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1 decreased as a result of treatment with each inflammatory mediator.
2 h neonatal production of IL-1beta, an innate inflammatory mediator.
3 < 0.001-0.001) were increased in response to inflammatory mediators.
4 s (SGs) and the release of many allergic and inflammatory mediators.
5 t increases gene expression of catabolic and inflammatory mediators.
6 nsaturated FAs, which are precursors of anti-inflammatory mediators.
7 ts that lead to degranulation and release of inflammatory mediators.
8 ith complement consumption and production of inflammatory mediators.
9 ption of kinase signaling and degradation of inflammatory mediators.
10 crosstalk exists between these 2 classes of inflammatory mediators.
11 lted in enhanced signaling and expression of inflammatory mediators.
12 and whether HCV clearance normalizes soluble inflammatory mediators.
13 n signature genes" that encode antiviral and inflammatory mediators.
14 antly alleviated post-ischemic expression of inflammatory mediators.
15 s a critical regulatory node in a network of inflammatory mediators.
16 gers that regulate the expression of various inflammatory mediators.
17 nflammasome-driven maturation into bioactive inflammatory mediators.
18 induction of autophagy and the regulation of inflammatory mediators.
19 s a critical role in the induction of innate inflammatory mediators.
20 in part, by influencing multiple downstream inflammatory mediators.
21 nced mRNA degradation and underexpression of inflammatory mediators.
22 ctor and inhibitor of the expression of many inflammatory mediators.
23 tream of BAFF, CD40L, lymphotoxin, and other inflammatory mediators.
24 actor (VWF) and a cocktail of angiogenic and inflammatory mediators.
25 ociated fibroblasts, T regulatory cells, and inflammatory mediators.
26 ished basal and stress-induced levels of pro-inflammatory mediators.
27 neural activity and not by release of local inflammatory mediators.
28 bioactive molecules including pro- and anti-inflammatory mediators.
29 rogated the disruption of AJs in response to inflammatory mediators.
30 to suggest dynamic connectivity and central inflammatory mediators.
31 gent currents in DRG neurons are enhanced by inflammatory mediators.
32 y respond to allergen challenge by releasing inflammatory mediators.
33 negatively affected by the up-regulation of inflammatory mediators.
34 inflammatory monocyte subsets and release of inflammatory mediators.
35 e in differentiating NSC cultures exposed to inflammatory mediators.
36 e unexpectedly primed to respond robustly to inflammatory mediators.
37 eneous at the biological level of individual inflammatory mediators.
38 sion and instead secreted IL6 and additional inflammatory mediators.
39 rf2 targets, cytokines, chemokines and other inflammatory mediators.
40 tivating NF-kappaB and induced expression of inflammatory mediators.
41 loperoxidase (MPO) and the expression of pro-inflammatory mediators.
42 xpression of tumor necrosis factor and other inflammatory mediators.
47 LGP2 TG mice displayed significantly reduced inflammatory mediators and a lower leukocyte infiltratio
48 admission and over time were assayed for 26 inflammatory mediators and analyzed for the presence of
49 r engagement by phagosomal cargo, as well as inflammatory mediators and cellular activation affect ma
52 repair, such that uncontrolled production of inflammatory mediators and growth factors, deficient gen
53 cient mice exhibited increased expression of inflammatory mediators and increased immune cell recruit
54 t includes enhanced production of endogenous inflammatory mediators and increased synthesis of matrix
55 cell-bound IgE, resulting in the release of inflammatory mediators and initiation of the allergic ca
56 Notch was induced on naive CD8(+) T cells by inflammatory mediators and interleukin 2 (IL-2) via path
59 bstention and in the correlation of specific inflammatory mediators and microbial taxa with clinical
60 ed by the combined action of disturbed flow, inflammatory mediators and oxidants derived from cigaret
62 n and histopathology, reduces intrarenal pro-inflammatory mediators and salvages kidney function long
63 o small changes in sodium concentration with inflammatory mediators and suggest that the ENaC pathway
64 state characterized by elevated secretion of inflammatory mediators and that this effect could be blu
65 immune responses, we describe the cascade of inflammatory mediators and the implications of their pos
68 ocess associated with a dramatic increase in inflammatory mediators and tissue-resident immune cells.
69 cided with the decrease of viral-induced pro-inflammatory mediators and viral-induced nuclear translo
70 TIV immunization was associated with potent inflammatory mediators and virus-specific CD8 T cell act
71 The clusters differed in concentrations of inflammatory mediators, and cluster membership was influ
72 morphology, exhibited limited production of inflammatory mediators, and failed to induce robust T ce
73 NF-kappaB activity, glomerular expression of inflammatory mediators, and glomerular recruitment and r
74 ced elevated complement, leukocyte CD11b and inflammatory mediators, and in Wistar rats increased fib
75 eukin-1beta (IL-1beta) is one of the key pro-inflammatory mediators, and its maturation is tightly co
76 ed similar responses in clinical parameters, inflammatory mediators, and proportions of individual mi
77 rease in number, release increased levels of inflammatory mediators, and respond poorly to glucocorti
79 metabolic disorder by modulating macrophage inflammatory mediators, and that this effect is associat
82 ndrin-expressing mice, suggesting that these inflammatory mediators are less active in the airways in
85 trated increased skin expression of the anti-inflammatory mediator arginase-1 (P = 0.005), and a sust
86 basophil-bound IgE and immediate release of inflammatory mediators, as well as late-phase and chroni
88 s systemically via circulating metabolic and inflammatory mediators associated with adipose inflammat
89 reatment also reduced gingival production of inflammatory mediators augmented in LPS-injected rats, s
90 ce of this shedding can be the production of inflammatory mediators, because treatment of astrocytes
92 nally, combined application of TLC-S and the inflammatory mediator bradykinin caused more extensive n
93 ated that anaphylatoxins not only act as pro-inflammatory mediators but as immunoregulatory molecules
94 26 down-regulation enhanced secretion of pro-inflammatory mediators by 3T3-L1 adipocytes as well as i
95 ipal mechanisms behind the overexpression of inflammatory mediators by Dusp1(-/-) cells are not known
96 ed by PgLPS, and monitored for production of inflammatory mediators by enzyme-linked immunosorbent as
98 n, TLR4 activation elicited secretion of pro-inflammatory mediators by MSCs, whereas TLR3-activated M
100 hich is believed to be driven by gut-derived inflammatory mediators carried via mesenteric lymph (ML)
101 s states that an excessive production of pro-inflammatory mediators causes early deaths, whereas a pr
102 reduces the expression of mTOR and other pro-inflammatory mediators, consequently slowing down muscle
103 IV infection, it is not clear how or whether inflammatory mediators contribute to immune restoration
106 tem and in the production of chemotactic and inflammatory mediators, creating a condition that can be
107 downstream transcriptional gene targets, the inflammatory mediator cyclooxygenase 2, and the matricel
109 udin, and JAM-A; however, exposure of SCs to inflammatory mediators derived from ZIKV-infected macrop
110 Sertoli cell barrier to describe how ZIKV or inflammatory mediators derived from ZIKV-infected macrop
111 associated with death, the balance of these inflammatory mediators does not seem to impact either ea
112 NOS, peroxynitrite (ONOO(-)) is a well-known inflammatory mediator during a number of physiological a
113 strong evidence that versican is a critical inflammatory mediator during poly(I:C)-induced acute lun
114 lammation by inducing the production of anti-inflammatory mediators during the phagocytosis of apopto
116 lonality, correlated with mRNA levels of key inflammatory mediators (e.g., IL-13, CCL17, IL23p19, CXC
117 these events contribute to the production of inflammatory mediators, either together or separately.
119 core coated with siRNA directed against pro-inflammatory mediators, encapsulated into poly(d,l-lacti
120 Cigarette smoke constituents and systemic inflammatory mediators enhance proteolysis and inhibit p
121 ession of IL-17-induced keratinocyte-derived inflammatory mediators, epidermal hyperproliferation, an
123 sminogen activator, attenuated expression of inflammatory mediators, even in the presence of LPS.
124 afferents by pathology in the airways (e.g., inflammatory mediators, excessive mucus) or an altered n
125 had the entirely opposite effect, promoting inflammatory mediator expression and mimicking LRP1 dele
126 observed cigarette smoke to attenuate nasal inflammatory mediator expression, particularly that of n
128 response, is a constituent of the eicosanoid inflammatory mediator family of molecules that promote b
129 y contribute to PAH vasculopathy by enabling inflammatory mediator flux across the endothelial barrie
131 annels induces the production of several key inflammatory mediators from AECs including thymic stroma
132 oy receptor significantly reduced release of inflammatory mediators from Muller cells, inhibited accu
134 r composition (osmolarity, lacrimal factors, inflammatory mediators, growth and differentiation facto
137 cal trials that have attempted to antagonize inflammatory mediators have been negative with respect t
139 d kinase-1, leading to induction of the anti-inflammatory mediators IDO, IL-10, and PGE2 in a COX-2-d
140 e mitochondrial membrane by sPLA2-IIA yields inflammatory mediators (ie, lysophospholipids, fatty aci
141 atory markers accumulated, and expression of inflammatory mediators IFN-gamma and TNF-alpha was reduc
142 ty is mobilized in Treg cells in response to inflammatory mediator IL-18 or alarmin IL-33, but not by
143 and IL-8) while inducing the release of anti-inflammatory mediators (IL-10 and IL-1 receptor antagoni
145 timulating factor (GM-CSF or Csf-2) is a pro-inflammatory mediator implicated in the pathogenesis of
146 ls have traditionally been recognized as pro-inflammatory mediators implicated in a myriad of disease
147 ase is central to the regulation of multiple inflammatory mediators implicated in acute organ dysfunc
148 PBMCs attenuated the expression of numerous inflammatory mediators implicated in the TSS-associated
149 Upon infection, the immune system produces inflammatory mediators important for pathogen clearance.
150 or Wnt5a in macrophage recruitment and as an inflammatory mediator in human dental pulp inflammation.
151 We suggest that IKKepsilon may be a key inflammatory mediator in the hypothalamus of obese mice,
152 that resveratrol decreases expression of pro-inflammatory mediators in airway epithelial cells and in
155 ted microRNAs altered expression of selected inflammatory mediators in cell culture gain-of-function
157 1 signaling contributes to overexpression of inflammatory mediators in CML LSC, suggesting that block
158 hat prenatal exposures, reflected by soluble inflammatory mediators in cord blood, can condition an i
159 This study aimed to characterise systemic inflammatory mediators in established DLB and AD, as wel
160 uce periodontal probing depth (PD) and local inflammatory mediators in gingival crevicular fluid (GCF
161 t of liver fibrosis, focusing on the role of inflammatory mediators in hepatic stellate cell (HSC) ac
162 15-LOX products and reduce production of pro-inflammatory mediators in human whole blood assays.
163 dial infarct size and elevated expression of inflammatory mediators in ischemic heart following ische
166 Our data indicate a key role for allergic inflammatory mediators in modulating nasal epithelial ba
167 studies have demonstrated the time course of inflammatory mediators in nasal fluids following nasal a
170 We observed that islets release multiple inflammatory mediators in patients undergoing islet tran
171 e chemokine CCL2 is one of the most elevated inflammatory mediators in patients with pharmacoresisten
173 lenge leads to the production and release of inflammatory mediators in the brain in association with
175 2- to 3-fold increased expression levels of inflammatory mediators in the liver and kidney, compared
176 trols the expression of a specific subset of inflammatory mediators in the mouse epidermis, which tri
178 une cell subsets and nonclassical Th2-biased inflammatory mediators in the tumour microenvironment ca
179 xamine here the expression of vasoactive and inflammatory mediators in the vitreous of patients with
180 ically distinct, regulation of pro- and anti-inflammatory mediators in TR APOE4/4 murine microglia th
181 ore sought to convert endogenous IgG to anti-inflammatory mediators in vivo by engineering solubilize
182 as well as the mRNA expression of other pro-inflammatory mediators, in human and mouse chondrocytes.
185 efined by exaggerated bronchoconstriction to inflammatory mediators including acetylcholine (ACh), br
186 sponses is due to the aberrant production of inflammatory mediators including C-X-C motif chemokine l
187 imulation induces the production of many key inflammatory mediators including PGE2, IL-6, IL-8, and G
188 mice showed increased mRNA levels of several inflammatory mediators, including Ccl2, Ccl5, Ccl7, Cox-
189 pacts the production of important antifungal inflammatory mediators, including IL-1beta, IL-6, KC, an
191 arked production of diverse nonclassical TH2 inflammatory mediators, including IL-22, IL-8, and GM-CS
192 Tet2 resulted in the upregulation of several inflammatory mediators, including IL-6, at late phase du
194 ic in the post-TKA joint, expresses multiple inflammatory mediators, including the monocyte chemoattr
195 lococcus aureus, as well as the secretion of inflammatory mediators, including TNF-alpha, IL-6, and I
196 mucosal surfaces and are a potent source of inflammatory mediators, including tumor necrosis factors
200 e and on the gingival crevicular fluid (GCF) inflammatory mediator interleukin-1beta (IL-1beta) in pa
201 tively correlated with ex vivo production of inflammatory mediators interleukin-6, tumor necrosis fac
202 ffects of pemphigus autoantibodies and other inflammatory mediators into perspective and broaden our
203 rcumstances the cross-talk between these key inflammatory mediators is a particular requirement for e
204 hat promote release of mast cell-derived pro-inflammatory mediators is necessary to dampen activation
207 kotriene A4, the precursor to the potent pro-inflammatory mediators leukotriene B4 and leukotriene C4
209 tion, the mast cell-derived vasodilatory and inflammatory mediators may contribute markedly to the co
211 infiltration and activation, and release of inflammatory mediators-mostly in the colon, then in the
212 TNFalpha is a known activator of the central inflammatory mediator NF-kappaB, and can induce the intr
213 CD73(-/-) mice produced higher levels of the inflammatory mediators nitric oxide, tumor necrosis fact
214 apacity, human DC matured in the presence of inflammatory mediators of type 1 immunity are uniquely p
215 effect of urgently needed more specific anti-inflammatory mediators on mucosal and skin lesions in au
218 has no effect on the hyperalgesia induced by inflammatory mediators or paclitaxel, it eliminates the
219 Consistent with the activation of these inflammatory mediators, OT led to increases in the expre
220 ensitivity of nociceptors in the presence of inflammatory mediators, our finding that continuing cAMP
222 disease, with neutrophil expression of anti-inflammatory mediators peaking during early-stage and mi
224 ationic Protein and histamine, two important inflammatory mediators previously described in the perio
225 in nephrotoxicity and raise the concern that inflammatory mediators produced by renal parenchymal cel
226 y inhibited bacteria-induced profibrotic and inflammatory mediator production by peritoneal leukocyte
227 entified the mechanism whereby RvD1 disrupts inflammatory mediator production induced by the viral mi
228 al role of Adam10 for leukocyte recruitment, inflammatory mediator production, and extracellular matr
232 neurons exhibited TrpV1 sensitization to the inflammatory mediator prostaglandin E2 and the chemother
233 chronic, the ongoing release of multiple pro-inflammatory mediators, proteases, cytokines and chemoki
234 urinary bladder signalling mechanisms and an inflammatory mediator provides novel insight into bladde
235 ts dietary fiber, by reducing the release of inflammatory mediators, providing the basis for SCG use
236 mucosal tissues, sensing release of soluble inflammatory mediators, rapidly communicating danger via
237 olonization and provide new insight into the inflammatory mediators regulating host-pathogen interact
238 TS: Chronic limb ischaemia, characterized by inflammatory mediator release and a low extracellular pH
239 of these cytokines can initiate a cascade of inflammatory mediator release that can lead to wholesale
242 skin barrier function and overexpression of inflammatory mediators released by the skin affected by
244 s imbalance was associated with an increased inflammatory mediator response and more lung injury (wet
247 creased metabolic activity and an attenuated inflammatory mediator secretion were found in response t
249 il products, and also implicate phospholipid inflammatory mediators, specific transcription factors a
255 notransferase and lactate dehydrogenase, and inflammatory mediators such as monocyte chemoattractant
256 ioxidant treatment blunted the expression of inflammatory mediators such as PAI-1 (plasminogen activa
260 f TTP caused excessive protein production of inflammatory mediators, suggesting TTP-dependent transla
261 e results establish a causal link between an inflammatory mediator, TGF-beta, and intrinsic signallin
262 L functioning as an endocrine and local anti-inflammatory mediator that antagonizes pro-inflammatory
264 activated fetal lung macrophages is the key inflammatory mediator that disrupts airway morphogenesis
266 (Tpl2, also known as Map3k8/Cot) is a potent inflammatory mediator that drives the production of TNFa
267 his model system, IL1beta acted as intrinsic inflammatory mediator that exerted an autocrine influenc
268 lammation we utilized TNFalpha, a potent pro-inflammatory mediator that is elevated in the serum and
270 eukocyte-epithelial interactions, as well as inflammatory mediators that affect the epithelial barrie
271 cle, we demonstrate that CCL2 and TNF-alpha, inflammatory mediators that are elevated in the CNS of H
272 ound IgE antibody, and triggers secretion of inflammatory mediators that contribute to allergic react
273 al factors and tumor suppressors, as well as inflammatory mediators that demarcate the secretome of s
274 cture in mycobacterial infection, as well as inflammatory mediators that drive a successful anti-micr
277 n have opposing effects on the generation of inflammatory mediators that underpin the pathogenesis of
278 t target autoreactive T and B cells and anti-inflammatory mediators, that is, dimethyl fumarate, phos
279 ulates apoptotic responses and production of inflammatory mediators, thereby contributing to therapy
280 tes and rat tibia explants with IL-1beta, an inflammatory mediator thought to participate in OA patho
281 ation of TRX-1 and enhanced transcription of inflammatory mediators through nuclear-factor-(NF)-kappa
282 s through TLRs, leading to the production of inflammatory mediators, TNF-alpha and leukotriene B4 (LT
283 significantly reduced the expression of pro-inflammatory mediators, TNF-alpha, IL-1 beta, IL-6, MMP-
285 proteases triggers the release of a host of inflammatory mediators to regulate bronchomotor tone and
286 pattern recognition receptors, receptors for inflammatory mediators, transcription factors including
287 xtracellular PRDX2 acts as a redox-dependent inflammatory mediator, triggering macrophages to produce
288 orders by rapid degranulation and release of inflammatory mediators upon antigen-driven engagement of
289 days 1 to 7 postinjury) were assessed for 24 inflammatory mediators using Luminex, and No2-/No3- was
290 inflammasome-associated cytokines and other inflammatory mediators was largely intact in Aim2-defici
291 h the mortality pattern, early production of inflammatory mediators was markedly enhanced in betaArr1
292 ukocyte migration, exudation levels and many inflammatory mediators, was therefore evaluated in an in
293 Tissue oxygenation (StO2), biochemical and inflammatory mediators were measured, and clinical outco
294 erated with low letrozole concentrations and inflammatory mediators were sufficient to provoke AIMSS-
295 immune response characterised by release of inflammatory mediators, which contribute to disease prog
296 eukocyte trafficking and blunt production of inflammatory mediators, while also promoting clearance o
297 genes and thus may represent a new group of inflammatory mediators with a potential pathogenic role
298 ads to accumulation of lactic acid and other inflammatory mediators with a subsequent drop in interst
299 eta and stimulates the expression of various inflammatory mediators with negative myocardial inotropi
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