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1 cts regarding leukemia inhibitory factor and insulin-like growth factor 1.
2 model assessment of insulin resistance, and insulin-like growth factor 1.
3 pinal cord, and normalization of circulating insulin-like growth factor 1.
4 emoattractant protein-1, IL-6, IL-1beta, and insulin-like growth factor-1.
5 of growth factors such as interleukin-6 and insulin-like growth factor-1.
6 ccumulation, which was confirmed in vitro as insulin-like growth factor-1, a known mediator of physio
9 ve/HER2-negative tumors (interaction between insulin-like growth factor 1 and ER: P = .002; FDR, 0.03
11 n kinase, mammalian target of rapamycin, and insulin-like growth factor 1 and their roles regulating
12 RNA expression, but it was increased by both insulin-like growth factor-1 and high, but not low, dose
13 ignificantly influence circulating levels of insulin-like growth factor-1 and insulin-like growth fac
14 ained only a modest amount of variability in insulin-like growth factor-1 and insulin-like growth fac
15 tress syndrome were strongly associated with insulin-like growth factor-1 and insulin-like growth fac
17 tary restriction, which reduces the level of insulin-like growth factor-1 and of other growth factors
19 oligomers, chronic oxidative stress, reduced insulin-like growth factor 1, and astrocytic mediated-Ab
20 reased hippocampal levels of neurotrophin 3, insulin-like growth factor 1, and nerve growth factor an
21 proteinases, and leukemia inhibitory factor, insulin-like growth factor 1, and pentraxin 3, 3 predict
22 ence of transforming growth factor beta1 and insulin-like growth factor 1, and this effect was reduce
23 e MM cell growth conferred by interleukin-6, insulin-like growth factor-1, and bone marrow stromal ce
24 absorption, stimulation of the secretion of insulin-like growth factor-1, and enhancement of lean bo
25 ocardial vascular endothelial growth factor, insulin-like growth factor-1, and hepatocyte growth fact
27 d expression of colony stimulating factor-1, insulin-like growth factor-1, and vascular endothelial g
28 , SP and its metabolites in combination with insulin-like growth factor-1 are shown to promote the co
29 deficiencies in growth hormone signaling and insulin-like growth factor-1 are strongly associated wit
30 m levels of nonfasting glucose, insulin, and insulin-like growth factor-1 as well as high levels of g
31 Perfluoroalkyl substances, sex hormones, and insulin-like growth factor-1 at 6-9 years of age: a cros
32 data suggest that an altered growth hormone/insulin-like growth factor 1 axis, which may be common t
34 ich was amplified by MCL-specific cytokines (insulin-like growth factor-1, B-cell activating factor,
35 ctivated by tonic treatment with insulin and insulin-like growth factor-1 but not by depolarization a
38 as well as four long-lived mutants (insulin/insulin-like growth factor-1, dietary restriction, prote
39 story, medications, and laboratory findings (insulin-like growth factor 1, follicle-stimulating hormo
42 entified dysregulation of the Growth Hormone/Insulin-like Growth Factor-1 (GH/IGF-1) pathway as well
45 Mouse models suggest that recombinant human insulin-like growth factor 1 (IGF-1) (rhIGF1) (mecasermi
47 L-17 mRNA levels, enhanced the expression of insulin-like growth factor 1 (IGF-1) and IL-10 and stimu
48 ere associated with plasma concentrations of insulin-like growth factor 1 (IGF-1) and insulin-like gr
49 egulate activity-dependent molecules such as insulin-like growth factor 1 (IGF-1) and interleukin-1be
52 us polymorphisms lie within HtrA1's putative insulin-like growth factor 1 (IGF-1) binding domain.
53 In breast carcinomas, increased levels of insulin-like growth factor 1 (IGF-1) can act as a mitoge
54 igitumumab, an anticancer drug that prevents insulin-like growth factor 1 (IGF-1) from binding to its
56 ciation between blood lead levels (BLLs) and insulin-like growth factor 1 (IGF-1) has not been charac
59 rowth delay is associated with low levels of insulin-like growth factor 1 (IGF-1) in a mouse model of
60 The objective is to investigate the role of insulin-like growth factor 1 (IGF-1) in the regulation o
65 mones and neuropeptides, such as insulin and insulin-like growth factor 1 (IGF-1) likely modulate gly
66 spective case-control studies suggested that insulin-like growth factor 1 (IGF-1) or insulin-like gro
68 marrow (BM)-derived interleukin-6 (IL-6) and insulin-like growth factor 1 (IGF-1) secretion, thus inh
69 ed signaling networks, including the insulin/insulin-like growth factor 1 (IGF-1) signaling cascade a
70 ly attenuated by a deficiency in the insulin/insulin-like growth factor 1 (IGF-1) signaling in C. ele
71 t or energy levels-most notably, the insulin/insulin-like growth factor 1 (IGF-1) signaling pathway,
72 nction through the regulation of the insulin/insulin-like growth factor 1 (IGF-1) signaling pathway.
75 liferation by modulating a decrease in serum insulin-like growth factor 1 (IGF-1) that allows GH rele
76 f the pro-osteoclastogenic factors RANKL and insulin-like growth factor 1 (IGF-1) to induce osteoclas
79 glial fibrillary acidic protein (GFAP), and insulin-like growth factor 1 (IGF-1) were analyzed 12 ho
80 anismal level as shown by down-regulation of insulin-like growth factor 1 (IGF-1), a hallmark of prem
82 pe 2 diabetes mellitus (T2DM) via binding of insulin-like growth factor 1 (IGF-1), an insulin-like ho
84 ile groups) of circulating concentrations of insulin-like growth factor 1 (IGF-1), insulin-like growt
85 ng serum concentrations of glucose, insulin, insulin-like growth factor 1 (IGF-1), insulin-like growt
87 schistosome-infected pregnancies, including insulin-like growth factor 1 (IGF-1), tumor growth facto
90 acetylation region of Rictor exhibit reduced insulin-like growth factor 1 (IGF-1)-stimulated mTORC2 k
95 +DE patient serum revealed altered levels of insulin-like growth factor 1 (IGF-I) and its binding pro
98 In addition to IRBP, the IPM also contains insulin-like growth factor-1 (IGF-1) and its associated
99 scular endothelial growth factor-A (VEGF-A), insulin-like growth factor-1 (IGF-1) and Klotho, in the
101 recurrent GBM, driven by macrophage-derived insulin-like growth factor-1 (IGF-1) and tumor cell IGF-
102 e investigated the effects of overexpressing insulin-like growth factor-1 (IGF-1) as a potential ther
103 expression and phosphorylation, counteracted insulin-like growth factor-1 (IGF-1) binding to CLL cell
104 ts stimulatory effects primarily mediated by insulin-like growth factor-1 (IGF-1) both systemically a
105 ed that increased expression of IL-1beta and insulin-like growth factor-1 (IGF-1) coincided with indu
106 e previously shown that systemic infusion of insulin-like growth factor-1 (IGF-1) exerts anti-inflamm
109 us, we expected autophagy to be activated by insulin-like growth factor-1 (IGF-1) inhibition, which c
113 -beta3) with varying release kinetics and/or insulin-like growth factor-1 (IGF-1) on osteochondral ti
114 eurons, have triggered a renewed interest in insulin-like growth factor-1 (IGF-1) pathway activation
116 e MC4R, we assessed pulsatile GH release and insulin-like growth factor-1 (IGF-1) production and/or r
118 of adult rabbit extraocular muscle (EOM) to insulin-like growth factor-1 (IGF-1) results in signific
122 atory pathway for E2F-2 production involving insulin-like growth factor-1 (IGF-1) signaling is simult
123 -kinase (PI3K) that functions in the insulin/insulin-like growth factor-1 (IGF-1) signaling pathway.
124 mediates adipogenesis and show a link to the insulin-like growth factor-1 (IGF-1) signaling pathway.
125 ells secrete a subthreshold concentration of insulin-like growth factor-1 (IGF-1) that primes the IGF
129 poor phagocytosis, reduced up-regulation of insulin-like growth factor-1 (IGF-1), and impaired muscl
130 ysiological declines in growth hormone (GH), insulin-like growth factor-1 (IGF-1), and sex steroids.
131 ascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1), haemodynamic chang
133 ce (95% CI) was computed for levels of serum insulin-like growth factor-1 (IGF-1), leptin, and adipon
134 ated with endothelin (ET-1), norepinephrine, insulin-like growth factor-1 (IGF-1), or isoproterenol a
135 elaborates the cardioprotective polypeptide, insulin-like growth factor-1 (IGF-1), which activates IG
136 motility was regulated by norepinephrine and insulin-like growth factor-1 (IGF-1), which increased or
139 resistance leading to low concentrations of insulin-like growth factor-1 (IGF-1); relative hypercort
140 n epidermal growth factor receptor (HER) and insulin-like growth factor-1 (IGF-1R) family of receptor
141 growth hormone concentration >2.5 mug/L and insulin-like growth factor 1 [IGF-1] concentration >1.3
143 is characterized by a marked decrease in the insulin-like growth factor 1 (IGF1) and IGF1 receptor (I
144 o-expression of two soluble proteins, namely insulin-like growth factor 1 (IGF1) and osteopontin (OPN
147 ingly, treatment of RTT-derived neurons with Insulin-like Growth Factor 1 (IGF1) could rescue some of
148 ain-derived neurotrophic factor that affects insulin-like growth factor 1 (IGF1) expression in Mecp2(
150 novel MALDImmunoassay for quantification of insulin-like growth factor 1 (IGF1) in human plasma.
151 at phorbol ester 12-myristate 13-acetate and insulin-like growth factor 1 (IGF1) induced rod differen
153 osensor for the determination of the hormone insulin-like growth factor 1 (IGF1) is reported for the
155 receptor tyrosine kinases by neuregulin and insulin-like growth factor 1 (IGF1) leads to the phospho
156 ed that mouse strains with lower circulating insulin-like growth factor 1 (IGF1) level at 6 mo have s
158 EVIEW: To summarize the recent evidence that insulin-like growth factor 1 (IGF1) mediates growth effe
163 es indicate that insulin receptors (IRs) and insulin-like growth factor 1 (IGF1) receptors (IGF1Rs) c
164 ression caused reduced fat stores, pituitary insulin-like growth factor 1 (IGF1) resistance, and a de
166 ffects of (56)Fe radiation on adipokines and insulin-like growth factor 1 (IGF1) signaling axis in mo
167 toxic inflammation, increases cytoprotective insulin-like growth factor 1 (IGF1) signaling, and preve
170 ing to a pronounced reduction in circulating insulin-like growth factor 1 (IGF1), and ASO-10-27 treat
171 ytosis-related genes, including Mmp9, Mmp12, insulin-like growth factor 1 (Igf1), and Glycoprotein (t
172 Human fibroblast growth factor 2 (FGF2) and insulin-like growth factor 1 (IGF1), are canonical proto
173 reased cellular sensitivity to estradiol and insulin-like growth factor 1 (IGF1), as measured in grow
174 or muscle growth, including the induction of insulin-like growth factor 1 (IGF1), as well as concomit
175 d preadipocytes to differentiation inducers [insulin-like growth factor 1 (IGF1), glucocorticoid, and
176 ulin growth factor (IGF) signaling including insulin-like growth factor 1 (IGF1), IGF1 receptor (IGF1
177 ted sites cluster on the binding surfaces of insulin-like growth factor 1 (IGF1), IGF1 receptor (IGF1
181 n, or co-overexpression of osteopontin (OPN)/insulin-like growth factor 1 (IGF1)/ciliary neurotrophic
182 oxo1, a key downstream signaling molecule of insulin-like growth factor 1 (IGF1)/insulin actions, reg
186 ical stimulation that significantly promoted insulin-like growth factor-1 (IGF1) production and elici
187 ion and proliferation as well as insulin and insulin-like growth factor-1 (IGF1) receptor activation
189 eration, the expression of cellular insulin, insulin-like growth factor-1 (IGF1), and GHRH receptor,
193 , and Fox transcriptional targets (p21, p27, insulin-like growth factor 1 [IGF1]) also were examined.
194 cer pinpoint to a potential new function for insulin-like growth factor 1 (Igf1r) in the basal epithe
198 factors transforming growth factor beta1 and insulin-like growth factor 1 in the chronically inflamed
199 es activated by growth hormone, insulin, and insulin-like growth factor-1 in mammals and their orthol
200 zation of the conserved longevity regulator, insulin-like growth factor-1, in the marrow microenviron
201 nel of serologic testing that included serum insulin-like growth factor-1, insulin-like growth factor
202 growth factor-1 systemically pointed to the insulin-like growth factor-1-insulin-like growth factor-
204 changes including altered levels of insulin, insulin-like growth factor-1, leptin, adiponectin, stero
205 eased expression of pro-regenerative factors insulin-like growth factor 1, leukemia inhibitory factor
206 ands, and feet and are diagnosed by elevated insulin-like growth factor 1 levels and growth hormone l
208 Evaluation III was strongly associated with insulin-like growth factor-1 levels; and age was strongl
209 ntial circulating modulators of muscle mass--insulin-like growth factor-1, myostatin, and growth and
211 gus serum as well as novel therapies such as insulin-like growth factor 1, neuropeptides and acupunct
212 and fibrin extracellular matrix proteins and insulin-like growth factor 1 on the force production of
213 TRPC6 complementation and by treatment with insulin-like growth factor-1 or hyperforin, a TRPC6-spec
214 -1 and AKT following stimulation by insulin, insulin-like growth factor-1, or the neurotrophins (NGF
215 n Index scores correlated significantly with insulin-like growth factor-1 (P < 0.03) and insulin-like
219 ation but instead sustained signaling of the insulin-like growth factor 1/phosphatidylinositol 3-kina
220 a3(L122P) mice displayed an 80% reduction in insulin-like growth factor 1, postnatal growth retardati
221 nclude mammalian target of rapamycin, c-MET, insulin like growth factor 1 receptor and cytotoxic T-ly
223 the insulin receptor (F-IRKO) or both IR and insulin-like growth factor 1 receptor (F-IR/IGFRKO).
224 atric skin display reduced activation of the insulin-like growth factor 1 receptor (IGF-1R) and alter
225 he closely related receptor tyrosine kinases insulin-like growth factor 1 receptor (IGF-1R) and insul
226 iates for the activation of PI3K by both the insulin-like growth factor 1 receptor (IGF-1R) and its c
229 rs revealed 6ha as preferential inhibitor of insulin-like growth factor 1 receptor (IGF-1R) in a pane
232 tor 2 (IGF2) gene, encoding a ligand for the insulin-like growth factor 1 receptor (IGF-1R), in a sub
233 cancer who had an exceptional response to an insulin-like growth factor 1 receptor (IGF-1R)-specific
235 e mitogenic and antiapoptotic signaling from insulin-like growth factor 1 receptor (IGF-IR), insulin
236 ession in this lineage and was stimulated by insulin-like growth factor 1 receptor (IGF1R) activation
237 in asthma, but little is known about how the insulin-like growth factor 1 receptor (IGF1R) affects as
238 ciated with increased phosphorylation of the insulin-like growth factor 1 receptor (IGF1R), which is
240 ang et al that describes a critical role for insulin-like growth factor 1 receptor in the progression
241 human IgG1 monoclonal antibody targeting the insulin-like growth factor 1 receptor in thymic epitheli
243 elegans, the highly conserved DAF-2/insulin/insulin-like growth factor 1 receptor signaling (IIS) pa
244 tion of the Gap 2/mitosis transition and the insulin-like growth factor 1 receptor signaling cascade
245 alized response is achieved by activation of insulin-like growth factor 1 receptor signaling complexe
246 s as an autocrine activator of the beta-cell insulin-like growth factor 1 receptor signaling pathway.
247 2 (Cyclin D2), CCND1 (Cyclin D1), and IGF1R (insulin-like growth factor 1 receptor) genes involved in
248 LY294002) signaling, but not an inhibitor of insulin-like growth factor 1 receptor, abrogated TrkC-me
249 nd downregulation of the activities of Rac1, insulin-like growth factor 1 receptor, protein kinase B,
250 t-mammalian target of rapamycin pathway, and insulin-like growth factor 1 receptor-targeted therapy h
253 rgistic antitumour activity by inhibition of insulin-like growth factor-1 receptor (IGF-1R) and mTOR.
254 actor (PlGF), induces the phosphorylation of insulin-like growth factor-1 receptor (IGF-1R) and the i
257 Increased expression or signaling from the insulin-like growth factor-1 receptor (IGF-1R) has been
258 ls activates tyrosine phosphorylation of the insulin-like growth factor-1 receptor (IGF-1R) in a time
259 abolished these effects of insulin, whereas insulin-like growth factor-1 receptor (IGF-1R) silencing
260 ifferentiation induction is dependent on the insulin-like growth factor-1 receptor (IGF-1R) survival-
261 beta-Arrestin1 is also recruited to the insulin-like growth factor-1 receptor (IGF-1R), a recept
262 nockdown by RNAi decreased expression of the insulin-like growth factor-1 receptor (IGF-1R), resultin
269 he purpose of this study was to characterize insulin-like growth factor-1 receptor (IGF1R) protein ex
272 lomerase axis, population-doubling time, and insulin-like growth factor-1 receptor expression in CSCs
273 e, telomere length, telomerase activity, and insulin-like growth factor-1 receptor expression were me
274 mmunohistochemical positivity for p4E-BP1 or insulin-like growth factor-1 receptor was statistically
275 ated fibroblast growth factor receptor-3 and insulin-like growth factor-1 receptor, and in coronary v
279 differences in the expression pattern of the insulin-like growth factor-1 receptor/mammalian target o
280 nique sequence changes in growth hormone and insulin-like growth factor 1 receptors are also observed
281 s, together with a high circulating level of insulin-like growth factor-1, represent a novel biomarke
283 with increased 17beta-estradiol but not with insulin-like growth factor 1 serum levels in miglustat-t
284 cking platform transduces the insulin/IGF-1 (insulin like growth factor 1) signal to intracellular ef
288 cts primarily by blunting the growth hormone/insulin-like growth factor-1 signaling pathway in liver.
292 growth factor, hepatocyte growth factor, and insulin-like growth factor-1, stimulating angiogenesis.
295 luding a proliferation-induced ligand, BAFF, insulin-like growth factor 1, vascular endothelial growt
296 ingulate, treatment-related changes in serum insulin-like growth factor 1 were positively correlated
297 2 saturation and plasma glucose, insulin and insulin-like growth factor-1 were positively associated
298 growth factor, hepatocyte growth factor, and insulin-like growth factor 1 when transplanted into the
299 yotube hypertrophy through the expression of insulin-like growth factor 1, which is dependent on Galp
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