ライフサイエンスコーパス: inhibiting

1 of shrub expansion remain poorly understood, inhibiting accurate incorporation of shrub effects into

2 our results demonstrate that, in addition to inhibiting actin binding, Ser-3 modification favors form

3 Furthermore, GMF synergized with Coronin in inhibiting actin nucleation by Arp2/3 complex.

4 antioxidant capacity of the extract and its inhibiting activity against alpha-glucosidase, pancreati

5 d protein extract resulted in higher trypsin inhibiting activity, when compared to the industrial met

6 serum divalent cations eliminate myotonia by inhibiting AfD and NaPIC.

7 antibacterial arsenal is composed of growth-inhibiting agents that target rapidly-dividing planktoni

8 rolling tumor growth compared to transiently inhibiting Akt.

9 It broadly affected the T cell compartment, inhibiting all cell subsets (CD4, CD8, WC-1, and gammade

10 xamples resulting from these efforts in both inhibiting and stabilizing specific 14-3-3 protein compl

11 IGFBP7 abrogates tumors by inhibiting angiogenesis and inducing cancer-specific sen

12 polysaccharide in shielding OmpA and thereby inhibiting anti-OmpA MAb binding to clinical isolates.

13 culating strains enable the evasion of virus-inhibiting antibody responses, resulting in vaccine fail

14 dritic cell (DC) effector function; and (iv) inhibiting antitumor adaptive T cell immunity via the pr

15 Thus, reducing 27-OH levels or inhibiting AP-N maybe a useful strategy in the preventio

16 chick otic vesicle prevented canal fusion by inhibiting apoptosis.

17 Given that inhibiting AR transcriptional activity or androgen synth

18 Specifically inhibiting AS activity in these mice is a promising ther

19 Inhibiting ATG4B in combination with radiotherapy in tre

20 Thus, by inhibiting ATGL, HIG2 acts downstream of HIF-1 to seques

21 Inhibiting autophagy-mediated lipid degradation or fatty

22 In addition, we review the potential in inhibiting AXL for the development of different therapeu

23 re growth cone directive molecules known for inhibiting axon regeneration after injury.

24 brane and disrupt redox homeostasis, thereby inhibiting bacterial growth.

25 Inhibiting BDNF's receptor, TrkB, ERK/MAP kinase activat

26 enantiomer that is structurally incapable of inhibiting BET bromodomains, which resulted in a minimal

27 1 plays an essential role in BR signaling by inhibiting BIN2 through dual mechanisms of blocking subs

28 ritical residue of the N-terminal linker for inhibiting binding of the VWF A1 domain to GpIbalpha on

29 improves the quality of newly formed bone by inhibiting BMP2 induced fatty cyst-like structure and in

30 ere effective in suppressing tumor growth by inhibiting both AR-induced transcription and mTOR-induce

31 sis of Hri(-/-) , eAA, and Atf4(-/-) mice by inhibiting both HRI and mTORC1 signaling.

32 can fuel low-frequency synaptic function and inhibiting both underlies loss of synaptic transmission

33 es copper levels and MAPK signaling, thereby inhibiting BRAF(V600E)-driven melanoma tumor growth.

34 vels via bortezomib treatment or by directly inhibiting BRD4 binding via JQ1 treatment, prevents prog

35 maintaining the MaSC niche, and subsequently inhibiting breast cancer initiation and disease progress

36 nt reuterin producers, with L. reuteri 17938 inhibiting C. difficile growth at a level on par with th

37 (RyR) activity through an activating and an inhibiting Ca(2+)-binding site located on the cytoplasmi

38 e previously shown to be more efficacious at inhibiting Ca(2+)-triggered exocytotic release than wild

39 ssion and caused myofibril disarray, whereas inhibiting Calcineurin activity attenuated FoxO-mediated

40 tions lowered the glycemic index probably by inhibiting carbohydrate hydrolyzing enzyme activity whic

41 SH/GSSG in three breast cancer cell lines by inhibiting CBS.

42 ot only improving barrier function, but also inhibiting CC formation both in vitro and in vivo.

43 Functional studies confirmed that inhibiting CDK5-mediated RALB activation with a clinical

44 eby reducing AR transcriptional activity and inhibiting cell growth.

45 nitor cells by encouraging proliferation and inhibiting cellular senescence.

46 matin mutants could be partially restored by inhibiting cep-1/p53, endogenous meiotic double strand b

47 shifts in cell-wide gene expression through inhibiting chaos-generating motifs.

48 Exposure of Xenopus embryos to AChE-inhibiting chemicals results in severe defects in intest

49 odels of inflammation yet was less potent at inhibiting chemotaxis in vitro with an IC50 of 21 nm Fur

50 eading to the conclusion that in addition to inhibiting chymosin, native whey proteins present a phys

51 ) mice, emphasizing the importance of PTH in inhibiting Cldn14.

52 icance: This provocative study suggests that inhibiting complement activation may heighten immunother

53 cal analysis suggests that it neutralizes by inhibiting conformational changes required for entry.

54 eate the protolerogenic properties of EPO in inhibiting conventional T cells while simultaneously pro

55 Inhibiting COX-2 or microsomal prostaglandin E synthase-

56 levels via two distinct mechanisms, thereby inhibiting critical cell functions, including cellular p

57 artery explants to hypoxia-reoxygenation, or inhibiting CSE.

58 a disinfectant in stratified stagnant pipes, inhibiting culturable Legionella and biofilm formation,

59 The clinical utility of inhibiting cytochrome P450 17A1 (CYP17), a cytochrome p4

60 We investigated whether inhibiting cytokinesis in the liver slows tumor growth w

61 ddition of MEK-inhibiting trametinib to BRAF-inhibiting dabrafenib was able to overcome acquired part

62 n barrier that promotes podocyte survival by inhibiting dendrin pro-apoptotic function.

63 unteract metabolic insecticide resistance by inhibiting detoxification enzymes or transporters.

64 ins HSC long-term reconstitution activity by inhibiting differentiation and cell cycle entry.

65 , could suppress CRAF-fusion oncogenicity by inhibiting dimer-mediated signaling.

66 bited RNA and protein biosynthesis while not inhibiting DNA biosynthesis using (3)H-radiolabeled prec

67 of CcdA to the toxin CcdB prevents CcdB from inhibiting DNA gyrase and thereby averts cell death.

68 Inhibiting DNA methylation activates COL2 expression, an

69 ities and associated gene silencing, through inhibiting DNA methyltransferases (DNMTs) is an importan

70 ch exerts antileukemic effects, primarily by inhibiting DNA synthesis in proliferating cells.

71 ylation impacts Notch signalling activity by inhibiting DNA-binding of Su(H), potentially affecting b

72 KIF21B also contains a motor-inhibiting domain that does not fully block the interact

73 eatly affected by the viral interferon (IFN)-inhibiting domains (IID).

74 Aergic neurons facilitate mechanical pain by inhibiting dorsal horn enkephalinergic/GABAergic interne

75 asses of cancer that may benefit from CDK4/6-inhibiting drugs such as abemaciclib.

76 M) ameliorated disease-related phenotypes by inhibiting drusen proteins and inflammatory and compleme

77 as a negative regulator of PCP signaling by inhibiting Dvl through a novel polyubiquitination mechan

78 e traffic to photoreceptor disc formation by inhibiting ectosome release from the cilium.

79 A significant increase of the ACE-inhibiting effect was observed following butanol extract

80 ection and promoted bacterial persistence by inhibiting effector T cells.

81 ications from ubiquitination to neddylation, inhibiting EGFR dynamics in response to an acute ligand

82 In addition, directly inhibiting eIF4A with silvestrol significantly suppresse

83 The wound healing assay reveals that inhibiting either BCL2L11 or CDH9 will enhance the migra

84 them, ginsenoside Ro was the most potent in inhibiting embryonic implantation within non-cytotoxic c

85 dly acts as a Rap1 GTPase inhibitor, thereby inhibiting endothelial cell motility, independently of p

86 inducing dorsal Jag1 expression but also by inhibiting endothelin 1 (Edn1) expression in the pharyng

87 gether, anti-VEGF/VEGFR drugs act in part by inhibiting eNOS, causing vasocontraction, MV collapse to

88 ls from GTPs and BSp are highly effective in inhibiting ERalpha-negative breast cancer due at least i

89 esponsible for promoting integration and for inhibiting excision.

90 er are frequently implicated as promoting or inhibiting exciton mobility in such systems.

91 or-kappa B (NF-kappaB), while simultaneously inhibiting expression of microRNA-9, which targets the P

92 terference mechanism that is responsible for inhibiting expression of the coding NDC80 mRNA isoform.

93 2, which promote memory strengthening while inhibiting extinction.

94 Inhibiting FDFT1 was most effective, with zaragozic acid

95 ndependent phenotype that can be reverted by inhibiting FGFR2 signaling.

96 ng a comprehensive list of miRNAs capable of inhibiting flavivirus replication.

97 hotrexate during neurulation induces NTDs by inhibiting folate interaction with its uptake systems.

98 RKIP transitions from inhibiting Raf-1 to inhibiting G-protein-coupled receptor kinase 2 upon phos

99 its rewarding actions, at least in part, by inhibiting GABAergic input onto substance P (SP) neurons

100 mulates worker-like hunting behaviors, while inhibiting gamergate behaviors, such as dueling and egg

101 Inhibiting glucose reabsorption by sodium glucose co-tra

102 Thus, targeting peripheral CB1R or inhibiting GLUT2 dynamics in RPTCs has the potential to

103 We finally show that inhibiting glutamine metabolism attenuates HCV infection

104 and demonstrate the therapeutic potential of inhibiting GnT-III as a treatment for controlling EOC gr

105 Inhibiting GrmA reduced excessive IL-8 and MCP-1 synthes

106 h zinc levels can impair cellular processes, inhibiting growth of many pathogenic bacteria, including

107 ts had minimal pre-existing hemagglutination inhibiting (HAI) antibodies and TIV induced either no, l

108 affects histone acetylation by targeting and inhibiting HDAC complexes, resulting in the hyperacetyla

109 ediators of HDM allergy development and that inhibiting HDM engagement with PC receptors in the lung

110 Inhibiting HER2 expression in bone tumor xenografts redu

111 ses of small-molecule inhibitors of LIMK for inhibiting HIV infection.

112 ranscriptase-mediated DNA synthesis, thereby inhibiting HIV-1 replication.

113 Statins lower cholesterol by inhibiting HMG-CoA reductase, the rate-limiting enzyme o

114 ccines (TBV) which aim to control malaria by inhibiting human-to-mosquito transmission show considera

115 t miR-195 and CUGBP1 dampen IGF signaling by inhibiting IGF2R translation.

116 s human neonatal regulatory B cells, thereby inhibiting immunological responses.

117 d cells and block lytic replication, thereby inhibiting infection of new cells.

118 ion, suggesting that restoring mitophagy and inhibiting inflammasome activation may serve as novel ta

119 I, we speculated that aPC ameliorates IRI by inhibiting inflammasome activation.

120 CD70 plays a novel immune checkpoint role in inhibiting inflammatory T cell responses.

121 reby blocks the activity of these cytokines, inhibiting interleukin-23-dependent production of interl

122 3.Hepcidin controls systemic iron levels by inhibiting intestinal iron absorption and iron recycling

123 Notably, we provide proof-of-principle that inhibiting IP3R3 degradation in PTEN-deregulated cancers

124 alateral motor cortex and, accordingly, that inhibiting ipsilateral regions can improve motor learnin

125 itating oligomerization and negative charges inhibiting it.

126 t signal transduction, with functions beyond inhibiting ITAM-mediated platelet activation.

127 een focused on targeting it, most notably by inhibiting its AURKB kinase subunit.

128 gG1 monoclonal antibody that binds to PD-L1, inhibiting its binding to PD-1, which inactivates T cell

129 tral metabolism in Listeria monocytogenes by inhibiting its pyruvate carboxylase (LmPC), a biotin-dep

130 gy balance, and the therapeutic intervention inhibiting JNK activities represents a promising approac

131 o attenuates H2O2-induced Bim activation via inhibiting JNK phosphorylation, subsequently preventing

132 viously unrecognized molecular mechanism for inhibiting junctional CDC-42 to control actin organizati

133 ti-leukemic activity in vitro and in vivo by inhibiting leukemia cell proliferation/viability and by

134 at CCDC3 modulates liver lipid metabolism by inhibiting liver de novo lipogenesis as a downstream pla

135 The results showed that inhibiting LKB1 or MARK1 in NSCLC increases the collagen

136 MenA inhibiting, long chain-based compounds were designed, sy

137 lymphedema by promoting tissue fibrosis and inhibiting lymphangiogenesis.

138 Furthermore, inhibiting matrix metalloproteinases in ACM reversed ACM

139 simvastatin may suppress TamR cell growth by inhibiting MCM7 and Rb and subsequently inducing DNA dam

140 the ROS and RNS concentrations in the cancer-inhibiting media.

141 all-molecule inhibitors, we demonstrate that inhibiting MEK1/2, the upstream kinases of ERK1/2 signal

142 , thus reducing MEK1/2 and ERK1/2 signaling, inhibiting melanoma cell growth and inducing apoptosis.

143 to control the fermentation step, instead of inhibiting methanogens using expensive or toxic chemical

144 eutic effect of OEPCs is improved in vivo by inhibiting miR-17.

145 IRP1 protein binds IRE-RNA, inhibiting mRNA activity; Fe(2+) decreases IRE-mRNA/IRP1

146 t stability can be significantly restored by inhibiting mTORC1 or p70S6 kinase (p70S6K), downstream k

147 the N17 represents an attractive target for inhibiting multiple pathways.

148 supporting a cell-intrinsic role of BCAP in inhibiting myeloid proliferation and differentiation.

149 (ROCK) prevented cytoskeletal defects, while inhibiting myosin light chain kinase or phosphorylation

150 Inhibiting myostatin induced a more profound increase in

151 onical NDC80 mRNA expression in cis, thereby inhibiting Ndc80 protein synthesis.

152 ATG16L1 maintains the intestinal barrier by inhibiting necroptosis in the epithelium.

153 -independent contributions by activating or inhibiting neurogenic activity with veratridine and tetr

154 effect on hippocampal proliferative cells by inhibiting neuronal proliferation and triggering the for

155 rd increased glycolysis while simultaneously inhibiting NF-kappaB signaling and apoptosis.

156 primary CD4(+) T cells upon TCR stimulation, inhibiting NF-kappaB signaling via its effects on the Ik

157 complex assembly and SM contraction without inhibiting NM myosin Ser1943 phosphorylation or NM myosi

158 es in the corticosteroid resistance process, inhibiting normal GRalpha nuclear function.

159 embryonic stem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription

160 in which antitumor efficacy has been shown; inhibiting only late NOX activation does not exhibit suc

161 entify claudin-3 as a therapeutic target for inhibiting overactivation of Wnt-signaling to prevent CR

162 se patients, and it is linked to disease, as inhibiting OXPHOS reduces the severity of murine colitis

163 2-dependent NMY-2 in the posterior domain by inhibiting PAR-3 and PAR-6.

164 Inhibiting pathological angiogenesis therefore represent

165 o increased c-Jun N-terminal kinase, thereby inhibiting peroxisome proliferator-activated receptor ga

166 hat H2S activates CFTR in Xenopus oocytes by inhibiting phosphodiesterase activity and subsequent sti

167 nces TRAIL-induced loss of cell viability by inhibiting phosphorylation of Akt and promoting p53 func

168 e of Lowe (OCRL) deficiencies are reduced by inhibiting PI(3)P production, suggesting PI(3)P kinase i

169 e, we report in vitro and in vivo effects of inhibiting PI3Kdelta in APDS.

170 Mechanistically, VEC exerts this effect by inhibiting polycomb protein activity on the specific gen

171 upting actin filament regulation processes - inhibiting polymerization-promoting signaling through se

172 and maintained both flesh and pulp colour by inhibiting polyphenol oxidase (PPO) activity of the both

173 y a key role in PM H(+)-ATPase activation by inhibiting PP2C.D family protein phosphatases.

174 inferior frontal gyrus, often implicated in inhibiting prepotent responses, connected more strongly

175 ontinue to prevail in the poorest countries, inhibiting progress in scaling up and also in achieving

176 Inhibiting progression through mitosis or loss of patter

177 Compound 1 demonstrated efficiency in inhibiting proliferation in tumor cell lines and a rat x

178 ession of virus-specific B cell responses by inhibiting proliferation of germinal center (GC) B cells

179 rk demonstrates anti-tumor effects of 2HG in inhibiting proliferation/survival of FTO-high cancer cel

180 ies resins with therapeutic and biofilm acid-inhibiting properties has the potential to substantially

181 ifferentiation of prostate epithelial cells, inhibiting prostate development.

182 inhibition suppressed GSC growth in part by inhibiting prosurvival AKT/mTOR pathways and stimulating

183 UBE2S at Thr 152, enhancing its stability by inhibiting proteasomal degradation.

184 Inhibiting protein phosphatase-1 through the overexpress

185 The ribosome-inhibiting protein saporin was conjugated to a Siglec-8-

186 Ricin A chain can cause toxicity by inhibiting protein synthesis, and ricin B can bind to th

187 Inhibiting pyramidal neurons by optogenetically activati

188 Removing these cells with a LF and/or inhibiting pyroptosis of the cells can be a new therapeu

189 RKIP transitions from inhibiting Raf-1 to inhibiting G-protein-coupled recepto

190 This procedure eliminates (i) the use of PCR-inhibiting reagents (e.g., chaotropic salts and alcohol)

191 one chaperones increased unwrapping, whereas inhibiting release of paused RNAPII or reducing RNAPII e

192 a, thereby increasing migration velocity and inhibiting reversals within the hermaphrodite uterus.

193 er treatment suppresses viral replication by inhibiting reverse transcriptase, which may restore the

194 Upon inhibiting RNA polymerase II termination via depletion o

195 , depleting neutrophils or Kupffer cells, or inhibiting S100A8/A9 binding to RAGE (using paquinimod),

196 yielded two attractive chemotypes capable of inhibiting S1P formation in cells.

197 nd diversity of fire-dependent ecosystems by inhibiting seed germination or increasing mortality of s

198 ulating astrocyte Shh release was decreased, inhibiting Shh delivery to brain endothelial cells.

199 Improving mitochondrial SIRT3 functions by inhibiting SIRT3 acetylation may offer a new therapeutic

200 Finally, we show that one consequence of inhibiting SPL is intracellular inhibition of histone de

201 stant ovarian cancer cells to PTX and DOX by inhibiting survivin expression.

202 enabling LTM maintenance after retrieval by inhibiting T286 autophosphorylation of alphaCaMKII.

203 residues, including the role of Pro(301) in inhibiting Tau aggregation.

204 itical antagonist of CRC progression through inhibiting TAZ and YAP, effectors of WNT signaling.

205 effects during progressive kidney injury by inhibiting TGF-beta type 1 receptor.

206 ous 2-AG and their actions were prevented by inhibiting the 2-AG-synthesizing enzyme diacylglycerol l

207 f two critical MYC-mediating factors through inhibiting the acetyllysine binding of BRD4 and the kina

208 re vemurafenib sensitivity, reducing or even inhibiting the acquired chemoresistance in melanoma pati

209 -linked polyubiquitination of RIG-I, thereby inhibiting the activation of downstream sensors in the R

210 POP2 also impairs macrophage priming by inhibiting the activation of non-canonical IkappaB kinas

211 rol content in prostate cancer cell lines by inhibiting the activation of sterol regulatory-element b

212 erted these effects by targeting PDE4B, thus inhibiting the activity of mTOR signaling.

213 Inhibiting the activity of Pol III in the gut of adult w

214 lecules or monoclonal antibodies that act by inhibiting the activity of specific proteins that drive

215 tively induces PEL cell cycle arrest through inhibiting the activity of the nuclear factor-kappaB pat

216 cceptance was the most commonly cited factor inhibiting the adoption of ATS, and a variety of technic

217 onstitutive activities of odorant receptors, inhibiting the basal spike firing in olfactory sensory n

218 small membrane protein phospholamban (PLN), inhibiting the cardiac sarco/endoplasmic reticulum calci

219 re internalized by active transport and that inhibiting the caveolae-mediated pathway significantly r

220 osome segregation defects in cancer cells by inhibiting the correction of erroneous KT-MT interaction

221 in low-temperature geochemical environments, inhibiting the development of a conceptual model of U be

222 this protection was completely abolished by inhibiting the dNGIs survival.

223 egulate energy metabolism in mitochondria by inhibiting the electron transfer activity of mitoNEET.

224 L-21 receptor signaling in donor T cells and inhibiting the elimination of thymic ILCs improved thymo

225 cific co-chaperone function of Hsp90 without inhibiting the entire Hsp90 machinery.

226 each chromatographic peak and identify those inhibiting the enzyme activity.

227 Here, we study the effects of inhibiting the ESCRT-associated AAA+ ATPase VPS4 on EV r

228 es and final virus yields of viruses without inhibiting the expression of early to late viral protein

229 hypertension-induced cardiac hypertrophy by inhibiting the expression of ERK pathway.

230 hages (microglia) in WNV-infected SCSC while inhibiting the expression of genes associated with proin

231 he activity of mTOR signaling mainly through inhibiting the expression of PDE4B.

232 may suppress host kynurenine metabolism, by inhibiting the expression of the metabolizing enzyme, ID

233 Inhibiting the fall of plasma FFAs in these mice prevent

234 ts to treat MDR P. aeruginosa, we focused on inhibiting the first committed step in the biosynthesis

235 Inhibiting the formation and release of the invagination

236 Factors inhibiting the formation of high-quality large-scale sup

237 erefore maximizes theoretical capacity while inhibiting the formation of polysulfide intermediates th

238 e retrograde signal decreases ACh release by inhibiting the function of pre-synaptic UNC-2/CaV2 calci

239 xel and promoted apoptosis, thereby potently inhibiting the growth of ABCB1 overexpressing tumors.

240 that ANI-7 is up to 263-fold more potent at inhibiting the growth of breast cancer cell lines (MCF7,

241 Inhibiting the HBP through genetic and chemical methods

242 Selectively inhibiting the individual domains is likely to reduce th

243 vidence with a focus on compounds capable of inhibiting the interaction of RAS proteins with their ef

244 ne, a 3,3-triamine) was superior in terms of inhibiting the migration of L3.6pl cells in vitro.

245 causes developmental arrest in zebrafish by inhibiting the mitochondrial complex I, but it is unknow

246 vide genetic and pharmacologic evidence that inhibiting the N-myristoyltransferase NMT1 suppresses ce

247 PGE2 can block the maturation of IL-1beta by inhibiting the NLRP3 inflammasome in macrophages.

248 onformational selection as the mechanism for inhibiting the nongenomic action of tRXRalpha and provid

249 Inhibiting the nuclear receptor's activity using a chemi

250 g the cell of the amino acid cysteine, or by inhibiting the phospholipid hydroperoxidase glutathione

251 induce IL-1beta mRNA and pro-IL-1beta while inhibiting the production of TNF-alpha.

252 nst DN by increasing glucose metabolic flux, inhibiting the production of toxic glucose metabolites a

253 Major progress has been made clinically in inhibiting the programmed death receptor 1 (PD-1)/PD-L1

254 nly in early and established RA, but also in inhibiting the progression of the disease from arthralgi

255 Most compounds were effective in inhibiting the RA overexpressed hCA IX and XII, with KI

256 reduces the steady-state ATPase activity by inhibiting the rate of phosphate release of beta-cardiac

257 ins," which bind to host chemokines, thereby inhibiting the recruitment of leukocytes to the location

258 This retrograde regulation functions by inhibiting the recruitment of PPARgamma to the regulator

259 een reported as an autophagy-inducing factor inhibiting the replication of pathogens such as HIV, typ

260 Here we challenged rRNA 2'-O-Me globally by inhibiting the rRNA methyl-transferase fibrillarin in hu

261 ADH-41 was also effective at inhibiting the seed-catalyzed aggregation of Abeta proba

262 We find, for example, that inhibiting the set of four kinases AURKB, NEK1, TTK, and

263 Interestingly, inhibiting the TOR signaling pathway rescued the midgut

264 rmation in the bacterium Myxococcus xanthus, inhibiting the transition from growth to development whe

265 sulin-induced AKT1 activation by binding and inhibiting the tumor suppressor DAB2IP (DAB2-interacting

266 nce of either sucrose or salt, we found that inhibiting the VP selectively reduced the elevation in t

267 entifying a cystine-dense peptide capable of inhibiting the YAP:TEAD interaction at the heart of the

268 zed Pt NPs induced nanoparticle aggregation, inhibiting their catalytic activity.

269 uppresses replication of X4 HIV-1 strains by inhibiting their entry.

270 monly activate cellular gene expression, yet inhibiting their recruitment paradoxically reactivates l

271 ers may be important for upcoming complement-inhibiting therapies.

272 ivation and may benefit more from complement-inhibiting therapy than patients with AMD in general.

273 The relative importance of inhibiting these 2 kinases has not been examined despite

274 Inhibiting THIK-1 function pharmacologically or by gene

275 ut reduced after silencing GCS expression or inhibiting this enzyme.

276 suggest that therapeutic strategies aimed at inhibiting this protease-dependent cleavage of Akt may p

277 y and localization and show the potential of inhibiting TLR4-TLR6 dimerization as a treatment of Alzh

278 Inhibiting topoisomerases or depleting histone chaperone

279 BRAF(V600E) Accordingly, the addition of MEK-inhibiting trametinib to BRAF-inhibiting dabrafenib was

280 rotein kinase A (PKA) to accelerate aging by inhibiting transcription factors Msn2/4.

281 the effect of anti-PD-1 antibody therapy on inhibiting tumor growth in the BRAF V600E/PTEN-null mela

282 indicate that HPssCD-HET0016 is effective in inhibiting tumor growth through decreasing proliferation

283 GF), is therefore an attractive strategy for inhibiting tumor growth.

284 sing breast cancer xenografts, significantly inhibiting tumor growth.

285 he exosomal donor cells instead of exosomes, inhibiting tumour progression.

286 nsitive and sorafenib-resistant Huh-7 cells, inhibiting TYRO3/growth arrest specific 6-mediated cance

287 inding unit connected by a linker to a Dicer inhibiting unit.

288 Depleting or inhibiting USP13 sensitizes ovarian cancer cells to cisp

289 Mechanistically, inhibiting VEGFR2 or AMP-activated protein kinase (AMPK)

290 -1 infection through the combined effects of inhibiting viral cDNA production and cytidine-to-uridine

291 HLA-B*14-EL9 is substantially more potent at inhibiting viral replication than HLA-B*14-DA9.

292 is and inhibitory via production of hedgehog-inhibiting vitamin D3 (D3).

293 nal region, which in turn promotes growth by inhibiting Warts.

294 romotes mitotic entry by phosphorylating and inhibiting Wee1.

295 ession, suggesting that Notum acts solely by inhibiting Wg trans-synaptic signaling.

296 ion of the protein CBP with beta-Catenin and inhibiting Wnt-activated genes.

297 nial mouse xenograft models of glioblastoma, inhibiting Wnt5a activity blocked brain invasion and inc

298 Inhibiting Wnt5a in mesenchymal glioblastoma TPC suppres

299 Inhibiting xanthine oxidase, a major reactive oxygen spe

300 a1, abolishing actin stress fiber formation, inhibiting YAP and its target gene expression, with pote