ライフサイエンスコーパス: infectious

1 eriod when endogenous retroviruses are still infectious.

2 uggest that newly formed prion oligomers are infectious.

3 of the SNARE system, significantly affected infectious AcMNPV production.

4 Staphylococcus aureus is the most common infectious agent causing pyogenic spondylodiscitis.

5 oop contributes to pathological responses to infectious agents and is therefore tightly regulated.

6 Tests for infectious agents and pesticides were negative.

7 Most FDA-approved adjuvants for infectious agents boost humoral but not cellular immunit

8 eterioration remains elusive and no specific infectious agents could be discerned.

9 id diagnostics that enable identification of infectious agents improve patient outcomes, antimicrobia

10 blood profiling using RNASeq to discriminate infectious agents in adults with microbiologically defin

11 Their emergence as infectious agents in humans coincided with changes in th

12 eroviruses (EVs) are among the most frequent infectious agents in humans worldwide and represent the

13 onsidered, it is important to test for other infectious agents in parallel, as cross-reactivity can o

14 can result in productive replication of the infectious agents in the recipient cell.

15 Immunity to infectious agents involves a coordinated response of inn

16 Prions are infectious agents that cause neurodegenerative diseases

17 Prions or PrP(Sc) are proteinaceous infectious agents that consist of misfolded, self-replic

18 of animal models to experimentally study how infectious agents transmit between hosts limits our unde

19 detection in the BALF by PCR, whereas other infectious agents were undetectable.

20 ic cell receptor DC-SIGN by numerous chronic infectious agents, including Porphyromonas gingivalis, i

21 in the cultivation and management of highly infectious agents, such as acid-fast bacilli and systemi

22 ich in the case of some pathogens act as the infectious agents.

23 tted through fomites: objects able to convey infectious agents.

24 lities in complement functions occur in many infectious and autoimmune disorders that have been linke

25 nderstand the cell-source for new neurons in infectious and inflammatory colitis.

26 e in host immunity and tissue homeostasis in infectious and inflammatory diseases.

27 ng bacteria entails uncontrollable risks for infectious and metabolic or malignant diseases, particul

28 aboratory investigations to assess potential infectious and non-infectious causes of this acute neuro

29 mune system's response to different forms of infectious and noninfectious pathologies.

30 The factors that distinguish infectious and pathogenic protein aggregates from more i

31 s a central event in the context of numerous infectious and sterile inflammatory conditions.

32 uenza transmission with the distance between infectious and susceptible cities, consistent with sprea

33 ns is determined by contact patterns between infectious and susceptible individuals in the population

34 nflammatory, hypoxic, ischemic/hypertensive, infectious and thrombotic etiologies were diagnosed, bli

35 Developing research in infectious and tropical diseases in Africa is urgently n

36 Three quarters of cases with infectious and two thirds of cases with noninfectious en

37 ent evidence suggests that these viruses are infectious, and the potential exists for HK2 to contribu

38 ized prior to chicken domestication, remains infectious, and threatens poultry industry.

39 can be efficiently used to study virus-host infectious associations.

40 gical agent of tularemia, is one of the most infectious bacteria known.

41 h either bovine respiratory syncytial virus, infectious bovine rhinotracheitis, bovine viral diarrhea

42 In this study, infectious bursal disease virus (IBDV) was used to inves

43 feron-alpha (chIFN-alpha) and the attenuated infectious bursal disease virus vaccine strain PBG98.

44 Leprosy, the leading infectious cause of disability worldwide, remains a majo

45 an cytomegalovirus (HCMV) is the most common infectious cause of fetal anomalies during pregnancy, de

46 is the most frequent, yet under-recognised, infectious cause of newborn malformation in developed co

47 ained uveitis specialists after exclusion of infectious causes and neoplastic masquerades of uveitis.

48 However, Zika virus is only one of the infectious causes of microcephaly and, although the cont

49 tions to assess potential infectious and non-infectious causes of this acute neurological illness.

50 r (KGF) markedly accelerated mortality after infectious challenge with influenza A virus (IAV).

51 ro-inflammatory cytokines in response to the infectious challenge.

52 n considered capable of retaining memory for infectious challenges.

53 the start codon of two C-terminal ORFs in an infectious clone reduced virus yield.

54 We generated a two-plasmid infectious clone system from which infectious virus was

55 The recombinant ZIKV generated from the infectious clone, which contains the VNDT motif, is high

56 Infectious clone-derived virus initiated infection and t

57 s and silencing, and was immune to wild-type infectious clones corresponding to CaLCuV or Beet curly

58 enders mice susceptible to a more aggressive infectious colitis caused by Citrobacter rodentium.

59 the leading cause of mortality cancer (25%), infectious complications (25%), and cardiovascular disea

60 0.8 +/- 1.1; p < 0.0001) and developed more infectious complications (84% vs 35%; p < 0.0001).

61 n is common and can largely be attributed to infectious complications and inability to maintain adequ

62 ative blood transfusions are associated with infectious complications and increased risk of cancer re

63 ated with a significant decrease in post-ERC infectious complications compared to non-use (14.3% vs.

64 to ERC contrast media in preventing post-ERC infectious complications in a high-risk study population

65 s the first study that evaluates ERC-related infectious complications in patients with secondary scle

66 Outcomes comprised infectious complications within 3 days after ERC.

67 of their high rates of late respiratory and infectious complications.

68 ion factor eRF3 (Sup35), can be cured of its infectious conformation by overexpression of Hsp104, whi

69 arged cases with data available expectorated infectious culture-positive cough aerosols in the respir

70 TNF inhibited completion of the HCV infectious cycle in hepatoma cells and HFLCs in a dose-d

71 ficance that require IMPalpha/beta1 in their infectious cycle.

72 anscription to genome replication during the infectious cycle.

73 ments encountered throughout its tick-mammal infectious cycle.

74 reparations they evolved to perpetuate their infectious cycle.

75 t only to bacterial signals, but also to non-infectious danger-associated molecular patterns that act

76 on prevention and control aspects related to infectious diarrhea.

77 antibiotics no longer recommended for acute infectious diarrhoea.

78 An infectious disease (ID) consultation is often obtained t

79 The impact on patient survival of an infectious disease (ID) team dedicated to the early mana

80 We find that, for a mild infectious disease (low infection probability) on a temp

81 d from the National Institute of Allergy and Infectious Disease (NIAID) workshop 'Complex Systems Sci

82 n the Seattle Structural Genomics Center for Infectious Disease (SSGCID) structure determination pipe

83 to improve the efficacy of vaccines against infectious disease and immunotherapies for cancer, autoi

84 equire ongoing commitments to eradication of infectious disease and increase the emphasis on chronic

85 forward through the morass of drug-resistant infectious disease and should be fully explored.

86 formed adaptations that reduce the impact of infectious disease and that are expected to maximize the

87 ons in tropical countries is needed, and the infectious disease burden in these countries is another

88 Poliomyelitis is a highly infectious disease caused by PV and is on the verge of e

89 We conclude that infectious disease could lead to increased uncertainty i

90 and valuable resource for understanding the infectious disease dynamics in wildlife.

91 facilitate the testing of countermeasures in infectious disease emergencies.

92 ich will affect the ecology and evolution of infectious disease epidemics.

93 rPH (1922-2007), was initially trained as an infectious disease epidemiologist at the Johns Hopkins S

94 impact of pathogen evolutionary dynamics on infectious disease epidemiology.

95 istribution of antibody titers to an endemic infectious disease may include information on multiple s

96 SD increment: 1.47; 95% CI: 1.12, 1.95), and infectious disease mortality (HR per SD increment: 1.50;

97 kinsea might represent the third most common infectious disease of anurans after ranavirus infections

98 Our findings suggest that a severe infectious disease of tadpoles caused by a protist belon

99 lth needs and better protect the public from infectious disease often motivates the transition.

100 samples becomes more and more routine during infectious disease outbreaks.

101 factors can have a substantial influence on infectious disease patterns, altering density of pneumoc

102 acterium tuberculosis remains a major global infectious disease problem, and a more efficacious vacci

103 p programs support, and do not compete with, infectious disease programs.

104 profiles in anthropogenic habitats to reduce infectious disease risks in provisioned populations.

105 o burn patients with a team that includes an infectious disease specialist and a pharmacist in additi

106 for evaluating molecular devices for use in infectious disease testing.

107 Dengue is an important infectious disease that presents high incidence and yiel

108 odontitis, which is the sixth most prevalent infectious disease worldwide (2) , ensues from the actio

109 bal health problem and the 6(th) most common infectious disease worldwide.

110 nds critically on the natural history of the infectious disease, its inherent transmissibility, and t

111 ed how environmental degradation exacerbates infectious disease, the effects of human health on our u

112 t multiple National Institute of Allergy and Infectious Disease-assigned category A priority pathogen

113 he development of new therapeutic agents for infectious disease.

114 tion in ChrY in regulating susceptibility to infectious disease.

115 endangered wildlife against a rising tide of infectious disease?

116 ggests potential implications for immune and infectious-disease-related outcomes.

117 est rising primary noncardiac diagnoses were infectious diseases (7.8%-15.1%) and respiratory disease

118 The approach used so far for emerging infectious diseases (EIDs) does not work from the techni

119 Emerging infectious diseases (EIDs) threaten the health of people

120 Infectious diseases (ID) consultation and antimicrobial

121 vergent risk pattern in the risk of 4 common infectious diseases after bariatric surgery.

122 onship of bariatric surgery with the risk of infectious diseases among obese adults.

123 sed therapies and foster new applications in infectious diseases and autoimmunity.

124 based compounds have been exploited to treat infectious diseases and cancer, with such chemicals ofte

125 o the development of mitigation policies for infectious diseases and financial contagion in economic

126 molecular mechanisms of disease, focusing on infectious diseases and host-pathogen interactions, canc

127 the most pressing challenges in the field of infectious diseases and is one of 4 key areas of unmet m

128 Infectious diseases are one of the most common threats f

129 r POC development is the ability to diagnose infectious diseases at sites with a limited infrastructu

130 Effective reduction of the spread of infectious diseases can be achieved through collaboratio

131 losis (TB) remains one of the most prevalent infectious diseases causing morbidity and death in >1.5

132 In contrast, infectious diseases diagnostics must contend with scores

133 After implementing infectious diseases e-consults within an electronically

134 Historically, diagnosis of infectious diseases has relied on pathogen detection; ho

135 tterns relevant to the spread of respiratory infectious diseases in Hong Kong.

136 Infectious diseases in livestock can be transmitted thro

137 ing a research hospital for the treatment of infectious diseases in Marseille.

138 m perfringens is one of the most detrimental infectious diseases in poultry.

139 Tuberculosis remains one of the deadliest infectious diseases in the world, and the increased numb

140 y for the simultaneous prevention of several infectious diseases in vulnerable populations.

141 ts to offer BLAST for eligible patients with infectious diseases receiving nonpreferred therapy due t

142 r, a novel concept to improve diagnostics in infectious diseases relies instead on the detection of c

143 Infectious diseases represent one of the greatest potent

144 In 2016, the Infectious Diseases Society of America (IDSA) recommende

145 ters for Disease Control and Prevention, and Infectious Diseases Society of America searched, selecte

146 The Infectious Diseases Society of American considers adhere

147 eeded to address established arthropod-borne infectious diseases such as dengue and yellow fever and

148 National Institute of Allergy and Infectious Diseases supported this analysis.

149 If the control of infectious diseases was the public health success story

150 esitancy, which risks the resurgence of many infectious diseases with public health and economic cons

151 contributes to both chronic inflammatory and infectious diseases, and may have protective or pathogen

152 ding strokes, trauma, inflammatory diseases, infectious diseases, and neurodegenerative diseases.

153 with great potential for nuclear imaging of infectious diseases, as its cationic-rich fragment TGRAK

154 f alleles conferring survival advantages for infectious diseases, but that are maladaptive in modern-

155 stranded DNA (dsDNA) viruses associated with infectious diseases, but they are better known as tools

156 In the context of infectious diseases, however, less is known about the in

157 For many infectious diseases, however, there is pronounced season

158 from increased morbidity and mortality from infectious diseases, independent of immunosuppressive th

159 eading to anemia, including malnutrition and infectious diseases, may also play a role in the develop

160 emonstrate that obesity is a risk factor for infectious diseases, no study has investigated the relat

161 l-being via its effects on climate-sensitive infectious diseases, potentially changing their spatial

162 tic and diagnostic biomarkers in many common infectious diseases, such as Tuberculosis (TB).

163 Numerous studies have reported sex bias in infectious diseases, with bias direction dependent on pa

164 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations an

165 in a 2016 National Institutes of Allergy and Infectious Diseases-funded Technical Consultation focuse

166 antibiotic use was adjudicated by at least 2 infectious diseases-trained clinicians and according to

167 ith time, lead to increased vulnerability to infectious diseases.

168 sporter may serve as therapeutic targets for infectious diseases.

169 n affect the transmission and persistence of infectious diseases.

170 es remain the most effective tool to prevent infectious diseases.

171 between individuals to prevent the spread of infectious diseases.

172 such goal will affect the ability to control infectious diseases.

173 rgets for treating cancer, autoimmunity, and infectious diseases.

174 entially allowing prevention or treatment of infectious diseases.

175 ut also offers adaptability to model similar infectious diseases.

176 ntal demands increase the risk of particular infectious diseases.

177 therefore increase susceptibility to diverse infectious diseases.

178 eed for improved diagnostics in the field of infectious diseases.

179 aid in the control of zoonotic and emerging infectious diseases.

180 if we are to continue to successfully treat infectious diseases.

181 eases from cancer and autoimmune diseases to infectious diseases.

182 this supplemental edition of the Journal of Infectious Diseases.

183 es, as well as in the progression of certain infectious diseases.

184 s increasingly affecting the epidemiology of infectious diseases.

185 receptor (S1PR) agonism in the treatment of infectious diseases.

186 xtrapulmonary tuberculosis, or any bacterial infectious disorder of grade 4 severity, that required u

187 his procedure on diagnostic test results and infectious Ebola virus (EBOV) titers.

188 6 knockout cells have reduced replication of infectious EBOV, suggesting that VP35 hijacks TRIM6 to p

189 er pulmonary valve stent fracture (3.4%) and infectious endocarditis (4.3%) were both low.

190 Infectious endophthalmitis developed in 18 of 88 150 inj

191 IBS was 4.2-fold higher in patients who had infectious enteritis in the past 12 months than in those

192 S was 2.3-fold higher in individuals who had infectious enteritis more than 12 months ago than in ind

193 risk factors for, and outcomes of IBS after infectious enteritis.

194 of PD-1 and Tim-3 expression by T cells and infectious episodes in transplant patients.

195 contrast media efficiently reduced post-ERC infectious events in patients with biliary obstruction.

196 ersion enzyme, resulted in the generation of infectious extracellular virions (HSV(des)) that lack ch

197 technique for early detection of metastatic infectious foci, often leading to treatment modification

198 old immunocompetent CD-1 mice with 1 x 10(4) infectious focus units (IFU) of 10-del ZIKV caused no mo

199 ntify and effectively treat individuals with infectious forms of tuberculosis.

200 HCV replicon system but not in an authentic infectious HCV cell culture (HCVcc) system.

201 Infectious HCV epitope mutants encoding the well-defined

202 We used the fish rhabdovirus infectious hematopoietic necrosis virus (IHNV) as a mode

203 LJ001 was preincubated with our model virus, infectious hematopoietic necrosis virus (IHNV), infectiv

204 " mouse model that better mimics the diverse infectious history that is typical of most humans.

205 p analysis on HD patients who experienced an infectious hospitalization event within 60 days (HD+) (n

206 ermissive for HRV replication and release of infectious HRV particles.

207 ese findings have important implications for infectious HTLV-1 spread, particularly in the context of

208 cation and produces progeny virions that are infectious in HAE.

209 system and isolated HEV particles that were infectious in vitro and in vivo.

210 of secondary infections produced by a random infectious individual.

211 re effective than risk-aversion because when infectious individuals change behavior, they reduce all

212 portance of chance events when the number of infectious individuals is small.

213 t of new therapeutic strategies that resolve infectious inflammation without unwanted side effects.

214 INTERPRETATION: Despite a high infectious inflammatory burden, the Tsimane, a forager-h

215 th few cardiovascular risk factors, but high infectious inflammatory burden.

216 ined a complex genetic architecture in major infectious, inflammatory, and autoimmune disorders.

217 Brucella species are infectious intracellular pathogens that replicate in pro

218 idence on the role of gut microbiota in post-infectious irritable bowel syndrome (PI-IBS) is convinci

219 sduce the neurotoxic effects of PrP(Sc), the infectious isoform, but how this occurs is mysterious.

220 If people with asymptomatic infection are infectious it could explain re-emergences of Ebola virus

221 Infectious keratitis is a major global cause of visual i

222 Identifying patients with infectious keratitis who are at risk of experiencing a p

223 t to a different location, were treated with infectious, misfolded forms of the prion protein, PrP(re

224 clear cells from Chinese children with acute infectious mononucleosis (AIM) and chronic active EBV in

225 Epstein-Barr virus is the causative agent of infectious mononucleosis and infects approximately 90% o

226 s (EBV) poses numerous health risks, such as infectious mononucleosis and lymphoproliferative disorde

227 infections with neurotropic pathogens, post-infectious neurologic dysfunction has traditionally been

228 s in serum samples from patients with varied infectious or autoimmune disorders, and in the case of S

229 ne functions and, ultimately, the outcome of infectious or malignant disease.

230 s) or secondary (resulting from a malignant, infectious, or autoimmune stimulus without an identifiab

231 gate the potentially catastrophic effects of infectious outbreaks in farmed animals.

232 ction and culling of an infected herd on the infectious output.

233 an also be applied in the diagnosis of other infectious-parasitic diseases.

234 also identified the precise sequence of the infectious particle-associated ORF2 capsid protein.

235 a source case of tuberculosis (2) generates infectious particles (3) that survive in the air and (4)

236 ntly of the host cell genome and produces no infectious particles, is required for long-term virus pe

237 specifically inhibit HCV by interacting with infectious particles.

238 uced phage replication and the generation of infectious particles.

239 sential for adaptive T-cell immunity against infectious pathogens and cancers.

240 Infectious pathogens contribute to the development of au

241 A fundamental mystery for dengue and other infectious pathogens is how observed patterns of cases r

242 l antibody immunotherapeutics for additional infectious pathogens.DNA-delivered monoclonal antibodies

243 has been shown to be involved in several non-infectious physiological processes.

244 Infectious plant diseases are caused by pathogenic micro

245 particles called prions are associated with infectious prion diseases in mammals and inherited pheno

246 h infected animals and indirect contact with infectious prions in bodily fluids and contaminated envi

247 n lipid rafts and lipid cofactors generating infectious prions in in vitro models.

248 Diagnosis of an infectious process was based on microbiologic or patholo

249 ay in HIV-1-producing cells resulted in less infectious progeny virions.

250 ruses to suppress host defenses and generate infectious progeny.

251 cellent biomarker for detecting asymptomatic infectious reservoirs otherwise missed by the most sensi

252 (ii) use of Public Health System (PHS) high infectious risk donors, (iii) wait time, and (iv) living

253 Finally, to determine the rate of infectious-RNA incorporation into new virions, we develo

254 esis mechanisms of viroids and perhaps other infectious RNAs.IMPORTANCE Numerous pathogens, including

255 tic fadeouts after multiple introductions of infectious rodents migrating from neighbouring areas.

256 ome, 38.5% of the genes upregulated upon pre-infectious root colonization encoded extracellular prote

257 One such orthomyxovirus, infectious salmon anemia virus (ISAV), spreads easily th

258 At the infectious site, the AMPs can be activated by bacterial

259 ode development, including the all-important infectious stage.

260 s of shrews, which would reflect the dynamic infectious status and circulation of MJNV in nature.

261 c killers to myeloid-like APC in response to infectious stimuli.

262 The safe handling of category A infectious substances is a unique challenge in this envi

263 s degraded by cellular proteases to generate infectious subviral particles (ISVPs).

264 ungal immunity, respectively, explaining the infectious susceptibility of DOCK8-deficient patients.

265 e same temporal pattern of proliferation and infectious susceptibility.

266 uses from the tenofovir arm were 2-fold less infectious, they replicated at rates similar to those of

267 Emerging pandemic infectious threats, inappropriate antibacterial use cont

268 ere infected with EcoHIV (modified HIV virus infectious to mice) and HIV, respectively, in the presen

269 modium falciparum parasites through to human-infectious transmission stages is influenced by the host

270 d rCD4 cells in this Ugandan cohort was 0.36 infectious units per million cells (IUPM; 95% confidence

271 3-5R strongly reduces the number of excreted infectious viral particles.

272 Gag interactions are the nucleation event of infectious virion assembly, ensuring that one RNA dimer

273 Infectious virion production is activated by the essenti

274 -1 assembly leading to induced production of infectious virions by targeted modulation of Gag PM targ

275 ed that B1 is critical for the production of infectious virions in various cell types and is sufficie

276 ids, a critical process in the production of infectious virions subsequent to DNA replication.

277 gen gene replication but avoid production of infectious virions, we developed "single-cycle" adenovir

278 4 results in severely impaired production of infectious virions, with a decrease as great as 5 logs.

279 esulting in the severe loss of production of infectious virions.

280 is required for the efficient production of infectious virions.

281 e colonies, quickly become infected, produce infectious virus and undergo lysis within 48 h after exp

282 tive, large-scale screening and titration of infectious virus in experimental and clinical samples, i

283 urons, viral gene expression is minimal, and infectious virus is not released.

284 viral and host factors to optimally produce infectious virus particles.

285 reactivation and the corresponding amount of infectious virus produced in the ganglia per reactivatio

286 ion at residue 76 (Y76A), were essential for infectious virus production and filament formation while

287 ll plaque formation and drastic reduction in infectious virus production, while mutation of C82 and C

288 Attempts to isolate infectious virus rely on in vivo or basic cell culture a

289 Infectious virus titers were present in the blood and mo

290 o-plasmid infectious clone system from which infectious virus was rescued that replicates in human an

291 S5A- or protease-inhibitors can generate non-infectious virus, we incorporated this effect into a mat

292 s temporal replication without production of infectious virus.

293 gut, and contained replication-competent and infectious virus.

294 kes and nucleocapsid is necessary to produce infectious virus.

295 ion, including reactivation to produce newly infectious virus.

296 nine bacterial host genera with at least 45 infectious viruses, we show that random forest together

297 he AAA ATPase p97/VCP in a similar manner to infectious viruses.

298 ncluding a minimum of 30 mL/kg of IV fluids, infectious workup including blood cultures, broad-spectr

299 The infectious workup was negative for all three patients, a

300 ittle to herd immunity in Ebola, and even if infectious, would account for few transmissions.