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1 At 25 mug/mL, these compounds inhibited LPO by 11-87%, COX-1 and -2 enzymes by 0-35% a

2 Results suggest metals inhibit respiration by 13-30% relative to reference site

3 o cell uptake was sodium-independent and was inhibited >/=95% by 2-amino-2-norbornanecarboxylic acid

4 I, and these interactions are stimulated and inhibited, respectively, by 2-oxoglutarate, providing a

5 eeks initiated at the time of diabetes onset inhibited RVP by 42% (P = 0.013) and 83% (P < 0.001) at

6 rol, whereas HMGB1 at the same concentration inhibits repair by 45%.

7 l(-) concentrations to sustain transport, is inhibited noncompetitively by 5-HT, and is more sensitiv

8 Concentrations inhibiting feeding by 5, 50, and 95% after one day of ex

9 ly inhibited rAAV2 nuclear translocation and inhibited transduction by 50 to 70%.

10 Aged garlic inhibited AGEs by 56.4% compared to 33.5% for an equival

11 techin, quercetin and gallic acid (60mug/ml) inhibited growth by 65.2%, 62.2%, 81.0% and 71.0%, respe

12 In inside-out patches, currents were inhibited strongly by a combination of diamide/GSH or H(

13 We conclude that FliW inhibits CsrA by a noncompetitive mechanism that differs

14 ST-binding factor, activin betaB (ACTbetaB), inhibits neurogenesis by a distinct mechanism: whereas G

15 y a competitive mechanism, whereas verapamil inhibits transport by a non-competitive mechanism, thus

16 Glucocorticoids can inhibit inflammation by abrogating the activity of NF-ka

17 formed by the SAC has recently been shown to inhibit Cdc20 by acting as a pseudosubstrate inhibitor,

18 Many neurotransmitters directly inhibit neurons by activating G protein-gated inwardly r

19 nces anti-autophagic signaling pathways, and inhibits autophagy by activating the G protein.

20 The data suggest that blue/green light inhibits proliferation by activating TRPV1, and increasi

21 lysine-reactive fragment electrophiles that inhibit enzymes by active site and allosteric mechanisms

22 ollowing the hypothesis that these compounds inhibit NAAA by acylation of the catalytic cysteine, we

23 intermediates (such as organic chloramines) inhibit ENaC by affecting channel gating, which could be

24 wo selected AMPs in this study were found to inhibit viruses by agglutinating its virions to form agg

25 In vitro, RGS proteins have been shown to inhibit signaling by agonists at the mu-opioid receptor,

26 Importantly, vanitaracin A inhibited infection by all HBV genotypes tested (genotyp

27 Moreover, ezetimibe inhibits infection by all major HCV genotypes in vitro a

28 cysSA expression, suggesting that it likely inhibits AC by allosteric interference.

29 ion profiles revealed that elevated pressure inhibited invasion by altering the chemical composition

30 rimary site of infection at least in part by inhibiting phagocytosis by alveolar macrophages.

31 y gene Nod2 from intestinal abnormalities by inhibiting colonization by an inflammatory Bacteroides s

32 Remarkably, 5-NT also inhibits infection by an alphavirus and a coronavirus.

33 CaMKII inhibits NHE3 by an effect on its turnover number, not c

34 ding of cdb3-PO4 to erythrocyte membranes is inhibited both by antibodies against the SH2 signature s

35 mutant (L858R/T790M, DM EGFR), which is not inhibited selectively by any approved kinase inhibitor.

36 TRPA1 did not appear to be activated or inhibited directly by aristolochic acid.

37 SH3 and SH2 domains inhibit Abl by assembling onto the catalytic domain, all

38 ole antifungal drugs showed that CYP126A1 is inhibited strongly by azoles containing an imidazole rin

39 It inhibits transcription by bacterial RNA polymerase.

40 rtilin, a pro-survival molecule, is known to inhibit apoptosis by binding and inhibiting p53, but its

41 e data suggest that the Cu-ATCUN derivatives inhibit bacteria by binding to the membrane, promoting o

42 protein called Glomulin (GLMN) was shown to inhibit CRLs by binding to the RING BOX (RBX1) subunit a

43 exemplifies a class of antiviral agents that inhibit HIV by binding to the highly glycosylated envelo

44 14-3-3 proteins inhibit NR by binding to a conserved phosphorylation sit

45 CBR703 series antimicrobials allosterically inhibit transcription by binding to a conserved alpha he

46 e" model suggests that macrolide antibiotics inhibit translation by binding inside the ribosome tunne

47 hic studies, we demonstrate that MTM and PKM inhibit translation by binding to overlapping sites in t

48 ta suggest that MARV-neutralizing antibodies inhibit virus by binding to infectious virions at the ex

49 AFN-1252 inhibited CtFabI by binding to the FabI.NADH complex wit

50 o the outer mitochondrial membrane, where it inhibits apoptosis by binding Bax and inhibiting Bax-ind

51 y and that the phosphorylated regulator DivK inhibits CckA by binding to DivL.

52 r, but in this paper, we show that Mad2 also inhibits Cdc20 by binding directly to a site required to

53 Instead, we provide evidence that SidA inhibits division by binding directly to FtsW to prevent

54 Liver angiopoietin-like 3 (ANGPTL3) inhibits lipolysis by binding to lipoprotein lipases.

55 Together our data suggest that pTRS1 inhibits PKR by binding to conserved amino acids in the

56 We show here that Bmh inhibits transcription by binding to Adr1 at promoters t

57 Here, we show that FMRP inhibits translation by binding directly to the L5 prote

58 s are a suite of aromatic compounds that can inhibit fermentation by biofuel-producing microbes.

59 Abs targeted to VE-cadherin monomers inhibit angiogenesis by blocking this adherens junction

60 e find that in the pluripotent epiblast they inhibit apoptosis by blocking the expression of the proa

61 V to infect leukocytes, whereas CCR5 ligands inhibit infection by blocking CCR5 engagement with HIV g

62 face E2 glycoproteins and therefore probably inhibit infectivity by blocking the conformational chang

63 s, which accumulate following demyelination, inhibit remyelination by blocking the differentiation of

64 Overall, Shenks inhibited fibrosis by blocking TGF-beta pathway and modu

65 onfirms the hypothesis that transport can be inhibited simply by blocking conformational transitions

66 round the receptor-attachment site, probably inhibiting infection by blocking cell attachment.

67 We further demonstrate that inhibiting NETosis by blocking neutrophil elastase or by

68 inal (BET) bromodomain inhibitor, JQ1, which inhibits BRD4 by blocking its association with chromatin

69 Tropomyosin inhibits Myo1p by blocking its ability to form productiv

70 These findings suggest that FMRP inhibits translation by blocking the essential component

71 In contrast, NFRKB inhibits UCH37 by blocking the ubiquitin-binding site an

72 In contrast, EBOV VP35 can inhibit activation by both PAMPs.

73 specifically bound to the RSV fusion bundle inhibited infection by both laboratory and clinical RSV

74 he proliferation of GCase-deficient HSCs was inhibited significantly by both GL1 and Lyso-GL1, sugges

75 Ibogaine noncompetitively inhibited transport by both SERT and the homologous dopa

76 Such stimulatory effect was inhibited, however, by both dominant-negative mutants of

77 n, rifaximin, and metronidazole) effectively inhibited sporulation by C. difficile.

78 Inhibiting AKT by caffeine blocked UVB-induced COX-2 up-

79 encode messenger RNA endonucleases (mRNases) inhibiting translation by catalytic degradation of mRNA,

80 Nitric oxide (NO) inhibits exocytosis by chemically modifying N-ethylmalei

81 o results revealed that plaque formation was inhibited/reduced by chlorhexidine and honey rinses.

82 Inhibiting autophagy by chloroquine, bafilomycin, 3-meth

83 ATPase activity and CFTR channel gating were inhibited severely by CL1 peptide, suggesting that NBD1/

84 Here we show that VapC20 of M. tuberculosis inhibits translation by cleavage of the Sarcin-Ricin loo

85 Caspase-10 inhibits autophagy by cleaving the BCL2-interacting prot

86 Here, we show that Gam inhibits RecBCD by competing at the DNA-binding site.

87 des (< 300 Da) that could either activate or inhibit PDK1 by conjugation to the PIF pocket, thus disp

88 Here we show that ALK1 inhibits angiogenesis by cooperating with the Notch path

89 er of Tregs to secondary NOD.scid recipients inhibited autoimmunity by cotransferred NOD effector T c

90 discovery of fosfomycin, which specifically inhibits MurA by covalent modification of the active sit

91 Prolonged NO exposure irreversibly inhibits respiration by covalent modification of mitocho

92 We further found that ferroptosis inducers inhibit GPX4 by covalently targeting the active site sel

93 o Abs from patients with autoimmune diseases inhibit IKr by cross-reacting with the HERG channel like

94 L-1beta implantation, while bevacizumab only inhibited angiogenesis by day 2 after implantation.

95 In contrast, activation of ER in ASCs inhibited adipogenesis by decreasing the recruitment of

96 that of Bcl-2, selectively targets VDAC1 and inhibits apoptosis by decreasing VDAC1-mediated Ca(2+) u

97 Genetic loss of TCF1 inhibited differentiation by delaying exit from pluripot

98 bitor of endocytosis, demonstrated that they inhibit endocytosis by different mechanisms.

99 This approach offers a new paradigm to inhibit immunosuppression by direct targeting of MDSC fu

100 Instead, IVIg inhibited phagocytosis by direct blockade of FcgammaRs.

101 and show that it both promotes excision and inhibits integration by direct protein-protein interacti

102 have shown that emixustat stereoselectively inhibits RPE65 by direct active site binding.

103 ll lymphoma-X large (Bcl-xL) are proposed to inhibit autophagy by directly binding to the BH3 domain

104 PTP1B inhibited BRK by directly dephosphorylating the Tyr-342

105 Here we find that miR-140-5p inhibits HCC by directly targeting Pin1 to block multipl

106 conclusion, we show that apoC-I and apoC-III inhibit lipolysis by displacing LPL from lipid emulsion

107 ive stress indirectly activates the normally inhibited CypD by displacing it from Trap1 complexes.

108 in the presence of CRY, nuclear entry of PER inhibits transcription by displacing CLOCK-BMAL1 from th

109 HA1 by recruiting PDK1, and K202 acetylation inhibits PDP1 by dissociating its substrate PDHA1, both

110 we show that two Acrs, AcrIIC1 and AcrIIC3, inhibit Cas9 by distinct strategies.

111 res ATP-hydrolysis-powered remodeling of the inhibited complexes by diverse molecular chaperones know

112 the DOB lesion efficiently and irreversibly inhibits repair by DNA polymerase beta (Pol beta), an in

113 In older AVM axons, let-7 inhibits regeneration by down-regulating LIN-41, an impo

114 e thalamocortical cells, but also indirectly inhibit them by driving inhibitory cells of the thalamic

115 Inhibiting transcytosis by dynamin blockade increased pa

116 ng by Escherichia coli DNA polymerase II and inhibits proofreading by E. coli DNA polymerase III, whi

117 otrypsin phenotype, CTRC variant p.G214R was inhibited poorly by eglin C, ecotin, or a CTRC-specific

118 Functional regulators inhibit motility by either disengaging or jamming the st

119 These observations suggest a strategy for inhibiting angiogenesis by either recapitulating miR-221

120 Mechanistic investigations indicated that inhibiting PARylation by either hyperthermia or PARPi in

121 rotocols and tested for alpha2beta1 integrin-inhibiting capabilities by ELISA.

122 an atomic model of the complex in which F1L inhibits C9 by engaging the active site in the reverse o

123 esults suggest that PI3K-activating hormones inhibit ROMK by enhancing its endocytosis via a mechanis

124 lation assay suggested that insulin and IGF1 inhibit ROMK by enhancing its endocytosis, a process tha

125 Metformin directly inhibited mTOR by enhancing PRAS40's association with RA

126 we find that the addition of new species can inhibit cooperation by eradicating secreting strains bef

127 egation and, presumably, internalization and inhibits infection by EV11-207.

128 he dense chromatin environment is thought to inhibit transcription by excluding transcription factors

129 ng site whose phosphorylation is believed to inhibit YAP by excluding it from the nucleus.

130 Collectively, the data revealed that nsp1 inhibited translation by exerting its effect on multiple

131 ylation of Thr464 present in the CDT2 degron inhibits recognition by FBXO11.

132 ength tau aggregation and are ineffective at inhibiting seeding by full-length fibrils.

133 TP) channels (Sur1(-/-) mice) at G1 could be inhibited further by G7.

134 ignificance as their structural modification inhibits activation by GABA.

135 wever, the molecular mechanism of this STAT3-inhibiting effect by galiellalactone has not been clarif

136 ta by cross-linking it to the EF hand domain inhibits stimulation by Gbetagamma without altering basa

137 ytes and in cultured macrophages showed that inhibiting ACAT1 by gene knockout or by pharmacological

138 Interestingly, inhibiting apoptosis by genetic ablation of TNFr1 signif

139 red wine and 100-fold dilution of green tea inhibited CaCCs by >50%.

140 Of them, 14 drugs inhibited CYP27A1 by >/=75% and were evaluated for in vi

141 duced by iron or 8-bromo-cAMP was delayed or inhibited, respectively, by H89, the inhibitor of protei

142 e dephosphorylation of OsRBR1 was completely inhibited only by high dose (300 nM) of the okadaic acid

143 interferon (IFN-gamma) was recently shown to inhibit replication by human BK polyomavirus in primary

144 Finally, a blocking antibody against beta8 inhibited immunosuppression by human Tregs in a model of

145 Surprisingly, the fibrils inhibited fertilization by immobilizing sperm.

146 The apoAI mimetic 4F was designed to inhibit atherosclerosis by improving HDL.

147 Conversely, DNA could inhibit fibrinolysis by increasing the susceptibility of

148 Lipid-free apoA-I and (A-I)rHDL inhibit inflammation by increasing DHCR24 expression, wh

149 (AES103 and GBT440) in clinical trials that inhibit polymerization by increasing oxygen affinity, on

150 ults in anti-inflammatory effects capable of inhibiting ACD by inducing immunosuppressive responses.

151 FITM3) is a cellular restriction factor that inhibits infection by influenza virus and many other pat

152 In conclusion, our data show that IL-18 may inhibit feeding by inhibiting the activity of BST Type I

153 We demonstrate that biguanides inhibit growth by inhibiting mitochondrial respiratory c

154 Periodontal bone resorption was inhibited significantly by injection of the anti-RANKL F

155 at an 'accessory' alpha-helix of Complexin-I inhibits release by inserting into the C-terminus of the

156 hesize that this class of chemical compounds inhibit DNMTs by interacting with the DNA substrate.

157 nt apo(a) variants were able to specifically inhibit HCV by interacting with infectious particles.

158 Bim inhibits autophagy by interacting with Beclin 1, an auto

159 Evidence indicates that YpfA inhibits motility by interacting with the flagellar moto

160 he pleckstrin homology (PH) domain of P-REX2 inhibits PTEN by interacting with the catalytic region o

161 to an as yet uncharacterized mechanism that inhibits infection by interfering with efficient synthes

162 HCV pseudoparticles into hepatoma cells and inhibit signaling by interferon alpha (IFNalpha), but ha

163 s LPS alone, but neutrophil infiltration was inhibited, likely by interrupting HA-CD44 interaction.

164 Thus, intracellular pathogens can inhibit autophagy by irreversibly inactivating Atg8 prot

165 proteins and cellular p53 and is ultimately inhibited again by its own products.

166 found on flat and concave membrane surfaces inhibit folding by kinetically trapping the peptide.

167 ics but, more importantly, can substantially inhibit recognition by KSHV-specific CD4 T cells prior t

168 st active compound identified in the screen, inhibits intoxication by lethal toxin and blocks the ent

169 r until a single word is selected ("formula" inhibits "formal" by lexical competition) or (2) are use

170 This pathway is efficiently inhibited only by ligands that occupy both binding sites

171 Lm211 can inhibit Nrg1III by limiting protein kinase A (PKA) activ

172 Ang-2 inhibits atherosclerosis by limiting LDL oxidation via s

173 Rho also inhibits itself by local recruitment of actomyosin and t

174 ation creates a unique hydrogel surface that inhibits recognition by macrophages and fibrous depositi

175 ion, whereas the application of anti-miR-132 inhibits neovascularization by maintaining vessels in th

176 intestinal pathogen, Salmonella Typhimurium, inhibits anorexia by manipulating the gut-brain axis.

177 nd a4 together using isoform-specific siRNAs inhibited invasion by MCF10CA1a cells.

178 ges the Beclin 1-LC8 interaction and thereby inhibits autophagy by mislocalizing Beclin 1 to the dyne

179 oxidative phosphorylation (OXPHOS) in cancer inhibit apoptosis by modulating ROS production and cellu

180 hese results demonstrate that FOXP3(+) Tregs inhibit atherosclerosis by modulating lipoprotein metabo

181 erefore, in a nucleic acid-driven model, HRG inhibits thrombosis by modulating the intrinsic pathway

182 This finding suggests that Nun may inhibit translocation by more than one mechanism.

183 The ladders were not observed when NER was inhibited either by mouse monoclonal antibody (5F12) to

184 esent a class of immunomodulatory drugs that inhibit signaling by multiple cytokines.

185 These results indicate that WNK1 inhibits autophagy by multiple mechanisms.

186 work formation, and AKT phosphorylation were inhibited only by murine anti-beta3 integrin antisera an

187 Therefore, versican cleavage can be inhibited substantially by mutation of Glu(441), Ser(507

188 ators of human butyrylcholinesterase (hBChE) inhibited covalently by nerve agent OPs, sarin, cyclosar

189 ent, significantly delayed diabetes onset by inhibiting infiltration by not only insulin-specific CD4

190 he MAbs could block carbohydrate binding and inhibit hemagglutination by NV rVLP.

191 We show that A238L competitively inhibits CN by occupying a critical substrate recognitio

192 by 87 +/- 10%, HDL dialyzed without calcium inhibited oxidation by only 58 +/- 19% (P=0.004).

193 We then reversibly inhibited V1 by optogenetically activating parvalbumin-e

194 fection are distinct from those required for inhibiting infection by other viruses.

195 Inhibiting EMT by overexpressing the microRNA miR-200 do

196 Inhibiting apoptosis by overexpression of antiapoptotic

197 IV-1 maturation and that small molecules can inhibit maturation by perturbing molecular motions.

198 In conclusion, inhibiting SIDS by pharmacological blockade of body's st

199 We provide evidence to show that RSK2 inhibits ASK1 by phosphorylating S83, T1109, and T1326 t

200 This study tested the hypothesis that cGMP inhibits NHE3 by phosphorylating it and altering its mem

201 ating TCF3, a transcriptional repressor, but inhibits transcription by phosphorylating LEF1, a transc

202 asminogen efficiently and both proteases are inhibited rapidly by plasminogen activator inhibitor-1 (

203 ulation of CSPBP in mosquito salivary glands inhibited invasion by Plasmodium organisms.

204 ly shown that the ingestive phase of feeding inhibits behaviors by presynaptic inhibition of mechanos

205 cognized a quaternary antigenic site and may inhibit fusion by preventing F refolding or by blocking

206 Inactivation of NCK1 and 2 inhibits polarity by preventing Cdc42 and Pak2 activatio

207 These results indicate that FLCN inhibits tumorigenesis by preventing AMPK-dependent HIF

208 We show that the major effect of 9-1-1 is to inhibit resection by promoting the recruitment of Rad9(5

209 tiation of early-stage cancers, but can also inhibit tumorigenesis by promoting permanent cell growth

210 , under sypG-overexpressing conditions, SypE inhibited biofilms by promoting the phosphorylation of a

211 n the heptamer and (ii) that glycoconjugates inhibited VCC by promoting its assembly to a water-solub

212 and after metabolic stress, and that TAT-p27 inhibits apoptosis by promoting autophagy in glucose-dep

213 The small G protein ARL-8 inhibits assembly by promoting dissociation, while a JNK

214 Overexpression of dnaC inhibits replication by promoting continual rebinding of

215 Dif1 protein inhibits RNR by promoting nuclear import of Rnr2-Rnr4.

216 w that SGK1-mediated phosphorylation of WNK1 inhibits ROMK by promoting its endocytosis.

217 In conclusion, CsA and FK506 inhibit proteinuria by protecting against PAN-induced po

218 emonstrate that gut epithelial VDR signaling inhibits colitis by protecting the mucosal epithelial ba

219 K321 acetylation inhibits PDHA1 by recruiting PDK1, and K202 acetylation

220 Notably, miR-130a inhibited autophagy by reducing autophagosome formation,

221 ent; blocking DC synthesis of fatty acids or inhibiting adipogenesis (by reducing endoplasmic reticul

222 rdin reductase (hBVR), a Ser/Thr/Tyr kinase, inhibits apoptosis by reducing biliverdin-IX to antioxid

223 miR-375 inhibits autophagy by reducing expression of ATG7 and im

224 alysis and binding assays, we show that Gle1 inhibits Ded1 by reducing its affinity for RNA.

225 Finally, we found that miR-137 inhibits mitophagy by reducing the expression of the mit

226 ely, our results indicate that ceruloplasmin inhibits myeloperoxidase by reducing Compound I and then

227 ylation at another tyrosine residue, Tyr-94, inhibits PDP1 by reducing the binding ability of PDP1 to

228 ASC expression in primary melanoma inhibits tumorigenesis by reducing IKKalpha/beta phospho

229 easing Bax and reducing Bcl-2, but otherwise inhibiting apoptosis by reduction of caspase-3 and cytoc

230 alpha1(IV)NC1 inhibits angiogenesis by regulating MAPK activation, thi

231 kinetic methods, which suggest the compound inhibits Syk by reinforcing the natural regulatory inter

232 Here we show that the DEAD-box RBP DDX5 inhibits reprogramming by repressing the expression and

233 AMP and ketone bodies together can therefore inhibit lipogenesis by restricting localization of ChREB

234 [SV5]) interacts with LGP2 and cooperatively inhibits induction by RIG-I ligands.

235 ssically mediating the kinase arm, PI3Kgamma inhibits PP2A by scaffolding and sequestering, playing a

236 des an endoribonucleolytic toxin, MazF, that inhibits growth by sequence-specific cleavage of single-

237 assical; and whether quinoline antimalarials inhibit crystallization by sequestering hematin in the s

238 g protein tomosyn has been shown to potently inhibit exocytosis by sequestering SNARE proteins in non

239 The ES can inhibit function by sequestering residues involved in re

240 using a single domain antibody fragment that inhibits LMO2 by sequestering it in a non-functional for

241 blocks ERK-dependent gene transcription and inhibits proliferation by sequestering ERK in the cytopl

242 essors of cytokine signaling (SOCS) proteins inhibit signaling by serving as substrate receptors for

243 show that ETS-5 acts to promote roaming and inhibit quiescence by setting the internal "satiety quot

244 tudies showed that TSPAN9 depletion strongly inhibited infection by several viruses that fuse in earl

245 (CA-alpha1) significantly inhibits; although inhibiting alpha1AMPK by short hairpin RNA knock-down or

246 crobes provide signals that both promote and inhibit autoimmunity by signaling through different rece

247 f the heparan sulfate proteoglycan perlecan, inhibits angiogenesis by simultaneously binding to the a

248 omain endonucleases that, in enterobacteria, inhibit translation by site-specific cleavage of initiat

249 In contrast, VapC20 of M. tuberculosis inhibits translation by site-specific cleavage of the un

250 m LT2 encodes VapC, a tRNase that reversibly inhibits translation by site-specific cleavage of tRNA(f

251 discovered that elevated levels of c-di-GMP inhibit swarming by skewing stator selection in favor of

252 We show that inhibiting APEX1 by small molecule inhibition or small i

253 These pathways can either promote or inhibit colonization by specific subsets of commensal ba

254 This pathway represents a new mechanism to inhibit neurons by specifically regulating Ca(2+) channe

255 onmental stress, the phosphatase calcineurin inhibits Hcm1 by specifically removing activating phosph

256 o and in vivo experiments, we found that IgG inhibits motility by specifically binding to the O-antig

257 ficient mice, suggesting that endogenous LPM inhibit differentiation by SPM.

258 that volatile anesthetics such as isoflurane inhibit NaV by stabilizing the inactivated state or alte

259 ucleic acids crosslinking suggests that NusG inhibits backtracking by stabilizing the minimal transcr

260 inhibitors or siRNAs targeted to PARP-1, can inhibit HDR by suppressing expression of BRCA1 and RAD51

261 Mechanistically, CS and SULT2B1b inhibited gluconeogenesis by suppressing the expression

262 KCa3.1 blockade or knockdown inhibited proliferation by suppressing the rise in [Ca(2

263 Intriguingly, Deltex2 inhibits myogenesis by suppressing MyoD transcription, a

264 Viral infection inhibits reproduction by suppressing vitellogenesis, cau

265 The T3-specific antibody inhibited hemagglutination by T3 virions but not ISVPs,

266 r, and was suppressed when ER signalling was inhibited either by tamoxifen in vitro or letrozole in h

267 that diverse chemical structures are able to inhibit Porcn by targeting its putative active site.

268 results support the idea that antisense RNAs inhibit retrotransposition by targeting Ty1 protein func

269 CS and SULT2B1b inhibited gluconeogenesis by targeting the gluconeogenic

270 pression of miR-503 promotes cell growth and inhibits apoptosis by targeting PDCD4.

271 This drive inhibits motoneurons by targeting both metabotropic GABA

272 d a benzodiazepine compound that selectively inhibits YFV by targeting the viral NS4B protein.

273 channel activity and invasive potential were inhibited pharmacologically by tetrodotoxin or genetical

274 establish that yeast sHsps, Hsp26 and Hsp42, inhibit prionogenesis by the [PSI+] prion protein, Sup35

275 the open mutant of Gbeta(5)-RGS7 was able to inhibit signaling by the truncated M3R.

276 Chemotaxis was inhibited >90% by the S6K inhibitors rapamycin and bisin

277 asal fluid transport by ANP (5 muM) that was inhibited completely by the ANP receptor antagonist anan

278 mal targeting and secretion of mHtt could be inhibited efficiently by the phosphatidylinositol 3-kina

279 Netrin-1-induced JNK activation was inhibited either by the JNK inhibitor or an anti-DCC fun

280 e to a broad range of H7 subtype viruses and inhibited hemagglutination by the novel H7 hemagglutinin

281 n A and other high affinity ligands directly inhibited signaling by the low affinity ligands BMP-2, B

282 ceptor and GRP-BB2 receptor systems and itch-inhibiting effects by the dynorphin A-KOP receptor syste

283 pancreatic ductal adenocarcinoma (PDAC) that inhibiting signaling by the myeloid growth factor recept

284 ther known HIV-suppressive chemokines, CXCL4 inhibits infection by the majority of primary HIV-1 isol

285 , demonstrating the therapeutic potential of inhibiting USP7 by this approach.

286 platin-resistant human ovarian cancer cells, inhibiting IDO by transcriptional deregulation of the au

287 ns to inhibit ADK, while AL2 in addition can inhibit silencing by transcriptionally activating cellul

288 t, during Hedgehog signaling, ligand binding inhibits Patched by trapping it in an inactive conformat

289 We inhibited STAT5 by treating Mo-DCs with JQ1, a selective

290 cytoplasmic or luminal sides of the membrane inhibited RyR2 by two distinct modes: 1) a fast block co

291 ween the prodomain and catalytic domain, and inhibits MMP9 by two mechanisms.

292 We conclude that isoflurane inhibits NaChBac by two distinct mechanisms: (i) as a ch

293 Salmonella enterica was previously shown to inhibit growth by unknown mechanisms.

294 molecules p21 and p27, whereas IFN-gamma may inhibit proliferation by up-regulating antiproliferative

295 UB1-2 domains not only bound MDTCS, but also inhibited activity by up to 2.5-fold.

296 Mang-NPs also inhibited EMT by up-regulating E-cadherin and inhibiting

297 were diminished when phagocytic activity was inhibited pharmacologically by using annexin V to block

298 The T1-specific antibody inhibited hemagglutination by virions and ISVPs, probabl

299 ne cholesterol with methyl-beta-cyclodextrin inhibited infection by virions but had no effect when in

300 the principal reproductive(s) of a colony to inhibit reproduction by worker colony members.