ライフサイエンスコーパス: infectious particle

1 leads to the production of spores (suspected infectious particles).

2 tection of as little as one oligomeric PrPSc infectious particle.

3 re form that differs from that of the mature infectious particle.

4 s the envelope proteins of HBV to produce an infectious particle.

5 uced phage replication and the generation of infectious particles.

6 specifically inhibit HCV by interacting with infectious particles.

7 s that sustain viral replication and produce infectious particles.

8 acellular plasma membrane domain to assemble infectious particles.

9 uman stool sample, and produced 10-fold-more infectious particles.

10 some biogenesis pathway for the formation of infectious particles.

11 hannel activity, and, ultimately, release of infectious particles.

12 consistent with the transmission of multiple infectious particles.

13 role for Cys87 and Cys207 in the assembly of infectious particles.

14 NA quantitative detection and the release of infectious particles.

15 uction of human immunodeficiency virus (HIV) infectious particles.

16 in plaque size and a sustained production of infectious particles.

17 tag, which are efficiently incorporated into infectious particles.

18 ing in misleading estimates of the number of infectious particles.

19 ections and were analyzed for APV genome and infectious particles.

20 assembly of foreign structural proteins into infectious particles.

21 tion of DENV-2 genomic RNA and production of infectious particles.

22 and VP5 are exposed on the outer surface of infectious particles.

23 generated about 1800-times fewer background infectious particles.

24 onents, resulting in the formation of mature infectious particles.

25 99 permits assembly, but blocks formation of infectious particles.

26 are responsible for the production of 95% of infectious particles.

27 global structural rearrangements to produce infectious particles.

28 ncapsidated into viral complexes to generate infectious particles.

29 on, viral DNA replication, and production of infectious particles.

30 heir efficient encapsidation into phage-like infectious particles.

31 impacted infections initiated by one or many infectious particles.

32 is the main component of these proteinaceous infectious particles.

33 E (ApoE) was sufficient to permit release of infectious particles.

34 oproteins were efficiently incorporated into infectious particles.

35 six of the MSD mutants were able to produce infectious particles.

36 ect assembly, budding, and maturation of new infectious particles.

37 nd +2L mutants were not capable of producing infectious particles.

38 must incorporate viral glycoproteins to form infectious particles.

39 filter and incubating the filter to release infectious particles.

40 ration of immature vaccinia virus virions to infectious particles.

41 proper virus assembly and for the budding of infectious particles.

42 rticle assembly near the ER but fail to form infectious particles.

43 eins to the formation of SaPI-specific small infectious particles.

44 cdE2 restored NC assembly but not release of infectious particles.

45 y secreted glycoproteins not associated with infectious particles.

46 ls, HCV replicated persistently and released infectious particles.

47 ease (PR) is essential for the production of infectious particles.

48 nd plays a critical role in the formation of infectious particles.

49 viruses (DENV) undergo maturation to become infectious particles.

50 tions in virus RNA synthesis and assembly of infectious particles.

51 rane protein (prM), turning inert virus into infectious particles.

52 howed a fourfold reduction in the release of infectious particles.

53 e titers are not equivalent to the number of infectious particles.

54 a source case of tuberculosis (2) generates infectious particles (3) that survive in the air and (4)

55 p-regulated expression of viral proteins and infectious particles after infection with pathogenic age

56 found that mouse cytomegalovirus can produce infectious particles albeit at a level that does not sus

57 Infectious particles also contain high levels of this pr

58 for the assembly of viral components into an infectious particle and that budding is delayed in Mmut

59 , the majority of E2 was not associated with infectious particles and failed to sediment on sucrose g

60 was necessary for assembly of VSV RNAs into infectious particles and that this signal was supplied b

61 the +3L Env glycoprotein was able to produce infectious particles and was constitutively fusogenic.

62 ion of larger syncytia, higher production of infectious particles, and a more potent cytopathic effec

63 enic after intracranial infection with 10(5) infectious particles, and BNSP-Gag produced a 50%-reduce

64 ts proteolytic processing, the generation of infectious particles, and cell entry.

65 y inactivating both extra- and intracellular infectious particles, and it is nontoxic in vitro and in

66 expression, genome replication, assembly of infectious particles, and spread to other cells.

67 HV structural protein expression, release of infectious particles, and syncytium formation, and endog

68 acting element for the assembly of RNAs into infectious particles, and they delineate RNA sequences t

69 The E2 that was incorporated into infectious particles appeared as a triplet of diffuse ba

70 The RNA genomes in both immature and infectious particles are dimers, and interactions betwee

71 y, HCV RNA, and viral antigens suggests that infectious particles are likely to be present in the lar

72 n ER signal sequence, spikes do not form and infectious particles are not assembled, suggesting an ad

73 In this report, we demonstrate that infectious particles are present both within the infecte

74 gly, "prion" was defined as a "proteinaceous infectious particle." As the concept has expanded to inc

75 tein, plays a critical, but unknown, role in infectious particle assembly.

76 also identified the precise sequence of the infectious particle-associated ORF2 capsid protein.

77 nal 29 nucleotides of Tr allowed assembly of infectious particles but that the 5' terminal 22 nucleot

78 a subclinical phase with constant levels of infectious particles, but the mechanisms underlying this

79 bacmid DNA into Sf9 cells does not generate infectious particles, but this defect was rescued by int

80 ellow fever virus (YFV) replicon into pseudo-infectious particles by supplying the YFV structural pro

81 protein genes for production of single-round infectious particles by way of trans-complementation.

82 or through contaminated water or food by an infectious particle called a spore or oocyst.

83 Small proteinaceous infectious particles called prions cause certain neurode

84 prion strains, wherein chemically identical infectious particles cause distinct phenotypes.

85 ng that the overall architecture of the SPP1 infectious particle coevolved toward high robustness.

86 n model, prions are defined as proteinaceous infectious particles composed solely of this abnormal is

87 Despite normal structural region processing, infectious particles containing genome RNA and capsid pr

88 this method allows the facile generation of infectious particles containing wild-type, mutant, or ch

89 tic effects were inhibited and production of infectious particles decreased by >1,000-fold in the non

90 e for 46 nucleotides, was unable to assemble infectious particles, despite efficient replication.

91 ng late-cycle development yet is secreted by infectious particles during the invasion process.

92 substitution at this position, L172T, yields infectious particles following transfection at 37 degree

93 Even though conidia are the predominant infectious particle for H. capsulatum and are the first

94 ivirus structural proteins and assemble into infectious particles for presentation of lentivirus immu

95 ectivity, that the clearance of physical and infectious particles from a primary, dual-tropic virus i

96 Nevertheless, J10 failed to generate infectious particles from cells in a plasmid-based influ

97 ology became more distorted and the yield of infectious particles from inclusions declined as medium

98 e of an L. pneumophila-infected amoeba as an infectious particle in replicative L. pneumophila lung i

99 ng that subgenomic het DNA was packaged into infectious particles in a concatemeric configuration.

100 e site is not required for the production of infectious particles in a single round of infection, but

101 SEOV RNA and infectious particles in culture media were detected in b

102 e DeltaUS17 mutant virus produced numbers of infectious particles in fibroblasts equal to the numbers

103 ues, we show that attenuated accumulation of infectious particles in presymptomatic disease is preced

104 ate that L. pneumophila-infected amoebae are infectious particles in replicative L. pneumophila infec

105 could be used as a readout of the number of infectious particles in the inoculum.

106 Sizing experiments indicated that infectious particles in vitro and in vivo were >20 nm in

107 itis C virus (HCV) permits the production of infectious particles in vitro.

108 ntration of pIII is increased, the number of infectious particles increases, and their average length

109 an previous estimates of approximately 1,000 infectious particles/infected individual.

110 e spore form of the bacterium represents the infectious particle introduced into a host.

111 In conclusion, the interior of an adenovirus infectious particle is a strongly confined and dense pha

112 ed at a high multiplicity, the production of infectious particles is largely independent of the numbe

113 ntly of the host cell genome and produces no infectious particles, is required for long-term virus pe

114 rom spherical immature forms to brick-shaped infectious particles lacking helical or icosahedral symm

115 nt plays a role for entry of in vivo derived infectious particles likely via usage of apolipoprotein

116 proteins were supplied in trans, >2 x 10(6) infectious particles/ml were produced.

117 n microscopy, the infection is weaker (fewer infectious particles), more transitory, and involves a s

118 s (MIFs) of L. pneumophila are considered as infectious particles most likely capable to cause human

119 the viral and cellular proteins that compose infectious particles of a large complex virus.

120 The endospores of Bacillus anthracis are the infectious particles of anthrax.

121 d, TNcc) replicated efficiently and released infectious particles of approximately 5 log(10) focus-fo

122 The extracellular chlamydial infectious particle, or elementary body (EB), is envelop

123 s the concentration of viral stocks to 10(9) infectious particles per milliliter or more.

124 This system produced nearly 10(3) infectious particles per ml of supernatant, equivalent t

125 This system, which produced more than 10(4) infectious particles per ml of supernatant, would be use

126 -1 envelope generate titers of less than 200 infectious particles per ml.

127 icted virus titers and increased physical to infectious particle (PFU) ratios, with additional data s

128 f a single maturation cleavage site for both infectious particle production and cell entry and emphas

129 Treatment with Quercetin reduced infectious particle production at nontoxic concentration

130 inhibition of adenoviral genome replication, infectious particle production, and cytotoxicity/oncolys

131 artha U(L)21 gene confer defects that affect infectious particle production, causing a delay in sprea

132 gy factors Atg5 or Atg7 had no effect on WNV infectious particle production, indicating that WNV does

133 haracterize the basis for this difference in infectious particle production, we constructed chimeric

134 rescued dimer association, E1 transport, and infectious particle production.

135 l protein-protein interactions important for infectious particle production.

136 ortance of its C-terminal leucine residue in infectious particle production.

137 for protein transport, cell-cell fusion, and infectious-particle production.

138 have the ability to decrease the density of infectious particles, reducing the force of infection an

139 nfection, suggesting that it is required for infectious particle release.

140 HCV) infections may be initiated by multiple infectious particles, resulting in a genetically heterog

141 with asparagine abolished the production of infectious particles, suggesting that P78 may be involve

142 urfold-fewer particles but >1,000-fold-fewer infectious particles than wild-type virus.

143 Each of the E2 Cys mutants produced fewer infectious particles than wild-type virus.

144 ls, a process required for the production of infectious particles that can lead to heritable transpos

145 t continuously phagocytose environmental and infectious particles that invade the alveolar space.

146 on mechanism dominates, which results in non-infectious particles that still retain their packaged DN

147 rein virus replicates in one cell, producing infectious particles that transmit to the next cell via

148 irus (EBV) strain P3HR-1 generate subgenomic infectious particles that, unlike defective interfering

149 found that cell-free HIV-1 crosses PGECs as infectious particles, the efficiency of transcytosis is

150 ential for genome packaging and formation of infectious particles, the minimal requirements of the di

151 with hepatitis B virus (HBV), in addition to infectious particles, there is an excess (typically 1,00

152 owing the three-dimensional structure of the infectious particle to be visualized for the first time.

153 ire 10- to 100-fold higher concentrations of infectious particles to achieve levels of gene transfer

154 believed to act as "Trojan horses" carrying infectious particles to be released on cell necrosis or

155 When a cell was infected by only a single infectious particle, variation in the kinetics of the in

156 ble in that the sizes and composition of the infectious particles vary enormously.

157 ed bacteriophages and herpesviruses assemble infectious particles via an empty precursor capsid (or '

158 cur, an infected individual needs to release infectious particles via respiratory symptoms.

159 We infected mice with spores, that is, the infectious particle, via the pulmonary route and studied

160 ss virion structure, life cycle to reproduce infectious particles, viral protein's nuclear import sig

161 cells to build a factory for assembling new infectious particles (virions), the cytoplasmic virion a

162 Infectious particles were analyzed by transmission elect

163 C. psittaci 6BC infectious particles were electroporated with various co

164 ss all of the HBV proteins and produce fully infectious particles were immunized with a mixture of li

165 tomatitis virus (VSV) ribonucleocapsids into infectious particles were investigated.

166 TNV, the levels of viral RNAs, proteins, and infectious particles were measured for 3 days posttreatm

167 cy of viral gene expression or production of infectious particles were observed.

168 rted 51 nucleotides from the 5' end of 3'CB, infectious particles were produced.

169 The ORF2i protein associated with infectious particles, whereas the ORF2g and ORF2c protei

170 Persistently infected mice produce de novo infectious particles, which can be inhibited with direct

171 We show here that these infectious particles, which we call propagating replicon

172 ells suppressed substantially the release of infectious particles while preserving uninfected cells.

173 r orthopoxviruses depends on the wrapping of infectious particles with a double membrane that enables

174 ulted in rapid accumulation of intracellular infectious particles with release into extracellular flu

175 from distinct serotypes can be mixed to form infectious particles with unique phenotypes.

176 DNA combined with the cell-free synthesis of infectious particles yielded virus whose mouse neuroviru