ライフサイエンスコーパス: inflict

1 and deformity that scoliosis can insidiously inflict.

2 r protect their tissues from the damage they inflict.

3 n during the insult that an injury was being inflicted.

4 ides, and a 3 mm wide wound was mechanically inflicted.

5 lative to rFVIII after tail vein transection inflicted 24 hours after dosing.

6 ost needlestick or sharps injuries were self inflicted (711 [87%] of 817) and involved a hollow-bore

7 blic goods are equally accessible to all but inflict a fitness cost on individual producers is a long

8 sume that moderately destabilizing mutations inflict a fitness penalty proportional to the reduction

9 udies whereby people can pay a small cost to inflict a heavy loss on a punished individual.

10 raction whereby both cell types co-exist and inflict a minimal degree of harm on each other.

11 can adapt to poultry and mammalian species, inflicting a great socioeconomic burden on farming and h

12 y tract in the majority of patients, without inflicting a high radiation dose on the patient.

13 ethods commonly isolate and sacrifice cells, inflicting a perturbed state and preventing complementar

14 roduction, to liver-implanted rabbit tumors, inflicts a rapid, lethal blow to most cancer cells there

15 We suggest that IL-23 inflicts a repurposing of the adaptive cytotoxic effecto

16 us influenzae, and Streptococcus pneumoniae, inflicts a substantial burden of disease worldwide.

17 derstanding about how children present after inflicted abdominal or skeletal trauma.

18 ulfate sodium (DSS), and the severity of the inflicted acute colitis was determined.

19 live pathogen often impairs DC function and inflicts additional damage on the host.

20 st a model where p53 activates topo I, which inflicts additional genomic damage after the initial UV

21 CD4 and CD8 T cells do have the capacity to inflict adjacent tissue damage and that this injury is g

22 ich secretes AMPs, can remain immune to self-inflicted AMP-induced apoptosis.

23 nt to M. haemolytica-caused pneumonia, which inflicts an economic loss of over $1 billion to the US c

24 Malaria inflicts an enormous burden on global human health.

25 ichia coli (ETEC), an E. coli pathotype that inflicts an enormous global disease burden.

26 ion in FRH was driven by a reduction in self-inflicted and undetermined injuries.

27 s slides, a 3-mm-wide wound was mechanically inflicted, and wound fill on days 4, 6, and 9 was report

28 r (Tfh) cells, whose excessive responses can inflict antibody-mediated autoimmunity.

29 In accordance, HlyA was unable to inflict any [Ca(2+)]i oscillations in 132-1N1 cells, whi

30 family are characterized by their ability to inflict apoptosis upon binding to their cognate receptor

31 tial studies are the result of cycloheximide-inflicted artifacts.

32 We conclude that cerebellar damage inflicted at a young age is not necessarily better compe

33 ) T cells, and inhibit tumour growth without inflicting autoimmunity.

34 e to acceleration of beta amyloidosis in HIV-inflicted brains, and modulation of macrophages may be a

35 and there is much interest in how such self-inflicted breaks are effectively managed.

36 infection in a 21-year-old male after a self-inflicted burn injury.

37 DNA damage inflicted by a functional C-terminal domain is required

38 RBC membrane disruptions inflicted by a mode-locked Ti:sapphire laser, even those

39 ke the synapses more resistant to the insult inflicted by Abeta.

40 mably to fine-tune activity and limit damage inflicted by activated RPS4 protein.

41 ponse to ultraviolet radiation or DNA damage inflicted by adriamycin, and reveal that serine 15 is cr

42 are recognized as the main cytotoxic lesion inflicted by an array of alkylating compounds used in ca

43 ut protect the opposite pole from the damage inflicted by another, immediate application of SW.

44 Clonal loss-of-function, inflicted by blastomere transplantation or gene-transfer

45 ling molecule able to amplify the cell lysis inflicted by certain bacterial toxins including the two

46 w perspective for the potential health risks inflicted by endogenous formaldehyde and may inform impr

47 The renal injury inflicted by expression of the folding mutants was marke

48 The moderate and mild traumatic injury was inflicted by focal laser lesion and by mild photo-damage

49 ems to build a science of repairing the harm inflicted by humans on natural environment.

50 ation, thus exclusively counteracting damage inflicted by immune responses.

51 t regulators to protect the self from damage inflicted by inadequate complement activation.

52 e immune system to recover from the injuries inflicted by infection.

53 umors are not determined by exogenous damage inflicted by inflammatory cells.

54 -strand breaks (DSB), the most lethal lesion inflicted by IR.

55 el factors required for repair of DNA damage inflicted by IR.

56 By contrast, after chronic injury inflicted by iterative hepatotoxin (carbon tetrachloride

57 ted deaths (i.e., fatalities due to injuries inflicted by law enforcement officers) undercount these

58 tosis in response to injuries, such as those inflicted by macrophage-produced TNF alpha and NO.

59 e therapeutics to counter the high mortality inflicted by malaria.

60 hat helps tumor cells survive the DNA damage inflicted by many chemotherapy agents.

61 the same time repairing the vascular damage inflicted by neutrophil activation, thereby maintaining

62 ut nursing home residents' injuries that are inflicted by other residents.

63 ify factors associated with violent injuries inflicted by partners and those inflicted by persons oth

64 ent injuries inflicted by partners and those inflicted by persons other than the partners of the vict

65 hat aging is largely due to molecular damage inflicted by reactive oxygen species, electrophiles, and

66 Lung injuries inflicted by recurring infection and excessive inflammat

67 n loss in three non-coding nucleic acids was inflicted by replacement of a duplex stem with unstructu

68 lling, and RNA repair neutralizes the damage inflicted by ribotoxins for cell survival.

69 tRNA anticodon damage inflicted by secreted ribotoxins such as fungal gamma-to

70 Their ability to promptly respond to insults inflicted by stress-causing microbes strongly suggests t

71 ention for reversal of impaired neurogenesis inflicted by Tat and cocaine.

72 tRNA damage inflicted by the Escherichia coli anticodon nuclease Prr

73 y influenza virus, mirroring the destruction inflicted by the highly pathogenic 1918 'Spanish' influe

74 13-induced damage or a double-stranded break inflicted by the HO endonuclease.

75 DNA repair systems to repair the DNA damage inflicted by the host during infection, but the role of

76 e-enhancing response to bacterial DNA damage inflicted by the host immune system.

77 DNA repair pathways to resist genomic damage inflicted by the host.

78 CSC-treated pigs, indicating that the damage inflicted by the infarct in the 2 groups was similar; 1

79 haracteristics, but neither explained damage inflicted by the other.

80 susceptible to endolysosomal membrane damage inflicted by the pathogens and noxious particles they in

81 of physical, emotional, and sexual violence inflicted by their spouses.

82 nd-organ targeting Abs, the extent of damage inflicted by these Abs may be heavily dependent on cues

83 ver, the structural nature of the DNA damage inflicted by this drug remains poorly understood.

84 ceptibility to grazers, but allocation costs inflicted by this plastic morphological defense are poor

85 Importantly, when administered to mice inflicted by TLR2, but not TLR4-driven lethal inflammati

86 lored and thus the tremendous disease burden inflicted by type 2 diabetes alleviated.

87 ole in preventing autoimmunity and pathology inflicted by uncontrolled immune responses to infections

88 o reveal and analyze gene expression changes inflicted by various physical and chemical environmental

89 can reduce the amount of punishment actually inflicted, by "tipping" a situation from its high-violat

90 Hurricanes can inflict catastrophic property damage and loss of human l

91 overproduction of oxygen free radicals that inflict cell damage.

92 duce apoptosis as a secondary consequence of inflicting cell damage.

93 of select cellular proteins, Ebola virus GP inflicts cell damage and may facilitate immune escape by

94 Like wild type, stv1Delta was able to inflict cellular damage in Caco-2 and macrophage cells,

95 ARs trigger multiple deleterious cascades to inflict cellular damage on both neurons and glia during

96 damaging macrophage functions, they directly inflict cellular injury within the arterial wall.

97 activity of both fusion partners and without inflicting chemical damage on the proteins to be joined.

98 ctivated while minimizing their potential to inflict collateral damage to the adjacent lung tissue an

99 nt that antisocial children often grow up to inflict considerable damage on others at a high cost, an

100 humans unnoticed for years or even decades, inflicting continuous damage that can culminate later in

101 Individuals with enhanced abilities to inflict costs (e.g., stronger individuals) or to confer

102 It involves inflicting costs on defectors; and though the costs for

103 rpersonal negotiating tactics (conditionally inflicting costs or conditionally withholding benefits)

104 These then inflict cytotoxicity through downstream activation of th

105 ey invade, and they use neurotransmitters to inflict damage and create room for growth.

106 We report here that viruses that do not inflict damage on beta cells provided protection from T1

107 In addition to their ability to directly inflict damage on macromolecules, ROS and RNS indirectly

108 y, ischemia can also induce this pathway and inflict damage on native cells.

109 gnificant fraction of the oxidants escape to inflict damage upon the vesicular assemblies.

110 ructure closely related to ceramide, did not inflict damage.

111 ey protect themselves from GrB-mediated self-inflicted damage are unknown.

112 fitness by protecting symbiosis against host-inflicted damage during development and by controlling p

113 ionary adaptation allowing DHP to avoid self-inflicted damage in the oxidative environment.

114 from progenitors that are refractory to self-inflicted damage, rather than derived from fully differe

115 ttle is known about how bacteria escape HOCl-inflicted damage.

116 opper in reaching vital destinations without inflicting damage or becoming trapped in adventitious bi

117 zed reaction under native conditions without inflicting damage to the target membrane or cell.

118 e been recognized to participate in the self-inflicted damaging immune responses that characterize au

119 period characterised by a sharp rise in self-inflicted deaths.

120 se of malaria outside sub-Saharan Africa and inflicts debilitating morbidity and consequent economic

121 These results indicate that the tumor-inflicted deficits of TILs are reversible.

122 Modern war ballistics and blast injuries inflict devastating extremity injuries, violating soft t

123 ite manages to infect, invade and ultimately inflict devastating tissue destruction.

124 hly malignant paediatric brain tumour, often inflicting devastating consequences on the developing ch

125 riggers harmful inflammatory responses as it inflicts direct tissue damage.

126 sm rupture and subarachnoid hemorrhage (SAH) inflict disability and death on thousands of individuals

127 factors and hijacks the rice BR machinery to inflict disease.

128 and peroxynitrite close to the cell nucleus, inflicting DNA damage, but the source of reactive oxygen

129 t cells to arrest during their cell cycle by inflicting DNA damage.

130 ymes allowed us to study the consequences of inflicting DNA nicks at EcoRI sites in vivo.

131 rn impairs proper chromosome segregation and inflicts DNA damage on the daughter cells.

132 iate homolog segregation and arise from self-inflicted double-strand breaks (DSBs).

133 discharge following adversity-related (self-inflicted, drug-related or alcohol-related, or violent i

134 sion with adversity-related injury (ie, self-inflicted, drug-related or alcohol-related, or violent i

135 suggest that the animal models tested do not inflict DSBs on the mycobacterial chromosome, that other

136 d showed that other predominant immune cells inflicted during A. hydrophila infections, such as murin

137 breaks with 2',3'-cyclic-PO4 and 5'-OH ends inflicted during tRNA splicing and non-canonical mRNA sp

138 Imaginal disc damage inflicted early in larval development triggers developme

139 ections may predispose to atherosclerosis by inflicting endothelial injury.

140 ouse colitis model, we found that Salmonella-inflicted enteropathy elicits parallel blooms of the pat

141 ntigens while preventing autoreactivity from inflicting escalating damage.

142 However, it is difficult to assess damage inflicted exclusively by DSAs when alloreactive T cell a

143 Our results indicate that the parasite inflicts extensive damage leading to subsequent death of

144 Urinary tract infections (UTIs) inflict extreme pain and discomfort to those affected an

145 More specifically, we assume that mutations inflict fitness penalties proportional to the extent tha

146 es the intracompartmental pressure of CS but inflicts further tissue damage.

147 squamous cell carcinoma (SCC) genesis should inflict genomic alterations not only on the epithelium b

148 Self-inflicted gingival injuries have been known to occur in

149 Moreover, predators caused grasshoppers to inflict greater damage to herbs and lesser damage to gra

150 erties of automotive engines, where bearings inflict greater forces on the crankshaft when operated u

151 Self-inflicted gunshot wounds (SIGSWs) are a common method of

152 -old woman with a history of repetitive self-inflicted handheld laser exposure was found to have bila

153 er retinal streaks were associated with self-inflicted handheld laser injury.

154 is generally defined as incurring a cost to inflict harm on a wrong-doer.

155 o challenge the perceived power of voices to inflict harm on the voice hearer if commands are not fol

156 aged 9 months or less, all of whom died from inflicted head injuries, and 14 control infants who died

157 ffuse axonal injury is an uncommon sequel of inflicted head injury in children.

158 ominant histological abnormality in cases of inflicted head injury in the very young is diffuse hypox

159 ce of a history, it is important to consider inflicted head trauma in infants and young children pres

160 ncluding sexual abuse, physical child abuse, inflicted head trauma, and child abuse prevention.

161 eter-related bloodstream infections (CRBSIs) inflict health impairment and high costs.This study inve

162 tentially limiting the propensity of HOCl to inflict host tissue damage that can lead to inflammatory

163 membrane oxidation and enters the cytoplasm inflicting hydroxyl radical attack on intracellular prot

164 Injuries were considered inflicted if accompanied by a confession or a medical an

165 chistosoma mansoni and Schistosoma japonicum inflict immense suffering as agents of human schistosomi

166 n, we show that an environmental disturbance inflicted in early gestation can induce subtle cytoarchi

167 mergency departments were attributed to self inflicted injuries among children (26,045 males and 51,3

168 cy department visits (ED) attributed to self inflicted injuries and attempted suicides among children

169 y potential methods of such intentional self inflicted injuries and attempted suicides.

170 Self inflicted injuries by poisoning were the most frequently

171 to 2013 with the admitting diagnosis of self-inflicted injuries via firearms.

172 an External Cause of Injury for any of self inflicted injuries were selected.

173 on models were used to compare children with inflicted injuries with those with noninflicted injuries

174 cide were current and past diagnoses of self-inflicted injuries, major depression, bipolar disorder,

175 Limitation: Exclusion of self-inflicted injuries, misclassification of intent, and asc

176 r proportion of ED visits attributed to self inflicted injuries.

177 notin compounds, and is known to selectively inflict injury to specific regions of the brain.

178 causes of death were overdose (57.9%), self-inflicted injury (13.2%), trauma/accidents (10.5%), and

179 sks of suicide were increased following self-inflicted injury (adjusted subhazard ratio 5.11 [95% CI

180 larly after any drug/alcohol-related or self-inflicted injury (i.e., with/without violent injury), fo

181 iodontitis and suggested a diagnosis of self-inflicted injury associated with mental retardation.

182 Corn seedlings respond to insect herbivore-inflicted injury by releasing relatively large amounts o

183 of the immune system can also result in self-inflicted injury culminating in autoimmune and allergic

184 n for violent, drug/alcohol-related, or self-inflicted injury have increased risks of subsequent harm

185 s also paid to the importance of considering inflicted injury in the differential diagnosis of every

186 eir supporting functions while avoiding self-inflicted injury is poorly understood.

187 y ill and injured children due to abusive or inflicted injury represent a growing challenge for pedia

188 practice to reduce risks of harm after self-inflicted injury should be extended to drug-related or a

189 , children who incurred an increased risk of inflicted injury were born to young mothers (< or =21 ye

190 hysical abuse with a focus on the child with inflicted injury who is admitted to the pediatric intens

191 jury (violent, drug/alcohol-related, or self-inflicted injury) has been described as a "teachable mom

192 s of violent, drug/alcohol-related, and self-inflicted injury, but particularly after any drug/alcoho

193 Once considered a self-inflicted injury, pancreatitis is now recognized as a co

194 anzyme B (GrB), Spi6 protects CTLs from self-inflicted injury.

195 jury (violent, drug/alcohol-related, or self-inflicted injury; n = 333,009) or for accident-related i

196 closely associated with an increased risk of inflicting injury as a result of domestic violence were

197 the protective pain pathway of predators by inflicting intensely painful stings.

198 f age and among those with unintentional and inflicted (intentional) injuries also showed no differen

199 se the midgut via an intracellular route and inflict irreversible damage to the invaded cells.

200 The epithelial damage inflicted is repaired efficiently by an actin purse-stri

201 ns open pathways for neighboring networks to inflict large cascades.

202 ty to metabolites and/or drug molecules, and inflicts large-scale changes in metabolism.

203 In contrast, accidental and peer-inflicted laser injuries were found to result in focal f

204 d loss on spectral-domain OCT following peer-inflicted laser injury.

205 especially in livers exposed to agents that inflict lasting mutagenic DNA damage.

206 especially in livers exposed to agents that inflict lasting mutagenic DNA damage.Oncogene advance on

207 nd radioembolization with use of yttrium 90, inflict lethal insult to tumors while preserving normal

208 al cancer therapy is a promising new tool to inflict localized and irreversible damage to tumor tissu

209 n of lung injury from a form of patient self-inflicted lung injury.

210 ibitor, had increased susceptibility to self-inflicted lysis because of increased NE activity.

211 that could be used in a bioterror attack to inflict mass casualties.

212 be virulent parasites with the potential to inflict mass mortalities on hosts, causing e.g. changes

213 stant obese db/db mice or lipopolysaccharide-inflicted mice were associated with increased FoxO1 prod

214 ntly decreased Th but increased Tregs in EAE-inflicted mice, without apparent global immune suppressi

215 us of human-hamster hybrid (AL) cells, while inflicting minimal cytotoxicity.

216 ly deadly, this form of malaria continues to inflict misery on the millions of sufferers who have bee

217 (o)ortho - G(o)H or G(o)ortho - G(o)para) by inflicting molecular strain and consequently weakening t

218 glycolipid agonist of iNKT cells reduced SEB-inflicted morbidity/mortality.

219 sly generated as by-products of respiration, inflict more damage on the mitochondrial (mt) than on th

220 pathological inflammatory responses that can inflict more harm than the infection itself.

221 tis C virus, two common viral pathogens that inflict more than 10% of the population in the developin

222 oxidation, yet at an equal dose, anti-TM/GOX inflicted more severe lung injury than anti-PECAM/GOX.

223 n indicates that neither high levels of lion-inflicted mortality nor behavioural avoidance inflict su

224 s in which the top predator is a generalist, inflicting mortality upon the focal prey species, but it

225 omarkers may be used as a screening tool for inflicted neurotrauma.

226 Collapsing structures and swirling debris inflict numerous crush injuries, fractures, and serious

227 e examined what damage Th17 cell lines could inflict on allogeneic skin grafts in the absence of othe

228 ns from modifications the virulence proteins inflict on host target proteins.

229 se of the devastating diseases these viruses inflict on humans, animals, and plants.

230 he damage that artifacts, such as chimerism, inflict on index integrity.

231 of cells to damage that environmental forces inflict on macromolecules.

232 en influence the degree of damage herbivores inflict on their plant resources.

233 rld are much more than the collateral damage inflicted on civilians, infrastructure, environment, and

234 Continuous oxidative damage inflicted on DNA produces 7,8-dihydro-8-oxoguanine (8-ox

235 lenging due in part to the continuous damage inflicted on DNA, which results from its contact with re

236 amines may repair some of the damage that is inflicted on protein amines by HOCl.

237 investigated in excisional wounds that were inflicted on the back skin of control and mice lacking i

238 mical difference may be attributed to damage inflicted on the central pattern generator of locomotion

239 ity of data on the extent of molecular scars inflicted on the mouse genome.

240 The damage inflicted on the myocardium during acute myocardial infa

241 Graft dysfunction may result from damage inflicted on tubular epithelial cells by intratubular cy

242 n these circumstances is not attributable to inflicted or accidental trauma.

243 a lipopeptide-like sequence (C10OOc12O) that inflicted outer membrane damage at a low micromolar rang

244 rious stimuli, but if left unchecked, it can inflict oxidative damage on all types of biological macr

245 rous acid (HOCl) at sites of inflammation to inflict oxidative damage upon invading pathogens.

246 rms reactive chlorinating species capable of inflicting oxidative stress and altering protein functio

247 dopamine precursor levodopa on decisions to inflict pain on oneself and others for financial gain.

248 dowed with an ability to chase, capture, and inflict pain.

249 that most people show a greater aversion to inflicting pain on others than themselves.

250 rated into human conflict, with the goals of inflicting pain, destroying food, and transmitting patho

251 der in which sexual pleasure is derived from inflicting pain, suffering, or humiliation on others.

252 eptor 1 ligands suppress all features of flu-inflicted pathological inflammation and place the endoth

253 ated proteins may be a general mechanism for inflicting pathological conditions in various diseases.

254 uctural variants that can fuel evolution and inflict pathology.

255 ly used broad-spectrum antibiotics, but they inflict permanent hearing loss in up to ~50% of patients

256 the adaptations that allow scolopendrids to inflict physical damage on prey and predators.

257 ted errors destabilize neuronal signaling by inflicting primary disorders of membrane excitability an

258 honor patient autonomy against a concern of inflicting psychological harm.

259 en alpha and low-rankers allows the alpha to inflict punishment indirectly, thereby maintaining her r

260 ition of this beta-emitting scout dose could inflict radiation damage, the extent of which we aimed t

261 bris and promotes tissue repair, but it also inflicts secondary injury from inflammatory responses.

262 In field experiments, elephants inflicted severe damage on whistling-thorn trees from wh

263 ltiple arms of the host immune response, and inflicting severe damage to mucosal barriers, resulting

264 ally significant invasive species capable of inflicting severe feeding damage on many important tree

265 inity (NaCl) stress impairs plant growth and inflicts severe crop losses.

266 to prevent this pathogen from continuing to inflict significant damage on susceptible crop hosts.

267 jority of pediatric respiratory diseases and inflict significant economic loss, health care costs, an

268 s) are prevalent among diabetic patients and inflict significant morbidity and mortality.

269 Psoriasis and psoriatic arthritis inflict significant morbidity.

270 Qualitative evidence suggests that hirsutism inflicts significant negative impacts on quality of life

271 Mice lacking Bhlhb5 develop self-inflicted skin lesions and show significantly enhanced s

272 ct on the S-phase of T. brucei cell cycle by inflicting specific damage on the kinetoplast.

273 ions in which nature provides restoration or inflicts stress, and transactions that are more mutual,

274 enal gland, and its degradation products can inflict substantial protein damage via formation of adva

275 nflicted mortality nor behavioural avoidance inflict sufficient demographic consequences to translate

276 -beneficial behaviors may evolve if (a) they inflict sufficient fitness costs on outgroup individuals

277 of North Carolina children, the incidence of inflicted TBI varied by characteristics of the injured c

278 TBI were identified, with 80 (53%) incurring inflicted TBI.

279 situation where participants freely chose to inflict the same harms.

280 to be one of the primary causative cytokines inflicting the characteristic damage to hepatocytes seen

281 els was detected within the first 24 h after inflicting the injury; we present evidence suggesting th

282 e mechanism(s) by which oxidative DNA damage inflicts the genome.

283 ens and indirectly limit immune inflammation-inflicted tissue damage by employing multiple mechanisms

284 Damage inflicted to leaves by chewing insect larvae led to an i

285 We find that massive damage inflicted to the posterior or the dorsal compartment of

286 ble partial denture, oral piercing, and self-inflicted trauma), and thermal (due to overheated ultras

287 The incidence of inflicted traumatic brain injury (TBI) in US children is

288 he evaluation of unexpected infant death and inflicted traumatic brain injury are ongoing.

289 The incidence of inflicted traumatic brain injury in the first 2 years of

290 atment, including physical and sexual abuse, inflicted traumatic brain injury, and child neglect.

291 e burden of disease, death and economic loss inflicted upon the tropical world by this parasite.

292 nse of myeloid cells to inflammatory stress, inflicted via intraperitoneal administration of sodium c

293 hrough the damage that these large parasites inflict when migrating through host tissues.

294 50-micron thick where mechanical trauma was inflicted when slices were cut from brain.

295 Closed head TBI was inflicted with a mechanical device that subjects flies t

296 Fatal blows were inflicted with a wide range of velocities but often occu

297 s, South Africa afford being thrown so as to inflict worthwhile damage to a medium-sized animal over

298 sharply decrease at the margins of a freshly inflicted wound to increase again as healing begins.

299 igin of postoperative pain is the surgically inflicted wound, there is appeal to localized applicatio

300 t such breaks may explain the puzzling 'self-inflicted wounds' at the ends of the Mos1 transposon in