ライフサイエンスコーパス: insulin-like growth factor receptor

1 oward the insulin receptor and/or the type 1 insulin-like growth factor receptor.

2 mouse embryo fibroblasts null for the type 1 insulin-like growth factor receptor.

3 y between the insulin receptor and mitogenic insulin-like growth factor receptor.

4 to activate PI3K signaling downstream of the insulin-like growth factor receptor.

5 ecycling and participates in trafficking the insulin-like growth factor receptor.

6 may resemble the cysteine-rich region of the insulin-like growth factor receptor.

7 ural homology to domains found in the type I insulin-like growth factor receptor.

8 tyrosine kinases, including the insulin and insulin-like growth factor receptors.

9 beta (Il1b), estrogen receptor alpha (Esr1), insulin like growth factor receptor 1 (Igf1), and glucoc

10 the MAPK pathway, PI3Kbeta, and PI3Kalpha or insulin-like growth factor receptor 1 (IGF1R) synergisti

11 receptor (EGFR) and insulin receptor (InsR)/insulin-like growth factor receptor 1 (IGF1R), as well a

12 omoting effects of IGF2 were mediated by the insulin-like growth factor receptor 1 and phosphoinositi

13 pathway as targets of miR-378: MAPK1 itself, insulin-like growth factor receptor 1, growth factor rec

14 actor receptor 3; NVP-ADW742, which inhibits insulin-like growth factor receptor 1; and PTK787, which

15 Insulin-like growth factor receptor-1 (IGF-1R)-bearing f

16 arises through an enhanced cross talk of the insulin-like growth factor receptor-1 (IGF-1R)/insulin r

17 betaE2 activated retinal IRbeta, but not the insulin-like growth factor receptor-1, and produced a tr

18 ression of ErbB2, p-ErbB2, Erk1/2, p-Erk1/2, insulin-like growth factor receptor-1, p70 S6 kinase, an

19 In addition, the murine insulin receptor and insulin-like growth factor receptor 5' UTRs support cap-

20 and CrkL phosphorylation are associated with insulin-like growth factor receptor activation in cultur

21 ative inhibition, independent of insulin and insulin-like growth factor receptor activation.

22 the gene daf-2, a homolog of the insulin and insulin-like growth factor receptors, age more slowly th

23 Conversely, the insulin-like growth factor receptor and EGFR, which inte

24 teins, including Akt, STAT3, JNK, and type I insulin-like growth factor receptor, and it down-regulat

25 teinase-3, epidermal growth factor receptor, insulin-like growth factor receptor, and phosphatidylino

26 3T3 cells null for the type 1 insulin-like growth factor receptor are refractory to st

27 kinase activity associated with insulin and insulin-like growth factor receptors, because acute expo

28 ent PCa and indicate that loss of the type 1 insulin-like growth factor receptor contributes to PCa p

29 4 seems to exert RIBEs by acting through the insulin-like growth factor receptor DAF-2.

30 We have recently discovered that the insulin-like growth factor receptor I (IGF-IR) is up-reg

31 The insulin-like growth factor receptor I (IGF-IR) plays an

32 The insulin-like growth factor receptor I (IGF-IR) plays an

33 ) cell line demonstrated an up-regulation of insulin-like growth factor receptor I (IGFR-I) levels on

34 y activates an insulin receptor (IR) but not insulin-like growth factor receptor-I or other receptor

35 rotein that induces apoptosis utilizing both insulin-like growth factor receptor (IGF)-dependent and

36 em particularly appealing for further study: insulin-like growth factor receptor (IGF-1R) and histone

37 ession and/or function of multiple levels of insulin-like growth factor receptor (IGF-1R) and interle

38 Inhibition of type 1 insulin-like growth factor receptor (IGF-1R) enhances tu

39 The type 1 insulin-like growth factor receptor (IGF-1R) is often ov

40 Signaling through the type 1 insulin-like growth factor receptor (IGF-1R) occurs in m

41 The type 1 insulin-like growth factor receptor (IGF-1R) tyrosine ki

42 The type 1 insulin-like growth factor receptor (IGF-1R), activated

43 late other types of receptors, including the insulin-like growth factor receptor (IGF-1R), although t

44 autophosphorylation transition in the type I insulin-like growth factor receptor (IGF-1R).

45 ric and competitive inhibitors of the type-I insulin-like growth factor receptor (IGF-1R).

46 ), glucose transporter-4 (GLUT-4) and type 1 insulin-like growth factor receptor (IGF-1R).

47 Reduced protein levels of the insulin-like growth factor receptor (IGF-1Rbeta) were ob

48 The insulin-like growth factor receptor (IGF-IR) and insulin

49 having a PTEN mutation, low levels of type 1 insulin-like growth factor receptor (IGF-IR) and no IRS-

50 Prostate cancer cells express type I insulin-like growth factor receptor (IGF-IR) and prostat

51 RS-1), a docking protein for both the type 1 insulin-like growth factor receptor (IGF-IR) and the ins

52 Activation of the type I insulin-like growth factor receptor (IGF-IR) blocks osmo

53 We report here that activation of the type I insulin-like growth factor receptor (IGF-IR) by IGF-I in

54 Autocrine stimulation of the type I insulin-like growth factor receptor (IGF-IR) by IGF-II i

55 Type I insulin-like growth factor receptor (IGF-IR) can transfo

56 ls in which the overexpression of the type I insulin-like growth factor receptor (IGF-IR) enhanced th

57 Our laboratory has shown that type I insulin-like growth factor receptor (IGF-IR) expression

58 yos with a targeted disruption of the type 1 insulin-like growth factor receptor (IGF-IR) genes.

59 In recent years, the type 1 insulin-like growth factor receptor (IGF-IR) has emerged

60 tial burst of cell proliferation, the type 1 insulin-like growth factor receptor (IGF-IR) induces gra

61 The type 1 insulin-like growth factor receptor (IGF-IR) is a recept

62 The type I insulin-like growth factor receptor (IGF-IR) is an integ

63 Preclinical evidence that targeting the insulin-like growth factor receptor (IGF-IR) is effectiv

64 The type I insulin-like growth factor receptor (IGF-IR) is known to

65 The type 1 insulin-like growth factor receptor (IGF-IR) is known to

66 Deletion of the type 1 insulin-like growth factor receptor (IGF-IR) or of the i

67 THe type 1 insulin-like growth factor receptor (IGF-IR) plays an im

68 The type 1 insulin-like growth factor receptor (IGF-IR) plays an im

69 t in AsPC-1 pancreatic adenocarcinoma cells, insulin-like growth factor receptor (IGF-IR) regulates V

70 The type 1 insulin-like growth factor receptor (IGF-IR) sends a str

71 Type I insulin-like growth factor receptor (IGF-IR) tyrosine ki

72 The type 1 insulin-like growth factor receptor (IGF-IR), activated

73 and expression of beta1A integrin and type 1 insulin-like growth factor receptor (IGF-IR), known to c

74 blasts (MEFs) that do not express the type 1 insulin-like growth factor receptor (IGF-IR).

75 e-1 (IRS-1), a major substrate of the type 1 insulin-like growth factor receptor (IGF-IR).

76 ent work demonstrated that activation of the insulin-like growth factor receptor (IGF-IR)/insulin rec

77 s, which are 3T3-like cells devoid of type 1 insulin-like growth factor receptors (IGF-IRs).

78 novel cross-talk paradigm between the type I insulin-like growth factor receptor (IGF1R) and epiderma

79 The type I insulin-like growth factor receptor (IGF1R) and insulin

80 l lines of evidence now indicate that type 1 insulin-like growth factor receptor (IGF1R) function may

81 Inhibitors of the insulin-like growth factor receptor (IGF1R) have been co

82 e found that dasatinib combined with MET and insulin-like growth factor receptor (IGF1R) inhibitors h

83 Type 1 insulin-like growth factor receptor (IGF1R) is a membran

84 The type I insulin-like growth factor receptor (IGF1R) is involved

85 The type 1 insulin-like growth factor receptor (IGF1R) is often ove

86 The type 1 insulin-like growth factor receptor (IGF1R) is overexpre

87 The type 1 insulin-like growth factor receptor (IGF1R) is required

88 The type 1 insulin-like growth factor receptor (IGF1R) mediates tum

89 cancer cells for efficacy against the type 1 insulin-like growth factor receptor (IGF1R) mRNA and the

90 Inhibition of the type 1 insulin-like growth factor receptor (IGF1R) reduces the

91 The type I insulin-like growth factor receptor (IGF1R) regulates mu

92 Instead, they have shown activated insulin-like growth factor receptor (IGF1R) signaling as

93 nd population studies have implicated type I insulin-like growth factor receptor (IGF1R) signaling in

94 s whose tumors express immunoreactive type I insulin-like growth factor receptor (IGF1R), a key media

95 lly human monoclonal antibody against type-1 insulin-like growth factor receptor (IGF1R).

96 dermal growth factor receptor (EGFR) and the insulin-like growth factor receptor (IGFR) have been imp

97 dermal growth factor receptor (EGFR) and the insulin-like growth factor receptor (IGFR) have been imp

98 mediated shedding of a factor activating the insulin-like growth factor receptor (IGFR).

99 tometry, and activation of components of the insulin-like growth factor receptor (IGFR)/Akt pathway w

100 within Grb10 that interacts with the IR and insulin-like growth factor receptor in a kinase-dependen

101 24), a novel small-molecule inhibitor of the insulin-like growth factor receptor kinase with equal po

102 eceptor (insulin receptor knockout (IRKO) or insulin-like growth factor receptor knockout (IGFRKO)).

103 tic index, and were more highly positive for insulin-like growth factor receptor phosphorylation.

104 get of rapamycin; insulin-like growth factor/insulin-like growth factor receptor; poly (ADP-ribose) p

105 receptor (PDGFR)alpha, MET, insulin receptor/insulin-like growth factor receptor signaling, and SRC f

106 In contrast, the type 1 insulin-like growth factor receptor, thought to play a r

107 let-derived growth factor (PDGF), ErbB2, and insulin-like growth factor receptor transcripts, yet LPA

108 (OAscFab-IgG) antibody format targeting the insulin-like growth factor receptor type I (IGF-1R) and

109 eta receptor type II, hMSH3, BAX, hMSH6, and insulin-like growth factor receptor type II.