ライフサイエンスコーパス: insulin-sensitive

1 that Pparg(P465L/+)Ins2(Akita/+) livers are insulin sensitive.

2 ts suggest that skeletal muscles are equally insulin sensitive.

3 ed normal amounts of adipose tissue and were insulin sensitive.

4 rably to Step II diets than do those who are insulin sensitive.

5 significantly decreased body fat, and remain insulin sensitive.

6 rtion of African-American NIDDM subjects are insulin sensitive.

7 of severely obese (BMI >40) individuals are insulin sensitive.

8 at hGLUT4 TG mice fed an HFD remained highly insulin sensitive.

9 nKO mice remained fully glucose tolerant and insulin sensitive.

10 ated intramyocellular lipids, yet are highly insulin sensitive.

11 e of the reasons that these tissues remained insulin sensitive.

12 e type 1 resist diet-induced obesity and are insulin-sensitive.

13 betic subjects who were insulin-resistant or insulin-sensitive.

14 Thus, HF/HS+INDO-fed mice remained insulin-sensitive.

15 mice with JNK-deficient macrophages remained insulin-sensitive.

16 tive (34.3 +/- 13.1 micro g/ml) or nonobese, insulin-sensitive (29.8 +/- 15.3 micro g/ml) subjects.

17 5 micro g/ml) as compared with either obese, insulin-sensitive (34.3 +/- 13.1 micro g/ml) or nonobese

18 We show here that in insulin-sensitive 3T3-L1 adipocytes and other cultured c

19 cells, Glut4 is predominantly found in small insulin-sensitive 60-70 S membrane vesicles that may or

20 talytic subunit, is prominently expressed in insulin-sensitive adipose cells.

21 in resistant high fat diet (HFD) mice become insulin-sensitive after switching from HFD to normal cho

22 hiPSC-derived adipocytes are insulin sensitive and display beige-specific markers and

23 Our results show that miR-155KO animals are insulin sensitive and glucose tolerant compared to contr

24 They were also leaner and more insulin sensitive and had lower liver fat contents.

25 adipocyte triglyceride levels typically are insulin sensitive and have normal or low liver and circu

26 advanced age, these clones are euglycaemic, insulin sensitive and normotensive.

27 0 obese individuals (22%) were classified as insulin sensitive and obese (IS-obese).

28 the hypothesis that B6-Ins2Akita/+ mice are insulin sensitive and provide an excellent model for isl

29 istinguish physiological differences between insulin-sensitive and -resistant individuals.

30 between (1) heavy and thin adolescents; (2) insulin-sensitive and insulin-resistant adolescents; and

31 esponses to dipyridamole were similar in the insulin-sensitive and insulin-resistant groups.

32 ly affects hepatic phosphorus metabolites in insulin-sensitive and insulin-resistant humans.

33 st of the studies comparing fat oxidation in insulin-sensitive and insulin-resistant individuals have

34 downstream signaling in glucose transport in insulin-sensitive and insulin-resistant mature skeletal

35 Both insulin-sensitive and insulin-resistant nondiabetic subg

36 or UCP2, UCP3S, or UCP3L mRNA levels between insulin-sensitive and insulin-resistant nondiabetic subg

37 are few prospective data on the prognosis of insulin-sensitive and insulin-resistant normal-weight (N

38 Recent studies in which adipose tissue of insulin-sensitive and insulin-resistant patients with se

39 were 0.4%, 6.3%, and 3.3%, respectively, in insulin-sensitive and normal-weight (IS-NW) individuals

40 Lean insulin-sensitive and obese insulin-resistant subjects (

41 Podocytes are insulin-sensitive and take up glucose in response to ins

42 rence of > or = 600% exists between the most insulin-sensitive and the most insulin-resistant persons

43 The IPGR group remained lean, euglycemic, insulin sensitive, and active while maintaining metaboli

44 Acsl1(M-/-) mice were more insulin sensitive, and, during an overnight fast, their

45 ay be normalized by transfusion of APCs from insulin-sensitive animals but not from insulin-resistant

46 The insulin-sensitive, anti-inflammatory phenotype of KO-DIO

47 utes, showing that the output of leptin- and insulin-sensitive ARH neurons that ordinarily stimulate

48 The SRA(-/-) mice are more insulin sensitive, as evidenced by reduced fasting insul

49 ately 50% less fat mass and were 2-fold more insulin sensitive, as measured by hyperinsulinemic-eugly

50 n obese insulin-resistant compared with lean insulin-sensitive baboons.

51 ses an increase in the production of EDNO in insulin-sensitive but not insulin-resistant subjects.

52 % sucrose fraction by 2.8-fold over basal in insulin-sensitive but only by 1.5-fold in both insulin-r

53 SCD1(-/-) mice on an HFD remain insulin-sensitive, but develop glucose intolerance and i

54 valuated their biological effects in several insulin sensitive cell lines.

55 whether increased expression of PTP1B in an insulin-sensitive cell type could contribute to insulin

56 NA appears as a 9-kb transcript, enriched in insulin-sensitive cells and tissues, likely transcribed

57 ing molecules that mediate insulin action in insulin-sensitive cells.

58 enic signaling similar to that described for insulin-sensitive cells.

59 roposed for this proinflammatory cytokine in insulin-sensitive cells.

60 insulin-receptor mechanism as described for insulin-sensitive cells.

61 tection of insulin was accomplished using an insulin-sensitive chemically modified electrode.

62 In this study, we found smokers were less insulin sensitive compared with controls, which increase

63 bited better glucose tolerance and were more insulin sensitive compared with wild-type controls.

64 zed IRAP protein traffics to the perinuclear insulin-sensitive compartment and acquires insulin sensi

65 SP rat model compared with the normotensive, insulin-sensitive control strain, Wistar-Kyoto (WKY).

66 l x g(-1) x min(-1), P = 0.02) compared with insulin-sensitive control subjects (96.1 +/- 16.3 nmol x

67 n the insulin-resistant subjects than in the insulin-sensitive control subjects (P<0.001) and was ass

68 fspring of patients with type 2 diabetes and insulin-sensitive control subjects matched for age, heig

69 nt offspring of type 2 diabetic patients and insulin-sensitive control subjects underwent (13)C MRS s

70 obese insulin-resistant individuals than in insulin-sensitive control subjects.

71 age-weight-body mass index-activity-matched, insulin-sensitive, control subjects.

72 and bottom pellet in diabetics compared with insulin-sensitive controls, without any differences in m

73 oted in the men, whereas the women were more insulin sensitive, demonstrating further dissociation be

74 trated abdominal lipodystrophy, and remained insulin-sensitive despite having a marked impairment in

75 rd diet, mice overexpressing ChREBP remained insulin sensitive, despite increased expression of genes

76 A mouse that spontaneously developed insulin-sensitive diabetes without beta-cell autoimmunit

77 Using this definition, the proportion of insulin-sensitive diabetic subjects was very low in all

78 P-I-KO mice remain more glucose tolerant and insulin sensitive during high-fat-diet feeding.

79 The lean, hypermetabolic, and insulin-sensitive E2+/p- phenotype appears to result fro

80 rtment model of GLUT1 recycling involving an insulin sensitive endocytosis step in common with the GL

81 Adipose tissue lipoprotein lipase is an insulin-sensitive enzyme.

82 We demonstrate that DZ regulates key insulin-sensitive enzymes involved in regulation of adip

83 d us to investigate the effects of DZ on key insulin-sensitive enzymes regulating adipose tissue meta

84 This corresponded with insulin-sensitive expression changes in enzymes of EC me

85 variance), but not in FH+, as even the most insulin-sensitive FH+ offspring had diminished endotheli

86 We sought to examine insulin-sensitive food intake behavior and neuroendocrin

87 Here, we report that SIN3A is the insulin-sensitive FOXO1 corepressor of glucokinase.

88 and beta3-adrenergic receptor), other novel insulin-sensitive genes were also identified (e.g. Egr-1

89 3T3-J2 murine embryonic fibroblasts maintain insulin-sensitive glucose metabolism for several weeks.

90 th liver an important site of alterations in insulin-sensitive glucose production.

91 vestigate the ability of PPARgamma to confer insulin-sensitive glucose transport to a variety of muri

92 C/EBPalpha is required for establishment of insulin-sensitive glucose transport.

93 ivo, due primarily to the recruitment of the insulin-sensitive glucose transporter (GLUT4) to the pla

94 onavir were investigated in mice lacking the insulin-sensitive glucose transporter GLUT4 (G4KO).

95 bGAP AS160/TBC1D4 controls exocytosis of the insulin-sensitive glucose transporter Glut4 in adipocyte

96 ulin signaling is that they both express the insulin-sensitive glucose transporter Glut4.

97 transport by promoting translocation of the insulin-sensitive glucose transporter isoform 4 (GLUT4)

98 the regional and cellular expression of the insulin-sensitive glucose transporter, GLUT4, in rodent

99 The expression of the insulin-sensitive glucose transporter, GLUT4, is signifi

100 led to the transcriptional induction of the insulin-sensitive glucose transporter, GLUT4.

101 particularly in the regulation of GLUT4, the insulin-sensitive glucose transporter, in the AT of PCOS

102 Evidence suggests that insulin-sensitive glucose transporters (GLUTs) other tha

103 6 h) resulted in a substantial inhibition of insulin-sensitive glucose uptake.

104 them to the adipocyte phenotype and restores insulin-sensitive glucose uptake.

105 stigate whether GLUT12 may represent another insulin-sensitive GLUT, transgenic (TG) mice that overex

106 dence that GLUT12 represents a novel, second insulin-sensitive GLUT.

107 alpha(i2) regulates the translocation of the insulin-sensitive GLUT4 glucose transporter in skeletal

108 The insulin-sensitive GLUT4 isoform was localized to vascula

109 translocation, probably by way of tethering insulin-sensitive Glut4 vesicles at an as yet unknown in

110 Insulin-sensitive Glut4 vesicles did not contain either

111 nes, confirming that Vti1a is a component of insulin-sensitive GLUT4-containing vesicles.

112 groups, as well as reasons for believing the insulin-sensitive group will be less disease prone.

113 differences between insulin-resistant versus insulin-sensitive groups than the expression of genes in

114 (T-IS), thin insulin-resistant (T-IR), heavy insulin-sensitive (H-IS), and heavy insulin-resistant (H

115 Obese Tg mice remained insulin sensitive, had increased glucose uptake by adipo

116 ed a high-fat diet, although obese, remained insulin sensitive, had lower free fatty acid in plasma,

117 nerates a burst of intracellular H(2)O(2) in insulin-sensitive hepatoma and adipose cells that is ass

118 Transcripts from duodenal samples of insulin-sensitive (HOMA-IR < 3, n = 9) and insulin-resis

119 ucose positron emission tomography, in seven insulin-sensitive (homeostasis model assessment of insul

120 insulin-resistant (HR 1.50, P=0.01) but not insulin-sensitive (HR 1.02, P=0.9) participants.

121 Young, lean, insulin-sensitive humans (CONs) [mean +/- SD body mass i

122 sulin-resistant humans compared to ratios in insulin-sensitive humans, indicating that higher apo-RBP

123 insulin resistance, skeletal muscle is more insulin sensitive in BKS-db than in B6-db mice.

124 besity to wild-type littermates but remained insulin sensitive in skeletal muscle.

125 HFD mice rapidly become insulin-sensitive in all major insulin-target tissues, i

126 pothesis that some signaling pathways remain insulin-sensitive in metabolically insulin-resistant adi

127 One gene that remained insulin-sensitive in the insulin-resistant adipocytes is

128 fat (P < 0.0002) while remaining euglycemic, insulin sensitive, inactive, and exhibiting metabolic in

129 d from vastus lateralis muscle from lean and insulin-sensitive individuals and from obese and insulin

130 R < 0.05) between muscle or adipose cells of insulin-sensitive individuals and those of insulin-resis

131 ry markers and non-HDL cholesterol levels in insulin-sensitive individuals but not in lean or obese i

132 ish adipose tissue of insulin resistant from insulin-sensitive individuals with severe obesity.

133 rsus 1.68 mg/L [1.13 to 2.49]; P=0.018) than insulin-sensitive individuals, but individuals with decr

134 n adipose tissue of insulin-resistant versus insulin-sensitive individuals, who were matched for body

135 a of diabetic patients compared with that of insulin-sensitive individuals.

136 itochondrial physiology toward that of lean, insulin-sensitive individuals.

137 s do type II diabetic patients compared with insulin-sensitive individuals.

138 nd this effect is particularly manifested in insulin-sensitive individuals.

139 asured in liver biopsy samples obtained from insulin sensitive, insulin resistant, and untreated T2DM

140 and serum amino acids were determined among insulin-sensitive, insulin-resistant, and type 2 diabeti

141 The insulin-sensitive intracellular Ca2+ pool differs pharma

142 Recently, we purified three distinct insulin-sensitive intracellular GLUT4 compartments (G4T(

143 It was found in all of the three insulin-sensitive intracellular GLUT4 compartments, and

144 tantial number of overweight persons who are insulin sensitive is relatively minimal.

145 muscle Rad expression in well-characterized insulin sensitive (IS) and insulin resistant (IR) subjec

146 gregated as insulin resistant (IR; HF+IR) or insulin sensitive (IS; HF+IS) compared with control (CON

147 e (GDR) during hyperinsulinemic clamps in 56 insulin sensitive (IS; mean +/- SD: GDR 15.8 +/- 2.0 mg.

148 To test the hypothesis that obese, insulin-sensitive (IS) individuals possess adaptive adip

149 type 2 diabetes mellitus (DM) compared with insulin-sensitive (IS) individuals.

150 ssified as insulin-resistant (IR; n = 12) or insulin-sensitive (IS; n = 10), determined by hyperinsul

151 d order, nondiabetic subjects (classified as insulin-sensitive [IS] [n = 64] or insulin-resistant [IR

152 The insulin-sensitive isoform of the glucose transporting pr

153 Young ( approximately 23 years) insulin-sensitive lean and insulin-resistant obese men a

154 the insulin-resistant ZDF rats but not from insulin-sensitive lean Zucker rats.

155 MI) and insulin sensitivity index (SI): lean insulin sensitive (LIS), mean+/-SEM BMI, 23.2+/-0.3 kg/m

156 The rise in LDL with egg feeding in lean insulin-sensitive (LIS) participants is 2- and 3-fold gr

157 men, 101 women), a priori classified as lean insulin-sensitive (LIS, n = 56), lean insulin-resistant

158 Using an insulin-sensitive liver cell line, we show that localiza

159 These data indicate that the insulin-sensitive membrane compartment that sequesters G

160 tion of different fatty acid sources between insulin-sensitive men and women.

161 r in the insulin-resistant compared with the insulin-sensitive men are those derived from splanchnic

162 Insulin-resistant and insulin-sensitive men had similar postprandial chylomicr

163 atidylinositol 3-kinase and regulate various insulin-sensitive metabolic processes.

164 g of a novel PI 3-kinase, p170, from cDNA of insulin-sensitive mouse 3T3-L1 adipocytes.

165 of oral administration of ACE inhibitors on insulin-sensitive muscle glucose transport activity.

166 In insulin-sensitive muscle, caCaMKKalpha increased basal i

167 te glucose uptake additively with insulin in insulin-sensitive muscle, in the basal state in insulin-

168 oxical, this phenomenon is characteristic of insulin-sensitive myofibers and suggests that DGAT1 play

169 ose homeostasis in the face of fewer type I (insulin-sensitive) myofibres.

170 their insulin sensitivity index (S(I)): lean insulin sensitive (n = 65), lean insulin resistant (n =

171 Insulin-resistant (n = 11) and insulin-sensitive (n = 11) men and women (n = 6) were gi

172 Postmenopausal women were divided into insulin-sensitive (n = 15) and insulin-resistant (n = 15

173 cipants into insulin-resistant (IR, n=20) or insulin-sensitive (n=18) groups, similar in terms of mea

174 We conclude that the number of insulin-sensitive NIDDM subjects is low and similar amon

175 t obese (MAO) subjects, metabolically normal insulin-sensitive obese (MNO) subjects, and lean subject

176 ce deficient in CB1R or SCD1 remain lean and insulin-sensitive on an HFD, suggesting a functional lin

177 KI), and patients were further classified as insulin sensitive or insulin resistant.

178 2 and impaired mTorc2/Akt signaling in other insulin-sensitive organs, leading to insulin resistance

179 Insulin-sensitive organs, overburdened by high concentra

180 These mice are also leaner and more insulin-sensitive owing to increased energy expenditure.

181 12 randomly selected, nonobese, nondiabetic, insulin-sensitive participants in a population-based stu

182 nic groups and between insulin-resistant and insulin-sensitive participants individually and using ge

183 These findings suggest that modification of insulin-sensitive pathways can be therapeutically benefi

184 ynaptic plasticity through the impairment of insulin-sensitive pathways regulating neuronal survival,

185 sis (proteostasis) due to hyperactivation of insulin-sensitive pathways such as protein synthesis.

186 st increased by 47.6% from resting values in insulin-sensitive patients and by 14.4% in insulin-resis

187 were relatively overexpressed in adipose of insulin-sensitive patients.

188 ulin-stimulated glucose clearance rates into insulin-sensitive peripheral tissues were measured using

189 egulated isoform in these cells, as it is in insulin-sensitive peripheral tissues, such as muscle.

190 al Sorbs1-null macrophages, we show that the insulin-sensitive phenotype can be transferred to wild-t

191 mechanism for the in vivo anti-inflammatory insulin-sensitive phenotype observed in mice with macrop

192 hepatic overexpression of TRB-3 reversed the insulin-sensitive phenotype of PGC-1-deficient mice.

193 Together, our data identify Sac3 as an insulin-sensitive phosphatase whose down-regulation incr

194 To determine the insulin-sensitive phosphorylation sites, phosphocalmodul

195 gene, termed PDK4, in insulin-resistant and insulin-sensitive Pima Indians, and detected five DNA va

196 Incubation of the insulin-sensitive rat hepatoma Fao cells with bacterial

197 These studies demonstrate a chronic insulin-sensitive regulation of GLUT4 in rodent brain an

198 hus diabetic gastropathy in mice reflects an insulin-sensitive reversible loss of nNOS.

199 The insulin-sensitive rise in [Ca2+]i moves into the distal

200 Smokers were less insulin sensitive (S(i)) compared with nonsmokers (S(i)

201 We defined the proportion of insulin-sensitive (S(I)) subjects as > or =1.61 min-1 x

202 The insulin-sensitive Sac3 pool likely controls a discrete P

203 Surprisingly, CGI-58 knockdown mice remain insulin-sensitive, seemingly dissociating DAG from the d

204 The PNGR group was insulin sensitive, similar to IPGR, but less active whil

205 Studies to identify the insulin-sensitive sites of phosphorylation reveal that a

206 ole-body glucose metabolism by acting on the insulin-sensitive skeletal muscle glucose transport syst

207 In insulin-sensitive skeletal muscle, the expression of con

208 )) or nonobese (<27.0 kg/m(2)) and as either insulin sensitive (SSPG <100 mg/dl) or insulin resistant

209 ied the cohort into insulin-resistant versus insulin-sensitive subgroups based on homeostasis model a

210 rom insulin-resistant subjects compared with insulin-sensitive subjects (all P < 0.05).

211 ects (with BMI <30 kg/m2), the proportion of insulin-sensitive subjects (S(I) > or =1.61 min-1 x micr

212 Using this approach, insulin-sensitive subjects demonstrated a twofold higher

213 = 0.60, P < 0.02), suggesting that the most insulin-sensitive subjects had the greatest enhancement

214 Two groups of lean insulin-sensitive subjects underwent euglycemic-hyperins

215 Finally, adiponectin levels in insulin-sensitive subjects varied to a significantly gre

216 late GSIS in insulin-resistant compared with insulin-sensitive subjects, 10 participants with impaire

217 adipose tissue lipin expression is found in insulin-sensitive subjects, and lipin-beta expression in

218 In cells from insulin-sensitive subjects, insulin augmented GSV tether

219 +/- 1.1 micro g/ml in insulin-resistant and insulin-sensitive subjects, respectively; P < 0.0005).

220 ssion levels of both lipin isoforms in lean, insulin-sensitive subjects.

221 d approximately threefold above those of the insulin-sensitive subjects.

222 ng muscle mRNA from insulin-resistant versus insulin-sensitive subjects.

223 s have greater amounts of body fat than lean insulin-sensitive subjects.

224 e intestine of insulin-resistant compared to insulin-sensitive subjects.

225 higher in insulin-resistant subjects than in insulin-sensitive subjects.

226 e intestine of insulin-resistant compared to insulin-sensitive subjects: the transcripts of the insul

227 lin sensitivity (31 insulin-resistant and 31 insulin-sensitive subjects; 40 were European American an

228 port process features characteristics of the insulin-sensitive system Nm transporter.

229 insulin-resistant adolescents; and (3) thin insulin-sensitive (T-IS), thin insulin-resistant (T-IR),

230 Wnt10b-Ay mice are more glucose tolerant and insulin sensitive than A(y) controls, perhaps due to red

231 mice have lower plasma insulin and are more insulin sensitive than AKR mice.

232 mass, Txnip knockout mice were markedly more insulin sensitive than controls, and augmented glucose t

233 standard chow and HFD, SINKO mice were more insulin sensitive than Sirt1(f/f) mice.

234 Adults born preterm were less insulin sensitive than those born at term (19.0 +/- 2.5

235 sponse to intravenous glucose, and were more insulin sensitive than those with type 2 diabetes.

236 iet (HFD), Chga-KO mice (KO-DIO) remain more insulin sensitive than wild-type DIO (WT-DIO) mice.

237 e, MacT3 mice were more glucose tolerant and insulin sensitive than wild-type mice in both in vitro a

238 rations were significantly lower in the lean insulin-sensitive than in the lean insulin-resistant men

239 nsulin-sensitive than SC adipocytes and more insulin-sensitive than male adipocytes from either depot

240 ales, intra-abdominal PG adipocytes are more insulin-sensitive than SC adipocytes and more insulin-se

241 ransgenic mice are more glucose-tolerant and insulin-sensitive than wild type mice.

242 disrupt the rhythmic internal environment of insulin sensitive tissue, thereby predisposing the anima

243 ears, it has been established that VSM is an insulin-sensitive tissue like skeletal muscle and adipoc

244 e yet concerning the localization of PDK1 in insulin-sensitive tissue.

245 are e, f, g, diabetes-associated protein in insulin-sensitive tissues (DAPIT), and the 6.8-kDa prote

246 ities of intracellular calcium metabolism in insulin-sensitive tissues (liver, skeletal muscle, and a

247 which enhances glucose utilization among the insulin-sensitive tissues (skeletal muscle, liver, heart

248 inistration regulated key metabolic genes in insulin-sensitive tissues and conferred a strong protect

249 2 influences insulin-mediated GU in multiple insulin-sensitive tissues and may explain, at least in p

250 e body weight through targeting pancreas and insulin-sensitive tissues and organs via site-specific m

251 regulators of inflammation and autophagy in insulin-sensitive tissues and postulate sEH as a druggab

252 etabolic effects of an inflammatory state in insulin-sensitive tissues appear essential for permanent

253 cial for energy homeostasis control, and key insulin-sensitive tissues are still unknown.

254 ggest that the delivery of insulin itself to insulin-sensitive tissues could be a mechanism of insuli

255 lin signaling cascade that modulates mTOR in insulin-sensitive tissues has been a major focus of inve

256 emonstrated that decreased lipid delivery to insulin-sensitive tissues improves insulin sensitivity a

257 esis that the deposition of triglycerides in insulin-sensitive tissues other than adipocytes causes i

258 In addition to p85alpha and p85beta, insulin-sensitive tissues such as fat, muscle, and liver

259 by pp185 tyrosine phosphorylation status in insulin-sensitive tissues using the Western blotting met

260 n regulates CREB transcriptional activity in insulin-sensitive tissues via the Raf --> MEK pathway an

261 40-75% in TG compared with wild-type mice in insulin-sensitive tissues with no change in GLUT4 conten

262 f, g, DAPIT (diabetes-associated protein in insulin-sensitive tissues), and 6.8PL (6.8-kDa proteolip

263 LAR, a transmembrane PTPase expressed in insulin-sensitive tissues, acts as a negative regulator

264 d 19,20-epoxydocosapentaenoic (19,20-EDP) in insulin-sensitive tissues, especially liver, as determin

265 feedback loop including islet beta cells and insulin-sensitive tissues, in which tissue sensitivity t

266 GLUT4, the glucose transporter present in insulin-sensitive tissues, resides in intracellular vesi

267 nd type II isozymes of hexokinase coexist in insulin-sensitive tissues, such as cardiac and skeletal

268 nover is regulated differently than in other insulin-sensitive tissues, such as skeletal muscle.

269 nism/antagonism influences insulin action in insulin-sensitive tissues.

270 mus, innate and adaptive immune systems, and insulin-sensitive tissues.

271 ty acids (LCFAs) and is expressed in several insulin-sensitive tissues.

272 p110beta catalytic subunits was observed in insulin-sensitive tissues.

273 viously less intensively perfused regions of insulin-sensitive tissues.

274 both the expression and activity of PTP1B in insulin-sensitive tissues.

275 glycemia and so-called "glucose toxicity" in insulin-sensitive tissues.

276 attern of expression of the MEF2 isoforms in insulin-sensitive tissues.

277 on in HepG2 and 3T3-L1 cell lines, models of insulin-sensitive tissues.

278 PTG was expressed predominantly in insulin-sensitive tissues.

279 ating free fatty acids and thus causes IR in insulin-sensitive tissues.

280 the induction of LCN2 varied among different insulin-sensitive tissues.

281 e for this methyltransferase in signaling in insulin-sensitive tissues.

282 and 3) insulin signal transduction (IST) in insulin-sensitive tissues.

283 kin-6 in the hypothalamus and key peripheral insulin-sensitive tissues.

284 ites contributes to a better redox status in insulin-sensitive tissues.

285 tion and metabolic processes in a variety of insulin-sensitive tissues; however, its role in regulati

286 nes Scd-1 and Fas is regulated partly by the insulin-sensitive transcription factor SREBP-1c and live

287 These novel data indicate that the insulin-sensitive transporter GLUT4 transports DHA in bo

288 AKO/cTg mice were highly insulin sensitive under hyperinsulinemic-euglycemic clam

289 se GU of insulin-stimulated muscles from the insulin-sensitive versus insulin-resistant group.

290 e consistent with the notion that a distinct insulin-sensitive vesicular cargo compartment forms earl

291 The differentiated cells possess a large insulin-sensitive vesicular compartment with negligible

292 They also express components of the insulin-sensitive vesicular transport machinery, namely,

293 Sixteen lean insulin-sensitive volunteers received intravenous fat (i

294 iet, the Pten-deleted mice remained markedly insulin sensitive, which correlated with massive subcuta

295 SCID mice were also more insulin sensitive with increased muscle glucose metaboli

296 ination, bilirubin-treated DIO mice remained insulin sensitive with lower leptin and higher adiponect

297 We have recently shown this cell to be insulin sensitive with respect to glucose uptake, with k

298 state plasma glucose concentrations than did insulin-sensitive women (10.8 +/- 0.5 compared with 4.1

299 mitochondrial physiology compared with lean, insulin-sensitive women (BMI 23 kg/m(2)).

300 icantly greater in insulin-resistant than in insulin-sensitive women (P < 0.001).