ライフサイエンスコーパス: infiltrating

1 gulated in type 1 and type 2 diabetes and in infiltrating activated immune cells.

2 iated metastatic cervical cancer after tumor-infiltrating adoptive T cell therapy.

3 ferential gene expression patterns unique to infiltrating and resident cells, suggesting unique funct

4 nate the unique composition and functions of infiltrating and resident myeloid cells in GBM, establis

5 Interestingly, tumor-infiltrating and tumor-draining lymph node NK cells disp

6 This delay correlated with increased infiltrating antitumor macrophages.

7 e growth factor FGF-2, which activates tumor-infiltrating B cells to produce the growth factor IGF-1.

8 elevated immunoglobulin expression by tumor-infiltrating B cells, NF-kappaB activation, and increase

9 The presence of tumor-infiltrating B lymphocytes has been linked to a favorabl

10 e tumor types on both cancer cells and tumor-infiltrating blood vessels, making it a potentially idea

11 We characterized T cells infiltrating both breast cancer tumors and the surroundi

12 esenchymal glioblastoma TPC suppressed their infiltrating capability.

13 a and the proliferation marker Ki67 in tumor-infiltrating CAR T cells when combined with alpha-4-1BB.

14 Tumor-infiltrating CCR5(+) MDSCs displayed higher immunosuppre

15 The occurrence of a major glomerulus-infiltrating CD11b(+)F4/80(-)I-A(-) macrophage populatio

16 cells form prolonged interactions with graft-infiltrating CD11c(+) cells; their differentiation is sk

17 L2 or MIF expression and the number of tumor-infiltrating CD33(+) MDSCs (P<0.01).

18 Although the majority of infiltrating CD4 cells appeared functionally inactive, t

19 On the contrary, only approximately 10% of infiltrating CD4 T cells express Foxp3 during neutrophil

20 rway inflammation, approximately 30% of lung-infiltrating CD4 T cells express Foxp3, indicative of Tr

21 Tumor-infiltrating CD4(+) and CD8(+) T cells in patients with

22 contrast to all other affected organs, where infiltrating CD4(+) cells are predominant.

23 ed in C3aR-deficient mice and returned tumor-infiltrating CD4(+) T cells to control levels.

24 The frequency of islet-infiltrating CD8 T cells was reduced in NOD.Tnfrsf9(-/-)

25 were also expressed on human PD1(hi) tumour-infiltrating CD8 T cells.

26 vation and effector genes expressed by tumor-infiltrating CD8(+) and CD4(+) T cells, and tumor-associ

27 ry, the HFD liver showed increased necrosis, infiltrating CD8(+) cells, alanine aminotransferase, and

28 ironment, increasing the proportion of tumor-infiltrating CD8(+) T cells and sensitizing tumors to su

29 d with PD-L1 suppression, increases in tumor-infiltrating CD8(+) T cells and tumor cell killing.

30 The percentage of tumor-infiltrating CD8(+) T cells coexpressing PD-1 and Tim-3

31 Remarkably, infiltrating CD8(+) T cells do not cause tissue damage i

32 Here we describe a subset of tumor-infiltrating CD8(+) T cells marked by high expression of

33 Brain-infiltrating CD8(+) T cells represent an activated subse

34 Tumor-infiltrating CD8(+) T cells with high CD39 expression ex

35 ates the expansion and cytotoxicity of tumor-infiltrating CD8+ T cells and inhibits inflammatory CD4+

36 Consequently, our data indicated infiltrating CD8+ T cells could promote the proliferatio

37 ative abundance of partially exhausted tumor-infiltrating CD8+ T cells predicts response to anti-PD-1

38 otein expression (immunohistochemistry), and infiltrating cell populations (flow cytometry).

39 ltiple tumor clones and assorted stromal and infiltrating cell populations to pooled genomic data.

40 Current imaging modalities based on the infiltrating cell types are briefly discussed.

41 The initial infiltrating cells accumulate perivascularly in close pr

42 nd the functional immune reactivity of tumor-infiltrating cells after ex vivo exposure to ICB.

43 oth muscle cell proliferation, and had fewer infiltrating cells but retained endothelialization.

44 epresents a novel means for protecting tumor-infiltrating cells from tumor-associated oxidative stres

45 s in GBM, establishing a rationale to target infiltrating cells in this neoplasm.

46 -positive endothelium and underlying SMC and infiltrating cells such as macrophages and leukocytes.

47 resident muscle stem cells, hepatocytes, and infiltrating cells.

48 ing monocytes, as well as effector monocytes infiltrating certain sites of inflammation, such as the

49 define the 'molecular fingerprint' of tumor-infiltrating CTLs and identify potentially new targets f

50 performed transcriptomic profiling of tumor-infiltrating CTLs from treatment-naive patients with lun

51 ls can nonetheless be efficiently cleared by infiltrating cytotoxic T lymphocytes (CTL) without compr

52 notherapeutic regimen caused homing of tumor-infiltrating DC to draining lymph nodes and increased in

53 nerve regeneration and reduced the number of infiltrating DCs, which were a major source of ciliary n

54 A 0.6 x 0.5 cm Nottingham grade 1 infiltrating ductal carcinoma was removed from the right

55 vels of IL-33 have been associated with deep infiltrating endometriosis, its contribution to the dise

56 About 8.8% +/- 4.8% of the infiltrating eosinophils exhibited EETs in patients' nas

57 nd we were able to confirm pyroptosis in the infiltrating eosinophils.

58 ntly induces the expansion of specific tumor-infiltrating exhausted-like CD8 T cell subsets.

59 st cancers demonstrated high levels of tumor-infiltrating FOXP3+ cells (38%; range, 35%-41%).

60 cancer, we reinforced the concept that tumor-infiltrating gammadeltaT17 cells are endowed with protum

61 Tracking and eradicating infiltrating GBM cells and tumor microsatellites is of u

62 ed increase in glomerular IgG deposition and infiltrating granulocytes, much more severe glomerulonep

63 ay therefore affect the composition of tumor-infiltrating hematopoietic cells and subsequent tumor pr

64 that appear to perform similar functions in infiltrating host cells.

65 oliferation and also provided attachment for infiltrating host cells.

66 diversity of the T cell receptors (TCRs) of infiltrating IFN-gamma and IL-17A-producing T cells in m

67 OPD is driven by a Th1 response activated by infiltrating ILC1, NK, and LTi cells.

68 Second, infiltrating immune cell populations were decreased in v

69 rize a tumor's neoantigen load, its cadre of infiltrating immune cell types, the T or B cell receptor

70 0%, TC1>/=1% and <5%, and TC0<1%) and tumour-infiltrating immune cells (as percentage of tumour area:

71 -L1 expression on tumor cells (TC) and tumor-infiltrating immune cells (IC), abundance of tumor-infil

72 The PD-L1 expression status on infiltrating immune cells (ICs) in the tumour microenvir

73 PD-L1 expression on tumour-infiltrating immune cells (ICs) was assessed prospective

74 infiltrating immune cells vs >/=5% of tumour-infiltrating immune cells [IC2/3]), chemotherapy type (v

75 which may be due to an observed decrease in infiltrating immune cells and downregulation of barrier

76 elop a computational approach to study tumor-infiltrating immune cells and their interactions with ca

77 ed tumor onset and increased levels of tumor-infiltrating immune cells comprised of CD11b(+) cells, m

78 , such as keratinocytes and fibroblasts, and infiltrating immune cells expressed CXCL10 at lesional s

79 ancer-promoting cytokine that is secreted by infiltrating immune cells in several cancer models.

80 on on <1% [IC0] or 1% to <5% [IC1] of tumour-infiltrating immune cells vs >/=5% of tumour-infiltratin

81 uencies of effector T cells (Teff) and graft infiltrating immune cells were measured at 2 weeks postt

82 1/2/3 (>/=1% PD-L1 on tumour cells or tumour-infiltrating immune cells).

83 ation of HIF-1alpha in circulating and liver-infiltrating immune cells, but not in hepatocytes, befor

84 w reduced expression of markers of cytotoxic infiltrating immune cells, especially CD8(+) T cells, an

85 Among tumor-infiltrating immune cells, tumor-associated macrophages

86 e immunological response by interacting with infiltrating immune cells.

87 n colonic epithelium potentially assisted by infiltrating immune components.

88 has demonstrated essential roles for several infiltrating immune populations in the metaplastic progr

89 We showed imaging of infiltrating immunocytes in BLT mice that spontaneously

90 ncomitantly with a decrease in the number of infiltrating inflammatory macrophages and an increase in

91 result of neuronal death triggered by brain-infiltrating inflammatory monocytes.

92 This study suggests that biasing the infiltrating inflammatory/immune cellular milieu after i

93 alignant cells increased the number of tumor-infiltrating interferon gamma-producing natural killer (

94 HBV-infected HIS-HUHEP livers contained infiltrating Kupffer cells, mature activated natural kil

95 urified glomeruli have identified glomerulus-infiltrating leukocyte populations in NZM2328 (NZM) lupu

96 n LysMcreTNF(fl/fl) mice, despite comparable infiltrating leukocyte populations.

97 slets displaying insulitis to total islets), infiltrating leukocyte subtypes, and beta-cell and alpha

98 muscle injury, being expressed mostly in the infiltrating leukocytes (CD45(+) cells), including macro

99 p53 activation in TME comprising overt tumor-infiltrating leukocytes (TILeus) induces systemic antitu

100 on deconvolution approach for studying tumor-infiltrating leukocytes (TILs) in 23 cancer types profil

101 and adaptive cellular immune response, with infiltrating leukocytes and a marked eosinophilia (49%).

102 rs with high levels of CCR4-expressing tumor-infiltrating leukocytes and abnormal plasma CCR4 ligand

103 t manipulates the activation status of tumor-infiltrating leukocytes and renders them immunocompromis

104 Infiltrating leukocytes are responsible for driving the

105 Immunophenotyping of skin-infiltrating leukocytes confirmed substantial infiltrati

106 inhibition did not reduce the proportion of infiltrating leukocytes in the tumor microenvironment bu

107 Analysis of tumor-infiltrating leukocytes revealed significant reduction o

108 -pathogenic CD8(+) T cells relative to other infiltrating leukocytes, perhaps preventing further tiss

109 t occurring in response to stimuli by tissue-infiltrating leukocytes.

110 a less extent, dendritic cells as the major infiltrating leukocytes.

111 eribronchial regions, which were enriched in infiltrating leukocytes.

112 seases by reducing the recruitment of tissue-infiltrating leukocytes.

113 We demonstrated here that FL-infiltrating LN and BM stromal cells overexpressed CXCL1

114 Infiltrating low grade gliomas (LGGs) are heterogeneous

115 ecifying important steps of regeneration: 1) infiltrating Ly6C(pos) macrophages expressed acute-phase

116 thout 1,200 cGy TBI before transfer of tumor-infiltrating lymphcytes.

117 We isolated tumor-infiltrating lymphocytes (TIL) and intra-hepatic lymphoc

118 CD4 mRNAs and their relationship with tumor-infiltrating lymphocytes (TIL) and PD-L1 IHC expression.

119 Tumor-infiltrating lymphocytes (TIL) are potent mediators of a

120 Recent studies have found that tumor-infiltrating lymphocytes (TIL) expressing PD-1 can recog

121 The presence of tumor-infiltrating lymphocytes (TIL) is a favorable prognostic

122 self-tolerance often result in CD8(+) tumor-infiltrating lymphocytes (TIL) with a hypofunctional phe

123 Accumulating evidence indicates that tumor-infiltrating lymphocytes (TILs) are associated with clin

124 It is well known that CD8(+) tumor-infiltrating lymphocytes (TILs) are correlated with posi

125 however, the antigen specificities of tumor-infiltrating lymphocytes (TILs) are not well understood.

126 ne if adoptive transfer of autologous tumour-infiltrating lymphocytes (TILs) could mediate regression

127 a unique ILC population that inhibits tumor-infiltrating lymphocytes (TILs) from high-grade serous t

128 represented a large proportion of the tumor-infiltrating lymphocytes (TILs) in claudin-low tumors, a

129 High quantities of tumour-infiltrating lymphocytes (TILs) in primary HER2-positive

130 Although the presence of tumor-infiltrating lymphocytes (TILs) indicates an endogenous

131 However, the evaluation of tumor-infiltrating lymphocytes (TILs) relies on histopathologi

132 and chromatin accessibility in CD8(+) tumor-infiltrating lymphocytes (TILs) that recognize a model t

133 Percentage of tumor cells and tumor-infiltrating lymphocytes (TILs) with PD-L1 expression, i

134 rvival, an immune response linked with tumor-infiltrating lymphocytes (TILs), and a repressed CSC met

135 rating immune cells (IC), abundance of tumor-infiltrating lymphocytes (TILs), and expression of the i

136 t cancer is associated with increased tumour infiltrating lymphocytes (TILs), however, MAPK activity

137 freshly isolated CD8(+)/CD103(+) lung tumor-infiltrating lymphocytes and CD103(+) tumor-specific CTL

138 esponded with significant increases in tumor-infiltrating lymphocytes and increased expression of lym

139 y endpoints included the generation of tumor-infiltrating lymphocytes and modulation of immune cell p

140 int inhibitors increases the number of tumor-infiltrating lymphocytes and overall survival after DNA

141 mmuno-PET) can visualize tumors by detecting infiltrating lymphocytes and, through longitudinal obser

142 Tumor-infiltrating lymphocytes appear to be a predictor of sur

143 The mechanisms through which infiltrating lymphocytes cause disease remain unknown.

144 Tumor-infiltrating lymphocytes coexpressed PD-1 with the inhib

145 ation; P < .05) that was accompanied by more infiltrating lymphocytes compared with sham operation (7

146 FACS-based enumeration of intracranial tumor-infiltrating lymphocytes directly correlated with quanti

147 for melanoma, Runx3-deficient CD8(+) tumour-infiltrating lymphocytes failed to accumulate in tumours

148 kers in circulating blood cells and in tumor-infiltrating lymphocytes from patients with resected sta

149 d PD-L1 levels and reduced numbers of tumour-infiltrating lymphocytes in mouse tumours and in primary

150 Patients with increased numbers of tumor-infiltrating lymphocytes in primary colon tumors and liv

151 Approaches to enhance tumor-infiltrating lymphocytes in the tumor bed may substantia

152 The presence of tumor-infiltrating lymphocytes in triple-negative breast cance

153 ted with significantly lower levels of tumor-infiltrating lymphocytes in triple-negative breast cance

154 Systematic interrogation of tumor-infiltrating lymphocytes is key to the development of im

155 found in the draining lymph nodes and tumor-infiltrating lymphocytes of OSCC patients with early or

156 over, CCR6(+) Treg cells isolated from tumor-infiltrating lymphocytes or draining lymph nodes maintai

157 In conclusion, we show that pituitary-infiltrating lymphocytes proliferate in situ during AH,

158 hermore, we show that human and mouse tumour-infiltrating lymphocytes share a core tissue-residency g

159 engineering reinstated Th1 function in tumor-infiltrating lymphocytes that had been functionally disa

160 chemotherapy or radiation can increase tumor-infiltrating lymphocytes that overcome resistance to imm

161 ely 1.11x10(11) HLA-C*08:02-restricted tumor-infiltrating lymphocytes that were composed of four diff

162 inhibition can promote recruitment of tumor-infiltrating lymphocytes to the tumor, here we show that

163 The number of tumor-infiltrating lymphocytes was also reduced in LKB1-defici

164 density methods, peripheral blood, and graft infiltrating lymphocytes were isolated and phenotyped.

165 ts high levels of tumour neoantigens, tumour-infiltrating lymphocytes, and checkpoint regulators.

166 data on new biomarker strategies with tumour-infiltrating lymphocytes, mutational burden, immune gene

167 l, GSK-3i inhibited PD-1 expression on tumor-infiltrating lymphocytes, while increasing Tbx21 (T-bet)

168 further demonstrated that higher numbers of infiltrating macrophage iron deposits was associated wit

169 ar endothelial growth factor expression, and infiltrating macrophages (Ly6C(+)CD45(high)CD11b(+)).

170 optotic cells and exhibited lower numbers of infiltrating macrophages and neutrophilic granulocytes.

171 the cells of the tumor mass, including both infiltrating macrophages and resident brain microglia.

172 In glioma, microglia and infiltrating macrophages are exposed to factors that for

173 and suppresses tumor development, suggesting infiltrating macrophages as a key source for steatosis-i

174 the innate immune response of microglia and infiltrating macrophages clears up cellular debris and p

175 Finally, NLRP3 expression in tumor-infiltrating macrophages correlated with survival, lymph

176 oss-talk of the local muscle tissue with the infiltrating macrophages during tissue regeneration upon

177 Additionally, tumor-infiltrating macrophages from sh-a2 tumors showed a redu

178 f CD11b(+)F4/80(-)I-A(-) M2b-like glomerulus-infiltrating macrophages in LN and reinforce macrophages

179 Mechanistically, we found that the graft-infiltrating macrophages in LysM(C)(re) Mtor(fl/fl) reci

180 t/beta-catenin as a novel signal produced by infiltrating macrophages induced by steatosis that promo

181 Although infiltrating macrophages influence many pathological pro

182 ROS generation by infiltrating macrophages involves multiple mechanisms, i

183 Hence, MR imaging cell tracking of infiltrating macrophages may have predictive value in de

184 Activated, infiltrating macrophages were associated with HIV RNA.

185 cells in vivo, labeling activated microglia, infiltrating macrophages, and neutrophils, whereas there

186 mitate-stimulated CD11b(+)F4/80(low) hepatic infiltrating macrophages, but not CD11b(+)F4/80(high) Ku

187 age in the liver, inflammatory cells such as infiltrating macrophages, T lymphocytes, neutrophils, an

188 Infiltrating macrophages/monocytes constituted approxima

189 Bone marrow-derived infiltrating macrophages/monocytes were recruited to the

190 ells was associated with a higher density of infiltrating mature DC and effector memory T-cell subset

191 Immunohistochemical characterization of infiltrating MCs and the effects of gliadin peptides on

192 tricted inflammation of EAE by reprogramming infiltrating MCs into antiinflammatory myeloid cells via

193 Infiltrating MCs were associated with the severity of mu

194 At day 7, half of the infiltrating MDMs exhibited a bias toward a proinflammat

195 ), we found robust phenotypic changes in the infiltrating MDMs over time and demonstrated that MDMs a

196 Importantly, premetastatic liver-infiltrating MDSCs induced tumor cell survival without i

197 Targeted therapy against mCRPC-infiltrating MDSCs, using multikinase inhibitors such as

198 cs (TPC) in defining the character of highly infiltrating mesenchymal glioblastoma cells (Wnt5a(High)

199 d with poor prognosis and also discriminated infiltrating mesenchymal glioblastoma from poorly motile

200 several derepressed miR-155 targets in tumor-infiltrating, miR-155-deficient CD8(+) T cells, suggesti

201 l cells and the local resident microglia and infiltrating mo-MPhi within the lesion area, as a mechan

202 oid cells, including activated microglia and infiltrating monocyte-derived macrophages (mo-MPhi).

203 Infiltrating monocyte-derived macrophages aggravate APAP

204 In the peripheral nervous system, infiltrating monocyte-derived macrophages, which use the

205 lesional macrophages in general and Ly6c(hi) infiltrating monocyte-macrophages in particular, accompa

206 The role of infiltrating monocytes during the early phase of ALF is

207 is characterized by an in situ transition of infiltrating monocytes from an inflammatory (Ly6C(high)

208 These findings indicate the role played by infiltrating monocytes in maintaining myeloid cell homeo

209 evaluated by immunohistochemistry, on tumor infiltrating mononuclear cells (TIMCs) and tumor cells w

210 r 1 (S1pr1) alone in CD11b(hi) CD206(+) TAMs infiltrating mouse breast tumors prevents pulmonary meta

211 r in vivo to tumor cells in solid tumors via infiltrating MPs, regulate tumor cell gene expression, a

212 as recently found to be upregulated on tumor-infiltrating murine (CD11c(+)CD11b(+)CD8(-)CD209a(+)) an

213 on and thereby impair the functions of tumor-infiltrating murine and human myeloid dendritic cells (T

214 lates apoptosis and the numbers of activated infiltrating murine neutrophils but not neutrophil cellu

215 Moreover, we identified changes in tumor-infiltrating myeloid cell (TIM) subsets that likely comp

216 the regulation of PD-L1 expression in tumor-infiltrating myeloid cells and, therefore, reprogramming

217 rs responsible for the protumoral effects of infiltrating myeloid cells can be used to target establi

218 local nitric oxide (NO) production by tumor-infiltrating myeloid cells is important for adoptively t

219 compartments, including satellite cells, and infiltrating myeloid cells upon tissue damage.

220 ) reverts the immunosuppressive phenotype of infiltrating myeloid cells, by modulating inflammatory g

221 cognate receptor--was upregulated in tumour-infiltrating myeloid cells.

222 Glomerular damage mediated by glomerulus-infiltrating myeloid-derived cells is a key pathogenic e

223 PTEN-deficient sarcomas revealed infiltrating myeloid-derived hematopoietic cells, partic

224 complement C5a receptor 1 expressed on tumor infiltrating myeloid-derived suppressor cells.

225 Moreover, PD-1 precisely identified marrow-infiltrating, myeloma-specific T cells in a mouse model

226 ing that the immune response is dominated by infiltrating neutrophils and elicits a mixed TH17/TH1 re

227 Tumor-infiltrating neutrophils have been implicated in maligna

228 Syk was expressed by infiltrating neutrophils, macrophages, and platelets in

229 n is the production of oxidized compounds by infiltrating neutrophils.

230 ced proinflammatory signaling in macrophages infiltrating pancreatic islets.

231 of skin inflammation and reductions in skin-infiltrating pathogenic effector Th2 cells and TSLP.

232 -methylation programs were acquired in tumor-infiltrating PD-1hi CD8 T cells, and approaches to rever

233 Tumor-infiltrating PD-L1(+) cells isolated from tumor-bearing

234 ic GN and severe proteinuria, few glomerulus-infiltrating PMN were found, leaving macrophages and, to

235 ne-derived microparticles released by tissue infiltrating PMNs (PMN-MPs) serve as shuttles to protect

236 crophages, but also an accumulation of tumor-infiltrating polymorphonuclear mononuclear cells caused

237 ript, is expressed by mononuclear phagocytes infiltrating primary melanoma and is induced by IFNgamma

238 a significant increase in the number of CNS-infiltrating proinflammatory leukocytes compared with WT

239 s mediated by astrocytes, microglia, and CNS-infiltrating proinflammatory monocytes.

240 strength contaminant plumes are displaced by infiltrating rainwater.

241 ssues, SH2D4A was positively associated with infiltrating regulatory and cytotoxic T-cell populations

242 Infiltrating river water becomes anoxic in the uppermost

243 emotely supplying a distinct subset of tumor-infiltrating SiglecF(high) neutrophils, which exhibit ca

244 Our data suggest that this infiltrating sIL-6R, which is needed for IL-6 trans-sign

245 or fabricating WCu alloys using spark plasma infiltrating sintering of copper-coated graphene (Cu@Gr)

246 T follicular helper (TFH) cells and infiltrating stromal cells have been shown to favor FL B

247 the vagina characterized by neutrophils and infiltrating submucosal plasma cells consisting primaril

248 These analyses reveal a spectrum of tumor-infiltrating T cell populations that are highly similar

249 ckade targets only specific subsets of tumor-infiltrating T cell populations.

250 tion) revealed that a discrete proportion of infiltrating T cells and B cells underwent proliferation

251 hich was accompanied by activation of kidney-infiltrating T cells and cytokine production.

252 l analyses, that neoantigen-specific, tumour-infiltrating T cells are highly heterogeneous and are su

253 filing reveals that antigen-specific, tumour-infiltrating T cells are highly heterogeneous.

254 Infiltrating T cells co-localized with dendritic cells i

255 rent tumor immunogenicity, with variation in infiltrating T cells contributing to differences in obje

256 s study, we tested the hypothesis that tumor-infiltrating T cells could be more effectively activated

257 at proinsulin peptides are targeted by islet-infiltrating T cells from patients with type 1 diabetes.

258 ed the persistence and accumulation of tumor-infiltrating T cells in vivo, compared with the parental

259 ogramming of the altered metabolism of tumor-infiltrating T cells might represent a potential strateg

260 Tumor-infiltrating T cells play an important role in many canc

261 Dysregulation of this pathway in tumor-infiltrating T cells results in diminished anti-tumor im

262 Tumor-infiltrating T cells showed a progressive loss of PPAR-g

263 nown about human antigenic targets for islet-infiltrating T cells.

264 d but not the intermittent migration of lung-infiltrating T cells.

265 ating CD45RO(+) memory T cells and most skin-infiltrating T cells.

266 h DCB displayed a higher proportion of tumor-infiltrating T lymphocytes (TIL) (n = 24, Mann-Whitney p

267 understand the molecular correlates of tumor-infiltrating T lymphocytes (TIL) in squamous cell carcin

268 es the proliferation of both naive and tumor-infiltrating T lymphocytes (TIL).

269 How tumor-infiltrating T lymphocytes (TILs) adapt to the metabolic

270 de increases IFNgamma-producing CD8(+) tumor-infiltrating T lymphocytes and results in a profound ext

271 -target suppression of the activity of tumor-infiltrating T lymphocytes.

272 We report a heterogeneous population of infiltrating T lymphocytes.

273 nt molecules PDL1 and CTLA4, increased tumor-infiltrating T regulatory cells, and decreased natural k

274 4/6 inhibition significantly increased tumor-infiltrating T-cell activation and cytotoxicity and decr

275 , how the underlying structure of the glioma-infiltrating T-cell population differs from that of the

276 ed tumor samples showed significantly higher infiltrating T-cells and increased blood levels of numer

277 n of glomerulonephritis and diminished renal-infiltrating Tfh and Th1 cells, and improved overall sur

278 Macrophages infiltrating the allografts are heterogeneous, consistin

279 of IFNgamma- and IL-17-producing CD4 T cells infiltrating the CNS tissues are greater in these mice.

280 der to limit the number of activated T cells infiltrating the CNS.

281 atrix protein synthesis, and the macrophages infiltrating the dystrophic muscles were the source of m

282 METHODS AND Leukocytes infiltrating the failing heart were analyzed by a multis

283 T cells infiltrating the injured heart significantly upregulated

284 e peripheral T cell repertoire is of T cells infiltrating the islets.

285 nterstitial macrophages (IMs) from monocytes infiltrating the lung or mobilized from the spleen.

286 ALL cells that had entered the CNS and were infiltrating the meninges were characterized by high exp

287 ial epithelium and inflammatory immune cells infiltrating the respiratory epithelium of mice exposed

288 flammatory monocytic cells were not observed infiltrating the skin of DSS cases on whole-mount histol

289 ture CD33(+) immunosuppressive myeloid cells infiltrating the tumors.

290 d to Treg cells from healthy tissues, tumour-infiltrating Treg cells downregulated Foxo1 target genes

291 25 expression is largely restricted to tumor-infiltrating Treg cells in mice and humans.

292 cgammaRs led to effective depletion of tumor-infiltrating Treg cells, increased effector to Treg cell

293 Liver-infiltrating Treg reside close to bile ducts and cocultu

294 comparable with that of mouse GITR in tumor-infiltrating Tregs despite being drastically lower in ot

295 Indeed, lung-infiltrating Tregs exhibit phenotypic and functional fea

296 4166 downregulated FOXP3 mRNA in human tumor infiltrating Tregs, suggesting that, in addition to enha

297 The low apoptosis rate of infiltrating TTP-deficient neutrophils was comparable to

298 Cytotoxic T cells infiltrating tumors are thought to utilize HIF transcrip

299 Immune cells infiltrating tumors can have important impact on tumor p

300 Since both MCT and MCTC infiltrating tumour islets in ES NSCLC patients express