with S. pneumoniae E353.

229 ontributed to the protection of mice against infection with S. pneumoniae in which iNKT cells have pr

230 Since immunocompetent mice are resistant to infection with S. stercoralis, we hypothesized that NSG

231 creased in the jejunal mucosa during primary infections with S. venezuelensis Studies in basophil-def

232 After infection with SARS-CoV, the acute lung injury caused by

233 n60 UT sequences, while identifying a double infection with SbGP/MPV and aster yellows (16SrI) phytop

234 Here, we show that DC infection with seasonal IAV causes immunogenic RIPK3-med

235 y identified 1.9-85.9% of confirmed Shigella infections, with sensitivity decreasing over time (p=0.0

236 f human infections.IMPORTANCE Rhesus macaque infection with simian immunodeficiency virus (SIV) has s

237 In contrast, during nonpathogenic infection with SIV from African green monkeys (SIVagm),

238 Accordingly, infections with SIVmac239, but not with Delta5G, deplete

239 outcomes, supporting differential effects of infection with specific parasite strains.

240 nt protected mice against lethal soft tissue infection with Streptococcus pyogenes and prevented bact

241 sensitive and specific imaging of bacterial infection with strong translational potential.

242 Infections with Strongyloides stercoralis are of conside

243 inants of whether species experience greater infection with supplemental feeding.

244 immunological intervention to combat chronic infection with T. gondii by targeting the persistent cys

245 e, we define the origin of AAMvarphis during infection with Taenia crassiceps, and their disease-modu

246 To investigate whether infection with TC-PC177 can induce cross-protection agai

247 asma cells to mediate protection at sites of infection with that of bone marrow plasmablasts and plas

248 hospital-acquired pneumonia and is caused by infection with the bacterium Legionella.

249 Infection with the cyst stage induces proinflammatory im

250 Melioidosis, a severe infection with the environmental bacterium Burkholderia

251 their importance, the role of ROS following infection with the eukaryotic pathogen Leishmania has no

252 al delivery of GFP11-tagged effectors during infection with the foliar pathogen Pseudomonas syringae

253 induction of disease-responsive genes after infection with the fungus Ophiostoma novo-ulmi.

254 on, leading to delayed worm expulsion during infection with the gastrointestinal helminth Nippostrong

255 patients, we examined the association of HCV infection with the incidence of CKD.

256 characterize the response of macrophages to infection with the intracellular bacterial pathogen Legi

257 expression of activation/memory genes during infection with the intracellular parasite Trypanosoma cr

258 ny-forming units/mL; P < .01) as compared to infection with the lukS/F-PV (Deltapvl) mutant.

259 ic; review risk factors for colonization and infection with the most common transmissible CPE worldwi

260 ) bacteria are a novel, potent tool to study infection with the pathogen in vitro and in vivo and the

261 associated with diabetes prevalence and HBV infection with the risk of incident diabetes.

262 in S. solfataricus is induced in response to infection with the S ulfolobus turreted icosahedral viru

263 arbouring a type II CRISPR-Cas9 system after infection with the staphylococcal bacteriophage varphi12

264 An infection with the Zika virus (ZIKV) is usually mild, wi

265 ome susceptible to the lethal effects of HSV infection, with the virus spreading to the brain causing

266 Infections with the human hepatitis B virus (HBV) and he

267 promised patients are susceptible to develop infections with the opportunistic pathogenic fungus Aspe

268 aptive immune responses to influenza A virus infection, with their effect on the outcome of infection

269 terventions designed to reduce the burden of infection with these pathogens are needed.

270 omplications related to monoinfection and co-infection with these two closely related viruses.

271 h concern due to the repeated high levels of infection with these viruses and their perceived pandemi

272 The mortality rate after infection with these viruses is high, but the mechanism

273 Despite a high prevalence of infection with these viruses, only a minority of infecte

274 es in patients with sepsis who acquire a new infection with those who do not.

275 Diet strongly modified host survival after infection, with those on the high fat/low protein diet s

276 have decreased quality of life and recurrent infections with treatments limited to palliative measure

277 Previously, we demonstrated that infection with Turnip mosaic virus, a member of one of t

278 distinct host responses are elicited by the infections with two different viruses.

279 rs for development of health-care-associated infections with use of a generalised linear mixed-effect

280 Oral HPV infection with vaccine types 16, 18, 6, or 11 was compar

281 ly studies revealed IgM and IgG responses to infection with various filoviruses, but recent outbreaks

282 onises miR-122, in patients with chronic HCV infection with various genotypes.

283 ough C57BL/6 mice normally resistant to TMEV infection with viral clearance, we have previously demon

284 ssion in T cells, became susceptible to TMEV infection with viral persistence.

285 or 1% of the total DEGs at any time point of infection with virulent or defense-inducing DC3000 strai

286 Infections with virulent pathogens, in contrast, may act

287 a robust decrease in viral replication upon infection with Vpr-deficient HIV-1.

288 ood cells: (i) 14 subjects with a history of infection with West Nile virus (WNV), (ii) 34 healthy su

289 Comparative infection with wild-type and epithelial cell receptor-bl

290 icits protective immunity against subsequent infection with wild-type bacteria.

291 ome different from that generally induced by infection with wild-type parasites.

292 Infection with wild-type PtoDC3000 causes proteasome act

293 Infection with wild-type S. aureus suppressed inflammato

294 ollowing transfection of cells with UnaG and infection with wild-type virus, passage of UnaG through

295 Infection with Wuchereria bancrofti was diagnosed with a

296 Infection with Zika virus (ZIKV) during pregnancy may ca

297 the expanded cerebral organoids to show that infection with Zika virus impairs cortical growth and fo

298 the rhesus macaque model we show that prior infection with Zika virus leads to a significant enhance

299 ytoplasmic incompatibility, or resistance to infection with Zika virus.

300 4(+)CD16(+) monocytes are the main target of infection, with ZIKV replication detected in some dendri