ライフサイエンスコーパス: inherently

1 Thus, conventional cancer therapy is inherently a double-edged sword.

2 mpact mode-locked THz laser, which itself is inherently a frequency comb, has yet to be achieved with

3 Obesity is inherently a metabolic disease, and metabolic profiling

4 Human touch is an inherently active sense: to estimate an object's shape h

5 In addition, the organelles themselves are inherently active, and it is not clear how the active, e

6 Challenges, the validation of the methods is inherently addressed.

7 ed inequities (exclusivity of living donors, inherently advantaging self-advocates, navigating langua

8 However, the universal MSP is inherently aerobic due to a requirement of molecular oxy

9 RT promoter (TERT-p) mutations are common in inherently aggressive cutaneous conventional melanoma, w

10 results in highly dynamic crystal lattices, inherently allowing rapid ion exchange at the solid-vapo

11 Nod2-deficient (Nod2(-/-)) mice had an inherently altered skin microbiome compared with wild-ty

12 The source of visual motion is inherently ambiguous such that movement of objects in th

13 Inference of sequence homology is inherently an evolutionary question, dependent upon evol

14 Atherosclerosis is inherently an inflammatory process that is strongly affe

15 ass spectrometry indicated that caspase-6 is inherently and dramatically more conformationally dynami

16 ng low and high expression variability, both inherently, and in response to environmental exposures.

17 Resilience can inherently assist individuals to diminish adverse psycho

18 and this carbon uptake for photosynthesis is inherently associated with a large efflux of water vapor

19 oining while suppressing genomic instability inherently associated with DSBs are yet to be fully eluc

20 Controlling disease progression is inherently associated with the ability to predict possib

21 on the regulation of B cells expressing the inherently autoreactive VH4-34 H chain (identified by th

22 e for organometallic chemistry that provides inherently better results when applied to substrates con

23 demonstrating that the Cin8 head domains are inherently bidirectional, but control over directionalit

24 he exquisite nanoscale shape control of this inherently biocompatible material is combined with the p

25 d ions for example in the radiation belts is inherently broadband, but this is a feature hard to mimi

26 of wide-field fluorescence microscopy, it is inherently capable of multicolor imaging and optical sec

27 Studying metabolism is inherently challenging due to metabolites' reactivity, s

28 kes scaling of computational imaging systems inherently challenging for electrically large, coherent

29 nts in the first part of the 20th century to inherently challenging human studies.

30 chers to only scratching the surface of this inherently challenging subject.

31 Single bonds between carbon atoms are inherently challenging to activate using transition meta

32 oselective interaction occurring between the inherently chiral AuNPs and enantiomers in the first fil

33 the first example of a meta-functionalized, inherently chiral calix[6]arene derivative.

34 e, resulting in the formation of isomers and inherently chiral macrocycles due to inhibited rotation.

35 as amino acids, sugars and nucleotides, are inherently chiral.

36 Some proteins, such as HA and M2, inherently cocluster within the membrane, although M2 is

37 Accessory pathogens, while inherently commensal in a particular microenvironment, n

38 resent a new phase of industrialization with inherently complex and challenging trade-offs.

39 Diffusion of particles in curved surfaces is inherently complex compared with diffusion in a flat mem

40 s new uses for existing drugs highlights the inherently complex nature of cancer biology.

41 "Phenotype" is an inherently complex notion that we describe in the concep

42 n has proven challenging, due in part to the inherently complex stimulus domain of dynamic biological

43 As environments in nature are inherently complex these findings help explain why sex i

44 Because systems with many components are inherently complicated, one might assume that the chance

45 ressures, flexible imitation of models might inherently confer secondary benefits to mimics.

46 ds using natural products (plant-based) will inherently confer to new products with less calories, fa

47 Numerosity is inherently confounded by related stimulus attributes suc

48 of self-motion and object motion, which are inherently confounded in the retinal image.

49 ystems like carbon nanostructures, which are inherently constituted by large conjugated pi-systems.

50 demonstrate that activities of Nbr and Hen1 inherently contribute to TE silencing and age-dependent

51 orms of plasticity, such as learning, may be inherently costly.

52 Protein biosynthesis is inherently coupled to cotranslational protein folding.

53 KLF during late stages of differentiation is inherently critical for enucleation of erythroid precurs

54 Free-standing graphene is inherently crumpled in the out-of-plane direction due to

55 lacks an envelope, it has been thought to be inherently cytolytic, wherein CVB can escape from the in

56 ily selected sets of physical properties are inherently deficient.

57 ctions that will enable progressing from the inherently descriptive nature of localization and -omics

58 However, as inherently destructive enzymes, their activity must be c

59 tailed structural information on amyloids is inherently difficult because of their insoluble, non-cry

60 h lacks a newly formed bond and is therefore inherently difficult to detect.

61 These applications of MICP are inherently difficult to monitor nondestructively in time

62 some nanomaterials are composed of elements inherently difficult to quantify by quadrupole ICP-MS du

63 ocesses in the natural environment yet it is inherently difficult.

64 e NMR characterization of proteins which are inherently dilute, such as membrane proteins.

65 application is for imaging signals that are inherently dim and undetectable using standard microscop

66 applies to both industry and academia as an inherently direct and sustainable strategy to induce chi

67 GWD deposits are inherently discontinuous and stratigraphically complex,

68 Many everyday estimation tasks have an inherently discrete nature, whether the task is counting

69 The reservoir model inherently displayed a dynamic form of mixed selectivity

70 Quantum systems are inherently dissipation-less, making them excellent candi

71 tions, indicating that human P450 17A1 is an inherently distributive enzyme but that some processivit

72 hanism through which the brain may translate inherently diverse social cues into coherent categorizat

73 bstitution-inert compounds a unique class of inherently dual-action anti-cancer agents.

74 previously limited, at least in part, by the inherently dynamic nature of emerging nascent chains, wh

75 ucture of the Escherichia coli chromosome is inherently dynamic over the duration of the cell cycle.

76 The brain is an inherently dynamic system, and executive cognition requi

77 ny biological process, cancer development is inherently dynamic.

78 All biological processes are inherently dynamic.

79 However, drugs are not inherently effective; the benefit of a drug is directly

80 h, thereby the depth of signal generation is inherently encoded in the spectra.

81 Currently, most in vitro RT activity assays, inherently end-point measurements, are based on the dete

82 targets of selection; yet these targets are inherently enriched for genes of large target size and m

83 Genomic imprinting, an inherently epigenetic phenomenon defined by parent of or

84 These polymerases are inherently error prone, owing to their lack of a proofre

85 , and confirms the (betaalpha)8 barrel as an inherently evolvable protein scaffold.

86 Studying black Swiss mice, which inherently exhibit proclivity for reward seeking and ris

87 easuring a linear relationship, which should inherently exist between mobility size and one-third pow

88 cal structures within the tissues, which may inherently exist in normal tissues or may be formed by i

89 Many environmental pollutants inherently exist in their anionic forms and are therefor

90 While polarization inherently exists in ferroelectric barium titanate (BaTi

91 nsions, the material properties required are inherently extremely difficult to achieve.

92 Because RNA is inherently flexible, it assumes a variety of conformatio

93 kable subjective disappearances, but are not inherently fluctuations in stimulus visibility.

94 well suited for pragmatic trials because of inherently frequent and predictable patient encounters,

95 Tailored synthesis of inherently functional building blocks can generate frame

96 The power density of the ALD modified and inherently functional commercial cells exhibited enhance

97 ortex that performed HMC inference, and thus inherently gave rise to oscillations and transients.

98 f nervous system function and development is inherently global, since all components eventually influ

99 ssertion that differential susceptibility is inherently grounded within processes of biological moder

100 d not only reflects organ function, but also inherently hardwires networks of communication between s

101 for valorization of polymeric lignin that is inherently heterogeneous and recalcitrant.

102 and therefore that the learning problem was inherently hierarchical.

103 s were greater than label values, because of inherently high 5-MTHF occurring in samples.

104 to support this rapid refilling owing to an inherently high activation energy barrier.

105 ic products from a variety of sources, is of inherently high complexity in composition, phase, and ph

106 The inherently high cross-selectivity of the system obviates

107 tal and powder PL decay curves of 1 suggests inherently high defect tolerance.

108 The inherently high reactivity of RSSH to H-atom transfer is

109 on capacities of TPrA and combines LAMP with inherently high sensitivity of the ECL technique, to fac

110 ninfected BN rat, the uninfected LEW rat has inherently higher transcript levels of cytochrome enzyme

111 pproach has been developed to surface modify inherently hydrophobic Kapton HN substrates to allow for

112 These particles are inherently hygroscopic, that is, they take-up moisture f

113 es at opposite frequencies and momenta to be inherently identical.

114 ous and exogenous retroviruses is considered inherently immunosuppressive.

115 es of enterococci can include those that are inherently incompatible with native flora, highlighting

116 DKO mice display an inherently increased capacity to burn fat and suppress d

117 o distribute over multiple processors but is inherently inefficient.

118 Regeneration of human cartilage is inherently inefficient; an abundant autologous source, s

119 particular, as a solid-state material which inherently integrates the photochromic switch and photos

120 Communication is an inherently interactive process that weaves together the

121 In behavior, action and perception are inherently interdependent.

122 Neuroscience is inherently interdisciplinary in its quest to explain the

123 Evolution and development are two inherently intertwined processes.

124 (ALDLT) is not commonly performed due to its inherently intricate surgical technique and immunologica

125 Multicellularity inherently involves a number of cooperative behaviors th

126 ate understanding of biomolecular mechanisms inherently involves our ability to model them.

127 Social interaction inherently involves the subjective evaluation of cues sa

128 ect carbon or nitrogen dimensions with their inherently large chemical shift dispersion lies in the u

129 es in the pursuit of magnetic materials with inherently larger magnetic moments.

130 Hence, molecular crystallization is inherently less controllable than framework crystallizat

131 Hence, empirical rules are inherently less reliable for engineering the structures

132 ant to understand because their supplies are inherently less responsive to market balancing forces, i

133 d lines but have an epigenetic state that is inherently less stable within the A. thaliana species.

134 tified by high-throughput screening are thus inherently likely to be deimmunized.

135 lenging the assertion that such screening is inherently limited by batch effects.

136 These approaches are still inherently limited by the bacterial growth rate.

137 Here, sensitivity to magnetic noise is inherently limited by the flat slope of the so-called cl

138 phenomenon in humans (EEG/MEG), however, are inherently limited by their spatial resolution and there

139 fit of "precision targeting" of mutations is inherently limited by this counterproductive effect.

140 g cells typically used in cytometry that are inherently limited to low flow rates.

141 Natural history data are inherently limited, and a randomized clinical trial is n

142 Many are also not inherently limited, so that it becomes difficult to even

143 que methodology and information, but each is inherently limited.

144 ependent control of quiescence exit kinetics inherently limits LT-HSC divisions and preserves the HSC

145 h knowledge in premalignant neoplasia, which inherently limits the potential to develop precision pre

146 ation of the Central Basin in Spitsbergen is inherently linked to changes in regional plate motions,

147 Here, we discuss how the naive state is inherently linked to preimplantation epiblast identity i

148 ian statistics and dynamic heterogeneity are inherently linked to the slow-active remodelling of the

149 cause inference about the death mechanism is inherently linked to the speed of damage recovery.

150 r nature, these two signaling components are inherently linked.

151 ration and hippocampal binding processes are inherently linked.

152 Nonetheless, attempts to improve its inherently low activity are rarely based on rational app

153 lic acid in the raw flour was reported to be inherently low compared to bread; the concentration incr

154 Major drawbacks are, however, an inherently low electrical conductivity and a limited hol

155 MCF-7 tumors, with inherently low GLS activity compared with TNBC, displaye

156 an upwelling system that already experiences inherently low pH conditions, the California Current.

157 g for a needle in a haystack" because of the inherently low rate of spontaneous emission of character

158 g resistance in pests with mobile larvae and inherently low susceptibility to the toxins in Bt crops.

159 The device is inherently low-cost and the power consumption is minimal

160 based on all-fibre technology, our system is inherently low-cost, lightweight and may lead to the dev

161 Larger analytes, with inherently lower diffusivities, suffer from lengthy resp

162 ffects are seen in poliovirus polymerase, an inherently lower-fidelity enzyme where analogous mutatio

163 image fusion in the context of combining the inherently lower-resolution chemical images obtained usi

164 is typically accomplished through the use of inherently magnetic materials with large magnetic permea

165 he angiotensin II receptor type 1 (AT1 R) is inherently mechanosensitive and initiates this signallin

166 Despite such inherently minimal energetic differences between the 12

167 als, the wavefunctions of such electrons are inherently modified.

168 Because this approach is inherently modular and places minimal requirements on th

169 sed on redox active colloids (RACs) that are inherently modular in their design and overcome challeng

170 a failed primary PR selects for RDs that are inherently more difficult to reattach.

171 r drug candidates than peptides due to their inherently more favorable pharmacokinetic properties.

172 lants make arbuscular mycorrhizal (AM) fungi inherently more nitrogen (N) limited and less phosphorus

173 rate control, in which the substrate has one inherently more reactive C-H bond or contains a directin

174 ach, automated classification techniques are inherently more reproducible and efficient.

175 These phenomenological studies reveal that inherently motile cardiopharyngeal progenitors are chann

176 itional carrier-based nanomedicines that are inherently multicomponent systems, an OCN does not requi

177 difficulty stems more significantly from the inherently multiconfigurational character of the ground

178 community remain challenging because of the inherently multidisciplinary expertise required to condu

179 Although C auris is inherently multidrug resistant, other strains typically

180 t IRF-1 enforces long-term suppression of an inherently mutagenic stage of B cell differentiation tha

181 oad, polyclonal germinal center reaction, an inherently mutagenic stage of B cell differentiation tha

182 llic nanoshells or nanoparticles, which have inherently narrow absorption bandwidth.

183 n and over expression experiments, which are inherently noisy and suffer from missing values.

184 a method developed to estimate SLP from the inherently non-adiabatic measurements, where we identify

185 ch the collective spatiotemporal dynamics in inherently non-equilibrium systems.

186 any life history and behavioral traits, have inherently nonnormal distributions.

187 on extrinsic immune-selective pressure or is inherently orchestrated by oncogenic pathways is unresol

188 Viral replication in eukaryotes is a process inherently organized in both space and time.

189 imentally demonstrated, which stems from the inherently packaged structure of FO-TEG.

190 ever, existing SAGA methods cannot integrate inherently pairwise chromatin conformation data.

191 h the original picture of amyloid fibrils as inherently pathological structures.

192 These results suggest that inherently periodic slow-slip events result in periodic

193 ated with absorbing a portion of its energy, inherently perturbing the measurement and creating refle

194 racterize a different type of crease that is inherently plastic and is formed by the propagation of a

195 majority of MPER-specific antibodies are not inherently polyspecific and/or autoreactive, suggesting

196 applicability of NMR and MRI are limited by inherently poor sensitivity and insufficient nuclear spi

197 in several additional cancer cell lines with inherently poor uptake resulted in improved activity of

198 ndings establish that adult hippocampal NSCs inherently possess multilineage potential but that Drosh

199 not yet been examined in plants that do not inherently possess p-coumarates on their lignins.

200 minent theoretical view is that the brain is inherently predictive [1, 2] and that prediction helps d

201 ic surfaces, and thus, the resulting schemes inherently prefer cases where the water drops move at a

202 trategies dealing with a number of artifacts inherently present in data from ultrafast optical experi

203 lex structure, yet nanoscale nonuniformities inherently present in polyamide layer may reduce selecti

204 ich would make an etiologic nosologic system inherently problematic.

205 cing targets a known genetic region and thus inherently produces reads highly anticipated to have cer

206 nted as an alternate approach, as waveguides inherently provide a large density of channels for photo

207 ct ratio (AR) dependence of LSPR band maxima inherently provides an ideal multiplex mechanism.

208 Many of the available drugs were inherently quite toxic when used as continuous treatment

209 le, the infamous Tuskegee syphilis study was inherently racist and how other experiments exploited me

210 we show that initiation and termination are inherently random events.

211 ization of proline 47 (Pro47) within p53, an inherently rare molecular event, was required for BAX ac

212 nt non-enzymatic reactions can occur through inherently reactive bacterial metabolites.

213 ells; however, less is known about how it is inherently regulated in comparison to its closest homolo

214 ynthesis, morphology, and device physics are inherently related in explaining the measured device out

215 neral density is poorly understood but it is inherently related to increasing age.

216 nd coefficient of thermal expansion that are inherently related to terminal chemical groups that limi

217 cs and indicate that dynamical heterogeneity inherently relates to the fragility of glass-forming mat

218 Thus, perception inherently relies on solving the "causal inference probl

219 ased on the reintroduction of photoreceptors inherently rely on the ability of the remaining retinal

220 isorders since the platelet-CTC interactions inherently rely on the blood coagulation cascade includi

221 means that any error in the reference method inherently represents at least a 2-fold difference.

222 Unfortunately, this method inherently requires fluorescent labeling which has sever

223 hat suppressing ST6Gal-I activity sensitizes inherently resistant cells to gemcitabine.

224 However, colorectal cancer (CRC) cells are inherently resistant to anthracyclines which at higher d

225 the vegetation, either as the vegetation is inherently resistant to change, management prevents incr

226 dulloblastoma driven by a mutant SMO that is inherently resistant to existing SMO inhibitors, prolong

227 ty barrier that makes Gram-negative bacteria inherently resistant to many antibiotics.

228 CUT&RUN is simple to perform and is inherently robust, with extremely low backgrounds requir

229 uld include alternative chemistries that are inherently safer to operate than nonaqueous lithium-base

230 are formed by structural viral proteins that inherently self-assemble when expressed in a host cell.

231 It is shown that photonic sintering is an inherently self-damping process, i.e., the progress of d

232 Indeed, B cells and plasma cells were inherently sensitive to Rab7 gene knockout or Rab7 activ

233 can exhibit a rich set of dynamics that are inherently sensitive to their initial conditions.

234 whether this relationship stems from having inherently short leukocyte TL (LTL) at birth or a faster

235 mination offers a strategy to circumvent the inherently short-lived excited states of 3d metal comple

236 Magnetic resonance imaging is an inherently signal-to-noise-starved technique that limits

237 near input-output relationship have remained inherently single-channel devices (just like their elect

238 have rendered tooth formation and incubation inherently slow in other dinosaur lineages and basal bir

239 ular bony surfaces of the body, comprises an inherently "smart" material that gives hard bones added

240 es.SIGNIFICANCE STATEMENT Bilingualism is an inherently social phenomenon, interactional context full

241 t they may sometimes defer to informants for inherently social reasons.

242 Inherently solvent and ligand-free, nonthermal plasmas o

243 ervation effectiveness and private costs are inherently spatial; varying the location of conservation

244 urthermore, we find that marsh responses are inherently spatially dependent, and cannot be adequately

245 pedance derived electroanalytical assays are inherently spectroscopic (frequency resolved) and potent

246 ests that soil organic matter is composed of inherently stable and chemically unique compounds.

247 lient cue for reorientation because it is an inherently stable aspect of the environment.

248 location in the actinide series between the inherently stable half-filled 5f(7) configuration of cur

249 g conditions, the shear-NO process may i) be inherently stable, ii) oscillate spontaneously in respon

250 By implementing an inherently stable, reconfigurable spatial-light-modulato

251 stantially high absorption cross-section and inherently step-like absorption profile, compared to tho

252 ide individual cells, expression of genes is inherently stochastic and manifests as cell-to-cell vari

253 efore, stable gut diversity may be driven by inherently stochastic processes, which has important imp

254 sorder - structural and energetic - and from inherently strong electron-vibration couplings.

255 conceive a novel architecture that exploits inherently strong evanescent THz field arising within th

256 y (resulting in higher capsid pressure) have inherently stronger capsid structures, preventing sponta

257 te whether viral communities in wildlife are inherently structured (inferring predictability) by look

258 urn models suggest that risk and benefit are inherently subjective, and risk taking is best understoo

259 ator dependent, whereas visual assessment is inherently subjective.

260 However, their results inherently support that the Southern East Pacific Rise i

261 This finding suggests that these inherently susceptible species possess latent defenses t

262 haplotypes by transmission when possible and inherently takes into account the linkage disequilibrium

263 The inherently three-dimensional transition from bulk-turbul

264 ic phase within Symbiodinium life history is inherently tied to a more cryptic free-living (ex hospit

265 These species are inherently tied to aerosol pH, which is a key parameter

266 2 Growth and metabolism of cyanobacteria are inherently tied to the diurnal rhythm of light availabil

267 s to identify candidate fragments, which are inherently time-consuming and often hinder the possibili

268 ringent dependence of such strategies on the inherently toxic IL-2 has raised safety concerns for pat

269 ions have been particularly limited by their inherently transient nature.

270 Mesenchymal stromal cells (MSCs) are inherently tumor homing and can be isolated, expanded, a

271 erimentally advantageous platform due to the inherently tunable nature of surface plasmon excitation

272 The conventional optical microscope is an inherently two-dimensional (2D) imaging tool.

273 istant to PPI-based intervention or PPIs are inherently unable to suppress acid GER.

274 nty analysis via Monte Carlo simulations are inherently uncertain due to their statistical nature and

275 nscriptional machinery and core promoter are inherently unidirectional and that reverse-oriented tran

276 ngly increased provisioning services in more inherently unproductive grasslands.

277 common means of air disinfection, but it is inherently unreliable and of limited use in cold climate

278 It makes live vaccines and engineered cells inherently unreliable and unpredictable, and therefore p

279 radical aromatic substitution reactions are inherently unselective.

280 Toroidal droplets are inherently unstable due to surface tension.

281 llenged by the fact that these particles are inherently unstable in serum becaue of interactions with

282 ures to be generated from molecules that are inherently unstable in solution and in the solid state.

283 d receptor ligand-binding domains (LBDs) are inherently unstable, and their crystallization requires

284 Many animal bodies are inherently unstable, necessitating corrective locomotion

285 However, this ongoing plasticity is also inherently unstable, potentially leading to aberrant lev

286 ndly, high energy-density materials, but are inherently unstable.

287 vely charged (25/76 amino acid residues) and inherently unstructured in solution.

288 a further step such frequency changes proved inherently useful for examining the binding properties o

289 ts a solution to the problem of transporting inherently variable substrates such as polypeptides, and

290 This reaction is inherently versatile, allowing for variations of substit

291 otic filaments indicate that biopolymers are inherently very sensitive to the coupling between twist,

292 constituent parts of a quantum computer are inherently vulnerable to errors.

293 However, permittivity modulation is inherently weak and accompanied by loss due to carrier i

294 However, Raman signals are inherently weak and so far have been limited in spatial

295 nic interface to sense chiral molecules with inherently weak circular dichroism at visible and near-i

296 emporal resolution is challenging due to the inherently weak nonlinear optical signals generated in s

297 The inherently weak O-heteroatom bond in the oxidant enables

298 Owing to the inherently weak spin-orbit coupling (SOC) of OSECs, thei

299 nonlinear responses in natural materials are inherently weak.

300 The resulting small devices will be inherently well suited for multiplexed and parallel dete