ライフサイエンスコーパス: inflammatory response

1 inflammation in order to maintain a balanced inflammatory response.

2 promising control of bacteria that drive the inflammatory response.

3 (HLH) both clinically and based on molecular inflammatory response.

4 terferon-alpha response and an overall acute inflammatory response.

5 eration depends on a robust albeit transient inflammatory response.

6 ight therefore be expected to induce a local inflammatory response.

7 uction of the acute arterial WSS-induced pro-inflammatory response.

8 hat the virus follows, it causes significant inflammatory response.

9 rigeminovascular system, evoking a meningeal inflammatory response.

10 what is known about the role of urate in the inflammatory response.

11 ematological system development/function and inflammatory response.

12 reperfusion reduced the systemic and cardiac inflammatory response.

13 (ECs) lining the blood vessels regulates the inflammatory response.

14 istently revealed a unique and inappropriate inflammatory response.

15 kines that categorically incite a robust pro-inflammatory response.

16 ory protein (cFLIP) in the regulation of the inflammatory response.

17 microenvironment of the initial post-injury inflammatory response.

18 ial cytotoxicity that can often accompany an inflammatory response.

19 attenuates NF-kappaB activation and reduces inflammatory response.

20 ion plays a critical role in controlling the inflammatory response.

21 essential role of this pathway in macrophage inflammatory response.

22 pyelonephritis, which are associated with an inflammatory response.

23 t radiograph experience a more intense early inflammatory response.

24 roptotic cell death, or may be related to an inflammatory response.

25 associated with a significant acute systemic inflammatory response.

26 ochondrial health in addition to a decreased inflammatory response.

27 ed to cellular proliferation, apoptosis, and inflammatory response.

28 nfarction (MI) triggers a local and systemic inflammatory response.

29 ovulation may be responsible for a localized inflammatory response.

30 on injury is associated with coagulation and inflammatory responses.

31 signaling changes; (iv) Oxidative stress and inflammatory responses.

32 ways may play an important role in promoting inflammatory responses.

33 omotes dendritic cell-mediated, age-specific inflammatory responses.

34 by the pituitary gland, regulates immune and inflammatory responses.

35 ading and enhanced secretion during cellular inflammatory responses.

36 terial activities and consequently increased inflammatory responses.

37 activate this pathway and trigger extensive inflammatory responses.

38 2-12(S)-HETE-lysophospholipids in mediating inflammatory responses.

39 e regulatory pathways to attenuate excessive inflammatory responses.

40 LS as a disorder with extensive systemic pro-inflammatory responses.

41 ated eosinophils in development and allergic inflammatory responses.

42 athogenic or physiologic stimuli to initiate inflammatory responses.

43 macrophages and endothelial cells to measure inflammatory responses.

44 L-18 acted on T lymphocytes to amplify their inflammatory responses.

45 1alpha positively regulates S aureus-induced inflammatory responses.

46 xacerbated acute tubular injury and enhanced inflammatory responses.

47 ro, this inhibitor blocks TLR signalling and inflammatory responses.

48 se of epidermal differentiation and enhanced inflammatory responses.

49 (PPARgamma), a nuclear receptor involved in inflammatory responses.

50 pe and improves resolution during pathologic inflammatory responses.

51 gluconeogenesis, and upregulated the hepatic inflammatory responses.

52 nvergent paradigm for fine-tuning macrophage inflammatory responses.

53 rated a role for FADD-caspase-8 in promoting inflammatory responses(7-12), but the mechanisms that un

54 iously demonstrated that the Salmonella anti-inflammatory response activator SarA (Stm2585, GogC, Pag

55 age-associated molecular pattern to activate inflammatory responses, activities that contribute to wo

56 ymphocytes may have an important role in the inflammatory response after aneurysmal rupture and were

57 hages orchestrate a strong, but ineffective, inflammatory response against uropathogenic, E. coli-ind

58 When compromised, activation of immune/inflammatory responses against exogenous allergens, micr

59 ds and various noxious cues by initiating an inflammatory response aimed at eliminating the original

60 Both treatments modulate inflammatory responses, albeit via different effector pa

61 rs of neuronal excitability, metabolism, and inflammatory responses, all of which were unpredictable

62 among participants with the most robust anti-inflammatory response, an effect corroborated in formal

63 hymol partially and positively modulated the inflammatory response and avoided H/L ratio alteration i

64 and the mechanism of alpha-hemolysin induced inflammatory response and cell death.

65 n-coding RNAs which are reported to regulate inflammatory response and cell proliferation.

66 anscriptional dysregulation indicative of an inflammatory response and cellular function deficits.

67 r, plasma biomarkers linked to inflammation (inflammatory response and endothelial dysfunction) were

68 ggest that APOE epsilon4 mediates an altered inflammatory response and increased tau pathology indepe

69 se parents were exposed to CHS showed higher inflammatory response and lower antibody production.

70 -treated myocardium and a suppression of the inflammatory response and mitogen-activated protein kina

71 The inflammatory response and mucin production were assessed

72 2019 (COVID-19) symptoms, including systemic inflammatory response and multisystem organ failure, are

73 tage, greater nutritional risk, the systemic inflammatory response and poorer survival but not body c

74 initially found that RGFP966 alleviated the inflammatory response and protected against ischemic str

75 atelet CLEC-2 influences the hepatic sterile inflammatory response and that this can be manipulated f

76 infarct to identify the drivers of the acute inflammatory response and the underlying signaling pathw

77 n inflammatory diseases dampens pathological inflammatory responses and can restore tissue homeostasi

78 fied recombinant alpha-hemolysin in inducing inflammatory responses and cell death in macrophages.

79 receptors is a conserved mechanism mediating inflammatory responses and cell fate decisions in variou

80 of hospitalized musculoskeletal trauma, the inflammatory responses and cell population dynamics that

81 RT7 deficiency promotes EndoMT with impaired inflammatory responses and dysfunction of the lung vascu

82 epletion on lipopolysaccharide (LPS)-induced inflammatory responses and endothelial barrier permeabil

83 estration in organs and consequent excessive inflammatory responses and endothelial damage.

84 tease-activated receptor-1 (PAR1) to promote inflammatory responses and endothelial dysfunction.

85 overexpressed 3T3-L1 cells, showed increased inflammatory responses and gluconeogenesis.

86 ow; and regulate permeability, angiogenesis, inflammatory responses and homeostatic tissue maintenanc

87 d transcriptome profiling identified several inflammatory responses and immune response signaling pat

88 covery depends on a delicate balance between inflammatory responses and immune suppression, tipping t

89 radiation exposure causes local and systemic inflammatory responses and induces cell and tissue damag

90 n-3 (omega-3) PUFAs modulate inflammatory responses and may help to prevent a proinfl

91 ms of neutrophil death typically elicit anti-inflammatory responses and promote healing, pathways end

92 nes regulating proliferation, migration, and inflammatory responses and significantly higher migratio

93 me key elements of the host immune response, inflammatory response, and blood coagulation.

94 ed to inflammation (bacterial translocation, inflammatory response, and endothelial dysfunction), coa

95 s were mainly associated with cell adhesion, inflammatory response, and extracellular exosome.

96 elated to the regulation of immune response, inflammatory response, and hypoxia (like TIMP1, HIF1A, S

97 the cerebral cortex, consistent with a post-inflammatory response, and that this reduction would be

98 entral to its ability to manipulate the host inflammatory response, and they demonstrate the integral

99 ellular processes, such as oxidative stress, inflammatory responses, and apoptosis, that are activate

100 Sterile stimuli can trigger inflammatory responses, and in some cases can lead to a

101 rmore, the printed construct elicits minimal inflammatory responses, and is shown to be efficiently b

102 roteins that may be linked to an increase in inflammatory response, apoptosis, glycolytic process and

103 These inflammatory responses are potentially counteracted by a

104 etal muscle radiodensity (SMD), the systemic inflammatory response as measured by the modified Glasgo

105 ation did not induce T(H) 17, a neutrophilic inflammatory response as observed in global IL-4Ralpha-d

106 ion, the VbrK C86S mutant induces a stronger inflammatory response at the early stage of infection, a

107 t is important for the development of type 2 inflammatory responses at mucosal surfaces.

108 ysis, has been extensively used to stimulate inflammatory responses both in vivo and in vitro LPS sti

109 on gamma was shown to contribute to the host inflammatory response but not bacterial clearance.

110 ular patterns, mito-DAMPs) triggers a potent inflammatory response, but their role in fibrosis is unk

111 ing body of evidence shows that altering the inflammatory response by alternative macrophage polariza

112 nd cationic peptides, and down-regulates the inflammatory response by engaging siglecs.

113 Derepression of SOCS3 enhances the anti-inflammatory response by inhibiting JAK/STAT-signaling a

114 lammasome activation is a constituent of the inflammatory response by recognizing pathogen and host-d

115 onsidered that constituent mechanisms of the inflammatory response can be actively manipulated in ord

116 y important in monitoring neurotransmission, inflammatory responses, cardiovascular systems, etc.

117 ays, and 28 days after injury to investigate inflammatory response, cartilage development, bone depos

118 the contributions of SOCS1 in regulating the inflammatory response characteristic of multisystem infl

119 P was associated with IL-17 signaling, acute inflammatory response, complement-mediated inflammation,

120 luded pancreatic lipase levels, the systemic inflammatory response (concentrations of leukocytes), fe

121 ns by Toll-like receptor 4 (TLR4) induces an inflammatory response; controlled responses confer immun

122 To help ameliorate the inflammatory response, corticosteroids are used as an ad

123 We hypothesized that inflammatory responses could be independent of antioxida

124 pe mice induced the DNA damage response, the inflammatory response, dedifferentiation and cell death

125 at targets signaling proteins, which mediate inflammatory responses.(,) Deletion of miR-146a in mice

126 , HA degradation occurs when an overreactive inflammatory response, derived from tissue trauma or neu

127 The mechanisms of ischemic injury and inflammatory response differ greatly between the immatur

128 droxymethylated regions were associated with inflammatory response/disease, organismal injury, and re

129 n severe asthma except for 3 associated with inflammatory responses driven by TNF and Toll-like recep

130 ages play an important role in regulating an inflammatory response during a urinary tract infection.

131 Thus, targeting the intestinal inflammatory response during infection could significant

132 e, the effect of pioglitazone to control the inflammatory response during IRI progression was examine

133 chemokines and cytokines associated with the inflammatory response during RSV infection (i.e., CCL-2,

134 NF-alpha), a critical cytokine linked to the inflammatory response during skeletal muscle regeneratio

135 aracterized by high viral load, uncontrolled inflammatory response, dysregulated adaptive immunity, c

136 trongly upregulate several genes involved in inflammatory responses (e.g., Saa4), cell migration (e.g

137 Gene networks dysregulated in PMD included inflammatory response, early/late E2-response, and chole

138 taSPT), the SL-null strain elicited a robust inflammatory response (elevated IL-1beta, IL-6, IL-10, I

139 sed to MIA can be temporarily rescued by the inflammatory response elicited by the administration of

140 A multidimensional inflammatory response ensues after status epilepticus (S

141 Conversely, smoking heightened the inflammatory response evident by change in the expressio

142 munication, as a mechanism through which the inflammatory response facilitates muscle regeneration af

143 delivery, and the triggering of detrimental inflammatory responses following innate immune recogniti

144 aB targets, IFNgamma/IFNalpha responses, and inflammatory response gene expression in macrophages.

145 gical control of excess perioperative stress-inflammatory responses has been shown to be clinically f

146 nd progression of HD are associated with the inflammatory response; however, the underlying molecular

147 ere no differences in hyperoxia-induced lung inflammatory response immediately after exposure or at P

148 tered molecular profile mainly associated to inflammatory response, immune cell trafficking, and infe

149 There was a significantly modulated inflammatory response in (Analysis of variance, p = 0.04

150 This was associated with an increased pro-inflammatory response in endothelial cells and the subse

151 scaffold, GIV (a.k.a. Girdin), titrates such inflammatory response in macrophages.

152 The inflammatory response in male intestine was significantl

153 asmin, have diverse functions related to the inflammatory response in mammals.

154 In this study, we characterized the inflammatory response in murine peritonitis and unexpect

155 ase and activation of cytosolic DNA-mediated inflammatory response in neurons.

156 sms, islet-resident macrophages underlie the inflammatory response in obesity and mechanistically par

157 se as well as the cerebral pro-oxidation and inflammatory response in passive hyperthermia.

158 l role in periodontal tissue homeostasis and inflammatory response in periodontitis.

159 iated maternal immune activation leads to an inflammatory response in the developing embryonic mouse

160 ous preterm labor is frequently caused by an inflammatory response in the gestational tissues elicite

161 hma, because it stimulates and amplifies the inflammatory response in this condition.

162 s a mechanism by which AMs restrain allergic inflammatory responses in airway ECs.

163 vation of the AHR pathway downmodulates skin inflammatory responses in animal models and psoriasis cl

164 103 reduces tissue injury and IRI-associated inflammatory responses in models of both warm ischemia (

165 uclear NF-kappaB DNA-binding and thereby pro-inflammatory responses in monocytes and dendritic cells.

166 s their inhibition attenuated scratching and inflammatory responses in mouse atopic dermatitis models

167 ver, relatively scarce data on profiling the inflammatory responses in pediatric TB are available.

168 MEs play a crucial role in facilitating anti-inflammatory responses in S. exigua.

169 onal Mfn2 overexpression, whereas peripheral inflammatory responses in the blood, heart, lung, and sp

170 polarization, thereby impacting pathological inflammatory responses in the brain.

171 Cibinetide ameliorated the local inflammatory responses in the liver and improved glycemi

172 oV-2 and develop bronchopneumonia and strong inflammatory responses in the lungs with neutrophil infi

173 atory microenvironment, thus alleviating the inflammatory responses in UC.

174 aggregates and to avoid complement-mediated inflammatory responses, in order to lower the risk for v

175 tion of reactive oxygen species, triggers an inflammatory response including activation of IL-6, and

176 Interestingly, animals with anti-inflammatory responses including high IL-10:IL-6 and kyn

177 1 in gammadelta and CD4 T cells controls the inflammatory response induced by IMQ.

178 Several studies have revealed that the hyper-inflammatory response induced by severe acute respirator

179 ype-I interferon and interleukin-6-dependent inflammatory responses, infection results in robust enga

180 In parallel, the host inflammatory response is characterized by epigenetic mod

181 Control of the inflammatory response is critical to maintaining homeost

182 The inflammatory response is ineffective in clearing the inf

183 natural host, and the paradoxical hMDMs' pro-inflammatory response is likely an evolutionary accident

184 Although a robust inflammatory response is needed to combat infection, thi

185 However, a Th2 allergic inflammatory response is suggested by the presence of IL

186 The inflammatory response is typified by astrocytosis, micro

187 A key event driving these inflammatory responses is the burst of reactive oxygen s

188 oronavirus 2 (SARS-CoV-2) incites a profound inflammatory response leading to tissue injury and organ

189 Pulmonary inflammatory responses lie under circadian control; howe

190 Although the host inflammatory response limits spread of and eventually cl

191 uding emergence of interferon (IFN)-mediated inflammatory responses, loss of surfactant proteins, and

192 (M2-like) become overwhelmed, activating an inflammatory response (M1-like).

193 ns of the human brain that a neuron-specific inflammatory response may precede insoluble Abeta plaque

194 Quantification of the associated inflammatory response may provide insight into the patho

195 rance mechanisms and/or promotion of an anti-inflammatory response may slow or prevent disease progre

196 vere burns, are accompanied by an immune and inflammatory response, metabolic changes and distributiv

197 Moreover, we postulated that inflammatory-response might underlie development of key

198 Combining 3K3A-aPC with fIIai reduced the inflammatory response, mimicking the fXai-associated eff

199 we compare the efficacy and carrier-induced inflammatory response of two polymeric microparticle (MP

200 virus replication and in suppressing the pro-inflammatory responses of human pathogenic viruses, incl

201 oited to decipher the key mechanisms driving inflammatory responses of MeONPs.

202 ory bowel diseases (IBDs) and differences in inflammatory responses of patients with ulcerative colit

203 opposed to the classical transient and acute inflammatory responses of the innate immune system.

204 is disease is thought to lead to an aberrant inflammatory response or cytokine storm, which contribut

205 eletion in keratinocytes does not dampen the inflammatory response or their proliferation, which coul

206 o the host in terms of increasing anti-viral inflammatory responses or restricting viral replication

207 as well as tumour growth and other systemic inflammatory responses originating deeply in soft tissue

208 We hypothesized that the CSF inflammatory response pattern after surgery would differ

209 rough transcriptional rewiring toward innate/inflammatory response programs.

210 ta indicate that RvD1 therapy can dampen the inflammatory response, promote the resolution of T. cruz

211 Exacerbated macrophage-mediated inflammatory responses promoted renal scarring and compr

212 h a distinct cleavage site and promotes anti-inflammatory responses, prosurvival, and endothelial bar

213 oural changes after the transient peripheral inflammatory response remain elusive.

214 pressive histone methylation dynamics during inflammatory responses remain enigmatic.

215 w that NFAT5, an activator of macrophage pro-inflammatory responses, represses Toll-like receptor 3 a

216 An uncontrolled inflammatory response results in chronic inflammation, o

217 A successful acute inflammatory response results in the elimination of infe

218 regulation of innate and adaptive immune and inflammatory responses, selective degradation of intrace

219 gether with interventions to abrogate stress-inflammatory responses, should be evaluated in conjuncti

220 g immune responses, regulation of immune and inflammatory response signaling pathways, and in the res

221 s significantly altered proteins involved in inflammatory response, such as CXCL1, CXCL6, PDGF-A, MCP

222 onse syndrome, followed by compensatory anti-inflammatory response syndrome (CARS).

223 In the latter, a post-infectious inflammatory response syndrome (PIIRS) is associated wit

224 tive was to compare time to meeting systemic inflammatory response syndrome (Sepsis-2) criteria, Sequ

225 The systemic inflammatory response syndrome (SIRS) frequently occurs

226 surgery, and variceal bleeding; R: systemic inflammatory response syndrome (SIRS), spontaneous bacte

227 Inclusion of both systemic inflammatory response syndrome and Sequential Organ Fail

228 Systemic inflammatory response syndrome and Sequential Organ Fail

229 ing a definition of sepsis based on systemic inflammatory response syndrome criteria and Blantyre cen

230 or suspected infection, two or more systemic inflammatory response syndrome criteria, and at least ca

231 meeting greater than or equal to 2 systemic inflammatory response syndrome criteria, Sequential Orga

232 l/L (91.3%; 95% CI, 89.0-93.2), and systemic inflammatory response syndrome plus organ dysfunction (6

233 Using systemic inflammatory response syndrome resulted in earlier elect

234 ghly resistant to endotoxin-induced systemic inflammatory response syndrome symptomatology and mortal

235 hus, a combination of inflammatory (systemic inflammatory response syndrome) and organ dysfunction (S

236 ile local inflammation that induces systemic inflammatory response syndrome, followed by compensatory

237 cute respiratory distress syndrome, systemic inflammatory response syndrome, sepsis, acute kidney inj

238 ere 9,087 patients (54.7%) that met systemic inflammatory response syndrome-first a median of 26 minu

239 ere 39% greater in patients who met systemic inflammatory response syndrome-first compared with those

240 ncreatitis; fistulas; or persistent systemic inflammatory response syndrome.

241 iral detection and had more intense systemic inflammatory response than those carrying non-PnIST or n

242 sis (CF) lung disease is characterized by an inflammatory response that can lead to terminal respirat

243 te apoptosis, which fuels a robust secondary inflammatory response that drives ALD.

244 o, it was able to attenuate an overly robust inflammatory response that is detrimental to the host du

245 Caenorhabditis elegans possess a mild inflammatory response that is not active in the muscle,

246 uction of antigens without inducing a strong inflammatory response that would lead to abortion.

247 sly found that cytolytic CD8 T cells promote inflammatory responses that are difficult to treat with

248 Helicobacter pylori induces strong inflammatory responses that are directed at clearing the

249 ss or mitochondrial stress, can also promote inflammatory responses that contribute to the chronic in

250 by innate immune dysfunction and exaggerated inflammatory responses that contribute to tissue injury.

251 or animal is needed to understand localized inflammatory responses that results during host-pathogen

252 CoV-2 induces the multisystem and multiorgan inflammatory responses that, collectively, contribute to

253 ite replication is responsible for eliciting inflammatory responses, the severity of disease symptoms

254 infarction reduced the systemic and cardiac inflammatory response through direct actions on both the

255 test the hypothesis that a chronic systemic inflammatory response to a gastrointestinal infection wo

256 onstrated its capacity to generate a similar inflammatory response to a wild-type rabbit strain and,

257 ns elusive and a better understanding of the inflammatory response to infection is required to identi

258 eam genes that modulate ciliary function and inflammatory response to influence asthma.

259 e 1 IFN and virus replication.IMPORTANCE The inflammatory response to influenza A virus (IAV) partici

260 ung macrophages are important in mounting an inflammatory response to injury, but they are also invol

261 ays an essential role in dampening the early inflammatory response to LPS by regulating macrophage fu

262 co-infection may modulate the intracerebral inflammatory response to M. tuberculosis and improve TBM

263 emokine gene promoters, facilitating a rapid inflammatory response to microbial pathogens.

264 Helminth infections may modulate the inflammatory response to Mycobacterium tuberculosis and

265 ically triggered by an overwhelming systemic inflammatory response to pathogens, and may lead to seve

266 The inflammatory response to periodontal pathogens is dynami

267 and the putative etiology is a dysregulated inflammatory response to SARS-CoV-2 infection.

268 The inflammatory response to severe acute respiratory syndro

269 l-associated lymphoid tissue (NALT), a muted inflammatory response to the Deltargg2 bacteria suggests

270 The inflammatory response to the fungus Pneumocystis jirovec

271 s-on-a-chip and display a more dynamic, less inflammatory response to TNFalpha, that resembles more t

272 F phenotypes including growth regulation and inflammatory responses to airway bacterial challenge.

273 ate inflammasomes but then subvert resulting inflammatory responses to avoid elimination.

274 d be a potential drug target in neutrophilic inflammatory responses to avoid exaggerated nonapoptotic

275 n the absence of disease symptoms or notable inflammatory responses to cause primary pneumonic plague

276 ted from EHS mice showed markedly attenuated inflammatory responses to LPS challenge.

277 ause it must avoid the activation of harmful inflammatory responses to the microorganisms while prese

278 issue invasion by microorganisms and tempers inflammatory responses to the myriad contents of the lum

279 complex can act to suppress host macrophage inflammatory responses to the proinflammatory beta -gluc

280 In the gills, the balance between inflammatory responses to waterborne pathogens and regul

281 2(DeltaLysM) macrophages show attenuated pro-inflammatory responses toward Toll-like receptor-2 and -

282 umerous factors, including excess stress and inflammatory responses, tumour-cell shedding and pro-ang

283 l growth factor were identified as important inflammatory responses underlyingair pollution-associate

284 or kappaB) signaling pathway, modulating the inflammatory response upon LPS stimulation.

285 e hypothesized that M. tuberculosis-specific inflammatory responses used to identify latent tuberculo

286 rical treatments have aimed at reversing the inflammatory response using immunomodulatory medications

287 elination by promoting myeloid cell-mediated inflammatory responses via TNF-alpha, which are essentia

288 nfection of nonpregnant mice, the local lung inflammatory response was contained to the lungs and was

289 vent microbiota from inducing a pathological inflammatory response, we found that reducing the microb

290 Several transcriptional pathways involved in inflammatory response were positively enriched in the CL

291 TLR7-dependent inflammatory responses were differentially regulated by

292 ntegration, biodegradation, and minimal host inflammatory responses when the antimicrobial cryogels,

293 photodynamic therapy is used to initiate the inflammatory response which further mediated the accumul

294 , that these mice are "primed" for a corneal inflammatory response, which once initiated, would persi

295 f the porous materials did not cause intense inflammatory response, which revealed good compatibility

296 A major cause of damage is local inflammatory responses, which may spread to produce more

297 expressed genes were mainly associated with inflammatory responses, which might contribute to the pa

298 pancreatitis is characterized by a profound inflammatory response with local and systemic implicatio

299 a, epithelial-to-mesenchymal transition, and inflammatory responses with significantly more severe le

300 l lysozyme balances intestinal anti- and pro-inflammatory responses, with implications for IBD.