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1 they appeared to be a minor component of the infiltrate.
2 cedure chest x-ray showed a right lower lobe infiltrate.
3 constituted the majority of the acute immune infiltrate.
4 ed by an eosinophil-predominant inflammatory infiltrate.
5 Seven (47%) had bilateral lung infiltrates.
6 sented with the chief complaint of pulmonary infiltrates.
7 macrophages to form prototypic granulomatous infiltrates.
8 sed tumors were scored for inflammatory cell infiltrates.
9 y AST and ALT levels, as well as immune cell infiltrates.
11 .00 (RAS), 4.00 (control), P = 0.62; without infiltrates, 4.5 (BOS), 0.00 (RAS), 4.56 (control), P =
12 s (median number of LVs per bronchiole: with infiltrates, 5.00 (BOS), 9.00 (RAS), 4.00 (control), P =
13 ouse model, both neutrophils and macrophages infiltrate a human Burkitt's lymphoma xenograft and inhi
14 RG-15 mice did not require preactivation but infiltrated a Burkitt's lymphoma xenograft and efficient
21 breast cancer cell lines for the ability to infiltrate and grow in CSF, a remarkably acellular, mito
22 tute a significant proportion of the initial infiltrate and have the potential to propagate secondary
23 elopment is associated with mononuclear cell infiltrate and high levels of inflammatory cytokine prod
24 fection, with a more pronounced inflammatory infiltrate and increased specific production of IFN-gamm
25 s most frequent between conclusions of other infiltrate and normal for both the reading panel and the
26 e post-trauma microenvironment in which DPCs infiltrate and resident immune cells generate cytotoxic
28 -1.09 mm; P < .001) and a 0.83-mm decreased infiltrate and/or scar size at 3 months after correcting
29 near regression revealed a 1.89-mm decreased infiltrate and/or scar size at 3 weeks (95% CI, -2.69 to
32 be size sensing resulted in large neutrophil infiltrates and clusters in response to small microbes t
34 on patterns with the presence of immune cell infiltrates and immune regulatory molecules, determined
36 a reduced cardiac inflammation (less cardiac infiltrates and suppression of proinflammatory cytokines
37 ferential gene expression patterns unique to infiltrating and resident cells, suggesting unique funct
38 nate the unique composition and functions of infiltrating and resident myeloid cells in GBM, establis
39 oroid, a perivascular choroidal inflammatory infiltrate, and atrophic changes within the optic nerve
40 ssociated with CD8-dominant antitumor immune infiltrate, and together, these contribute to improved c
43 itial endothelium, interstitial inflammatory infiltrates, and glomerular cells.Primary VSMCs were inf
47 lecular signatures of macrophages and T cell infiltrates are relatively high within distinct subsets
49 e growth factor FGF-2, which activates tumor-infiltrating B cells to produce the growth factor IGF-1.
50 e tumor types on both cancer cells and tumor-infiltrating blood vessels, making it a potentially idea
55 a and the proliferation marker Ki67 in tumor-infiltrating CAR T cells when combined with alpha-4-1BB.
58 rway inflammation, approximately 30% of lung-infiltrating CD4 T cells express Foxp3, indicative of Tr
61 ironment, increasing the proportion of tumor-infiltrating CD8(+) T cells and sensitizing tumors to su
70 ltiple tumor clones and assorted stromal and infiltrating cell populations to pooled genomic data.
73 -positive endothelium and underlying SMC and infiltrating cells such as macrophages and leukocytes.
74 ive fibers, with a reduction in inflammatory infiltrates, compared with those in vehicle-treated mice
75 sequelae, possessed a significant leukocytic infiltrate composed primarily of CD4(+) T cells and macr
76 performed transcriptomic profiling of tumor-infiltrating CTLs from treatment-naive patients with lun
77 ll of origin, as APRIL-producing neutrophils infiltrated CXCL-8(+) DLBCL from both germinal center (G
78 notherapeutic regimen caused homing of tumor-infiltrating DC to draining lymph nodes and increased in
79 with placebo after controlling for baseline infiltrate depth (95% CI, 0.22-fold to 0.84-fold; P = .0
80 detecting consolidation, but poor for other infiltrates despite attempts at a rigorous standardizati
82 vels of IL-33 have been associated with deep infiltrating endometriosis, its contribution to the dise
84 No cytogenetic anomalies were found in the infiltrate except in 1 case in which neoplastic cells of
86 assing both cancer cells and multiple immune infiltrates following localized exposure to different ch
89 cancer, we reinforced the concept that tumor-infiltrating gammadeltaT17 cells are endowed with protum
91 rize molecular features of immune cells that infiltrate hepatocellular carcinomas (HCCs) to determine
92 iated microglia and macrophages (GAM), which infiltrate high-grade gilomas, constitute a major cellul
94 that both H03-IPSE and H06-IPSE proteins can infiltrate HTB-9 bladder cells when added exogenously to
97 rize a tumor's neoantigen load, its cadre of infiltrating immune cell types, the T or B cell receptor
98 infiltrating immune cells vs >/=5% of tumour-infiltrating immune cells [IC2/3]), chemotherapy type (v
99 ed tumor onset and increased levels of tumor-infiltrating immune cells comprised of CD11b(+) cells, m
100 , such as keratinocytes and fibroblasts, and infiltrating immune cells expressed CXCL10 at lesional s
101 ancer-promoting cytokine that is secreted by infiltrating immune cells in several cancer models.
102 on on <1% [IC0] or 1% to <5% [IC1] of tumour-infiltrating immune cells vs >/=5% of tumour-infiltratin
104 w reduced expression of markers of cytotoxic infiltrating immune cells, especially CD8(+) T cells, an
108 has demonstrated essential roles for several infiltrating immune populations in the metaplastic progr
111 e original study observed sparse lymphocytic infiltrate in IgG-treated tumors and increased inflammat
113 subsets of myeloid-derived suppressor cells infiltrate in the primary tumour and distant organs with
114 ve increase in a predominantly CD4(+) T-cell infiltrate in the prostate epithelial and stroma of tumo
115 beta and IL-18, reduced myeloid inflammatory infiltrate in the skin and spleen, and substantial decre
116 ly driven by CD8(+) T cells, and immune cell infiltrate in the tumor could be reprogrammed toward a h
117 nduced by beta2GPI in activated T cells that infiltrate in vivo atherosclerotic lesions of primary AP
121 fects of checkpoint blockade on tumor immune infiltrates in human melanoma and murine tumor models.
122 s in many cancer types, these reduced immune infiltrates in muIDH1 glioma tumors may contribute in pa
123 ncept for ERK5 as a target to enhance T-cell infiltrates in prostate cancer, with possible implicatio
125 still contained variably elevated leukocytic infiltrates in their islets when examined at 20-40 wk of
126 ents have shown the presence of inflammatory infiltrates, in some cases with features of B cell-rich
127 ontrol subjects, and islet inflammatory cell infiltrates, independently of the severity of the exocri
128 mposed mainly of macrophages and neutrophils infiltrate infected DRGs and account for the development
129 mposed mainly of macrophages and neutrophils infiltrate infected sensory ganglia and are responsible
130 the RAGE antagonist FPS-ZM1 in mice, and the infiltrated inflammatory cells and cytokines were assess
132 alignant cells increased the number of tumor-infiltrating interferon gamma-producing natural killer (
134 Mesenchymal stromal cells (MSCs) tend to infiltrate into tumors and form a major component of the
136 both wild type and CCR7-/- CD11c-eYFP cells infiltrated into the CNS but cells that lacked CCR7 were
139 ddition, it was found that the released MK2i infiltrated into the tissue with a cumulative manner in
140 l is upregulated in CD8(+) T cells that have infiltrated into transplanted lymphoma tumours, and Grai
142 al findings (n=7) revealed atypical lymphoid infiltrates, Kupffer cell hyperplasia with erythrophagoc
143 urified glomeruli have identified glomerulus-infiltrating leukocyte populations in NZM2328 (NZM) lupu
144 muscle injury, being expressed mostly in the infiltrating leukocytes (CD45(+) cells), including macro
145 p53 activation in TME comprising overt tumor-infiltrating leukocytes (TILeus) induces systemic antitu
148 inhibition did not reduce the proportion of infiltrating leukocytes in the tumor microenvironment bu
149 -pathogenic CD8(+) T cells relative to other infiltrating leukocytes, perhaps preventing further tiss
158 CD4 mRNAs and their relationship with tumor-infiltrating lymphocytes (TIL) and PD-L1 IHC expression.
161 Accumulating evidence indicates that tumor-infiltrating lymphocytes (TILs) are associated with clin
163 however, the antigen specificities of tumor-infiltrating lymphocytes (TILs) are not well understood.
166 and chromatin accessibility in CD8(+) tumor-infiltrating lymphocytes (TILs) that recognize a model t
168 t cancer is associated with increased tumour infiltrating lymphocytes (TILs), however, MAPK activity
169 int inhibitors increases the number of tumor-infiltrating lymphocytes and overall survival after DNA
170 mmuno-PET) can visualize tumors by detecting infiltrating lymphocytes and, through longitudinal obser
173 FACS-based enumeration of intracranial tumor-infiltrating lymphocytes directly correlated with quanti
174 for melanoma, Runx3-deficient CD8(+) tumour-infiltrating lymphocytes failed to accumulate in tumours
175 d PD-L1 levels and reduced numbers of tumour-infiltrating lymphocytes in mouse tumours and in primary
176 Patients with increased numbers of tumor-infiltrating lymphocytes in primary colon tumors and liv
178 ted with significantly lower levels of tumor-infiltrating lymphocytes in triple-negative breast cance
180 found in the draining lymph nodes and tumor-infiltrating lymphocytes of OSCC patients with early or
182 hermore, we show that human and mouse tumour-infiltrating lymphocytes share a core tissue-residency g
183 engineering reinstated Th1 function in tumor-infiltrating lymphocytes that had been functionally disa
184 inhibition can promote recruitment of tumor-infiltrating lymphocytes to the tumor, here we show that
185 l, GSK-3i inhibited PD-1 expression on tumor-infiltrating lymphocytes, while increasing Tbx21 (T-bet)
186 SLOs occurred with a massive accumulation of infiltrated MAC387(+) macrophages, T cells, dendritic ce
187 further demonstrated that higher numbers of infiltrating macrophage iron deposits was associated wit
188 concurrent double depletion of microglia and infiltrated macrophages slightly, but significantly, com
189 ar endothelial growth factor expression, and infiltrating macrophages (Ly6C(+)CD45(high)CD11b(+)).
190 optotic cells and exhibited lower numbers of infiltrating macrophages and neutrophilic granulocytes.
191 the cells of the tumor mass, including both infiltrating macrophages and resident brain microglia.
192 and suppresses tumor development, suggesting infiltrating macrophages as a key source for steatosis-i
193 the innate immune response of microglia and infiltrating macrophages clears up cellular debris and p
194 f CD11b(+)F4/80(-)I-A(-) M2b-like glomerulus-infiltrating macrophages in LN and reinforce macrophages
195 t/beta-catenin as a novel signal produced by infiltrating macrophages induced by steatosis that promo
197 mitate-stimulated CD11b(+)F4/80(low) hepatic infiltrating macrophages, but not CD11b(+)F4/80(high) Ku
198 age in the liver, inflammatory cells such as infiltrating macrophages, T lymphocytes, neutrophils, an
203 was not associated with regions of cellular infiltrates (median number of LVs per bronchiole: with i
204 cs (TPC) in defining the character of highly infiltrating mesenchymal glioblastoma cells (Wnt5a(High)
205 d with poor prognosis and also discriminated infiltrating mesenchymal glioblastoma from poorly motile
206 several derepressed miR-155 targets in tumor-infiltrating, miR-155-deficient CD8(+) T cells, suggesti
207 ouse models, we provide evidence that tumour-infiltrated mMDSCs facilitate tumour cell dissemination
208 l cells and the local resident microglia and infiltrating mo-MPhi within the lesion area, as a mechan
209 lesional macrophages in general and Ly6c(hi) infiltrating monocyte-macrophages in particular, accompa
210 ty was greater on sandier soils, where water infiltrates more readily, and in areas where the maximum
211 on and thereby impair the functions of tumor-infiltrating murine and human myeloid dendritic cells (T
212 lates apoptosis and the numbers of activated infiltrating murine neutrophils but not neutrophil cellu
213 Moreover, we identified changes in tumor-infiltrating myeloid cell (TIM) subsets that likely comp
214 the regulation of PD-L1 expression in tumor-infiltrating myeloid cells and, therefore, reprogramming
215 rs responsible for the protumoral effects of infiltrating myeloid cells can be used to target establi
216 ) reverts the immunosuppressive phenotype of infiltrating myeloid cells, by modulating inflammatory g
217 Glomerular damage mediated by glomerulus-infiltrating myeloid-derived cells is a key pathogenic e
219 Moreover, PD-1 precisely identified marrow-infiltrating, myeloma-specific T cells in a mouse model
220 wo miRNAs are prominently expressed in wound-infiltrated neutrophils and macrophages and play central
221 ing that the immune response is dominated by infiltrating neutrophils and elicits a mixed TH17/TH1 re
224 n individuals with rheumatoid arthritis (RA) infiltrate non-lymphoid tissue sites, maneuver through e
229 e examined the sexual dimorphism in cellular infiltrates of the salivary glands by using functional s
233 itis; however, it did not reduce immune cell infiltrates, or the deposits of IgG and complement in th
235 of skin inflammation and reductions in skin-infiltrating pathogenic effector Th2 cells and TSLP.
236 -methylation programs were acquired in tumor-infiltrating PD-1hi CD8 T cells, and approaches to rever
238 ic GN and severe proteinuria, few glomerulus-infiltrating PMN were found, leaving macrophages and, to
239 ne-derived microparticles released by tissue infiltrating PMNs (PMN-MPs) serve as shuttles to protect
240 ript, is expressed by mononuclear phagocytes infiltrating primary melanoma and is induced by IFNgamma
242 cle-corrected visual acuity (BSCVA), 3-month infiltrate/scar size, corneal perforation, and re-epithe
244 emotely supplying a distinct subset of tumor-infiltrating SiglecF(high) neutrophils, which exhibit ca
245 or fabricating WCu alloys using spark plasma infiltrating sintering of copper-coated graphene (Cu@Gr)
246 These analyses reveal a spectrum of tumor-infiltrating T cell populations that are highly similar
248 tion) revealed that a discrete proportion of infiltrating T cells and B cells underwent proliferation
252 s study, we tested the hypothesis that tumor-infiltrating T cells could be more effectively activated
253 ed the persistence and accumulation of tumor-infiltrating T cells in vivo, compared with the parental
258 h DCB displayed a higher proportion of tumor-infiltrating T lymphocytes (TIL) (n = 24, Mann-Whitney p
260 de increases IFNgamma-producing CD8(+) tumor-infiltrating T lymphocytes and results in a profound ext
263 4/6 inhibition significantly increased tumor-infiltrating T-cell activation and cytotoxicity and decr
264 n of glomerulonephritis and diminished renal-infiltrating Tfh and Th1 cells, and improved overall sur
266 of the oral lesions revealed a subepithelial infiltrate that was primarily composed of CD3- and CD4-p
269 t a later time point, inflammatory monocytes infiltrate the spleen parenchyma but remain mainly intra
272 atrix protein synthesis, and the macrophages infiltrating the dystrophic muscles were the source of m
275 nterstitial macrophages (IMs) from monocytes infiltrating the lung or mobilized from the spleen.
276 flammatory monocytic cells were not observed infiltrating the skin of DSS cases on whole-mount histol
277 cMy-mOVA-OT-II mice, yet more CD3(+) T cells infiltrated their myocardium when compared with TAC-oper
278 dies that were based on genotypes from tumor-infiltrated tissue to examine whether genotyping errors
280 Acute hypoxemic patients with bilateral infiltrates treated with high-flow nasal cannula present
282 cgammaRs led to effective depletion of tumor-infiltrating Treg cells, increased effector to Treg cell
283 comparable with that of mouse GITR in tumor-infiltrating Tregs despite being drastically lower in ot
284 4166 downregulated FOXP3 mRNA in human tumor infiltrating Tregs, suggesting that, in addition to enha
289 ions showed higher T cell and dendritic cell infiltrates vs. CONTROLS: Seven hundred and forty-three
293 nto CL group; 1 eye (8%) had sterile corneal infiltrates, which did not affect the final visual acuit
294 resulted in minimal to moderate lymphocytic infiltrate, while the original study observed sparse lym
295 d single-walled carbon nanotube (SWCNT) film infiltrated with 2,2,7,-7-tetrakis(N,N-di-p-methoxypheny
299 e, mild B-lymphocyte and moderate macrophage infiltrates, with perivascular predominance as well as d
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