ライフサイエンスコーパス: insensitivity

1 n, inhibition by extracellular Na(+), and pH-insensitivity).

2 ing from neuropathic pain to congenital pain insensitivity.

3 that could be responsible for glucocorticoid insensitivity.

4 4%) and show glucose intolerance and insulin insensitivity.

5 fundamentally restricted due to its inherent insensitivity.

6 eus to cooperate with tubulin towards taxane insensitivity.

7 besity arises as a result of leptin receptor insensitivity.

8 eased HAT activity generating glucocorticoid insensitivity.

9 ring oxidative stress-induced glucocorticoid insensitivity.

10 ion mutation in PRLR, resulting in prolactin insensitivity.

11 , clinically characterized by glucocorticoid insensitivity.

12 ize type-B ARR proteins leading to cytokinin insensitivity.

13 s growth attenuation and growth hormone (GH) insensitivity.

14 ing to C. glabrata may be the reason for its insensitivity.

15 resistant pathways using our ASM model of GC insensitivity.

16 ds, and oxidative stress contributes to this insensitivity.

17 utation, R405S, that caused partial androgen insensitivity.

18 -mediated inflammation and/or corticosteroid insensitivity.

19 y cultivation as a result of its photoperiod insensitivity.

20 t alternative mechanisms underlie bortezomib insensitivity.

21 compromising Ca(2+)/Mg(2+) selectivity or pH insensitivity.

22 reduced bone growth and growth hormone (GH) insensitivity.

23 med to identify the molecular basis for this insensitivity.

24 stent with clinical stage 3 partial androgen insensitivity.

25 aB (NF-kappaB) signaling pathway) exhibit GH insensitivity.

26 cardiac contractile dysfunction and inotrope insensitivity.

27 androgen, glucocorticoid and/or progesterone insensitivity.

28 ression activity and promotes corticosteroid insensitivity.

29 tion alleles that resulted in complete touch insensitivity.

30 ion of FOXM1 may contribute to anti-estrogen insensitivity.

31 onstrated that Rg1 attenuated UVB-induced GC insensitivity.

32 and also reversed CSE-induced corticosteroid insensitivity.

33 he presence of a water molecule which ensure insensitivity.

34 may, in turn, contribute to further steroid insensitivity.

35 ion being associated with relative abatacept insensitivity.

36 variation at CRY2 underlies this temperature insensitivity across several traits.

37 at constitutively express SUB1A displayed GA insensitivity and abscisic acid hypersensitivity.

38 Insulin insensitivity and adipokine abnormalities (the hallmarks

39 ouble mutant that exhibits complete ethylene insensitivity and confirms that these two genes act redu

40 activity, and noxy2-2, which shows oxylipin insensitivity and mitochondrial dysfunction.

41 type IIb suggest the relative benzodiazepine insensitivity and more excitatory action of GABA compare

42 ffect of hepcidin, as shown by cycloheximide insensitivity, and dependent on the presence of Stat3.

43 ffect of hepcidin, as shown by cycloheximide insensitivity, and dependent on the presence of Stat3.

44 but important differences in signaling, drug insensitivity, and other key cellular processes amongst

45 The mechanisms of corticosteroid insensitivity are also determined.

46 nd the molecular mechanisms behind progestin insensitivity are poorly understood.

47 ure and the molecular basis of its rapamycin insensitivity are unknown.

48 ions in neuroblastoma appear to show de novo insensitivity, arguing that complementary therapeutic ap

49 ycemic clamp conditions, eliminating insulin insensitivity as a possible protective mechanism.

50 about the validity of structure sensitivity/insensitivity at the bottom of the catalyst size range.

51 bstruction, and the notion of corticosteroid insensitivity because potential targets for treatment ha

52 ly, lower BCR-ABL levels may indeed cause IM insensitivity, because primary murine bone marrow cells

53 obiota induced greater adiposity and insulin insensitivity compared to T1.

54 n phytochrome A and additively increases ABA insensitivity conferred by the abi2, abi4, and abi5 muta

55 alpha-Amanitin insensitivity confirmed that overexpression of miR-4443

56 g, whereas TOC1 overexpression causes thermo insensitivity, demonstrating that TOC1 mediates the even

57 This insensitivity derives from compensatory changes to the p

58 This neurosteroid insensitivity did not primarily result from perturbation

59 By contrast, mutations that confer ABA insensitivity did not promote defense responses at high

60 Cys251) to serine resulted in complete BLT-1 insensitivity, establishing that the unique molecular ta

61 ucture sensitivity, in contrast to structure insensitivity found for larger particles.

62 gnaling has been connected to cancer, and GH insensitivity has been reported in cachexia patients.

63 corticosteroid (CS) therapy, and relative CS insensitivity has been shown in airway smooth muscle cel

64 tion represents a novel mechanism driving GC insensitivity in ASM in severe asthma.

65 endotoxin might contribute to corticosteroid insensitivity in asthmatic patients.

66 endotoxin might contribute to corticosteroid insensitivity in asthmatic patients.

67 ntrations are associated with corticosteroid insensitivity in asthmatic patients.

68 egulation is thought to cause glucocorticoid insensitivity in COPD.

69 tion mutation at alpha53, may lead to HLA-DM insensitivity in HLA-DQ2.5.

70 n this work, we have analyzed glucocorticoid insensitivity in human pulmonary artery endothelial cell

71 fied pAKT and pERK phospho-heterogeneity and insensitivity in individual leukemia cells treated with

72 the AUC has recently been criticized for its insensitivity in model comparisons in which the baseline

73 The mechanisms driving glucocorticoid (GC) insensitivity in patients with severe asthma are still u

74 vity may contribute to both relative steroid insensitivity in patients with severe eosinophilic asthm

75 To uncover key mechanisms of docetaxel insensitivity in prostate cancer, we have established do

76 al cortex activity to win may reflect reward insensitivity in youth with disruptive behavior disorder

77 Whilst cytokines can induce corticosteroid insensitivity in-vitro, how current and former smoking a

78 Structure insensitivity, inherent for specific cluster sizes, is i

79 We show here that this insensitivity involves the loss of MEC-8-dependent splic

80 Our combined results indicate that U2AF insensitivity is a common phenomenon and that varied int

81 rather than a single molecule, odor-specific insensitivity is averaged out, and the test accurately d

82 This TNKSi insensitivity is conferred by beta-catenin's association

83 isceral adipose deposition, DNL, and insulin insensitivity is limited or inconclusive.

84 of languages demonstrates that letter-order insensitivity is neither a general property of the cogni

85 The latter properties and V7's oxygen insensitivity make V7 a very promising candidate to repl

86 These findings suggest that reward insensitivity may be a contributory mechanism to apathy

87 nnel subunits tested, suggesting target site insensitivity may not be important in our hop T. urticae

88 We hypothesized that this insensitivity may result from insufficient generation of

89 d in C. elegans in genetic screens for touch insensitivity (MEC-2(P134S)).

90 tions indicate that the remarkable structure insensitivity observed for CO oxidation reactions reflec

91 Increased body mass and insulin insensitivity occurred in response to HFD feeding irresp

92 remains unknown how metformin resistance or insensitivity occurs.

93 likely related to proteomic heterogeneity or insensitivity of cancer cells to DNA-repair inhibition.

94 Insensitivity of CCNE1-amplified tumors to platinum cros

95 been a longstanding challenge because of the insensitivity of conventional detection methods.

96 tral effects of inflammation are hindered by insensitivity of conventional structural magnetic resona

97 atin filament association and fosters Ca(2+) insensitivity of desmosomes in keratinocytes, presumably

98 The insensitivity of face-N200 to task manipulations has sup

99 may give rise to their damage tolerance and insensitivity of failure to the presence of flaws even w

100 6 showed a modified immune response, and the insensitivity of g6pd6 mutant plants to PAMP-induced gro

101 rved in all CAT isoforms did not lead to NEM insensitivity of hCAT-2A.

102 Due to the insensitivity of human eyes to the polarization and phas

103 degrees C, 94% rr to 50 degrees C, 93% rr); insensitivity of its high activity, degree of control, a

104 The apparent insensitivity of lambda N to crowding may also be due in

105 Given the relative insensitivity of line width to PEG size, we anticipate t

106 This insensitivity of local barrier crossing to solvent frict

107 hyl methanethiosulfonate, and the bumetanide insensitivity of M382W is consistent with tryptophan blo

108 tic center promises to overcome the inherent insensitivity of magnetic resonance.

109 Thus, although the insensitivity of models needs further investigation, bla

110 to find coding of modality is not driven by insensitivity of multivariate pattern analysis in these

111 The CAi insensitivity of NHE flux suggests that, in the native c

112 e differences that might underlie the proton insensitivity of nmrASIC3.

113 the 18:1-synthesizing gene SUPPRESSOR OF SA INSENSITIVITY OF npr1-5 (SSI2) or exogenous application

114 ution is the theoretical assumption that the insensitivity of readers to letter order reflects the sp

115 The main limitations of this study are the insensitivity of reservoir measurements, and the fact th

116 uld be due to a considerable placebo effect; insensitivity of scales to quantify stiffness, especiall

117 cotine status in HCS but not SCZ, suggesting insensitivity of SCZ to nicotine-derived performance ben

118 e 2 mechanisms cannot be clarified given the insensitivity of serum zinc to identify subclinical defi

119 aB-dependent gene promoters, may underlie CS insensitivity of severe asthma.

120 advantages over traditional SPR in terms of insensitivity of signal responses to pH and salinity, le

121 om European languages, regarding an apparent insensitivity of skilled readers to letter order.

122 The insensitivity of spine formation and elimination to sens

123 tion between the radicals, rationalizing the insensitivity of the bonding interaction to substituents

124 likely mechanisms causal for the underlying insensitivity of the CSCs to conventional therapy.

125 An intriguing insensitivity of the droplet shape toward surface hetero

126 The relative insensitivity of the method to the instrumental complian

127 omplexity of these molecules, as well as the insensitivity of the method.

128 er decoupling is further demonstrated by the insensitivity of the optical absorption and Raman spectr

129 They have also revealed an insensitivity of the peptide partition coefficient, K(p)

130 of Pt(111), in line with the known structure insensitivity of the reaction.

131 This result is in contrast to the insensitivity of the transition temperature to magnetic

132 However, intrinsic resistance (i.e., insensitivity of the tumors to therapy) remains a daunti

133 In all instances we demonstrate insensitivity of the whole-genome 3D reconstruction obta

134 However, the relative insensitivity of this genotype to most protease inhibito

135 olding of a helix-containing protein, is the insensitivity of torsion angle isomerization to solvent

136 ifurcated pore entryway and accounts for the insensitivity of two-pore domain K(+) channels to inhibi

137 The relative temperature insensitivity of VEGF secretion and its Sar1 and Arf1 in

138 (PDF) studies have been used to overcome the insensitivity of X-ray diffraction data to different tra

139 The sensitivity, or insensitivity, of catalysed reactions to catalyst struct

140 , fatty liver, hyperinsulinemia, and insulin insensitivity on chow diet without change in food intake

141 s to increased demand for control, including insensitivities or lags in fully activating the cognitiv

142 with these disorders exhibit glucocorticoid insensitivity or resistance.

143 -0.19 EU/mL], P = .042) unrelated to steroid insensitivity or serum cytokine concentrations.

144 The ABA insensitivity phenotype of hsr3 was rescued by cytochala

145 In parallel, we showed that stomatal CO2-insensitivity phenotypes of a mutant cis (CO2-insensitiv

146 itivity, more open stomata, and stomatal CO2-insensitivity phenotypes of the Arabidopsis thaliana acc

147 ironments require varieties with photoperiod insensitivity (PI) that can flower in short days.

148 gus pathogenesis, which, by reversing Ca(2+) insensitivity, promotes Dsg3 depletion.

149 3,4,5)P(3) have major limitations, including insensitivity, reliance on radiolabeling, low throughput

150 Target site insensitivity resulting from point mutations within the

151 Naturally occurring pheromone insensitivity results in part from previously described

152 cluding from patients with complete androgen insensitivity syndrome (CAIS).

153 ll AR missense mutations that cause androgen insensitivity syndrome are located in the highly structu

154 ibes the clinical manifestations of androgen insensitivity syndrome from infancy to adulthood, review

155 Androgen insensitivity syndrome in its complete form is a disorde

156 ns associated with oligospermia and androgen insensitivity syndrome map to Pro-390, the conserved pro

157 Management of androgen insensitivity syndrome should be undertaken by a multidi

158 isrupting AR function in males with androgen insensitivity syndrome.

159 highlighting a molecular switch for chloride insensitivity that is transduced through an arginine fli

160 of neutrophilic airway inflammation, steroid insensitivity, the epithelial cell profile, and airway r

161 iological adaptations (including target site insensitivity), there is strong evidence that these spec

162 Thus, we hypothesized that FGF21 causes GH insensitivity through regulation of LEPROT and/or LEPROT

163 f hippocampal CA1 neurons and anhedonic-like insensitivity to a sucrose solution also persisted despi

164 and drought stress in addition to conferring insensitivity to ABA.

165 tebrate to show physiological and behavioral insensitivity to acid pain in the skin.

166 he reaction features a high substrate scope, insensitivity to air, and excellent product yielding.

167 as the reference electrode, because of their insensitivity to air, when compared to lithium.

168 Insensitivity to antagonist addition in a real-time, lab

169 has been proposed to contribute to acquired insensitivity to anti-epileptic drugs exhibited by Nav c

170 nd has been implicated in the development of insensitivity to anti-estrogen therapy.

171 ndrial membrane potential (Deltapsi(m)), and insensitivity to bax-gene deletion, (2) underwent excito

172 rangement, speed of measurement and relative insensitivity to beam movements.

173 by applying magnetic fields, and pronounced insensitivity to both particle chemistry and harsh proce

174 ss (varphif =14.4 % at 150 mM of K(+) ), and insensitivity to both pH in the range 5.5-9.0 and other

175 Target site insensitivity to cardenolides is a prime candidate for s

176 Despite its insensitivity to changes in functional residual capacity

177 In addition, its relative insensitivity to cholesterol depletion suggests that the

178 , a lengthened and delayed circadian rhythm, insensitivity to clock-resetting morning light, and heig

179 d might be inherently inefficient due to its insensitivity to context-dependent effects.

180 ortex,which in turn predicted the behavioral insensitivity to contingency change.

181 basally elevated NMDAR function coupled with insensitivity to CORT modulation indicative of a chronic

182 Insensitivity to cycloheximide indicated that IL-33 was

183 Disruption of the CRFs results in partially insensitivity to cytokinin in a root elongation assay an

184 This study suggests that behavioral insensitivity to DEET in A. aegypti is a genetically det

185 ute restraint stress or extinction training, insensitivity to dexamethasone challenge, and reduced hi

186 A potential reason for gamma-conglutin insensitivity to digestion may be related to the fact th

187 e verified as true NP binding sites based on insensitivity to DNA antisense oligonucleotide-mediated

188 ng at double notches, despite their apparent insensitivity to DW chirality.

189 ideology, in engendering Americans' relative insensitivity to economic inequality.

190 Cells with acquired insensitivity to either folate or cAMP remain fully resp

191 function may therefore result in epithelial insensitivity to electric fields and contribute to KS di

192 Insensitivity to endocytosis inhibitors and classical st

193 subpopulation of C4-2B cells that developed insensitivity to ENZA after sustained exposure in cultur

194 ECTA-LIKE1 (ERL1) signaling confers specific insensitivity to EPF2 and EPF1, respectively.

195 on and demonstrate the predicted first-order insensitivity to errors.

196 fferent between these conditions, indicating insensitivity to escalating effort or delay costs.

197 lopment and defects in BIG or ARF1 result in insensitivity to ethylene.

198 THIK1, including inhibition by halothane and insensitivity to extracellular pH variations.

199 ice show altered beta1-integrin activity and insensitivity to Fgf2.

200 Evolved HPPD enzymes showed insensitivity to five inhibitor herbicides.

201 layed progression from G(2) into mitosis and insensitivity to G(2) arrest induced by the topoII catal

202 f activation, a reduced current density, and insensitivity to gating modulation by Ca(2+)-CaM.

203 binding sites in the amygdala and behavioral insensitivity to ghrelin receptor agonism.

204 Consistent with their documented insensitivity to glucokinase inhibitors, the glucose res

205 Basal increases in cytosolic Ca(2+) and insensitivity to H2O2-mediated Ca(2+) entry in DeltakatG

206 citability and weakness in low-K+ challenge, insensitivity to high-K+ challenge, dominant inheritance

207 s exhibit an inherent and severe ventilatory insensitivity to hypercapnia but also exhibit relatively

208 e tested the hypothesis that the ventilatory insensitivity to hypercapnia in BN rats is due to altere

209 Although they are associated with insensitivity to ibrutinib, lesions in the alternative N

210 ow BCR-ABL expression that may explain their insensitivity to IM and their low propensity to develop

211 s, in which oncogenic activity relies on p38 insensitivity to induce intracellular ROS.

212 d with inhaled steroids, suggesting relative insensitivity to inhibition by corticosteroids.

213 y to produce insulin (type 1 diabetes) or as insensitivity to insulin secreted by the body (type 2 di

214 immaturity was due to spatial limitations or insensitivity to interocular correlation, highly suprath

215 1%) of 41 studied noxy mutants have an added insensitivity to isoxaben, an herbicide inhibiting cellu

216 k of response to interferon gamma, including insensitivity to its antiproliferative effects on cancer

217 bit unrealistic oscillatory behavior and SOC insensitivity to long-term changes in C inputs.

218 limits of traditional strategies and exhibit insensitivity to lossy tissue environments.

219 Insensitivity to low SMN emerged abruptly at postnatal d

220 r1 knockout mice consume more MA and exhibit insensitivity to MA-induced CTA and hypothermia, compare

221 lective fluctuations, and the simplicity and insensitivity to material details of the 'normal' state

222 longatus in terms of spin state energies and insensitivity to methanol addition.

223 deficits were not caused by perseveration or insensitivity to negative feedback though.

224 These findings indicate that insensitivity to negative information may be a key compo

225 ical power to model rare taxa and/or species insensitivity to neighbours.

226 to excessive production of ADCY1 protein and insensitivity to neuronal stimulation.

227 Insensitivity to NLP cytolysins of monocot plants may be

228 utosomal recessive disorder characterized by insensitivity to noxious stimuli and variable intellectu

229 onsiveness to IL-28 signaling, which confers insensitivity to oncolytic virotherapy through a mechani

230 l learning and correlated with the degree of insensitivity to outcome devaluation in subsequent perfo

231 Congenital insensitivity to pain (CIP) or congenital analgesia is a

232 ns in SCN9A are known to underlie congenital insensitivity to pain (CIP).

233 from studies of individuals with congenital insensitivity to pain (CIP).

234 n SCN9A have been reported in (1) congenital insensitivity to pain (CIP); (2) primary erythromelalgia

235 gated sodium channel Nav1.7 cause congenital insensitivity to pain in humans and mice.

236 w that JNJ63955918 induces a pharmacological insensitivity to pain that closely recapitulates key fea

237 Congenital insensitivity to pain with anhidrosis (CIPA) is a rare a

238 Congenital insensitivity to pain with anhidrosis (CIPA) is caused b

239 cessive disorder characterized by congenital insensitivity to pain, inability to feel touch, and cogn

240 ead to small-fibre neuropathy and congenital insensitivity to pain, respectively.

241 , which encodes Nav1.7, result in congenital insensitivity to pain, whereas gain-of-function mutation

242 .9 mutation (L1302F) that is associated with insensitivity to pain.

243 e depolarizations cause hypoexcitability and insensitivity to pain.

244 underlies a human disorder characterized by insensitivity to pain.

245 of function mutations results in congenital insensitivity to pain.

246 n, survival or proliferation, yet timing and insensitivity to park mutation suggest that preferential

247 h dynamic range, good signal-to-noise ratio, insensitivity to pH and Mg(2+), tunable Ca(2+) affinity,

248 cross sections (150 GM) at nearly 720 nm and insensitivity to pH within the biologically relevant pH

249 horetic mobility (EPM) of GONPs indicated an insensitivity to pH, although IS did play a role.

250 ated with decreased NR2B expression and EPSP insensitivity to pharmacological blockade of NR2B, and a

251 ive to reproductive growth, as well as their insensitivity to photoperiod, establish a dual role for

252 er ions (e.g., Mg(2+), Ca(2+), K(+)) and its insensitivity to potential changes in pH, this sensor is

253 re promising therapeutic agents due to their insensitivity to protease degradation.

254 our results from excessive focus on rewards, insensitivity to punishment, or to dysfunction in a part

255 ith indolent behavior, local recurrence, and insensitivity to radiotherapy and chemotherapy.

256 g of RALF to FERONIA and reduced binding and insensitivity to RALF-induced growth inhibition in feron

257 lysis, slowed-down forward translocation and insensitivity to regulatory pauses.

258 on partially ameliorating dependence-related insensitivity to reinforcing outcomes/'liking', but havi

259 Here we investigated if insensitivity to reward might be a contributory factor a

260 However, the molecular basis of SCN CC insensitivity to RF and its possible pathological conseq

261 Rather than revealing insensitivity to rising inequality, the results suggest

262 ants with NRB4 null alleles express profound insensitivity to SA, even more than npr1.

263 P6, and ZFP7 zinc finger factors confers ABA insensitivity to seed germination, while the zfp3 zfp4 d

264 l tracking involves repeated refractoriness (insensitivity to sensory information for a certain durat

265 incurs substantial, serial, refractoriness (insensitivity to sensory information of 350 and 550 ms f

266 bility to identify poor performers, relative insensitivity to severity adjustment, and the ability to

267 cs featuring large Stokes shifts and general insensitivity to solvent or pH.

268 ia has been thought to arise from alpha-cell insensitivity to suppressive effects of glucose and insu

269 failed for nearly half of the species due to insensitivity to temperature change at To .

270 ct electronic measurements, we show from its insensitivity to temperature, magnetic field and doping,

271 , the current study is the first to link Fas insensitivity to the actions of a specific sialyltransfe

272 teins recycle constitutively and demonstrate insensitivity to the endocytic effects of AMPH and PKC (

273 ion by the glycine-site antagonist CNQX, and insensitivity to the glutamate-site antagonist d-APV.

274 autism spectrum disorders (ASDs) often show insensitivity to the human voice, a deficit that is thou

275 zation, extremely long depolarization times, insensitivity to the in vivo environment or particle tum

276 nt spatial velocity, constant amplitude, and insensitivity to the initial stimulation once it exceede

277 with systemic lupus erythematosus displayed insensitivity to the regulation of IL-12.

278 looking in autism is consistent with passive insensitivity to the social signals in others' eyes.

279 t advantage of the proposed technique is its insensitivity to the thermal interfacial impedance and i

280 This new technique has great advantages of insensitivity to thermal effects, the bias current, and

281 However, insensitivity to these chemotherapeutic agents including

282 om compensatory mechanisms and which reflect insensitivity to those particular parameters.

283 The lack of moving parts and insensitivity to vibration allow for lower noise and imp

284 vity of GABA-evoked currents to diazepam and insensitivity to Zn(2+), together with the weak direct a

285 mind (modularity, reflexiveness, and context-insensitivity) to argue cognition does not fundamentally

286 Thanks to the penetrating properties and the insensitivity toward the electric conduction properties

287 hage (phiCr30), and the loss of HvyA confers insensitivity towards phiCr30.

288 Crossing experiments showed the "insensitivity" trait to be dominant.

289 with second-line treatments targeting innate insensitivity, up to 100% of mice that would have otherw

290 This action drives GC insensitivity via protein phosphatase 5-dependent impair

291 mata opening, enhanced leaf cooling, and ABA insensitivity was conserved with OsRZFP34 expression.

292 We investigated whether corticosteroid insensitivity was present in airway smooth muscle cells

293 Glucocorticosteroid insensitivity was selective for proinflammatory cytokine

294 inked to either cold-aggravated pain or pain insensitivity, we propose a model in which the physiolog

295 r tests to identify patterns of response and insensitivity were performed when tissue was available.

296 e the development of age-dependent quercetin insensitivity when continued supplementation fails to dr

297 eins, but not others, confer constitutive JA-insensitivity when overexpressed in plants.

298 sociated with significant lymphocyte steroid insensitivity, which improves in recovery and can be ame

299 , a consequence of del(8p), results in TRAIL insensitivity, which may contribute to ibrutinib resista

300 sociated with increased appetite and insulin insensitivity, while chronically sleep-deprived individu