ライフサイエンスコーパス: infectious agent

1 tailored and robust manner, inclusive of the infectious agent.

2 e misfolded proteins ("prions") are also the infectious agent.

3 Torque Teno virus (TTV) is a ubiquitous infectious agent.

4 ells expressing antibodies that can bind the infectious agent.

5 ins from blood without first identifying the infectious agent.

6 cause of mortality worldwide due to a single infectious agent.

7 nced the transmission characteristics of the infectious agent.

8 e similar, but not identical to the original infectious agent.

9 behavior differed markedly from that of the infectious agent.

10 s via multiple mechanisms depending upon the infectious agent.

11 of human mortality attributable to a single infectious agent.

12 lopathies is central to the debate about the infectious agent.

13 ing the disease process and/or targeting the infectious agent.

14 lta(-)/(-) strain to test for the role of an infectious agent.

15 their role in infection are dictated by the infectious agent.

16 wing the toxins to move cell-to-cell like an infectious agent.

17 T(CM) cell development were dependent on the infectious agent.

18 e community in preventing the spread of that infectious agent.

19 ongenital infection but in the absence of an infectious agent.

20 nal fluid (CSF) was performed to identify an infectious agent.

21 of genetic diseases and for the detection of infectious agents.

22 c, cytoplasmic, aggregate-prone proteins and infectious agents.

23 tivity needed for front-line defense against infectious agents.

24 n a manner distinct from rapidly replicating infectious agents.

25 cell type to control and eradicate specific infectious agents.

26 velopment of vaccination protocols for other infectious agents.

27 t responses against Y. pestis and many other infectious agents.

28 inhibitor of PCs to prevent PC activation of infectious agents.

29 ich in the case of some pathogens act as the infectious agents.

30 also provide enhanced defense against other infectious agents.

31 disease when challenged with inflammatory or infectious agents.

32 or of intestinal epithelial defenses against infectious agents.

33 ave the potential to combat a broad range of infectious agents.

34 g the characteristics of immune responses to infectious agents.

35 genetic associations in the context of these infectious agents.

36 15% of all cancer cases are attributable to infectious agents.

37 it immune responses to occur against foreign infectious agents.

38 s of countermeasures against these dangerous infectious agents.

39 d asthma; whereas allergens can partly mimic infectious agents.

40 tted through fomites: objects able to convey infectious agents.

41 accines that induce protection against other infectious agents.

42 , represent a major frontier in the study of infectious agents.

43 use not only for cancer therapy but also for infectious agents.

44 in measuring response to other vaccines and infectious agents.

45 ) is a leading cause of birth defects due to infectious agents.

46 strategy by which mammalian hosts respond to infectious agents.

47 platform applicable across a broad range of infectious agents.

48 ide novel avenues for drug targeting against infectious agents.

49 of defense against exposure of the airway to infectious agents.

50 nate might result in an impaired response to infectious agents.

51 les in the modulation of immune responses to infectious agents.

52 may lead to host pathology in the absence of infectious agents.

53 hobionts', to distinguish them from acquired infectious agents.

54 genetic diversity and fight rapidly evolving infectious agents.

55 , as well as by external genotoxic agents or infectious agents.

56 ace between bacterial and archaeal hosts and infectious agents.

57 eceptors recognize external threats posed by infectious agents.

58 r therapeutic tools against a broad range of infectious agents.

59 ainst infections caused by viruses and other infectious agents.

60 ffects of environmental factors derived from infectious agents.

61 n but not for GVL or protective responses to infectious agents.

62 esistance to the environment and immunity to infectious agents.

63 ation network is a common target for diverse infectious agents.

64 diate measurements for the identification of infectious agents.

65 cells and drives the pathogenesis of various infectious agents.

66 medicinal chemistry of these closely related infectious agents.

67 it direct contact between the epithelium and infectious agents.

68 imation, and biocrimes involving tracking of infectious agents.

69 against Mycobacterium tuberculosis and other infectious agents.

70 to hosts and can spread antigens as well as infectious agents.

71 responses to contain and limit the spread of infectious agents.

72 Could it really be an epidemic involving an infectious agent?

73 ho had a positive result for any of the four infectious agents, 16 were positive for two pathogens an

74 arly years, the majority were in response to infectious agents, although environmental problems emerg

75 l outbreaks is desirable to characterize the infectious agent and determine its evolutionary rate.

76 fundamental questions about this intriguing infectious agent and has been broadly applied in researc

77 Low levels of infectious agent and limited, infrequent success of dise

78 Many cases of mastitis involve no known infectious agent and may fundamentally be due to autoimm

79 pecific properties of PrP(Sc) and replicates infectious agent and that DY TME can interfere, or compl

80 o the study of the unorthodox nature of this infectious agent and the molecular mechanism by which th

81 eculated to trigger the syndrome, a specific infectious agent and underlying pathophysiological mecha

82 generating aptamers against a given specific infectious agent and will enable further development of

83 n increased susceptibility of the elderly to infectious agents and an inability to mount protective i

84 and fitness during infection by eliminating infectious agents and by limiting damage caused by patho

85 to various contaminations including toxins, infectious agents and chemical contaminants.

86 ar the body of undesirable particles such as infectious agents and debris.

87 proach for the diagnosis of genetic defects, infectious agents and diseases.

88 low-titer antibodies for detection of other infectious agents and host proteins.

89 the specific sensors used may differ between infectious agents and host species.

90 sensing the presence of foreign antigens and infectious agents and in initiating appropriate immune r

91 n orchestrating innate responses to distinct infectious agents and in maintaining inflammatory respon

92 oop contributes to pathological responses to infectious agents and is therefore tightly regulated.

93 vaccines have been developed by cultivating infectious agents and isolating the inactivated whole pa

94 initial lymph node metastases, as well as by infectious agents and parasites.

95 Tests for infectious agents and pesticides were negative.

96 entify commonality in non-human sequences by infectious agents and putative contamination events, we

97 acteristics, including their ability to bind infectious agents and secrete many immunomodulatory cyto

98 The periodic emergence of new infectious agents and the genetic and antigenic evolutio

99 er, identifying associations between defined infectious agents and the initiation of chronic disease

100 pport annotation of disease processes due to infectious agents and to mutation.

101 y an important role in host defenses against infectious agents and tumors.

102 likely relevant for other viruses (and other infectious agents) and for remote signaling of other pro

103 ifferences underscore the uniqueness of this infectious agent, and its relationship to the coinfectin

104 ferentiation in accord with the nature of an infectious agent, and the contingency of differentiation

105 li, including toxins, venoms, allergens, and infectious agents, and play critical roles in resistance

106 ntinued habitat loss, persistent inbreeding, infectious agents, and possible habitat saturation pose

107 Infectious agents are often considered potential trigger

108 the diversity and geographic distribution of infectious agents are only starting to be investigated.

109 e standard diagnostic approach when specific infectious agents are sought in a clinic specimen.

110 Infectious agents are the third highest human cancer ris

111 Ubiquitin E3 ligases encoded by infectious agents are well known, as are a variety of vi

112 mental difference between Ag presented by an infectious agent as compared with an allograft.

113 decreased exposure at a young age to certain infectious agents as a result of improved hygiene, incre

114 ble to fully understand all aspects of these infectious agents as well as for surveillance of viral p

115 disorder (MDD) to an as-yet uncharacterized infectious agent associated with meningoencephalitis in

116 In an attempt to explore infectious agents associated with nasopharyngeal carcino

117 Case incidence and infectious agent association.

118 Ample evidence exists for the presence of infectious agents at the maternal-fetal interface, often

119 ming the adaptive immune system to eradicate infectious agents, autoimmunity, allergy, and cancer.

120 h the protection of zebrafish larvae against infectious agents before adaptive immunity has developed

121 Most FDA-approved adjuvants for infectious agents boost humoral but not cellular immunit

122 ms such as myalgias and fever, suggesting an infectious agent, but the majority have no identifiable

123 romised not only in their ability to destroy infectious agents, but are at increased risk for death f

124 ve drugs as mycophenolic acid (MPA) and anti-infectious agents, but some PTN remain unexplained.

125 y a critical role in immune defenses against infectious agents, but there have been no reports about

126 Creutzfeldt-Jakob disease agent and that the infectious agent can be present in the spleen without CN

127 is (Mtb) and provided original proof that an infectious agent can cause human disease.

128 Such transmission of infectious agents can occur within the hospital, clinic,

129 e with humans, cross-species transmission of infectious agents can occur.

130 ale mice, nor does it appear to depend on an infectious agent carried vertically in this strain.

131 In response to injurious or infectious agents caspase-1 activating multiprotein comp

132 lesser extent, the airborne transmission of infectious agents caused by the misuse of respiratory pr

133 Staphylococcus aureus is the most common infectious agent causing pyogenic spondylodiscitis.

134 The distributions of most infectious agents causing disease in humans are poorly r

135 ophagous flies could be used to identify the infectious agents circulating in wild vertebrates.

136 Established infectious agents continue to be a major cause of human

137 These results support the concept that an infectious agent contributes to the development of HIV-a

138 eterioration remains elusive and no specific infectious agents could be discerned.

139 The infectious agents covered in this assessment include ade

140 Prevention strategies against infectious agents demand rapid and accurate detection an

141 h the potential to recognize the universe of infectious agents depends on proper regulation of TCR si

142 Infectious agents develop intricate mechanisms to intera

143 source of prions long before exposure to the infectious agent during and after the birthing process o

144 Infectious agents, especially bacteria and their compone

145 Thus, one unique mechanism by which certain infectious agents evade host immune responses may be med

146 immunity may be a general mechanism by which infectious agents exacerbate symptoms associated with ot

147 arly effective for detecting and identifying infectious agents for which routine culture and microsco

148 diverse of these receptors as it recognises infectious agents from a range of pathogenic groups.

149 d to enhanced between-group contact after an infectious agent has been introduced.

150 nal definition, the designation of prions as infectious agents has become problematic.

151 In mammals, chronic diseases resulting from infectious agents have been associated with functional T

152 Infectious agents have been identified as a major cause

153 Many infectious agents have been linked to the development of

154 approach, which should be applicable to many infectious agents, holds promise for the construction of

155 Chemicals, infectious agents, hormone therapy, reproductive history

156 ered which have the potential to act as anti-infectious agents; however, the proteins are toxic and n

157 Arthropods transmit diverse infectious agents; however, the ways microbes influence

158 ants that would be most likely to encounter infectious agents (i.e. foragers) using integrated socia

159 s secreted at increased rates in response to infectious agents, implying that mucins exert a protecti

160 id diagnostics that enable identification of infectious agents improve patient outcomes, antimicrobia

161 mic influenza virus was the most devastating infectious agent in human history, causing fatal pneumon

162 sylated PrP in either the replication of the infectious agent in the periphery or its transport to th

163 blood profiling using RNASeq to discriminate infectious agents in adults with microbiologically defin

164 gens that are among the eight most prevalent infectious agents in hospitals.

165 olecular characterization of known and novel infectious agents in human disease.

166 Their emergence as infectious agents in humans coincided with changes in th

167 eroviruses (EVs) are among the most frequent infectious agents in humans worldwide and represent the

168 management of persistent diarrhea caused by infectious agents in immunocompetent individuals worldwi

169 onsidered, it is important to test for other infectious agents in parallel, as cross-reactivity can o

170 as a chronic inflammatory disease caused by infectious agents in RA seems biologically plausible.

171 literature that supports the involvement of infectious agents in the aetiology of type 1 diabetes in

172 Prions are the infectious agents in the class of fatal neurodegenerativ

173 effective immunity against a wide variety of infectious agents in the environment.

174 e been established as ecologically important infectious agents in the oceans; however, viral infectio

175 ical and mechanistic research in the role of infectious agents in the pathogenesis of or protection f

176 he understanding of the contribution of some infectious agents in the progression of cancers.

177 can result in productive replication of the infectious agents in the recipient cell.

178 Our PCR assays detected DNAs of various infectious agents in tumor specimens, especially HHV6, H

179 ethods for early detection and monitoring of infectious agents in wildlife.

180 osure to infection and the properties of the infectious agent, in addition to the genetic susceptibil

181 New technologies to assess infectious agents include high-throughput methods for pa

182 elial surfaces to repel assault from diverse infectious agents including bacteria, viruses, fungi and

183 can be used to identify a broad spectrum of infectious agents, including bacteria, viruses, yeast, a

184 They also face pressure from infectious agents, including elephant endotheliotropic h

185 so needs to understand broader categories of infectious agents, including pathogenic amoebae and fung

186 tive vaccines developed against a variety of infectious agents, including polio, measles, and hepatit

187 ic cell receptor DC-SIGN by numerous chronic infectious agents, including Porphyromonas gingivalis, i

188 mmune responses are urgently needed for many infectious agents, including the flaviviruses dengue and

189 Attenuated acute infectious agents induce strong CD8(+) T cell immunity,

190 Immunity to infectious agents involves a coordinated response of inn

191 Additionally, timely detection of infectious agents is critical in early diagnosis and tre

192 Timely detection of infectious agents is critical in early diagnosis and tre

193 tion of high-affinity Abs in response to Ags/infectious agents is essential for developing long-lasti

194 oRNAs, but their role in the transmission of infectious agents is less established.

195 y being a first layer in our defense against infectious agents, it is essential for our ability to de

196 The protein-only infectious agents known as prions exist within cellular

197 he influenza virus is one of the most deadly infectious agents known to man and has been responsible

198 oral response, the identity of an antigen or infectious agent leading to the oligoclonal expansion of

199 (IFN) is an early host response to different infectious agents leading to the induction of hundreds o

200 The interaction of macrophages with infectious agents leads to the activation of several sig

201 immune response, triggered in most cases by infectious agents, leads to severe hyperinflammation.

202 iologic, and pathologic evidence supports an infectious agent, likely entering through the lung.

203 cida, mouse cytomegalovirus and DNA, and the infectious agents Listeria monocytogenes and Aspergillus

204 vide evidence to support the hypothesis that infectious agents may act as a comorbidity for AD.

205 epidemiologic data suggest that exposure to infectious agents may be associated with increased MS ri

206 Some studies have suggested that one or more infectious agents may be involved.

207 hypothesis suggests that higher exposure to infectious agents may be one reason for regional differe

208 lation or activation of oncogenes from these infectious agents might be involved in the pathogenesis

209 s should be 'non-self antigens' accompanying infectious agents, might disrupt control of the adaptive

210 he prototypical vaccinia virus, the emerging infectious agent monkeypox virus, and the potential biot

211 Infectious agents must be quickly and efficiently contro

212 the most effective prophylaxis against these infectious agents, no single vaccine simultaneously prov

213 Prions, the infectious agent of scrapie, chronic wasting disease and

214 The infectious agent of the disease anthrax is the spore of

215 iciency virus (FIV) is among the most common infectious agents of cats.

216 ected with Salmonella and Eimeria, two major infectious agents of gastrointestinal diseases of poultr

217 nteroviruses are among the most common viral infectious agents of humans and are primarily transmitte

218 atory reagent contaminants and not bona fide infectious agents of humans underscores the rigorous app

219 and 2 (HSV-1 and HSV-2) are the most common infectious agents of humans.

220 hat respond to host perturbation from either infectious agents or cellular stress.

221 ies using animal models have shown that some infectious agents or products derived from them have the

222 stronaut's ability to prevent acquisition of infectious agents or reactivation of latent infection.

223 on sequencing data could be used to identify infectious agents or structural variants, but there has

224 response, whereas particulate antigens (from infectious agents or tumor cells) remain within brain ti

225 e metabolic adaptation, mediate responses to infectious agents, orchestrate fibrosis in a yin-yang in

226 The inactivation of infectious agents present in diagnostic samples is criti

227 achyrhynchos), have potential to translocate infectious agents (prions) of transmissible spongiform e

228 exposure to cigarette smoke, pollutants, and infectious agents), progression, and consolidation.

229 he brain, and it has been suggested that the infectious agent propagates from cell to cell via a domi

230 ulating that misfolded protein seeds act as "infectious agents" propagating aggregation of nominally

231 The biochemical nature of the prion infectious agent remains unclear.

232 may have resulted from the yet undetermined infectious agent responsible for encephalitis lethargica

233 Prions, the proteinaceous infectious agent responsible for prion diseases, can be

234 Prions are proteinaceous infectious agents responsible for the transmission of pr

235 Prions, the infectious agents responsible for transmissible spongifo

236 These results suggest that exposure to infectious agents should be an important consideration i

237 Hence, depending on the infectious agent, strong recall of mCTLs during secondar

238 ) that are conserved across broad classes of infectious agents such as bacteria and viruses.

239 of omic profiles measuring host response to infectious agents such as influenza viruses at multiple

240 ling functions as a primary pathway by which infectious agents such as lipopolysaccharides (LPSs) cau

241 in the cultivation and management of highly infectious agents, such as acid-fast bacilli and systemi

242 how our microbiome influences the impact of infectious agents, such as C. difficile; how our microbi

243 These findings reveal that systemic infectious agents, such as T. gondii, can induce long-te

244 Intriguingly, several infectious agents, such as Toxoplasma, Legionella, and C

245 public health, as the deliberate release of infectious agents, such smallpox or a related virus, mon

246 hich appears to be the sole component of the infectious agent (termed prion).

247 s were submitted to the state laboratory for infectious agent testing.

248 Norovirus is a highly transmissible infectious agent that causes epidemic gastroenteritis in

249 ssed the special challenges in combatting an infectious agent that causes sporadic outbreaks in resou

250 Prion or PrP(Sc) is a proteinaceous infectious agent that consists of a misfolded and aggreg

251 No infectious agent that could trigger disease was identifi

252 Merkel cell polyomavirus (MCPyV) is a common infectious agent that is likely involved in the etiology

253 th the CNS targeting and the toxicity of the infectious agent that manifests itself as progressive va

254 Prions are notorious protein-only infectious agents that cause invariably fatal brain dise

255 Prions are infectious agents that cause lethal brain diseases; they

256 Prions are infectious agents that cause neurodegenerative diseases

257 Prions are unconventional infectious agents that cause transmissible spongiform en

258 Identification of the infectious agents that circulate within wild animal rese

259 Prions or PrP(Sc) are proteinaceous infectious agents that consist of misfolded, self-replic

260 Prions or PrP(Sc) are proteinaceous infectious agents that consist of misfolded, self-replic

261 limited in identification and implication of infectious agents that pose threats to human health and

262 tive-strand (+)RNA viruses are intracellular infectious agents that reorganize subcellular membranes

263 general mechanism for protecting cells from infectious agents that replicate through a DNA intermedi

264 Prions are unique infectious agents that replicate without a genome and ca

265 on protein (PrP) were first characterized as infectious agents that transmit pathology between indivi

266 Taken together, infectious agents that trigger central nervous system in

267 These results imply that for control of an infectious agent, the time between the distant exposure

268 A distinct class of infectious agents, the virophages that infect giant viru

269 ot be sufficient to understand the spread of infectious agents, their susceptibility to vaccine thera

270 With regard to their susceptibility to infectious agents, they are exquisite NHP models for vir

271 Prions are lethal infectious agents thought to consist of multi-chain form

272 ion of the route of transmission taken by an infectious agent through a host population is critical t

273 of intrauterine infection and the commonest infectious agent to affect allograft recipients, yet the

274 each advance--from the identification of the infectious agent to its culture and study--has been a si

275 nic" Bacillus subtilis, to become lethal and infectious agents to C. elegans.

276 Some studies link exposure to infectious agents to development of brain disorders; oth

277 hways, but also may exert protection against infectious agents to facilitate recovery from acute infl

278 proteins are incorporated directly into the infectious agents, to investigate how proteins interact

279 of animal models to experimentally study how infectious agents transmit between hosts limits our unde

280 The cancer cell is the 'infectious' agent transmitted as an allograft by biting.

281 In the course of combating infectious agents, type I interferon (IFN) needs a timel

282 mucosal sites is critical for the control of infectious agents using these routes to enter the body.

283 provide protective humoral immunity against infectious agents, vaccines that elicit potent CD8 T cel

284 report selective and sensitive detection of infectious agents via electronic detection based on anti

285 Among the major infectious agents, viruses most frequently enter the bra

286 Phylogenetic analyses revealed that this infectious agent was affiliated with the Perkinsea: a pa

287 d adaptive immune mechanisms actively target infectious agents, we hypothesize that its role may be t

288 ry network driving host response to multiple infectious agents, we integrated host transcriptomes and

289 The most frequently identified infectious agents were respiratory viruses, accounting f

290 detection in the BALF by PCR, whereas other infectious agents were undetectable.

291 ly to have a high potential for contact with infectious agents, were reported to infrequently disinfe

292 ical parameters including immune response to infectious agents, which is mediated by activation of th

293 been widely used for rapid identification of infectious agents, which significantly aids physicians i

294 e autophagy machinery controls the burden of infectious agents while simultaneously limiting inflamma

295 HIV is a prime example of an infectious agent whose diagnosis at least in the acute s

296 Satellite RNAs are the smallest infectious agents whose replication is thought to be com

297 standing the causal associations of specific infectious agents with certain B-cell lymphomas has allo

298 though no definitive studies have yet linked infectious agents with IIMs, additional evidence is accu

299 mmune response leads to rapid elimination of infectious agents, with seemingly little long-term impai

300 how that honeybee EIDs are indeed widespread infectious agents within the pollinator assemblage.