ライフサイエンスコーパス: inheritable

1 pproximately 5% to 10% of breast cancers are inheritable.

2 hat chemically modify nucleosomes leading to inheritable activation or repression of pertinent genes

3 characterize platelets from patients with an inheritable alpha-granule defect, demonstrating a role f

4 This system represents an inheritable and adaptable immune system that is mediated

5 ed that the proposed dual-isotope marking is inheritable and can be detected after both long-term and

6 ional properties of p73 can be altered in an inheritable and cell-specific fashion independent of tra

7 molecular basis of prostate cancer includes inheritable and somatic genetic changes (tumour suppress

8 rview of the many pathways, both genetically inheritable and sporadic, that may lead to the premature

9 Through the study of uncommon inheritable arrhythmia syndromes, including the long QT

10 ), the most common of the potentially lethal inheritable arrhythmias, with specific focus on the gene

11 ave seen tremendous progress in the field of inheritable arrhythmias.

12 y ranging from 24 to 86%, and mutations were inheritable at high frequencies (18-100%).

13 We identified 67 and 376 inheritable autosomal random monoallelically expressed g

14 germline mutations account for up to 30% of inheritable breast cancers and are the most commonly ass

15 rapeutic interventions for both acquired and inheritable cardiac diseases.

16 as elucidated the pathophysiology of several inheritable cardiovascular disorders and will ultimately

17 ology of fragile X syndrome, the most common inheritable cause of intellectual disability.

18 A non-mutational mechanisms for generating inheritable chlorophyll deficiency has implications for

19 While CNVs are naturally occurring and inheritable, CNAs are acquired somatic alterations most

20 needs to be tested further, the discovery of inheritable CpNpG methylation in the human genome may ha

21 We have studied two inheritable cysteine mutants of cyclic nucleotide-gated

22 Its inheritable D244G mutation causes a myopathy with vacuol

23 By co-injecting two GoldyTALEN pairs, inheritable deletions of a large genomic fragment up to

24 n overload disease, is the most common known inheritable disease.

25 ments are associated with carcinogenesis and inheritable diseases.

26 ments are associated with carcinogenesis and inheritable diseases.

27 form of Rubinstein-Taybi syndrome (RTS), an inheritable disorder caused by mutations in the gene enc

28 and nevoid basal cell carcinoma syndrome, an inheritable disorder causing a predisposition to cancer

29 cellular positional identity by establishing inheritable domains of repressive and active chromatin w

30 Inheritable epigenetic changes ("epimutations") with eff

31 ere may also be present preexisting unstably inheritable epigenetic trends leading to cellular varieg

32 Our studies have also shown that inheritable factors strongly influence the disease susce

33 Studies of dominant inheritable familial AD support the hypothesis that APP

34 ) receptor (alpha1beta2gamma2L(K289M)) in an inheritable form of epilepsy (GEFS+, generalized epileps

35 ular podocytes and shown to be mutated in an inheritable form of glomerulosclerosis is alpha-actinin-

36 Fragile X Syndrome (FXS) is the most common inheritable form of intellectual impairment, including a

37 g of numerous genetic mutations that lead to inheritable forms of distal renal tubular acidosis (dRTA

38 environment, seem more likely to be separate inheritable forms or phenotypes.

39 hods that will allow exogenous imposition of inheritable gene-specific methylation patterns has poten

40 Pseudogenes are inheritable genetic elements formally defined by two pro

41 ain anatomy is strikingly diverse and highly inheritable: genetic factors may explain up to 80% of it

42 the development of small animal models with inheritable HCV susceptibility.

43 prue, or gluten-sensitive enteropathy, is an inheritable human disease of the small intestine that is

44 Inheritable long-QT syndrome (LQTS) is a disease in whic

45 rect a point mutation in a site-specific and inheritable manner in extrachromosomal and chromosomal t

46 X syndrome (FXS) is the most common form of inheritable mental retardation caused by transcriptional

47 cy" impacting offspring immunity and suggest inheritable microbiota may contribute to the modern patt

48 a leading target for mutations implicated in inheritable muscle diseases.

49 An inheritable muscular hypertrophy was recently described

50 ut 50% alleviation of the malfunction of the inheritable mutated (alpha1beta2gamma2L(K289M)) GABA(A)

51 Inheritable mutations in nucleotide excision repair (NER

52 gic diseases are associated with acquired or inheritable mutations in the GFI1 and GFI1B genes.

53 Many inheritable mutations on HNF1beta are the monogenic caus

54 ight ventricular cardiomyopathy (ARVC) is an inheritable myocardial disorder associated with fibrofat

55 reveal the plasticity and the epigenetically inheritable nature of centromeric chromatin organization

56 ents with Sjogren-Larsson syndrome (SLS), an inheritable neurocutaneous disorder.

57 m spectrum disorder (ASD) is a prevalent and inheritable neurodevelopmental disorder.

58 nt the first evidence for the development of inheritable neuroectodermal tumors induced by the human

59 ophic lateral sclerosis (ALS) through either inheritable or nonheritable modifications.

60 ermed systemic acquired resistance (SAR), is inheritable over a few generations.

61 in chromatin structure are often cellularly inheritable over at least a limited number of generation

62 iants," each with a distinct, epigenetically inheritable phenotype.

63 study, the authors test the hypothesis that inheritable phenotypes can be discovered and quantified

64 olled by epigenetic mechanisms that generate inheritable phenotypic diversity without altering the DN

65 (PcG) proteins contribute to epigenetically inheritable phenotypic variability.

66 This report describes the analysis of inheritable pituitary adenomas induced by expression of

67 t mutations are not essential for generating inheritable PRD.

68 The number of inheritable [PSI(+)] particles is significantly reduced

69 pase (ET-FLP), transgenic lines that provide inheritable, reproducible, and tissue-specific FLP and a

70 Transgenic animals exhibited higher and inheritable resistance to BmNPV infection than wild-type

71 tyrosinase gene, resulting in permanent and inheritable restoration of tyrosinase enzymatic activity

72 lective utilization of histone variants, and inheritable RNA molecules play pivotal roles in maintain

73 tions in keratin genes can cause a number of inheritable skin disorders characterized by intraepiderm

74 hing, an alteration between two quasi-stable inheritable states.

75 ther demonstrated that VIGS in C. elegans is inheritable, suggesting that VIGS has the potential to g

76 The plants possess a complex, maternally inheritable syndrome of nucleo-cytoplasmic incompatibili

77 In both racial groups, however, the inheritable thrombophilic risk factors prevalent in Cauc

78 genetically encoded enzyme expression, thus inheritable to the cell progeny; and (iv) conditional an

79 tiple levels of control, from those that are inheritable to those that are highly responsive to envir

80 ete Nereis (Hediste) diversicolor exhibiting inheritable tolerance to extreme copper contamination in

81 These results support the hypothesis of an inheritable trait in congenital and childhood nonimmune

82 xcise these elements became a non-Mendelian, inheritable trait in the next generation and did not req

83 these data indicate a differential impact of inheritable traits on the environmental regulation of ad

84 to the DC lineage is driven by parallel and inheritable transcriptional programs in HSCs and is rein

85 all Ab-mucin binding avidity, and creates an inheritable virion-mucin affinity.