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1 ombination with ciprofloxacin (2.5 x minimum inhibitory concentration).
2 cern the molecular mechanism and the minimum inhibitory concentration.
3 se catalytic site, thus lowering the minimal-inhibitory concentration.
4 ociated with an increased vancomycin minimum inhibitory concentration.
5 well below the protein-binding-adjusted 90% inhibitory concentration.
6 ructurally diverse antibiotics at a range of inhibitory concentrations.
7 where, and when, the drugs are found at sub-inhibitory concentrations.
8 roES overexpression did not increase minimum inhibitory concentrations.
9 he half maximal (IC50) and the minimal (MIC) inhibitory concentrations.
10 types, as well as metadata including minimum inhibitory concentrations.
12 n the MCL cell lines with lower half-maximal inhibitory concentration (0.1-0.5 muM), pevonedistat ind
13 DTG concentrations exceeded the in vitro 50% inhibitory concentration (0.21 ng/mL) by a median of 214
15 O4(-) uptake via hNIS in vitro (half-maximal inhibitory concentration, 0.55-0.56 muM (in comparison w
20 n (geometric mean titres of the half maximum inhibitory concentration: 2688 in the 10 mug group, 1775
21 AP-susceptible Enterococcus faecium (minimum inhibitory concentration, 3 microg/mL) harboring genetic
23 9726 was 35-800-fold higher than the Minimum Inhibitory Concentration 50% (MIC50 values), which indic
24 MAb, IM-CKV063, was highly neutralizing (50% inhibitory concentration, 7.4 ng/ml), demonstrated high-
25 a novel high-affinity radioligand (human 50% inhibitory concentration = 9.6 nM) for the PAM site of m
26 presentation had a 2.01-fold-higher minimum inhibitory concentration (95% CI, 1.39-fold to 2.91-fold
27 bidity detection accuracy of 98.21%, minimum-inhibitory-concentration accuracy of 95.12%, and a drug-
29 that exhibited a marked increase in the 50% inhibitory concentrations against all tested NAIs (827-,
31 P disruption corresponded with lower minimum inhibitory concentrations against the Gram-positive Stap
32 ions for various dosing regimens and minimal inhibitory concentration and calculated the probability
33 ain a vitreous level that exceeds its median inhibitory concentration and can significantly decrease
34 12 resulted in levels above the half-maximal inhibitory concentration and neutralization of VEGF in a
35 istant mutants increase the in vitro minimum inhibitory concentration and the in vivo 99% effective d
36 ding and increased both the in vitro minimum inhibitory concentration and the in vivo effective dose
39 e inhibitors (1) inhibit EBOV infection (50% inhibitory concentration, approximately 0.28 and approxi
42 ill be used, along with the existing minimum inhibitory concentration, as a standard for the in vitro
43 antibiotic against S. constellatus (minimum inhibitory concentration at 90% [MIC90] 0.25 mg/L), and
44 nable in vitro and urinary activity (minimum inhibitory concentration breakpoint </=64 microg/mL) aga
45 and strains with elevated vancomycin minimum inhibitory concentrations, but clinicians should always
46 ther increased oseltamivir and peramivir 50% inhibitory concentrations by 790- and >5000-fold, respec
47 oncentrations exceeding 10 times the minimum inhibitory concentration completely inhibited the growth
48 t fecal concentrations greater than parasite inhibitory concentrations correlate best with effective
49 odels confirmed that a high triazole minimal inhibitory concentration corresponded with triazole trea
52 at inhibiting FAAH, Cox-1, and Cox-2 (median inhibitory concentration: FAAH, 0.031 +/- 0.002 microM;
53 hour concentration-time curve to the minimum inhibitory concentration (fAUC/MIC) was found to be the
55 by in vitro IC50 and IC80 values (50 and 80% inhibitory concentrations) figure prominently into the s
58 ation spent over 64 mg/L (4-fold the minimal inhibitory concentration for Pseudomonas aeruginosa) wer
59 ease of >3 doubling dilutions in the minimum inhibitory concentration for third-generation cephalospo
60 concentrations and exceeded the in vitro 50% inhibitory concentration for wild-type HIV (0.2 ng/mL),
61 SF was >0.51 ng/mL (proposed CSF 50% maximal inhibitory concentration for wild-type virus) in all sub
62 l derived from the clay exceeded the minimum inhibitory concentrations for E. coli under acidic condi
64 t drug concentrations inside caseum and high inhibitory concentrations for this bacterial subpopulati
66 istin susceptibility by reducing the minimum inhibitory concentration from 8 to 0.5 mug/ml, 4-fold be
67 ositive predictive value compared to minimum inhibitory concentrations generated by commercial method
68 igecycline therapy given tigecycline minimum inhibitory concentration greater than 2 mg/L compared wi
69 ine in the subgroup with tigecycline minimum inhibitory concentration greater than 2 mg/L compared wi
72 solates clinically resistant to AZM (minimum inhibitory concentration >/=16 microg/mL) was also signi
73 hogen or S. aureus with a vancomycin minimum inhibitory concentration >1 microg/mL, however, had high
74 ortion of isolates with a penicillin minimal inhibitory concentration >2 microg/mL decreased signific
78 sistance in MRSA and increase in the minimum inhibitory concentrations (>1 or 2 microg/mL); however,
79 with high but susceptible vancomycin minimum inhibitory concentrations have been associated with addi
81 or estimating the potency [e.g. half-maximum inhibitory concentration (IC) known as IC50] of anti-can
82 ions and displayed significant shifts in 50% inhibitory concentrations (IC(50)s), characteristic of r
83 se is inhibited by sulfide with half-maximal inhibitory concentration IC50 = 1.1 +/- 0.1 muM, under i
84 ent genotypes, and showed differences in 50% inhibitory concentration (IC50 ) correlating with clinic
87 viral entry process with a submicromolar 50% inhibitory concentration (IC50) (IC50 = 0.61 +/- 0.23 mu
89 eukemia cell lines revealed the half maximal inhibitory concentration (IC50) for inhibiting FLT3 auto
91 y (ORAC) assays with a measured half-maximal inhibitory concentration (IC50) for the best case of 1.5
92 oduced measurable cytotoxicity [half maximal inhibitory concentration (IC50) in MMP assay/IC50 in via
95 was in good agreement with the half maximal inhibitory concentration (IC50) of 0.018 nM determined f
97 a dose-dependent manner, with a half maximal inhibitory concentration (IC50) of 0.087 +/- 0.012 mg of
99 significantly greater fold increases in 50% inhibitory concentration (IC50) of EFV than viruses carr
101 an and rat P2X7R orthologs, the half maximal inhibitory concentration (IC50) of JNJ-54173717 was 4.2
102 h isoeugenol showing the lowest half-maximal inhibitory concentration (IC50) values of mycelium growt
103 on of 11, all complexes exhibited 50% growth inhibitory concentration (IC50) values that were less th
104 of kelch13 mutations, higher piperaquine 50% inhibitory concentration (IC50) values, and lower mefloq
105 ing antioxidant activities, the half maximal inhibitory concentration (IC50) was 215.86 mug/ml and Tr
107 highest increase in oseltamivir half-maximal inhibitory concentration (IC50), and E119D conferred the
108 ation constant, time to protein-adjusted 50% inhibitory concentration (IC50), and week 5 nevirapine l
109 tives, were identified, and the half-maximal inhibitory concentration (IC50), inhibition constant (K(
110 h mitochondrial O2 consumption [half maximal inhibitory concentration (IC50): 3.8muM] and ATP synthes
113 des, LPVP and MPVQA, had DPP-IV half maximal inhibitory concentrations (IC50) of 87.0+/-3.2 and 93.3+
114 ls significantly decreased the fifty percent inhibitory concentrations (IC50) of chemotherapeutic dru
116 ld higher IFNbeta (P < 0.00001) half-maximal inhibitory concentrations (IC50) than did donor isolates
120 by SIV-infected macaque plasma samples (50% inhibitory concentration [IC50] < 10(-5)) and monoclonal
122 und to GRPR with high affinity (range of 50% inhibitory concentration [IC50] values, 0.3 nM [SARNC5]
123 issue-independent (maternal BBB half-maximal inhibitory concentration [IC50], 5.67 +/- 1.07 muM, vs.
124 azyl (DPPH) radical quenching potential (50% inhibitory concentration, IC50 approximately 0.59mg/mL)
126 anti-Plasmodium properties with half-maximal inhibitory concentrations (IC50s) of 2.9 +/- 2.4, 10.7 +
127 iations (CNVs) with in-vitro piperaquine 50% inhibitory concentrations (IC50s), and tested whether th
128 10-50% of HIV-1 isolates inefficiently (80% inhibitory concentration (IC80) > 5 mug ml(-1)), suggest
129 mosomes were associated with piperaquine 90% inhibitory concentrations (IC90) in a genome-wide analys
130 ciation (P < .05) with either cytarabine 50% inhibitory concentration in leukemia cells or clinical r
132 ic and drug-resistant bacteria, with minimal inhibitory concentrations in a sub-micromolar range.
133 potent compound displayed micromolar minimal inhibitory concentrations in different Gram-negative and
134 after gel application and remained above 95% inhibitory concentrations in rectal fluids at 24 hours.
136 ides attached to an acyl chain, have minimal inhibitory concentrations in the micromolar range agains
137 and ethyl ester prodrug forms showed minimum inhibitory concentrations in the range of 21-43 mug/mL a
139 ibited good activity as well as a fractional inhibitory concentration index (FICI) of 0.1 with methic
140 ntly synergizes with methicillin (fractional inhibitory concentration index = 0.25) and is protective
141 ivity is defined analogously to a fractional inhibitory concentration index of unity, and the extent
144 bility testing, and determination of minimum inhibitory concentration is conventionally performed by
145 copies per mL and a BMS-626529 half-maximum inhibitory concentration lower than 100 nmol/L were rand
146 susceptible breakpoint of cefepime (minimum inhibitory concentration </= 8 mug/mL), cefepime definit
148 hereas 221-7 was borreliacidal (half maximal inhibitory concentration, < 1 nM) against B. burgdorferi
150 istance, which is measured using the minimum inhibitory concentration metric, tolerance and persisten
151 ates, there were 10 with ceftriaxone minimum inhibitory concentration (MIC) >/=0.06 mg/L and azithrom
152 nd 11.8% (group B) of patients had a minimum inhibitory concentration (MIC) >2 mug/mL to penicillin.
153 ore potent antimicrobial agents [VRE minimum inhibitory concentration (MIC) = 0.01-0.005 mug/mL] with
155 fungal activity was studied, and the minimal inhibitory concentration (MIC) and minimal fungicidal co
156 vity was determined by measuring the minimum inhibitory concentration (MIC) and minimum bactericidal
160 PPMOs were evaluated in vitro using minimum inhibitory concentration (MIC) and viability assays, and
161 ow classic metrics like the IC50 and minimal inhibitory concentration (MIC) are dubious proxies for u
162 tibacterial activities, lowering the minimum inhibitory concentration (MIC) by more than one order of
163 method for telavancin, resulting in minimum inhibitory concentration (MIC) determinations that are m
164 rmore, sulphated PEPS had the lowest minimum inhibitory concentration (MIC) for E. coli ATCC 25922, a
166 resulted in a 2-fold increase in the minimal inhibitory concentration (MIC) for the hybrid, while mox
169 is unclear whether higher-vancomycin minimum inhibitory concentration (MIC) is associated with mortal
171 Compound 1f was most potent with a minimal inhibitory concentration (MIC) of 12.5 mug/mL and an Mtb
173 osis; the most potent compound had a minimum inhibitory concentration (MIC) of 52 nM and was not cyto
175 nd monthly for 3 months by change in minimal inhibitory concentration (MIC) of culture isolates was s
177 antibiotic concentrations above the minimum inhibitory concentration (MIC) of the pathogen at both 5
179 voriconazole at 1x, 10x, 25x, or 50x minimum inhibitory concentration (MIC) or amphotericin B at 0.25
180 ells in 60 min and susceptibility at minimum inhibitory concentration (MIC) range of 6.25-12.5 mug/mL
181 fficacy was linked to the AUC0-24 to minimum inhibitory concentration (MIC) ratio (r(2) = 0.98).
183 nd correlated treatment outcome with minimum inhibitory concentration (MIC) results and the presence
185 A remarkable 1000-fold decrease in minimum inhibitory concentration (MIC) value is observed for uro
186 ested fungal strains, with excellent minimum inhibitory concentration (MIC) values against non-albica
187 ng Mycobacterium tuberculosis , with minimum inhibitory concentration (MIC) values lower than those o
191 ctive against Staphylococcus aureus [minimal inhibitory concentration (MIC)(90) approximately 0.25 mi
192 igma correlates not with a peptide's minimum inhibitory concentration (MIC), but rather its ability t
196 sed on 735 literature data points of minimum inhibitory concentrations (MIC) of Plantae, Bacteria, an
198 ell Mtb activity varied greatly with minimum inhibitory concentrations (MIC) ranging from 0.78 to >10
199 of zingerone (2b-2e) exhibited lower minimum inhibitory concentrations (MIC) values than zingerone (2
200 eference and wild bacterial strains, minimal inhibitory concentrations (MIC) were achieved in a conce
201 s were more likely to have meropenem minimum inhibitory concentrations (MICs) >/=16 microg/mL, while
202 l demonstrated elevated azithromycin minimum inhibitory concentrations (MICs) >256 mug/mL and elevate
203 ever, we additionally found that the minimum inhibitory concentrations (MICs) against fluoroquinolone
206 -kill kinetic assay was performed at minimum inhibitory concentrations (MICs) in all planktonic strai
207 t E. faecium strains with daptomycin minimum inhibitory concentrations (MICs) in the higher end of su
208 ituted quinazoline-2,4-diamines with minimum inhibitory concentrations (MICs) in the low micromolar r
210 ns nontoxic to mammalian cells), the minimum inhibitory concentrations (MICs) of imipenem against cli
211 phyte, Chlamydomonas reinhardtii, to minimum inhibitory concentrations (MICs) of single-herbicide mod
213 o produce a wide range of ethambutol minimal inhibitory concentrations (MICs) that depended on mutati
219 xchange mediated by mouse pendrin with a 50% inhibitory concentration of 1-3 microM, without affectin
220 ith a KD of 76 nM against BioA and a minimum inhibitory concentration of 1.7 muM (0.6 mug/mL) against
221 teria monocytogenes: cIsf pool had a minimum inhibitory concentration of 10microg/ml prenylated compo
222 One of the T inkin isolates had a minimal inhibitory concentration of 2 mg/L against amphotericin
225 this blocking agent revealed a half maximal inhibitory concentration of 40 nM which is comparable to
229 Ga-HZ220 had a lower affinity for GRPr (inhibitory concentration of 50% [IC50], 21.4 +/- 7.4 nM)
234 st and second half of the study, the minimal inhibitory concentration of antibiotics required to inhi
235 to CS extract 0.2-0.75% with a half-maximal inhibitory concentration of approximately 0.5%) led to i
237 rary that is capable of lowering the minimum inhibitory concentration of beta-lactam antibiotics by u
238 uced cell proliferation and reduced the IC50 inhibitory concentration of chemotherapeutic drugs in vi
242 ns of drug 100-fold greater than the minimal inhibitory concentration of most bacteria including MDRO
244 rgeted nanospheres achieved the half maximal inhibitory concentration of PTX on SUM159 cells at a 5-1
247 pathogenic Aspergillus spp. revealed minimal inhibitory concentrations of </=0.06 microg/mL-greater p
249 on centre photocurrents yielded half maximal inhibitory concentrations of 208nM and 2.1microM for ter
252 cterial susceptibility testing shows minimum inhibitory concentrations of 80 mg/mL against a model Es
257 the concentration will persist above minimum inhibitory concentrations of Candida species for several
266 hrough the estimation of amoxicillin minimum inhibitory concentration on a subset of 990 mutants carr
269 132 and 1,782 h.mg/L, and AUC(0-24h)/minimum inhibitory concentration ratios of 528 and 7129, respect
270 010), with a bimodal distribution of minimum inhibitory concentration recorded between 2009 and 2010.
271 isolates from 1990 through 2001, the minimal inhibitory concentration required to inhibit 90% of isol
272 to vancomycin and linezolid, higher minimal inhibitory concentration required to inhibit 90% of isol
274 culture-based antibiotic sensitivity minimum inhibitory concentration, sociodemographic and behaviora
275 e associated with a 3.48-fold-higher minimum inhibitory concentration than those isolates that were n
277 time that faropenem persisted above minimum inhibitory concentration (TMIC) on the moxifloxacin-line
278 .4-12]; p<0.0001) and higher piperaquine 50% inhibitory concentration (triple mutant 34 nM [28-41]; n
279 vels far exceeding the cellular half maximal inhibitory concentration values (>100,000-fold), and apt
280 ted strains of M. tuberculosis, with minimum inhibitory concentration values as low as 0.03 muM (0.01
281 d sensitivity to dasatinib with half maximal inhibitory concentration values below 20 nM was detected
282 ed with significantly higher PI half-maximum inhibitory concentration values compared with other mole
283 :blood penetration ratios were above the 50% inhibitory concentration values in almost 100% of cases.
289 Treatment response and echinocandin minimum inhibitory concentrations varied among specific FKS muta
292 e consistently infected, the average minimum inhibitory concentration was 0.26 microg/mL for azithrom
294 he geometric mean titres of the half maximum inhibitory concentration were 8745 for the 10 mug group,
299 ncentrations divided by in vitro 50% and 95% inhibitory concentrations) were compared among different
300 inoglycosides as measured by reduced minimum inhibitory concentrations, whereas GroEL/GroES overexpre
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