ライフサイエンスコーパス: inosine monophosphate

1 functional reaction toward the production of inosine monophosphate.

2 nce of several umami (uridine monophosphate, inosine monophosphate, adenosine, and guanosine) and kok

3 le in the formation of the key intermediates inosine monophosphate and AMP involved in the synthesis

4 carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase (ATIC) and thereby

5 le carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) is responsib

6 le carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) is responsib

7 the bifunctional enzyme AICAR transformylase/inosine monophosphate cyclohydrolase (ATIC).

8 The inosine monophosphate cyclohydrolase (IMPCH) component (

9 arboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, and exi

10 -4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase, Steps 9 and 10), w

11 cophenolic acid (MPA), a potent inhibitor of inosine monophosphate dehydrogenase (IMPD), derived from

12 Inosine monophosphate dehydrogenase (IMPDH) catalyzes th

13 Inosine monophosphate dehydrogenase (IMPDH) controls a k

14 Interindividual variation in inosine monophosphate dehydrogenase (IMPDH) enzyme activ

15 The guanine nucleotide biosynthetic enzyme inosine monophosphate dehydrogenase (IMPDH) forms octame

16 e cloned and characterized the gene encoding inosine monophosphate dehydrogenase (IMPDH) from Arabido

17 e cloned and characterized the gene encoding inosine monophosphate dehydrogenase (IMPDH) from Pyrococ

18 MPA is a potent inosine monophosphate dehydrogenase (IMPDH) inhibitor bu

19 ted that mycophenolic acid (MPA), a specific inosine monophosphate dehydrogenase (IMPDH) inhibitor th

20 Inosine monophosphate dehydrogenase (IMPDH) is a rate-li

21 Inosine monophosphate dehydrogenase (IMPDH) is a target

22 The enzyme inosine monophosphate dehydrogenase (IMPDH) is responsib

23 uanine nucleotide negatively regulates yeast inosine monophosphate dehydrogenase (IMPDH) mRNA synthes

24 guanine nucleotide pools after inhibition of inosine monophosphate dehydrogenase (IMPDH) potently inh

25 The inosine monophosphate dehydrogenase (IMPDH) protein GuaB

26 is carried out by two isoforms of the enzyme inosine monophosphate dehydrogenase (IMPDH) that are cat

27 e-MAD, was found to be a potent inhibitor of inosine monophosphate dehydrogenase (IMPDH) type II (Ki

28 competitive inhibitor, mycophenolic acid, to inosine monophosphate dehydrogenase (IMPDH) were measure

29 Inosine monophosphate dehydrogenase (IMPDH), a key enzym

30 We recently reported that Inosine Monophosphate Dehydrogenase (IMPDH), a rate-limi

31 MPA selectively inhibits inosine monophosphate dehydrogenase (IMPDH), a rate-limi

32 Inosine monophosphate dehydrogenase (IMPDH), a rate-limi

33 dinucleotide (BAD) are potent inhibitors of inosine monophosphate dehydrogenase (IMPDH), the corresp

34 tem and hypoxanthine require the activity of inosine monophosphate dehydrogenase (IMPDH), the rate-li

35 ave been prepared as potential inhibitors of inosine monophosphate dehydrogenase (IMPDH).

36 synthesized as potential inhibitor of human inosine monophosphate dehydrogenase (IMPDH).

37 nockdown of one of the two known isoforms of inosine monophosphate dehydrogenase (IMPDH-1) is suffici

38 ose of this study was to investigate retinal inosine monophosphate dehydrogenase 1 (IMPDH1) transcrip

39 strated a 6-fold reduction in one candidate, inosine monophosphate dehydrogenase 1 (IMPDH1; EC 1.1.1.

40 Antibodies to inosine monophosphate dehydrogenase 2 (IMPDH2) and cytid

41 Inhibitors of the enzyme inosine monophosphate dehydrogenase augmented both IFN-d

42 quantitation of cancer-associated proteins (inosine monophosphate dehydrogenase II, vascular endothe

43 s in the region of the phthalide ring of the inosine monophosphate dehydrogenase inhibitor mycophenol

44 erimepodib (MMPD) is an orally administered, inosine monophosphate dehydrogenase inhibitor that has s

45 amycin [mTOR]) and mycophenolate mofetil (an inosine monophosphate dehydrogenase inhibitor).

46 y)adenine)], alone or in combination with an inosine monophosphate dehydrogenase inhibitor, reduced H

47 BAD inhibits inosine monophosphate dehydrogenase type I (IC50 = 0.78

48 s to determine the frequency and spectrum of inosine monophosphate dehydrogenase type I (IMPDH1) muta

49 ere-associated protein E (Cenpe), Gpr49, and inosine monophosphate dehydrogenase type II] with previo

50 of pharmaceutical interest: p38 MAP kinase, inosine monophosphate dehydrogenase, and HIV protease.

51 itro inhibition of the pharmacologic target, inosine monophosphate dehydrogenase, is dependent on fre

52 henolic acid (MPA), a selective inhibitor of inosine monophosphate dehydrogenase, is the active agent

53 rs the parasite susceptible to inhibition of inosine monophosphate dehydrogenase, the rate-limiting e

54 it lymphocyte proliferation by inhibition of inosine monophosphate dehydrogenase.

55 a potent and specific inhibitor of mammalian inosine-monophosphate dehydrogenases (IMPDH); most micro

56 Inosine monophosphate enhanced taste cell responses to L

57 this goal, we report the use of 5'-O-(1-thio)inosine monophosphate (IMP alphaS) in a nucleotide analo

58 zwf- cells showed that the concentrations of inosine monophosphate (IMP) and uridine monophosphate (U

59 Although inosine monophosphate (IMP) cannot be detected in crude

60 oxamide ribonucleotide (FAICAR) synthase and inosine monophosphate (IMP) cyclohydrolase activity.

61 Inosine monophosphate (IMP) dehydrogenase 2 (IMPDH2) is

62 al enzyme that catalyzes steps 2, 3 and 5 of inosine monophosphate (IMP) synthesis.

63 The enzyme catalyzes the oxidation of inosine monophosphate (IMP) to xanthosine monophosphate

64 ) and its enzymatic activity (EC) generating inosine monophosphate (IMP) were identified with transcr

65 amic properties of binding of the substrate, inosine monophosphate (IMP), and the uncompetitive inhib

66 sphate (ADP), adenosine monophosphate (AMP), inosine monophosphate (IMP), inosine (Ino) and hypoxanth

67 res 10 enzymatic steps for the production of inosine monophosphate (IMP).

68 te (MSG), monopotassium glutamate (MPG), and inosine monophosphate (IMP)] taste as well.

69 Incorporation of inosine monophosphate inhibited next nucleotide addition

70 deaminase (ADA), adenosine kinase (AK), and inosine monophosphate-specific cytosolic 5'-nucleotidase

71 al steps from phosphoribosylpyrophosphate to inosine monophosphate were recently shown to associate i

72 cleosides and nucleotides (e.g., inosine and inosine monophosphate) were also found to be transformed