ライフサイエンスコーパス: informatic

1 ea of bioinformatics can be called 'bioimage informatics'.

2 osphorylation of Shp2 (Ptpn11 - Mouse Genome Informatics).

3 ironment, and eventually arriving in medical informatics.

4 n and 1-2 d for data analysis and downstream informatics.

5 or a very important problem in translational informatics.

6 atment, and for extending the field of image informatics.

7 ased healthcare and genotype-meets-phenotype informatics.

8 nisms demonstrate the importance of bioimage informatics.

9 gnancy and arrhythmias, quality of life, and informatics.

10 es as partners, and incorporation of medical informatics.

11 rs access to, and training in, proteogenomic informatics.

12 New technological and informatics advancements in population genomics are bein

13 Recent technological and informatics advances have led to unprecedented volumes o

14 We sought to determine whether an informatics algorithm applied to the EHR could electroni

15 An informatics algorithm can successfully identify both kno

16 We developed an informatics algorithm to search the EHRs of patients age

17 Informatic analyses of network connectivity, coexpressio

18 Through proteomics and informatic analyses of PEAK1-depleted PDAC cells, we def

19 Biochemical and informatics analyses conducted over the past few years h

20 rm effect on productive BKPyV infection, our informatics analyses indicate that the preferred target

21 Informatics analyses reported here show that RNA granule

22 Subsequent informatics analyses revealed a network of injury-respon

23 Using integrated informatics analyses, we constructed putative regulatory

24 Informatic analysis consisted of a training set that was

25 Informatic analysis of the P. syringae genome suggests o

26 In some cases, informatic analysis was used to restrict the space of po

27 Proteomic methods and informatic analysis were used to identify patterns of ur

28 ts with the prediction of vaccine targets by informatics analysis of genome sequences.

29 An unsupervised informatics analysis revealed that immune response and i

30 he development of experimental protocols and informatics analysis tools is helping to reduce sequenci

31 ucing big data at an unprecedented rate that informatic and artificial intelligence (AI) analytics si

32 Informatic and biochemical analysis suggests that large

33 high-content, multiplexed measurements with informatic and computational modeling methods to better

34 We have used a combination of bio-informatic and experimental approaches to engineer a cry

35 abilities, approaches, and tools of bioimage informatics and apply them to advance their own studies.

36 s as single-photon light sources for quantum informatics and biolabels for real-time monitoring of si

37 is labor-intensive and requires considerable informatics and biological expertise.

38 The workflow integrates group theory, informatics and density-functional theory to uncover des

39 of compounds have a long history in chemical informatics and drug discovery.

40 s between entomology and disciplines such as informatics and electrical engineering.

41 This combined informatics and functional approach has allowed the char

42 Comprehensive informatics and functional studies revealed a compartmen

43 als, the International Journal of Functional Informatics and Personalized Medicine and the Internatio

44 sign and International Journal of Functional Informatics and Personalized Medicine, IEEE 7th Bioinfor

45 ta may be leveraged with novel technologies, informatics and practical clinical paradigms to apply th

46 Indeed, significant advances in the informatics and software tools necessary to support the

47 netic screens has created the need for clear informatics and statistical approaches to deal with the

48 Clinical informatics and structured accessible secure data captur

49 , EBI's Ontology Working Group, Mouse Genome Informatics and the Monarch Initiative among others, and

50 e for pipetting, non-trivial tasks for which informatics and visualization tools can prevent costly e

51 tervention combining professional education, informatics, and financial incentives reduced the rate o

52 ecognition algorithms are useful in bioimage informatics applications such as quantifying cellular an

53 In this report, an informatic approach to the design of T-cell vaccines dir

54 Here we present an informatic approach, called high-resolution filtering (H

55 derived peptides were predicted by an immuno-informatics approach based on the HLA-A*02 binding motif

56 derived peptides were predicted by an immuno-informatics approach based on the HLA-A2 binding motif.

57 The informatics approach increased the number of products co

58 This new translational biomedical informatics approach supports not only detection of new

59 We introduce an informatics approach that uses publicly available data t

60 An informatics approach to evaluating combined chemical exp

61 To use an informatics approach to examine the association of ADT a

62 dy is to optimize an integrated experimental/informatics approach to more confidently characterize th

63 In applying this combined informatics approach to ricin A, we identified a conserv

64 A lipid-mediator informatics approach was employed to systematically iden

65 Here, employing an informatics approach, we define novel families of T6S pe

66 features it produces regulate the downstream informatics approach.

67 88 individuals with prostate cancer using an informatics approach.

68 In addition, we outline informatic approaches that correct for biases inherent i

69 We have employed novel informatic approaches to characterize the in vivo transc

70 hat combine phyloinformatic and biodiversity informatic approaches to document large scale biodiversi

71 in high throughput omics workflows, and new informatics approaches are necessary for processing the

72 Thus, bioimage informatics approaches are needed to rapidly and objecti

73 tions in vaccinology using computational and informatics approaches.

74 ch of the owner, using mass spectrometry and informatics approaches.

75 The growth of electronic publication and informatics archives makes it possible to harvest vast q

76 s in analytical chemistry, microbiology, and informatics are breaking down the barriers to a fuller a

77 cly available software packages for bioimage informatics are listed for further reference.

78 ontrols, reference materials, statistics and informatics are required for a robust measurement proces

79 individual genes permits the development of informatics-assisted methods for the selection of candid

80 Therefore, using an informatics based approach to identify STAT5 targets, we

81 We utilize an unbiased informatics based machine learning approach to classify

82 ing human and mouse isoforms, and utilize an informatics-based approach to identify a novel ninth MIT

83 To address this issue, we have undertaken an informatics-based approach to understand the genetic and

84 We combine available experimental data with informatics-based immunological predictions to help desi

85 esent study, HITS data were compared with an informatics-based list of putative substrates of the per

86 r hope is to stimulate experimental tests of informatics-based predictions for TGFbeta signaling, as

87 thus impractical in high throughput studies, informatics-based statistical learning approaches can be

88 itional sequence comparisons and discuss the informatic basis for the ability of the PFM approach to

89 eating entirely new possibilities for cancer informatics by enhancing data discovery and retrieval.

90 Additional informatics can conceivably be developed to mine and int

91 lysis, computational drug discovery, medical informatics, cancer genomics, and systems biology.

92 ke advantage of its screening, chemistry and informatic capabilities, and provides a brief summary of

93 ow and in the future, is to provide powerful informatics capabilities to T1D scientists in a form the

94 yside and Fife were identified by the Health Informatics Centre (HIC) and invited to take part in the

95 All data were anonymised according to Health Informatics Centre standard operating procedures.

96 provided by the University of Dundee Health Informatics Centre, who have access to health-related po

97 s paper provides an overview of the bioimage informatics challenges and approaches in image-based stu

98 We introduce the informatics challenges arising in the analysis of tiling

99 types and huge data volume poses formidable informatics challenges for base calling, read alignment

100 One of the major informatics challenges is providing tools that link meta

101 his technique also poses many biological and informatics challenges to extracting meaningful biologic

102 ge data sets that analysis poses significant informatics challenges, particularly for research groups

103 scientific, infrastructural, logistical, and informatics challenges.

104 The Medical Informatics Committee of the American College of Physici

105 A central challenge for the biodiversity informatics community is to provide the means to share a

106 l for biodiversity science, the biodiversity informatics community must address several critical chal

107 e present the recent efforts by the bioimage informatics community to tackle these challenges, and di

108 r has become a critical tool for the pathway informatics community, detecting thousands of errors and

109 ents and practicing radiologists outside the informatics community.

110 transcripts as enriched in the VMP using bio-informatic comparisons of Tag-seq and RNA-seq data, and

111 One goal of the informatics component of our project has been to generat

112 y dissipation in the memory and other binary informatics components are insignificant compared to the

113 to fundamental RNA-seq molecular biology and informatics concepts.

114 at established the International Arabidopsis Informatics Consortium (IAIC).

115 benefits include reduced infrastructure and informatics costs in managing and analyzing large sequen

116 lation hosted by the UIC Center for Research Informatics (CRI) at galaxy.cri.uic.edu.

117 t cardiovascular disease care innovations in informatics, data uses, patient engagement, continuous l

118 ion of clinical approach with a more formal, informatics-derived approach to characterization and a B

119 which can be easily parsed due to accessible informatics-derived image analysis tools, can provide bo

120 with a speculative discussion of what future informatics developments may hold for cognitive neurosci

121 rt 1 of this review on the basics of imaging informatics discussed the elements that make up a pictur

122 Here we review the increasingly large role informatics-driven approaches are playing in such effort

123 Rapid developments in informatics, emphases on large sample collection for gen

124 In this study we found, using lipid mediator informatics employing liquid chromatography-tandem mass

125 comparative questions is an early version of informatics-enabled CER familiar to oncologists.

126 An updated version of informatics-enabled CER relies on EHR-derived structured

127 ChemBank is a public, web-based informatics environment developed through a collaboratio

128 atory networks (GRNs) and thereby provide an informatics environment to study the effects of interven

129 ons on potential solutions based on bioimage informatics, especially automated image computing.

130 allowing biomedical scientists with minimal informatics expertise to remotely call, view, and furthe

131 lp readers, including those without bioimage informatics expertise, understand the capabilities, appr

132 by individuals or groups that lack clinical informatics expertise.

133 erstanding of the mammalian genome thanks to informatics, expression profiling and sequencing of the

134 ll status of available software for bioimage informatics, focusing on open-source options.

135 In the paradigm of materials informatics for accelerated materials discovery, the cho

136 The i2b2 Center (Informatics for Integrating Biology and the Bedside) has

137 fragment mapping based on the Protein-Ligand Informatics force field (PLIff).

138 This paper introduces the protein-ligand informatics "force field", PLIff, which begins to addres

139 We constructed and applied an open source informatic framework called Cistematic in an effort to p

140 The entire biomedical imaging informatics framework consists of cell detection, segmen

141 The cancer Biomedical Informatics Grid (caBIG(R)) Life Science BAM (LS BAM) pr

142 ctor Machine (PUGSVM) is a cancer Biomedical Informatics Grid (caBIG) analytical tool for multiclass

143 l-scale effort, called the cancer Biomedical Informatics Grid (caBIGtrade mark), to develop a federat

144 twork (DDN) is a caBIG(R) (cancer Biomedical Informatics Grid) analytical tool for detecting and visu

145 the various nomenclature committees, the HLA Informatics Group and in collaboration with the European

146 Through the work of the HLA Informatics Group and in collaboration with the European

147 Through the work of the HLA Informatics Group and in collaboration with the European

148 Through the work of the HLA Informatics Group and in collaboration with the European

149 Here we develop an informatics-guided ab initio approach to accelerate the

150 f metabolite databases, and progress in (bio)informatics has made agnostic approaches more attractive

151 ng-based analyses, other areas of biological informatics have not yet adopted them.

152 Advances in DNA sequencing and informatics have revolutionised biology over the past fo

153 ter-based image analysis system (Imaging and Informatics in ROP [i-ROP]) was developed using a set of

154 Part 2 will focus on the impact of informatics in the radiology reading room and on recent

155 control the activity of the enhancers using informatics, in vivo occupancy by TFs that regulate cort

156 The degree of informatic independence between the physical properties

157 as open source for download at http://omics.informatics.indiana.edu/GeneStitch

158 load at the RAPSearch2 website: http://omics.informatics.indiana.edu/mg/RAPSearch2/.

159 load at the RAPSearch2 website: http://omics.informatics.indiana.edu/mg/RAPSearch2/.

160 In summary, this novel web server (cancer.informatics.indiana.edu/mmia) will provide life science

161 an can be freely downloaded at http://darwin.informatics.indiana.edu/MultiGlycan/.

162 or the structural kernel is available at www.informatics.indiana.edu/predrag/.

163 The source code is available on http://bio.informatics.indiana.edu/projects/arcs and http://goldeng

164 The development of biological informatics infrastructure capable of supporting growing

165 it is accompanied by an equal investment in informatics infrastructure.

166 Informatic interrogation of mRNA sequence databases reve

167 evaluate the impact of incorporating health informatics into the management of SAB via a pharmacist-

168 Informatics is a broad field encompassing artificial int

169 Imaging informatics is a distinct subspecialty of radiology that

170 Biodiversity informatics is an emerging field that applies informatio

171 Computational vaccinology or vaccine informatics is an interdisciplinary field that addresses

172 A major challenge facing biodiversity informatics is integrating data stored in widely distrib

173 Clinical pathway informatics is regarded as an efficient way to solve a s

174 blication page of the Web site http://sparks.informatics.iupui.edu.

175 ilable as a SPARKS-X server at http://sparks.informatics.iupui.edu/

176 line database we developed, PAGED http://bio.informatics.iupui.edu/PAGED is by far the most comprehen

177 ls (SPOT) package available at http://sparks.informatics.iupui.edu/spot

178 D is available through the MGI web site (www.informatics.jax.org), or directly at www.informatics.jax

179 MGD is web accessible at http://www.informatics.jax.org.

180 lable through the MGI web site at http://www.informatics.jax.org/ or directly at http://www.informati

181 The Gene Expression Database (GXD; www.informatics.jax.org/expression.shtml) is an extensive an

182 www.informatics.jax.org), or directly at www.informatics.jax.org/expression.shtml.

183 formatics.jax.org/ or directly at http://www.informatics.jax.org/menus/expression_menu.shtml.

184 semantic similarity, available under http://informatics.med.yale.edu/ytex.web/.

185 We have devised a chemocentric informatics methodology for drug discovery integrating i

186 Further, informatics methods are presented to confidently filter

187 egration with the other data in Mouse Genome Informatics (MGI) and interconnections with other databa

188 genetic and phenotypic data in Mouse Genome Informatics (MGI) and made readily accessible to many ty

189 GD) is a major component of the Mouse Genome Informatics (MGI) database resource and serves as the pr

190 Integration with the other Mouse Genome Informatics (MGI) databases places the gene expression i

191 are formally represented in the Mouse Genome Informatics (MGI) resource.

192 MGD is a major component of the Mouse Genome Informatics (MGI) resource.

193 through integration with other Mouse Genome Informatics (MGI) resources and interconnections with ma

194 ase and three data types from Mouse Genomics Informatics (MGI).

195 ; National Center for Integrative Biomedical Informatics (NCIBI) and is publicly available at: http:/

196 e National Center for Integrative Biomedical Informatics (NCIBI) and is publicly available at: http:/

197 d National Center for Integrative Biomedical Informatics (NCIBI) suite of tools, freely available at

198 to biologist and therapist to get real time informatics needed to evaluate death process, diseases p

199 tool for AD management program to obtain bio-informatics needed to optimize therapeutics for neurodeg

200 f the challenges in genomics derive from the informatics needed to store and analyze the raw sequenci

201 Thus, a core question in the informatics of drug design is what type of molecular sim

202 ntent super-resolution nanoscopy and imaging informatics of the nuclear organization of epi-marks.

203 hardware, expensive apparatus, and advanced informatics or can only be used in single experimental m

204 ed to explore the role of healthcare system, informatics, organizational and practice-related factors

205 A number of informatics packages have been developed for this purpos

206 em, focusing on 4 major domains: science and informatics, patient-clinician partnerships, incentives,

207 enes, which were processed with an automated informatics pipeline and manually annotated.

208 e light sheet instrumentation and an imaging informatics pipeline of five steps to achieve mapping of

209 tilizing an in-house assembly and analytical informatics pipeline.

210 of 334,652 SNVs that were consistent between informatics pipelines yet inconsistent with haplotype tr

211 ne (xcmsonline.scripps.edu) is a cloud-based informatic platform designed to process and visualize ma

212 uestionnaires on atopy were acquired through informatics platform (AllergyCARD).

213 The Meningococcus Genome Informatics Platform (MGIP) is a suite of computational

214 Pathology Image Informatics Platform (PIIP) is an NCI/NIH sponsored proj

215 s the most comprehensive data repository and informatics platform related to the laboratory rat, one

216 rain Institute with access to Brain-CODE, an informatics platform that hosts a multitude of biologica

217 r advanced imaging tools and clinical trials informatics platforms.

218 The Mitochondrial tRNA Informatics Predictor (MitoTIP) is available through MIT

219 In this paper, we provide an informatics primer on farm animal bioinformatics and gen

220 Understanding informatics principles is important because these princi

221 of time series is beneficial for biomedical informatics problems such including, but not limited to,

222 resource created by the Genetic Resource and Informatics Program at the Oregon National Primate Resea

223 is is a first report, using our MotifModeler informatics program, to simultaneously identify transcri

224 unity effort that combines modern bioimaging informatics, recent leaps in labeling and microscopy, an

225 While mainstream biomedical informatics research focuses on developing more accurate

226 d noncoding RNAs absent from The Arabidopsis Informatics Resource 10 build.

227 vidual investigator's laboratories and major informatics resource centers such as Ensembl, UniProt an

228 vidual investigator's laboratories and major informatics resource centers, such as Ensembl, UniProt a

229 idual investigators and downloads from major informatics resource centers.

230 are driving the development of shared online informatics resources by gaining access to data where it

231 Web 2.0 and advanced informatics resources will be part of physician lifelong

232 on and sustainability of international mouse informatics resources), with a remit to assess the techn

233 the rapidly growing capabilities of several informatics resources, genomic data from model cereals a

234 Based on the informatics results, we analyzed the respiratory functio

235 experimental miRNA researchers, but also for informatics scientists developing the next-generation mi

236 pment of a chemoinformatic library-based and informatic search strategy for natural products (iSNAP)

237 cted mutagenesis, and this motif was used in informatic searches to reveal a previously undescribed S

238 hly curated, community-oriented database and informatics service to researchers focused on the crop p

239 Although the procedure assumes basic informatics skills, these tools assume little to no back

240 ation studies, there is currently a need for informatics solutions that facilitate the integration of

241 wn vision for future development of bioimage informatics solutions.

242 re supporting data sharing, data management, informatics, statistical methodology, and research ethic

243 In recent years, informatics studies have predicted several new ways in w

244 Informatics studies suggest that related catalytic domai

245 LIMITATION: This was a 1-year informatics study conducted at a single hospital subspec

246 to invest significant resources into custom informatics support for genome sequencing projects remai

247 ) is a dedicated database and structural bio-informatics system for distance based protein modeling.

248 Sipros/ProRata is a versatile informatics system that enables identification and quant

249 computational challenge, requiring powerful informatics systems and bioinformatics expertise.

250 ta may be kept securely under governance and informatics systems that are fit-for-purpose and appropr

251 hat an opportunity exists to employ hospital informatics systems to improve the prescription of antib

252 odology and the development of interoperable informatics systems, which has been recognized by the Na

253 and improve patient safety and quality, and informatics systems.

254 We developed an informatic technique that identifies statistically signi

255 Current informatic techniques for processing raw chromatography/

256 l modelling, diagnostic, communications, and informatics technologies can identify and report hithert

257 addressed is how human-machine interface and informatics technologies could combine to transform the

258 entary and potentially transformative health informatics technology for research and patient care.

259 Advances in image acquisition and informatics technology have led to organism-scale spatio

260 conclude by reviewing advances in biomedical informatics that will eventually allow the human proteom

261 nalysis, the use of social media and medical informatics that will further advance clinical medicine

262 Modern biomedical informatics theory and practice has demonstrated the dis

263 systems (PACS) are a major focus of imaging informatics, there are many other ways in which technolo

264 In addition, the advancement of informatics to allow the intersection of multiple comple

265 These findings were shown by informatics to be relevant to the head morphogenesis of

266 ervention comprising professional education, informatics to facilitate review, and financial incentiv

267 Here, we call for a more formal waste informatics to organize and standardize waste management

268 ssical mechanics simulations, and structural informatics to understand this aspect of ion partitionin

269 After validation, the informatics toolkit was used to populate an exposure rep

270 ntal spectral data, predictive modeling, and informatic tools enables more efficient, reliable, and t

271 Newly developed image-based informatics tools allow global genome-scale structural a

272 New informatics tools are needed to model the experimental a

273 Antibody informatics tools can help improve our understanding of

274 Advanced informatics tools can identify phenotypically relevant d

275 nts Toolkit (CRAVAT) is an evolving suite of informatics tools for mutation interpretation that inclu

276 resources, but there is a critical need for informatics tools in individual laboratories to help man

277 ir interplay break inversion symmetry, while informatics tools learn from available data to select ca

278 While existing informatics tools provide efficient bulk variant annotat

279 nstrate the need for advanced cancer imaging informatics tools that can help ensure protocol-complian

280 ubstantial efforts have been made to develop informatics tools to alleviate MS data interpretation.

281 We used cell-based reporter methods and informatics tools to efficiently screen a large collecti

282 sed functional signatures with complementary informatics tools to examine drug combinations.

283 hput screening (qHTS) approach combined with informatics tools to screen the Tox21 library of 10,000

284 free text concepts identified using clinical informatics tools, disease labels can be assigned with a

285 seeking to ensure that there are appropriate informatics tools, systems and databases available to ma

286 Here, using newly developed informatics tools, we tracked changes in DNA copy number

287 s therefore a central step toward developing informatics tools, which can support the clinician in th

288 digital image archives by using open-source informatics tools.

289 functionally validated data set to calibrate informatics tools.

290 pertise and familiarity with a wide range of informatics tools.

291 les, partly due to the large availability of informatics tools.

292 sis in life sciences, as researchers without informatics training attempt to perform computation-depe

293 The randomized clinical Genetic Informatics Trial (GIFT) of Warfarin to Prevent Deep Vei

294 server TRFolder-W is available at http://rna-informatics.uga.edu/?f=software&p=TRFolder-w.

295 ers) from the Scottish Primary Care Clinical Informatics Unit Research (PCCIU-R) database were descri

296 g of the nature and clinical significance of informatics variability and adopting strategies to reduc

297 ining nanoscopy with epi-mark textural image informatics, we developed a novel approach, termed EDICT

298 MTB is accessed via the Mouse Genome Informatics web site.

299 g value imputation steps to the conventional informatic workflow.

300 three critical points of failure in current informatic workflows: compound specific drift, integrati