ライフサイエンスコーパス: insulin-like growth factor I receptor

1 hat hMAD2 does not interact with the related insulin-like growth factor I receptor.

2 IRS-2 interacts directly with the IR and the insulin-like growth factor I receptor.

3 2, rearranged during transfection (RET), and insulin-like growth factor I receptor.

4 on molecule implicated in breast cancer, the insulin-like growth factor I receptor.

5 uch as insulin-like growth factor II and the insulin-like growth factor I receptor.

6 ptor signal transducing chain gp130 and with insulin-like growth factor-I receptor.

7 naling molecule activated by the insulin and insulin-like growth factor I receptors.

8 wn to interact with both the insulin and the insulin-like growth factor-I receptors.

9 orming growth factor beta, interferon gamma, insulin-like growth factor I receptor, activating transc

10 The different responses of CrkL and CrkII to insulin-like growth factor-I receptor activation suggest

11 sensitivity to small molecule inhibitors of insulin-like growth factor I receptor and c-Met.

12 the defects of insulin-like growth factor I-insulin-like growth factor I receptor and mitogen-activa

13 were enriched in the "CTNNB1" class, whereas insulin-like growth factor I receptor and RPS6 phosphory

14 interaction with the IR as compared with the insulin-like growth factor I receptor and that interacts

15 Levels of insulin-like growth factor-I receptor and phosphorylated

16 ns of the Drosophila insulin receptor, human insulin-like growth factor I receptor, and human insulin

17 Insulin-like growth factor-I receptor as well as the ins

18 Inhibition of AKT, TORC1/2, or insulin-like growth factor I receptor blocked AZD6244-in

19 emonstrate that inhibition of the endogenous insulin-like growth factor I receptor by stable expressi

20 or called ER2 and a constitutively activated insulin-like growth factor I receptor called NM1, both o

21 lved in breast carcinogenesis via regulating insulin-like growth factor-I receptor-dependent signalin

22 ency and selectivity over related receptors (insulin-like growth factor I receptor, epidermal growth

23 the cytoplasmic domain of an oncogenic human insulin-like growth factor I receptor (gag-IGFR) were sy

24 Because the insulin-like growth factor-I receptor has been implicate

25 Insulin-like growth factor I receptor (IGF-1R) signaling

26 The insulin-like growth factor I receptor (IGF-I-R) plays a

27 has been implicated in negatively regulating insulin-like growth factor I receptor (IGF-IR) activity.

28 An overexpressed insulin-like growth factor I receptor (IGF-IR) allows ce

29 eloped which binds specifically to the human insulin-like growth factor I receptor (IGF-IR) and inhib

30 Insulin-like growth factor I receptor (IGF-IR) and its l

31 The insulin-like growth factor I receptor (IGF-IR) and the i

32 Grb10 is an interacting partner of the insulin-like growth factor I receptor (IGF-IR) and the i

33 Hyperactivation of the insulin-like growth factor I receptor (IGF-IR) contribut

34 The insulin-like growth factor I receptor (IGF-IR) controls

35 er of this family (hSOCS-2) by utilizing the insulin-like growth factor I receptor (IGF-IR) cytoplasm

36 In addition, insulin-like growth factor I receptor (IGF-IR) endocytos

37 se embryos with a targeted disruption of the insulin-like growth factor I receptor (IGF-IR) genes) an

38 Insulin-like growth factor I receptor (IGF-IR) has been

39 Overexpression or activation of insulin-like growth factor I receptor (IGF-IR) has been

40 The insulin-like growth factor I receptor (IGF-IR) has been

41 Alterations in insulin-like growth factor I receptor (IGF-IR) have been

42 To understand the structural importance of insulin-like growth factor I receptor (IGF-IR) in mediat

43 gated the activation of STAT proteins by the insulin-like growth factor I receptor (IGF-IR) in vitro

44 Inhibition of the insulin-like growth factor I receptor (IGF-IR) is a new

45 The insulin-like growth factor I receptor (IGF-IR) is a tran

46 The insulin-like growth factor I receptor (IGF-IR) is a ubiq

47 Insulin-like growth factor I receptor (IGF-IR) is freque

48 The insulin-like growth factor I receptor (IGF-IR) is involv

49 The insulin-like growth factor I receptor (IGF-IR) is overex

50 Activation of insulin-like growth factor I receptor (IGF-IR) kinase is

51 ostulated that mutations in the gene for the insulin-like growth factor I receptor (IGF-IR) might und

52 An overexpressed insulin-like growth factor I receptor (IGF-IR) protects

53 expression of a wild-type (but not a mutant) insulin-like growth factor I receptor (IGF-IR) protects

54 Herein, we have focused on the role of insulin-like growth factor I receptor (IGF-IR) signaling

55 d receptor clustering and is associated with insulin-like growth factor I receptor (IGF-IR), a recept

56 t Id gene expression can be regulated by the insulin-like growth factor I receptor (IGF-IR), a recept

57 tem, we have isolated a new substrate of the insulin-like growth factor I receptor (IGF-IR), identifi

58 a cascade of events, including activation of insulin-like growth factor I receptor (IGF-IR), phosphat

59 ole of protein kinase C-delta (PKC-delta) in insulin-like growth factor I receptor (IGF-IR)-mediated

60 onal immunoglobulin G1 antibody that targets insulin-like growth factor I receptor (IGF-IR).

61 n the next promising therapeutic target, the insulin-like growth factor I receptor (IGF-IR).

62 strated that overexpression of the wild type insulin-like growth factor I receptor (IGF-IRWT) in 32D

63 Insulin-like growth factor I receptors (IGF-IRs) are ove

64 Here, we report that insulin-like growth factor-I receptor (IGF-IR) activatio

65 Estrogen can increase insulin-like growth factor-I receptor (IGF-IR) and insul

66 kinase plasminogen activator-1 (uPA) and the insulin-like growth factor-I receptor (IGF-IR) are assoc

67 Epidermal growth factor receptor (EGFR) and insulin-like growth factor-I receptor (IGF-IR) can coope

68 Overexpression of insulin-like growth factor-I receptor (IGF-IR) correlate

69 A role for hyperinsulinemia and increased insulin-like growth factor-I receptor (IGF-IR) expressio

70 Insulin-like growth factor-I receptor (IGF-IR) gene expr

71 Overexpression of insulin-like growth factor-I receptor (IGF-IR) has been

72 Insulin-like growth factor-I receptor (IGF-IR) hyperstim

73 Overexpression and enhanced activity of insulin-like growth factor-I receptor (IGF-IR) in divers

74 ecorin core protein can bind to and activate insulin-like growth factor-I receptor (IGF-IR) in endoth

75 he growth factor receptors erbB2, erbB3, and insulin-like growth factor-I receptor (IGF-IR) in trastu

76 Knockdown of InsR and/or insulin-like growth factor-I receptor (IGF-IR) inhibited

77 Insulin-like growth factor-I receptor (IGF-IR) is a cell

78 The insulin-like growth factor-I receptor (IGF-IR) is a key

79 Insulin-like growth factor-I receptor (IGF-IR) is a prot

80 Insulin-like growth factor-I receptor (IGF-IR) is freque

81 Signaling through the insulin-like growth factor-I receptor (IGF-IR) is implic

82 The activated insulin-like growth factor-I receptor (IGF-IR) is implic

83 The insulin-like growth factor-I receptor (IGF-IR) monoclona

84 shown by several groups as well as ours that insulin-like growth factor-I receptor (IGF-IR) overexpre

85 The insulin-like growth factor-I receptor (IGF-IR) plays a c

86 sion resulted in a 44-60% reduction in total insulin-like growth factor-I receptor (IGF-IR) protein l

87 Increased expression of the insulin-like growth factor-I receptor (IGF-IR) protein-t

88 oding a dominant-negative, kinase-dead human insulin-like growth factor-I receptor (IGF-IR) that is e

89 fibronectin, a major ECM component, engages insulin-like growth factor-I receptor (IGF-IR) to inhibi

90 ent study, we show that HER-2 interacts with insulin-like growth factor-I receptor (IGF-IR) uniquely

91 Activation of the insulin-like growth factor-I receptor (IGF-IR) was recen

92 ammalian target of rapamycin (mTOR) pathway, insulin-like growth factor-I receptor (IGF-IR), and mito

93 Agents targeting insulin-like growth factor-I receptor (IGF-IR), includin

94 we demonstrate that a specific inhibitor of insulin-like growth factor-I receptor (IGF-IR), NVP-AEW5

95 intact EWS and FLI-1 domains as well as the insulin-like growth factor-I receptor (IGF-IR).

96 The tyrosine kinase activity of insulin-like growth factor I receptor (IGF1R) is under t

97 ved growth factor receptor beta (Pdgfrb) and insulin-like growth factor I receptor (Igf1r) on T-ALL c

98 The insulin-like growth factor I receptor (IGFIR) and HER2 d

99 increased copy number at chromosome 15q26.3 insulin-like growth factor I receptor (IGFIR) and tumor

100 epsilon isoform of 14-3-3 interacts with the insulin-like growth factor I receptor (IGFIR) and with i

101 nteract with the intracellular domain of the insulin-like growth factor-I receptor (IGFIR).

102 g for oncogenic Gag-insulin receptor and Gag-insulin-like growth factor I receptor (IGFR) fusion prot

103 Insulin-like growth factor I receptor (IGFR) plays an im

104 t epidermal growth factor receptor (EGFR) or insulin-like growth factor-I receptor (IGFR).

105 ptor [EGFR], Ros, insulin receptor [IR], and insulin-like growth factor I receptor [IGFR]) led to tyr

106 tudy demonstrates that the activation of the insulin-like growth factor-I receptor induces changes in

107 a transgenic mouse with a dominant-negative insulin-like growth factor-I receptor (KR-IGF-IR) specif

108 f the VHL gene product (pVHL) can inhibit on insulin-like growth factor-I receptor-mediated signaling

109 on of Crk, but not Shc, in NIH-3T3 parental, insulin-like growth factor-I receptor-overexpressing and

110 tus, including MDA-MB-231, BT474, SKBR3, and insulin-like growth factor-I receptor-overexpressing SKB

111 l transducer and activator of transcription, insulin-like growth factor I receptor pathway, fibroblas

112 the establishment and maintenance of Ros and insulin-like growth factor I receptor PTK-induced cell t

113 Analysis of the proximal promoter of the insulin-like growth factor I receptor revealed a novel A

114 deprivation affects AKT activity by reducing insulin-like growth factor I receptor sensitivity to gro

115 responsible for continued activation of the insulin-like growth factor-I receptor, suggesting a role

116 he growth inhibition induced by blocking the insulin-like growth factor-I receptor suggests that IGF-

117 Insulin-like growth factor-I receptor targeted monoclona

118 that IGF-II-initiated signaling through the insulin-like growth factor-I receptor targets transcript

119 -phosphorylated receptors such as the IR and insulin-like growth factor I receptor via multiple indep

120 major signaling molecule for the insulin and insulin-like growth factor I receptors, which transduces