ライフサイエンスコーパス: inflammatory lesion

1 50.3%) of benign lesions (including 11 of 12 inflammatory lesions).

2 primary or metastatic tumors, infections, or inflammatory lesions).

3 block migration of leukocytes to the site of inflammatory lesion.

4 an effective means to control virus-induced inflammatory lesions.

5 y a massive infiltration of neutrophils into inflammatory lesions.

6 neurons and later in infiltrating T cells in inflammatory lesions.

7 ce that received RCA I alone did not develop inflammatory lesions.

8 a shift in tissue trafficking and accrual in inflammatory lesions.

9 ss and can contribute to the pathogenesis of inflammatory lesions.

10 remitting spastic paraplegia and hemorrhagic inflammatory lesions.

11 nt objective was to control the mucogingival inflammatory lesions.

12 an outcome expected to result in more severe inflammatory lesions.

13 interaction to regulate virus-induced immuno-inflammatory lesions.

14 considered a white matter disease with focal inflammatory lesions.

15 g of arginase I, predominantly in submucosal inflammatory lesions.

16 loping gradually following the appearance of inflammatory lesions.

17 -specific T cells in the initiation of these inflammatory lesions.

18 recruitment and the migration of cells into inflammatory lesions.

19 nal to EAE effector T cells found within the inflammatory lesions.

20 otype resembled that of T cells infiltrating inflammatory lesions.

21 ins during myeloid cell-cell interactions in inflammatory lesions.

22 destruction of connective tissue in chronic inflammatory lesions.

23 therapeutic transgene factors to autoimmune inflammatory lesions.

24 at lower doses, with development of chronic inflammatory lesions.

25 tissue localization, and their prominence in inflammatory lesions.

26 NFkappaB-mediated cytokine production in the inflammatory lesions.

27 or TNFRp55 in resolution of parasite-induced inflammatory lesions.

28 dy production as well as in the induction of inflammatory lesions.

29 expression of this gene within cells in the inflammatory lesions.

30 g CD11b+ monocyte/macrophage diapedesis into inflammatory lesions.

31 ant in development or maintenance of chronic inflammatory lesions.

32 nstituents of the tissue microenvironment of inflammatory lesions.

33 gical environments, such as solid tumors and inflammatory lesions.

34 was performed to look for active and chronic inflammatory lesions.

35 the CNS leading to a selective enrichment in inflammatory lesions.

36 er of cluster of differentiation 45-positive inflammatory lesions.

37 ulation of CD207(+) dendritic cells (DCs) in inflammatory lesions.

38 ided effector and memory T cell migration to inflammatory lesions.

39 acaques that demonstrated moderate to severe inflammatory lesions.

40 e as a neuroimaging method for assessment of inflammatory lesions.

41 enchymal origin in human cancers and chronic inflammatory lesions.

42 suitable marker for the in vivo detection of inflammatory lesions.

43 Elevated PGE(2) is a hallmark of most inflammatory lesions.

44 ction, with fewer neutrophils present in the inflammatory lesions.

45 in younger patients, particularly those with inflammatory lesions.

46 vel, noncytolytic infection, causing ongoing inflammatory lesions.

47 scular disease characterized by formation of inflammatory lesions.

48 essing cells as a dominant population within inflammatory lesions.

49 Of the 18 inflammatory lesions, 3 (17%) showed an increase and 15

50 Here, we report that in inflammatory lesions, a second barrier composed of react

51 cy in progressive multiple sclerosis without inflammatory lesion activity.

52 Homozygotes display chronic inflammatory lesions affecting the feet, salivary glands

53 ims of this study were to assess periodontal inflammatory lesions after P. gingivalis-induced periodo

54 n of dinitrofluorobenzene, and show enhanced inflammatory lesions after topical applications of phorb

55 These inflammatory lesions also exhibited evidence of axonal i

56 Active inflammatory lesions also exhibited staining for decorin

57 le of delivering high doses to periodontitis inflammatory lesion and cells) on experimental periodont

58 whether a few T cells arrive to initiate the inflammatory lesion and subsequently expand locally, or

59 '-(18)F-fluoromaltotriose is not taken up by inflammatory lesions and appears to be specific to bacte

60 RL/lpr) spontaneously develop lacrimal gland inflammatory lesions and are a model for the human disea

61 ormalities that indicate the distribution of inflammatory lesions and axonal loss (MRI); interference

62 14 weeks, tissue samples were evaluated for inflammatory lesions and cytokine messenger RNA by real-

63 ions revealed no significant differences for inflammatory lesions and demyelination, cytokine product

64 utoimmunity as exemplified by the multifocal inflammatory lesions and early demise of the TGF-beta1 n

65 MRI is capable of detecting more inflammatory lesions and erosions than US, X-ray, or CT.

66 NKG2D are highly expressed in carcinomas and inflammatory lesions and have been linked to immunosurve

67 the strains of parasites resulted in severe inflammatory lesions and high numbers of parasites in ey

68 tial restriction is imposed on the spread of inflammatory lesions and highlight systemic ACKR2 induct

69 t from cells, but is found at high levels in inflammatory lesions and in many premalignant and malign

70 TSG-6 protein, up-regulated in inflammatory lesions and in the ovary during ovulation,

71 alpha mice paralleled the development of the inflammatory lesions and included primary and secondary

72 lf may increase the influx of neutrophils in inflammatory lesions and influence disease susceptibilit

73 gnancies, whereas the uptake of (18)F-FDG in inflammatory lesions and normal breast tissues decreases

74 developed a chronic sustained disease, with inflammatory lesions and primary demyelination in the sp

75 ecificities of lymph node cells, and reduced inflammatory lesions and secreted IL-17 and IL-2 from pe

76 that Candida colonization delays healing of inflammatory lesions and that inflammation promotes colo

77 ifferentiate demyelinated lesions from other inflammatory lesions and therefore cannot predict diseas

78 to leukocytes and possibly microglia within inflammatory lesions and TIMP-1 expression that was obse

79 e autotoxic if overproduced, as evidenced in inflammatory lesions and tissue destruction in experimen

80 how that CD56(bright) NK cells accumulate in inflammatory lesions and, in the appropriate cytokine en

81 , increased overt loss of stratum corneum in inflammatory lesions, and impaired stratum corneum thick

82 that RRV- and CHIKV-induced musculoskeletal inflammatory lesions, and macrophages present in these l

83 ay predominate over Th2 lymphocytes in these inflammatory lesions, and that prevention of diabetes by

84 Granulomatous inflammatory lesions are a major histopathological featu

85 findings suggest that fibroproliferative and inflammatory lesions are independent entities, both of w

86 ane inflammatory lesions, but that placental inflammatory lesions are not associated with increased p

87 Because the inflammatory lesions are primarily orchestrated by Th1 c

88 The inflammatory lesions are primarily perpetuated by neutro

89 ating the poorly defined mechanisms by which inflammatory lesions are spatially restricted in vivo is

90 mice, but not Fas-deficient mice, maintained inflammatory lesions associated with either Leishmania m

91 was helpful in controlling the mucogingival inflammatory lesions associated with this condition.

92 erythematosus characterized by cold-induced inflammatory lesions at acral locations presenting in ea

93 ystemic and tissue-specific autoimmunity and inflammatory lesions at mucosal interfaces.

94 outcome that was based on assessment of new inflammatory lesions, best corrected visual acuity, ante

95 treatment is not solely derived from stromal inflammatory lesions but likely also originates from the

96 are at increased risk for placental membrane inflammatory lesions, but that placental inflammatory le

97 e infected for 365 d have very few organized inflammatory lesions, but the bacteria continue to persi

98 FTY720 has been used to control inflammatory lesions, but the mechanisms by which the dr

99 e disease activity index, decreasing colonic inflammatory lesions by 4-fold, and suppressing inflamma

100 ates specifically in tuberculosis-associated inflammatory lesions by selective retention within macro

101 te that some of the neutrophils recruited to inflammatory lesions can differentiate into neutrophil-D

102 tantial demyelination results from the focal inflammatory lesion caused by the injection of lipopolys

103 The SUV of inflammatory lesions caused by radiation therapy (+1.16%

104 objective was to compare the distribution of inflammatory lesions centrally and laterally within the

105 tient with metastatic melanoma who developed inflammatory lesions circumscribing pigmented areas of s

106 and more (3.1 vs 0.3, P = .008) subclinical inflammatory lesions compared with DTPA-Gd, including in

107 2-weighted images was seen in 12 of 14 (86%) inflammatory lesions compared with four of 21 (19%) HNF-

108 Atherosclerotic plaques are chronic inflammatory lesions composed of dysfunctional endotheli

109 IL-26 expressed in inflammatory lesions confers proinflammatory properties

110 tained numerous perivascular and parenchymal inflammatory lesions consisting of predominantly CD4+ an

111 In biopsies with active inflammatory lesions containing Langerhans' cells, hyper

112 cell histiocytosis (LCH) is characterized by inflammatory lesions containing pathologic CD207(+) dend

113 nd 9% (-16 to 38) in controls (p=0.023), and inflammatory lesion counts reduced by 49% (30 to 75) in

114 (+18% +/- 8%; P < 0.01), whereas the SUVs of inflammatory lesions decreased over time (-17% +/- 13% o

115 1c and MHC II expression when recovered from inflammatory lesions, demonstrating neutrophil --> hybri

116 ochemical demonstration of HHV-6 antigens in inflammatory lesions, detection of increased HHV-6 speci

117 Significant inflammatory lesions develop initially in the periductal

118 lved in the mechanism by which these chronic inflammatory lesions develop.

119 ture, but secreted TNF is needed for optimal inflammatory lesion development.

120 contrast in liver, spleen, lymph nodes, and inflammatory lesions (eg, atherosclerotic plaques).

121 l validated models that mimic aspects of the inflammatory lesion evident in diseases such as COPD.

122 ultinucleated giant cells from patients with inflammatory lesions expressed CD44V6- and CD44V9-contai

123 Multifocal inflammatory lesions featuring destruction of lipid-rich

124 cells increased disease activity and colonic inflammatory lesions following C. difficile infection.

125 late BBB permeability changes and autoimmune inflammatory lesion formation within the brain elicited

126 Rapamycin treatment reduced inflammatory lesions formed in the ears of Leishmania-in

127 ly sensitive and specific in differentiating inflammatory lesions from malignant lesions.

128 e and attract T cells and eosinophils to the inflammatory lesion has not been determined.

129 d spatial relationship between HSV-1 DNA and inflammatory lesions has been previously reported for th

130 After induction of a focal inflammatory lesion in the brain, there is rapid hepatic

131 in the serum following generation of a focal inflammatory lesion in the brain.

132 ection with herpes simplex virus leads to an inflammatory lesion in the cornea orchestrated by CD4+ T

133 on with HSV causes a chronic T cell-mediated inflammatory lesion in the cornea.

134 Early SD OCT revealed an inflammatory lesion in the photoreceptor outer segment l

135 nition of a similar self antigen provokes an inflammatory lesion in the target organ.

136 MRI ruled out the presence of active inflammatory lesions in 60.4% of patients with sacroilii

137 that CD56(bright) NK cells accumulate within inflammatory lesions in a wide variety of clinical disea

138 te to glomerular macrophage infiltration and inflammatory lesions in aging.

139 In contrast, inflammatory lesions in B10.D2 recipients were reminisce

140 ce correlate with spontaneous development of inflammatory lesions in different organs of aged Sin(-/-

141 With MRI, we were able to detect inflammatory lesions in diseased rats, which correlated

142 essary step in the development of pathologic inflammatory lesions in experimental autoimmune encephal

143 ocess, but predispose patients to developing inflammatory lesions in extraarticular tissues.

144 venules (high endothelial venules [HEVs]) in inflammatory lesions in Helicobacter species-infected li

145 nd confirm more, smaller, and earlier active inflammatory lesions in living mice by in vivo MRI.

146 on may facilitate the development of chronic inflammatory lesions in Lyme disease.

147 ious inflammatory stimuli and a reduction of inflammatory lesions in models of demyelinating disease.

148 utoimmune renal, vasculitic, and intraocular inflammatory lesions in MRL/lpr mice.

149 d-brain barrier (BBB) is a hallmark of acute inflammatory lesions in multiple sclerosis (MS) and its

150 be a second step during the formation of new inflammatory lesions in multiple sclerosis.

151 ic gastrointestinal inflammation, as well as inflammatory lesions in other tissues.

152 The assembly of inflammatory lesions in rheumatoid arthritis is highly r

153 ltrating mononuclear cells into CNS, minimal inflammatory lesions in spinal cord, and preservation of

154 doscopies and was found out to have multiple inflammatory lesions in the area extending from the cecu

155 e macrophages and microglia were detected in inflammatory lesions in the brain of children with sever

156 drocytes are exposed to various cytokines in inflammatory lesions in the central nervous system.

157 OX-40R+ T cells isolated from inflammatory lesions in the CNS of animals with experime

158 ression is induced in astrocytes surrounding inflammatory lesions in the CNS.

159 ppressed clinical signs of EAE and abolished inflammatory lesions in the CNS.

160 roptosis, Paneth cell loss and focal erosive inflammatory lesions in the colon.

161 istence of HSV-1 DNA and its relationship to inflammatory lesions in the conjunctiva and eyelid skin

162 S from MOG-immunized mice revealed extensive inflammatory lesions in the cPLA2alpha+/- mice, whereas

163 Spinal cord inflammatory lesions in the EAE model can be noninvasive

164 skin patches and alleviated pneumonitis and inflammatory lesions in the extremities of me/me mice co

165 o most mouse models of mucosal inflammation, inflammatory lesions in the gastrointestinal tract of Si

166 aR(-/-)) mice uniformly develop angiocentric inflammatory lesions in the lung.

167 but noninvasively, visualize the lymphocytic/inflammatory lesions in the pancreatic islets.

168 Therefore, in order to avoid missing inflammatory lesions in the paranasal sinuses, it is rea

169 ecruitment of circulating cells into chronic inflammatory lesions in the skin and elsewhere.

170 ical subunit of LUBAC, spontaneously develop inflammatory lesions in the skin and other organs.

171 ve distribution of meningeal and parenchymal inflammatory lesions in the spinal cord and optic nerves

172 n of mice develops discontinuous, transmural inflammatory lesions in the terminal ileum with 100% pen

173 YitFc mice develop discontinuous, transmural inflammatory lesions in the terminal ileum, similar to w

174 at induce histologically distinct autoimmune inflammatory lesions in the thyroid.

175 load caused elevated levels of apoptosis and inflammatory lesions in these mice and produced a smalle

176 Thus, it appears plausible that the inflammatory lesions in top3beta(-/-) mice are caused by

177 Inflammatory lesions in VEGF-A transgenic mice closely r

178 regulate chemokine secretion by monocytes in inflammatory lesions in vivo and provide a model for the

179 permitting noninvasive visualization of the inflammatory lesions in vivo in real time.

180 lymph node T cells from Tg mice, and caused inflammatory lesions in white matter of the CNS and symp

181 Radiographs do not allow early inflammatory lesions indicating sacroiliitis to be diagn

182 resulting in localized tissue hypoxia within inflammatory lesions ("inflammatory hypoxia").

183 The elimination of lymphocytes within inflammatory lesions is a critical component in the reso

184 Although development of multifocal inflammatory lesions is the underlying pathological proc

185 channel 1 expression in neurons and glia in inflammatory lesions is unknown and, crucially, acid-sen

186 rosis (MS) is an autoimmune disease in which inflammatory lesions lead to tissue injury in the brain

187 e detected in histologically normal skin and inflammatory lesions (lichen sclerosus), chromosomal abn

188 Resection of the inflammatory lesion may be curative.

189 At the LM level, the inflammatory lesion of peri-implantitis was in most case

190 ic factors do not permit the evolution of an inflammatory lesion of sufficient magnitude to induce ov

191 tis of unknown etiology (VUE), a destructive inflammatory lesion of villous placenta, is characterize

192 ctin function to recruit leukocytes into the inflammatory lesions of diseases such as rheumatoid arth

193 ion of interleukin 10 by glial cells in both inflammatory lesions of EAE and normal-appearing CNS whi

194 Fewer apoptotic cells were detected in inflammatory lesions of lpr mice than in wild-type lesio

195 y astrocytes and infiltrating macrophages in inflammatory lesions of MS patients.

196 polymorphisms on periodontal parameters and inflammatory lesions of oral mucosa as a characteristic

197 Inflammatory lesions of periodontal disease contain all

198 TSP2 has regulatory function in the chronic inflammatory lesions of rheumatoid arthritis.

199 Inflammatory lesions of target organs are characterized

200 ASIC1 contributes to axonal degeneration in inflammatory lesions of the central nervous system (CNS)

201 isite cell population for the genesis of the inflammatory lesions of the islets of Langerhans.

202 Because telomerase activity can be found in inflammatory lesions of the skin, this indicates that te

203 quired to induce apoptosis of T cells within inflammatory lesions once pathogens are eliminated, and

204 nder the acidotic tissue conditions found in inflammatory lesions opens to allow influx of sodium and

205 coxibs are ideal candidates for detection of inflammatory lesions or early-stage COX-2-expressing hum

206 47 +/- 0.09, compared with 0.73 +/- 0.18 for inflammatory lesions (P = .0004), 0.82 for the beta-cate

207 k4a and p19/Arf in CNT- and asbestos-induced inflammatory lesions precedes mesothelioma; this results

208 However, inflammatory lesions, predominantly lymphocytic, develop

209 l/macrophage activation at the site of focal inflammatory lesions, presumably by preventing leukocyte

210 P) are cleared from sites of inflammation as inflammatory lesions resolve.

211 degeneration specifically at the site of the inflammatory lesions, suggesting that locally produced i

212 are also associated with the pathogenesis of inflammatory lesions, suggesting that the modulation of

213 inducer, and iNOS, before the appearance of inflammatory lesions, suggests that failed regulation of

214 gPL1 are more resistant to TE and have fewer inflammatory lesions than mice infected with the wild ty

215 ue with a CD4(+) T-cell-orchestrated chronic inflammatory lesion that impairs vision.

216 ain viable in microenvironments of immune or inflammatory lesions that are rich in cytotoxic inflamma

217 Disease exacerbation with more extensive inflammatory lesions that contained activated cells of t

218 Chronic inflammatory lesions that developed in the kidney and pa

219 elapsing-remitting clinical course and focal inflammatory lesions that have a predilection for the pe

220 estinal helicobacter species develop hepatic inflammatory lesions that have previously been described

221 ing modality for the assessment intensity of inflammatory lesions.The aim of this study was to measur

222 It is postulated that IL-13 drives inflammatory lesions through the modulation of both hema

223 te-stage syphilis can lead to development of inflammatory lesions throughout the body, which can lead

224 the tetracycline-based MMP inhibitor in the inflammatory lesion, thus synergistically enhancing the

225 e that proceeds from initial peribronchiolar inflammatory lesions to characteristic, fibrotic cellula

226 ing our ability to diagnose malignancies and inflammatory lesions, to grade severity of pancreatitis,

227 In giant cell arteritis (GCA), inflammatory lesions typically produce interferon-gamma(

228 lows for defining localization and extent of inflammatory lesions, visualizes soft tissue involvement

229 Spinal cord inflammatory lesions were also reduced in Panx1 KO EAE m

230 , the prevalence and severity of multisystem inflammatory lesions were comparable in backcross rats b

231 ues 3 days after virus challenge, and severe inflammatory lesions were found in the spleen and liver

232 the two groups of mice, distinct patterns of inflammatory lesions were found in their livers at 7-14

233 Inflammatory lesions were more diffuse and extensive in

234 No inflammatory lesions were observed in the ileum or colon

235 one of the sinuses.Measurements of the same inflammatory lesions were performed sequentially with di

236 otype, infiltrates of MS2-3C8 Tg T cells and inflammatory lesions were predominantly located in the b

237 In Trial 2, inflammatory lesions were significantly reduced at 12 we

238 coccus or group G streptococcus developed an inflammatory lesion with high bacterial counts, marked n

239 oimmune syndrome characterized by multiorgan inflammatory lesions with a marked female predominance,

240 At 38 weeks, RFC1(+/-) mice developed local inflammatory lesions with or without epithelial dysplasi

241 The disease is characterized by focal inflammatory lesions with perifollicular T-cell infiltra

242 monstrated that patients with characteristic inflammatory lesions within the brain on magnetic resona

243 gh little is known about the distribution of inflammatory lesions within the structures of the spine.

244 f therapy, our patient had resolution of his inflammatory lesions without serious infections or adver