ライフサイエンスコーパス: inhibitory synaptic transmission

1 ard enabling the study of diseases affecting inhibitory synaptic transmission.

2 us systems, where they mediate rapid, mostly inhibitory synaptic transmission.

3 piking, as well as control of excitatory and inhibitory synaptic transmission.

4 eover, their occurrence and timing relied on inhibitory synaptic transmission.

5 tive splicing of a host of genes involved in inhibitory synaptic transmission.

6 aptic sites to alter GABAA receptor-mediated inhibitory synaptic transmission.

7 monstrate an absolute requirement for phasic inhibitory synaptic transmission.

8 tic sites to alter GABA(A) receptor-mediated inhibitory synaptic transmission.

9 cts are generally viewed in terms of altered inhibitory synaptic transmission.

10 uced after dark rearing and also by blocking inhibitory synaptic transmission.

11 antagonists to block all fast excitatory and inhibitory synaptic transmission.

12 but dispensable for both AMPAR-mediated and inhibitory synaptic transmission.

13 leads to increased excitatory and decreased inhibitory synaptic transmission.

14 e receptors (GlyRs), which both mediate fast inhibitory synaptic transmission.

15 thereby affect the polarity and efficacy of inhibitory synaptic transmission.

16 ontrast PGE2 affected neither excitatory nor inhibitory synaptic transmission.

17 citatory synapses produces minimal change in inhibitory synaptic transmission.

18 ns and is required for normal excitatory and inhibitory synaptic transmission.

19 HDAC2 KD reduced, whereas HDAC2 OE enhanced, inhibitory synaptic transmission.

20 of epilepsy, probably due to impairments in inhibitory synaptic transmission.

21 neurons, leading to significant reduction of inhibitory synaptic transmission.

22 e recycling which impaired the efficiency of inhibitory synaptic transmission.

23 GABA(A) receptors mediate fast inhibitory synaptic transmission.

24 that ClC-2 reduces spiking independently of inhibitory synaptic transmission.

25 input patterns in the presence or absence of inhibitory synaptic transmission.

26 that mice lacking IgSF21 exhibit deficits in inhibitory synaptic transmission.

27 -1beta, IL-6, and TNFalpha on excitatory and inhibitory synaptic transmission.

28 atory synaptic transmission or by decreasing inhibitory synaptic transmission.

29 re generally known to suppress excitatory or inhibitory synaptic transmission.

30 cally produces a long-lasting enhancement of inhibitory synaptic transmission.

31 t pulses were used to induce modification of inhibitory synaptic transmission.

32 ion and major defects in excitatory, but not inhibitory, synaptic transmission.

33 ) subunits underlies the variability of fast inhibitory synaptic transmission; alteration of specific

34 stnatal day 7 display a lasting reduction in inhibitory synaptic transmission, an increase in excitat

35 prived region characterized by a decrease in inhibitory synaptic transmission and a normal hearing re

36 tus alter the balance between excitatory and inhibitory synaptic transmission and associated synaptic

37 ate whether and how resveratrol alters basal inhibitory synaptic transmission and cocaine-induced inh

38 the VTA shifts the balance of excitatory and inhibitory synaptic transmission and decreases dopamine

39 ic acid (GABA) type A receptors mediate fast inhibitory synaptic transmission and have been implicate

40 PARs, resulting in a homeostatic decrease in inhibitory synaptic transmission and increased intrinsic

41 by rapid GABA transients present during fast inhibitory synaptic transmission and is critical to unde

42 naptic densities of neurons, but its role in inhibitory synaptic transmission and plasticity is unkno

43 ing evidence indicates that GABA acts beyond inhibitory synaptic transmission and regulates the devel

44 innervation by basket interneurons, enhanced inhibitory synaptic transmission, and earlier onset of o

45 ribute to the balance between excitatory and inhibitory synaptic transmission, and electrical activit

46 did not significantly enhance GABAA-mediated inhibitory synaptic transmission, and GABA receptor anta

47 accompanied by alterations in excitatory and inhibitory synaptic transmission, and intrinsic excitabi

48 accompanied by alterations in excitatory and inhibitory synaptic transmission, and intrinsic excitabi

49 (SynII) gene deletion produces a deficit in inhibitory synaptic transmission, and this defect is tho

50 e mechanisms of depression of excitatory and inhibitory synaptic transmission appear to be different.

51 ity-dependent bidirectional modifications of inhibitory synaptic transmission are attributable to bid

52 d this idea by measuring changes to cortical inhibitory synaptic transmission as adult gerbils progre

53 TPMPA reduced inhibitory synaptic transmission at interneurone-Purkinj

54 out how endogenous NO affects excitatory and inhibitory synaptic transmission at the spinal level.

55 Indeed, the differences in inhibitory synaptic transmission between Fmr1 KO and wil

56 on was still dependent, at least in part, on inhibitory synaptic transmission, but spatiotemporal asp

57 erneurones could contribute to depression of inhibitory synaptic transmission by activation of GABAB

58 acitance recordings to unravel mechanisms of inhibitory synaptic transmission by AIIs.

59 neuronal Cl(-), which is essential for fast inhibitory synaptic transmission by GABA and glycine in

60 We found no increase in spontaneous inhibitory synaptic transmission by hCSF, indicating a d

61 trocytes modulate spontaneous excitatory and inhibitory synaptic transmission by increasing the proba

62 de evidence that resveratrol modulates basal inhibitory synaptic transmission, cocaine-induced synapt

63 inhibitory synapses, together with enhanced inhibitory synaptic transmission due to reduced GABA(A)R

64 nstem slices, OXT perfusion had no effect on inhibitory synaptic transmission; following exposure to

65 These significant differences in inhibitory synaptic transmission form an important basis

66 present study dissected fast excitatory and inhibitory synaptic transmission from the VTA to NAc MSN

67 Abnormalities in inhibitory synaptic transmission have been associated wi

68 cannabinoid-mediated long-term depression of inhibitory synaptic transmission (I-LTD) in the ventral

69 obutyric acid (GABA(A)) receptor and enhance inhibitory synaptic transmission in a manner similar to

70 that Ca2+-permeable AMPARs and CaN regulate inhibitory synaptic transmission in a novel plasticity p

71 this issue, we have assessed excitatory and inhibitory synaptic transmission in acute hippocampal sl

72 rate significant physiological impairment in inhibitory synaptic transmission in experimental cortica

73 TA-associated inhibitory synaptic transmission in Fmr1 KO mice was als

74 Here, we show that E2 rapidly suppresses inhibitory synaptic transmission in hippocampal CA1.

75 trocytes in activity-dependent modulation of inhibitory synaptic transmission in hippocampal slices.

76 GABAA receptor (GABAAR)-mediated current and inhibitory synaptic transmission in medium spiny neurons

77 cterize the effects of N2O on excitatory and inhibitory synaptic transmission in microcultures of rat

78 ceptor activation suppresses the efficacy of inhibitory synaptic transmission in NAc by increasing th

79 rovide a novel and powerful form of feedback inhibitory synaptic transmission in one class of cortica

80 123 despite a nearly complete suppression of inhibitory synaptic transmission in Purkinje cells by th

81 Our results show that inhibitory synaptic transmission in Purkinje cells is ne

82 d-gated ion channel superfamily that mediate inhibitory synaptic transmission in the adult central ne

83 Glycine receptors (GlyRs) contribute to fast inhibitory synaptic transmission in the brain stem and s

84 cid type A receptors (GABAA-Rs) mediate fast inhibitory synaptic transmission in the brain.

85 he GluR5 subunit have been shown to modulate inhibitory synaptic transmission in the CA1 region of th

86 found that at KOR signaling robustly reduced inhibitory synaptic transmission in the CeA to BNST path

87 ptors (GABA(A)-Rs) mediate the bulk of rapid inhibitory synaptic transmission in the central nervous

88 The GABRB2 mediates the fastest inhibitory synaptic transmission in the central nervous

89 protein-coupled receptors that mediate slow inhibitory synaptic transmission in the central nervous

90 opic GABA(B) receptors is essential for slow inhibitory synaptic transmission in the CNS, and disrupt

91 ulness as a novel drug target for modulating inhibitory synaptic transmission in the CNS.

92 (KACh) channels are key determinants of the inhibitory synaptic transmission in the heart.

93 Inhibitory synaptic transmission in the hippocampus in m

94 at cause a selective presynaptic increase in inhibitory synaptic transmission in the hippocampus that

95 eceptor agonists have been shown to modulate inhibitory synaptic transmission in the hippocampus, but

96 for the synaptic localization of GABAARs and inhibitory synaptic transmission in the hippocampus.

97 ABAARs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain.

98 is essential for Cl(-) homeostasis and fast inhibitory synaptic transmission in the mature CNS.

99 lity and in the modulation of excitatory and inhibitory synaptic transmission in the medulla oblongat

100 and amphetamine depress both excitatory and inhibitory synaptic transmission in the NAc by a presyna

101 Thus, DA appears to depress inhibitory synaptic transmission in the NAc by reducing

102 ermine if KA receptor activation could alter inhibitory synaptic transmission in the NAcc as it has b

103 xcitatory synaptic transmission and suppress inhibitory synaptic transmission in the pain circuits.

104 Corticosterone application attenuated inhibitory synaptic transmission in the PL via cannabino

105 inoid-dependent effects of corticosterone on inhibitory synaptic transmission in the rat PL were dete

106 e-sensitive glycine receptor (GlyR) mediates inhibitory synaptic transmission in the spinal cord and

107 recently-described nicotinic enhancement of inhibitory synaptic transmission in the spinal cord dors

108 These results suggest that opioids inhibit inhibitory synaptic transmission in the STN through the

109 n of the normal developmental progression of inhibitory synaptic transmission in Ts65Dn mice at a cri

110 and is known to reduce excitatory (but also inhibitory) synaptic transmission in many CNS areas, lea

111 With inhibitory synaptic transmission intact, the maximum fir

112 Because inhibitory synaptic transmission is a major mechanism of

113 The novel, late, NPY-mediated increase of inhibitory synaptic transmission is caused by modulation

114 Furthermore, gain modulation by inhibitory synaptic transmission is disabled in both aud

115 Inhibitory synaptic transmission is known to play an imp

116 ed mTOR alters the balance of excitatory and inhibitory synaptic transmission, leading to hippocampal

117 Inhibitors of excitatory and inhibitory synaptic transmission made spike discharges m

118 These data suggest that increased inhibitory synaptic transmission may contribute to human

119 at changes in VTA-to-NAc fast excitatory and inhibitory synaptic transmissions may contribute to coca

120 nnels in modulating the action of ethanol on inhibitory synaptic transmission mediated via GABAA rece

121 unted dopamine response was due to increased inhibitory synaptic transmission onto dopamine neurons.

122 Patch-clamp recordings revealed increased inhibitory synaptic transmission onto IL projection neur

123 in postnatal development does not rejuvenate inhibitory synaptic transmission or facilitate rapid ocu

124 not accompanied by lasting changes in either inhibitory synaptic transmission or somatic excitability

125 t BDNF expression controls the plasticity of inhibitory synaptic transmission particularly when recov

126 Inhibitory synaptic transmission plays an important role

127 IPSCs, or disinhibition, in that blockade of inhibitory synaptic transmission prevents the effect of

128 However, whether BDNF modulates inhibitory synaptic transmission remains to be firmly es

129 midal cells but does not alter excitatory or inhibitory synaptic transmission, responses thought to b

130 onse to dark exposure is the rejuvenation of inhibitory synaptic transmission, resulting in a decreas

131 ich could be important for the regulation of inhibitory synaptic transmission.SIGNIFICANCE STATEMENT

132 ppressed binge alcohol drinking by enhancing inhibitory synaptic transmission specifically in CRF neu

133 pposite effects to their parent molecules on inhibitory synaptic transmission, suggest that alteratio

134 This imbalance reflects a deficit in inhibitory synaptic transmission that appears to be seco

135 y visual cortex enhances both excitatory and inhibitory synaptic transmission, through the activation

136 llowing a neuron to modulate the strength of inhibitory synaptic transmission to its changing require

137 o-photon glutamate uncaging, which preserves inhibitory synaptic transmission, to demonstrate that so

138 shifting the balance between excitatory and inhibitory synaptic transmission toward inhibition.

139 encoded the strength of synaptic input when inhibitory synaptic transmission was blocked.

140 synaptic transmission, because no change in inhibitory synaptic transmission was observed in the hip

141 oundly affected in these neurons, as well as inhibitory synaptic transmission, we found little pertur

142 Instead, stimulation produced GABA-mediated inhibitory synaptic transmission, which suppressed the f

143 -deficient mice are ameliorated by enhancing inhibitory synaptic transmission with a GABAAR agonist.

144 l changes were accompanied by an increase in inhibitory synaptic transmission with no apparent effect

145 ATP activates presynaptic P2X2Rs to regulate inhibitory synaptic transmission within the SCN and that