ライフサイエンスコーパス: instill

1 1 mg/0.1 bolus of intracameral cefazolin was instilled).

2 or without alpha1-AT or alpha1-AT alone was instilled.

3 w 80 mm Hg, when 100 mg/kg of surfactant was instilled.

4 luorocarbon-associated gas exchange (n=9) by instilling 1.6 L of unoxygenated perflubron into the tra

5 lacement-sensitive system, the percentage of instilled (125)I-labelled albumin counts remaining in lu

6 Approximately 25 % of instilled (125)I-labelled albumin was cleared from the l

7 A drop of the lipid emulsion was then instilled; 15 minutes later, two interferometry measurem

8 or 4 times daily (n=74); pazopanib 10 mg/ml instilled 2 (n=73), 3 (n=73), or 4 times daily (n=72); o

9 58.9 +/- 8.3 kg, had lung injury induced by instilling 2 mL/kg of 0.05 Normal hydrochloric acid into

10 lled 4 times daily (n=73); pazopanib 5 mg/ml instilled 3 (n=72) or 4 times daily (n=74); pazopanib 10

11 Nepafenac (0.1%) eye drops were instilled 3 times a day in the eye that received treatme

12 nd sustained antifibrotic activity, we first instilled 3H- and 14C-labeled cHyp polymer in normal rat

13 ered for 52 weeks included placebo eye drops instilled 4 times daily (n=73); pazopanib 5 mg/ml instil

14 0 mug, or placebo) was followed by eye drops instilled 4 times per day for 21 days with placebo, plac

15 s, each patient's tears were collected after instilling 50 mul of sterile saline to the lower cul-de-

16 Absorption of intranasally instilled 54Mn was significantly reduced in Belgrade rat

17 beta-stimulated Smad 3 acts as a key node to instill a feedback loop between deptor down-regulation a

18 ge introduction, under endoscopy was used to instill a millimolar aqueous solution of Tb-PCTMB into a

19 t perspectives and ways of thinking that can instill a new dimension to delivering healthcare service

20 s of vaccine-induced CD8(+) T cell responses instill a predictive determinant for the efficacy of vac

21 ions to promote certain health behaviors may instill a virtuous cycle with benefits that accumulate a

22 We instilled a solution of 5% albumin in 0.9% NaCl with 3 m

23 After instilling a 5-mul fluorescein drop into the inferior fo

24 ing the intravesical ureter and subsequently instilling a broth culture of E. coli into the bladder.

25 When IL-18 was instilled, a significant increase in peribronchial eosin

26 Two milliliter of methylene blue were instilled above the cuff to quantify microaspirations, a

27 rship (particularly at attending level), and instilling accountability.

28 ween eyes and an investigative lubricant was instilled after 4 hours of lens wear.

29 advancing a closed-system suction catheter, instilling aliquot portions of saline, and suctioning th

30 ethical dilemmas and concerns for the donor instilled ambivalence about living donation.

31 st (CAPT) reproduces the events occurring by instilling an allergen on the ocular surface.

32 hetized, ventilated rats over one hour after instilling an isosmolar 5% albumin solution in Ringer's

33 Program aimed to instill and develop healthy behaviors in relation to die

34 lm and cornea, 2 microliters of 0.35% F were instilled and 10 fluorescence scans were obtained at app

35 Controls were house dust mite-instilled animals receiving intravenous vehicle or phosp

36 avenous vehicle or phosphate-buffered saline-instilled animals receiving mesenchymal stem cells.

37 In each group, we instilled approximately 10(8) colony-forming units of E.

38 When KC was instilled as a proinflammatory stimulus, neutrophil accu

39 ied out by the quality control machinery was instilled at the tetramerization step.

40 ALC was determined by instilling autologous plasma into a lower lung lobe and

41 nd pyogranulomatous pneumonia centred on the instilled beads.

42 Routine topical mydriatics were instilled before surgery.

43 sodium hyaluronate (SH)-based comfort drop, instilled before the insertion of contact lenses, in a p

44 n bleomycin-induced fibrosing alveolitis, we instilled bleomycin intratracheally into gelatinase B-de

45 Endotoxin (4 ng/kg) was then instilled bronchoscopically in the right middle lobe.

46 his mouse model, a more-human BS pool can be instilled by BS feeding, without hepatic damage, which m

47 d by lavage, consisting of a 35 ml/kg volume instilled by gravity and followed immediately by passive

48 Our results should instill caution in those considering similarly designed

49 Furthermore, a locally instilled ceramide analog significantly increased virus-

50 d with successful transition into the clinic instill confidence that mda-7/IL-24, as a single or more

51 of the individual conformational states, and instills conformational discipline by greatly narrowing

52 c subjects and in their response to directly instilled cool, dry air.

53 erimental settings, ultrafine air pollutants instilled directly into the cardiac vasculature depress

54 Purified PVL instilled directly into the lung caused lung inflammatio

55 Porphine (500 microM) + 1% albumin is instilled directly into the tears of a sedated rabbit, a

56 ), instilled surfactant followed by a second instilled dose (Inst/Inst), instilled surfactant followe

57 ations implied absorption of 0.5% to 5.5% of instilled dose.

58 ; 95% CI, 2.2-9.7; P </= 0.0001), difficulty instilling drops (OR, 2.3; 95% CI, 1.1-4.9; P = 0.03), f

59 In LPS-instilled F344/N rats, the percentage of Bcl-2-positive

60 by killing them, competing for resources and instilling fear, but it is unclear how suppression of me

61 ng), IL-1beta (1 ng), or IL-6 (100 pg) were instilled for 1 hour, either individually or together.

62 zation mouse model, Amb-APE was intranasally instilled for 11 consecutive days.

63 odistribution and toxicity of intravesically instilled free QD and anti-CD47-QD in mice.

64 cal medicine, in general, and will hopefully instill greater confidence in the clinical community reg

65 The effect of mucosally instilled GSH and other reductive and nonreductive agent

66 We instilled HCl through the airway, and we quantified lung

67 ears offer a unique window of opportunity to instill healthy life-style behaviors and promote cardiov

68 Program is an effective strategy for instilling healthy habits among preschoolers, translatin

69 cacy trials of HIV and malaria vaccines have instilled hope that another golden age of vaccines may b

70 Intranasally instilled HRP was similarly prevented from permeating th

71 Experiments with intranasally instilled HRP were also carried out.

72 Ten lung-damaged pigs (instilled hydrochloride).

73 mproving P-V mechanics almost to normal when instilled in lavaged, excised rat lungs at 37 degrees C

74 osphaturia is not elicited when phosphate is instilled in other parts of the gastrointestinal tract s

75 normal saline in increments of 3-50 mL were instilled in the bladder via a urethral catheter.

76 When instilled in the bladder, there is little leakage of IUd

77 f live (5 x 10(11) colony-forming units) was instilled in the both lung lobes through a bronchoscope.

78 One hundred ng of tritiated NNK were instilled in the distal trachea of the dog.

79 n (dpi) rose bengal or lissamine green B was instilled in the left eyes.

80 Before insertion of the lenses, SH drops was instilled in the lens for half of the group.

81 BALB/c mouse model and demonstrate that when instilled in the live murine eye, RSV not only replicate

82 Radiolabeled TNF-alpha instilled in the lung significantly leaked into the circ

83 Chlorohydrins were also instilled in the rats' peritoneal cavity, and their effe

84 linical isolate of mucoid P. aeruginosa were instilled in the right lung of normal or CF mice.

85 hepatocytes and Chinese hamster ovary cells instilled in these cells the ability to convert 18:2(n-6

86 use allergen-induced as well as direct MCP-1 instilled-induced changes in airway hyperreactivity were

87 kg) instilled into a lung segment and saline instilled into a contralateral segment followed by bronc

88 hen administered by intravenous injection or instilled into a different region of the lung, PLL or PL

89 Endotoxin was instilled into a dorsal hand vein for 1 hour and then re

90 f which were supplemented with PC) were then instilled into a loop of distal ileum of anesthetized ra

91 ation, 34 subjects had endotoxin (1-4 ng/kg) instilled into a lung segment and saline instilled into

92 ents, recombinant adenoviruses were directly instilled into angioplasty-injured porcine carotid arter

93 do so, Escherichia coli was intratracheally instilled into C57BL/6 mice in the presence of neutraliz

94 macrophages in vivo when it is intranasally instilled into dexamethasone-immunosuppressed, Pneumocys

95 (125)I-labelled albumin was instilled into distal airspaces of lungs, and the result

96 , PC, or Indo, alone and in combination, was instilled into ileal loops.

97 e neutrophil migration toward CXC chemokines instilled into lungs of mice.

98 a-producing macrophages were intratracheally instilled into mechanically ventilated scid mice.

99 the receptor-mediated agonist, thrombin, was instilled into microvessels in a restricted region of is

100 polymers cause an influx of neutrophils when instilled into murine lungs.

101 When instilled into normal lung, SLPI also caused similar cha

102 Elastase was instilled into rat lungs, producing changes characterist

103 hange in concentration of a protein solution instilled into the airspaces 5 h after the onset of haem

104 saline containing radiolabelled albumin was instilled into the airspaces.

105 Recombinant IL-18 (200 ng) was instilled into the airway at the time of allergen challe

106 Moreover, when instilled into the airways of antigen-sensitized recipie

107 Ovalbumin (OVA) was instilled into the airways of mice together with a wide

108 functional cells, however, and when directly instilled into the airways of mice, bypassing their need

109 atory protein-1alpha, eotaxin, or MCP-3 were instilled into the airways of normal mice or when mast c

110 In adults, a standard volume (25 mL) is instilled into the bladder to measure IAP.

111 2-microm polystyrene latex beads were either instilled into the conjunctival sac for 20 to 120 minute

112 Fluorescein-labeled bacteria were instilled into the conjunctival sac for up to 130 minute

113 rial species, present in the human duodenum, instilled into the ductal system of the pancreas in heal

114 5 mL/kg of 20% meconium in normal saline was instilled into the endotracheal tube.

115 or rhodamine-labeled latex microspheres, was instilled into the guinea pig trachea.

116 Hydrochloric acid was instilled into the left mainstem bronchus of TLR4-defect

117 e treated with tacrolimus 0.03% eye ointment instilled into the lower fornix twice daily for the firs

118 wing LPS infusion, surfactant (50 mg/kg) was instilled into the lung and the animals were placed on 7

119 Two hours after LPS infusion, saline was instilled into the lung as a control for surfactant inst

120 s applied first and surfactant or saline was instilled into the lung while maintaining positive press

121 onal to the number of transduced macrophages instilled into the lung.

122 re treated with hu5C8 at the time vector was instilled into the lung.

123 f Escherichia coli or Pseudomonas aeruginosa instilled into the lungs 24 h later.

124 ining 2-5 x 10(11) colony forming units) was instilled into the lungs according to an established pro

125 ric acid (pH = 1.5 in 1/3 normal saline) was instilled into the lungs of anesthetized, ventilated rab

126 applied to cultured lung epithelial cells or instilled into the lungs of animals.

127 These new Ad/CFTR vectors were instilled into the lungs of immunocompetent C57BL/6, BAL

128 Unexpectedly, when instilled into the lungs of mice the CXCL8 mutants recru

129 When instilled into the lungs of mice, particle composition a

130 hen enzymatically active tryptase beta I was instilled into the lungs of mice.

131 P. aeruginosa-laden agarose beads were instilled into the lungs of mice.

132 o the Survanta, then mixed with meconium and instilled into the lungs.

133 Quantum dots instilled into the mouse vagina were transported across

134 M GSH, 2 mM GSH-MEE, or 0.1 mM ebselen, when instilled into the mucosal fluid, resulted in 30%, 45%,

135 When vitamin C was instilled into the nasal epithelium of human subjects, i

136 ng randomization, Pseudomonas aeruginosa was instilled into the oropharynx.

137 encoding eNOS (AdeNOS) or beta-galactosidase instilled into the periarterial sheath at a concentratio

138 is of apoptotic polymorphonuclear leukocytes instilled into the peritoneum.

139 oligonucleotide (but not the sense control) instilled into the pulmonary vasculature at the time of

140 ith quantum dot nanoparticles, and the cells instilled into the rat bladder in vivo, after which the

141 Deoxycholic acid (DCA) was instilled into the rat colon daily for 3 days and animal

142 P. aeruginosa (109 colony forming units) was instilled into the right lungs of rabbits that were then

143 Fibrogenic or nonfibrogenic substances were instilled into the right upper lobe of rabbit lungs.

144 m enteroclysis, in which contrast agents are instilled into the small bowel via a catheter placed in

145 ltiplicity of infection of approximately 10) instilled into the SO2-injured tracheas of anesthetized

146 Microspheres were instilled into the subglottic trachea to assess pulmonar

147 ram-negative bacteria Pseudomonas aeruginosa instilled into the trachea better than did wild-type mic

148 Fast blue dye instilled into the trachea retrogradely labeled nerve ce

149 uce acute lung injury, hydrochloric acid was instilled into the tracheas of paralyzed sheep receiving

150 liquid plug of very small volume (<1 mL) is instilled into the upper airways, and with programmed ai

151 oke via tracheostomy, and P. aeruginosa were instilled into their airways.

152 nhibited by short interfering RNAs (siRNAs), instilled intranasally in the mouse, with or without tra

153 t fraction or the major allergen Amb a 1 was instilled intranasally on 1-11 consecutive days, and all

154 agnostic LP followed by a median of 4 LPs to instill intrathecal chemotherapy.

155 agnostic LP followed by a median of 4 LPs to instill intrathecal chemotherapy.

156 kg polymer containing 8.5 mg/kg cHyp or tHyp instilled intratracheally at 7 and 14 d after bleo.

157 Recombinant IL-6 instilled intratracheally at commencement of injury led

158 These labeled cells, instilled intratracheally into normal mice, migrated int

159 eumoniae (7.2 x 105 or 1.9 x 107 cfu/mL) was instilled intratracheally into untreated C57Bl/6 mice, C

160 ophils, incubated with OVA Ag in vitro, were instilled intratracheally into wild-type recipient mice

161 Next, rats were instilled intratracheally with either saline (sal) or 1.

162 n equal amount of normal saline (pH 5.3) was instilled intratracheally.

163 We instilled *IUdR for 2 hr directly within the bladder lum

164 theters inserted, lung injury was induced by instilling kerosene (0.3 mL/kg) into the trachea.

165 Here, we describe an intratracheally instilled lentiviral system able to deliver genes select

166 Systemic biodistribution of locally instilled lentiviral vector to other organs was not dete

167 d cell-mediated autoimmune diseases, and can instill long-lived allogeneic and xenogeneic graft toler

168 nchoalveolar lavage fluid recovered from the instilled lung (p = 0.005) and widened alveolar-arterial

169 y activated JNK was detected in IPF- and BLM-instilled lung tissue samples, which was dramatically su

170 C mitochondria in this protection, we airway-instilled mice first with lipopolysaccharide (LPS) and t

171 ct on cytokine induction in the lungs of CFA-instilled mice.

172 l group, we recovered 1.35% +/- 1.24% of the instilled microspheres per gram of tracheal secretions,

173 albumin (studied over a range of 0-10 g (100 instilled ml)(-1)) inhibited 40 % of the transport of la

174 elled albumin ((5.7 +/- 0.4) x 10(5) counts (instilled ml)(-1)) with an IC(50) value of 0.34 g (100 m

175 Experiments performed using a bleomycin-instilled mouse model of pulmonary fibrosis showed that

176 l (C, n = 10) and emphysematous (E, elastase instilled, n = 7) hamsters.

177 tention and translational control mechanisms instills nanos accumulation uniquely in the sMic lineage

178 ransfer immunotherapy in clinical trials has instilled new hope for the use of T-cell immunotherapy i

179 When the same number of organisms were instilled on days 0 and 7, emigration was reduced to 15

180 d European Union) were randomized 2:1 to LBN instilled once daily (QD) in the evening and vehicle in

181 When we instilled ovalbumin into the trachea of ovalbumin-sensit

182 After instilling PAF into the airways of guinea pigs and rats,

183 We report on the effects of instilling PAR-activating peptides (PAR-APs, including P

184 Partial liquid ventilation was initiated by instilling perflubron during conventional mechanical ven

185 Perflubron priming was achieved by instilling perflubron via the endotracheal tube in an am

186 ower airway inflammation, we intratracheally instilled prokaryotic and eukaryotic DNA in C3H/HeBFEJ m

187 se can be abrogated by oral tolerization, we instilled protein extracts of a recombinant adenovirus t

188 ermates, were unable to clear intrapulmonary-instilled Pseudomonas aeruginosa, despite a marked incre

189 m wild-type mice in their airway response to instilled residual oil fly ash or acute ozone exposure;

190 Cross-linking was performed by instilling riboflavin 0.1% solution containing 20% dextr

191 A sublethal dose of instilled ricin (2 microg/100 g body weight) induced a s

192 spleen, liver, and blood, demonstrating that instilled ricin gained access to the circulation.

193 lized surfactant achieved results similar to instilled surfactant but at a lower total dose.

194 ved nebulized natural surfactant (Neb Only), instilled surfactant followed by a second instilled dose

195 owed by a second instilled dose (Inst/Inst), instilled surfactant followed by nebulized surfactant (I

196 Overall, instilled surfactant had a reasonably homogeneous distri

197 distribution of ultrasonic nebulized versus instilled surfactant in the treatment of surfactant defi

198 A pressing question is whether the instilled surfactant mixture actually reaches the adult

199 lacement by facilitating the distribution of instilled surfactant to this compartment.

200 d a distribution pattern similar to that for instilled surfactant.

201 ts significantly decreased the engulfment of instilled target apoptotic thymocytes by resident AM.

202 reading frame in Chinese hamster ovary cells instilled the ability to convert 20:3(n-6) to 20:4(n-6).

203 that values the portrayal of competency and instills the value of surgical autonomy.

204 ining 2-5 x 10(11) colony-forming units were instilled through a bronchoscope into the right lower an

205 One of three extracts (500 microg) was instilled through the bronchoscope into the lungs of non

206 vening and vehicle in the morning or timolol instilled twice a day (BID) for 3 months.

207 Perfluorocarbon was then instilled via the endotracheal tube in an amount estimat

208 atrine (n = 6) was 30.4 +/- 1.6 (SE)% of the instilled volume compared with 14.1 +/- 2.1% observed in

209 Lung histology was normal in saline-instilled wild-type and COX-deficient mice.

210 ere not subjected to the carcinogen but were instilled with *IUdR.

211 art failure (SHHF) rats were intratracheally instilled with 0.0, 0.25, or 1.0 mg LA (with saline as t

212 The kidneys of mice instilled with a lethal dose of ricin showed accumulatio

213 instillation of bleomycin (control mice were instilled with a saline solution).

214 iately irrigated with nonbuffered saline and instilled with a solution of the ICG pHLIP construct, in

215 Our results show that syndecan-1-null mice instilled with allergens exhibit exaggerated airway hype

216 deficient adenovirus encoding CCL18 and then instilled with bleomycin; control mice were challenged w

217 ed and noncolonized animals were secondarily instilled with different bacterial species (Pseudomonas

218 protein leak by 55% in mice intratracheally instilled with FMLP.

219 Subsequently, graft lungs were instilled with gastric aspirate daily (3 mL/hrX8 hr/day)

220 ce of human mitochondrial DNA in mouse lungs instilled with hBMSCs.

221 ti-alphav beta6 treated wild-type mice, were instilled with live P. aeruginosa.

222 Mice instilled with OVA together with very low doses (</=10(-

223 hock and bacteremia in the animals that were instilled with PA103.

224 The nasal cavity of Fisher-344 rats was instilled with rhodamine-labeled latex microspheres.

225 After challenge, mice were intratracheally instilled with saline vehicle or 3 mg/kg (approximately

226 airway when wild-type mice are intranasally instilled with several biochemically distinct inducers o

227 5-wk-old mice, nasally instilled with tolerogenic doses of HEL p106-116, also s