ライフサイエンスコーパス: integral

1 d that reproduces experimental Kirkwood-Buff integrals.

2 ure of the cytosolic portion of the membrane-integral adenylyl cyclase Cya from Mycobacterium intrace

3 The correlation between time integral and approximation improved with increasing time

4 ) functions are regulated by a complement of integral and peripheral proteins that associate with the

5 Nucleotidyl cyclases, including membrane-integral and soluble adenylyl and guanylyl cyclases, are

6 geal tissue differentiation (identity) as an integral and specific part of the pathophysiology of EoE

7 mall aircraft by a novel Gauss' Theorem flux integral approach.

8 motion, and capture of surveillance data are integral aspects of the eSHC.

9 Since MMPs are integral at every stage of metastasis, MMP roles in canc

10 carrying out the Msr activity, and MsrQ, an integral b-type heme membrane-spanning protein, which ac

11 n-protein and protein-ligand interactions of integral bitopic membrane proteins with a single membran

12 an end-expiratory occlusion on velocity-time integral can predict fluid responsiveness with similar r

13 served during both occlusions, velocity-time integral changed by 23% +/- 9% in responders and by 8% +

14 exploring the structure and function of the integral chromophores.

15 se cells in Arabidopsis thaliana, AUG8 is an integral component [2].

16 ently, we demonstrate Nkx2.2 functions as an integral component of a modular regulatory program to co

17 rvations suggest that IRE1 attenuation is an integral component of anabolic programmes regulated by A

18 that Nav1.2-driven spiking of pre-OLs is an integral component of axon-glial communication and is re

19 tatory V2a interneurons in particular are an integral component of central pattern generators that co

20 hlight that ethylene release is an early and integral component of in vivo lipid peroxidation with im

21 rd has hopped on the long road to syntax, an integral component of language.

22 ential drugs in the discovery pipeline is an integral component of most programs.

23 The extracellular microenvironment is an integral component of normal and diseased tissues that i

24 er conditions in which GODZ processing is an integral component of pathogenesis.

25 patitis B immune globulin (HBIG) has been an integral component of prophylaxis against hepatitis B vi

26 ce of cellular debris has been considered an integral component of resolving inflammation and restori

27 One such factor, Spt4/5, becomes an integral component of the elongation complex, making dir

28 ructure of HTNV envelope glycoprotein Gn, an integral component of the Gn-Gc glycoprotein spike compl

29 n 1, which includes multiple isoforms, is an integral component of the LINC complex, critical for nuc

30 Consistently, we find that Mff is an integral component of the MARCH5/p97/Npl4 complex, which

31 trophic cyanobacterium, Trichodesmium, is an integral component of the marine nitrogen cycle and cont

32 -binding eIF4E-homologous protein 4EHP is an integral component of the miRNA-mediated silencing machi

33 of ocean primary productivity, making it an integral component of the ocean's biogeochemical cycles.

34 Pectin, an integral component of the plant cell wall, is a recalcit

35 tion of cell wall-reinforcing papillae is an integral component of the plant immune response.

36 ocon-associated protein (TRAP) complex is an integral component of the translocon, assisting the Sec6

37 indings demonstrate a role for Galphas as an integral component of the ubiquitin-dependent endosomal

38 ) regulates the activity of beta-catenin, an integral component of Wnt signaling.

39 modifications, such as DNA methylation, are integral components for timing endogenous biological rhy

40 trate that multiple isoforms of Nesprin1 are integral components of ciliary rootlets of multiciliated

41 harbour a high functional potential and are integral components of functional gene dynamics in aquat

42 ells located near the epithelial barrier are integral components of local inflammatory and innate imm

43 Pericytes and smooth muscle cells are integral components of the brain microvasculature.

44 rin light chain isoforms, CLCa and CLCb, are integral components of the endocytic machinery whose dif

45 g with lignocellulose degrading enzymes, are integral components of the secretome of Pleurotus ostrea

46 ase ATM and the transcription factor p53 are integral components required for induction of IR-induced

47 We conclude that Kaps constitute integral constituents of the NPC whose barrier, transpor

48 The signaling network comprising the integral constituents of the signature pathways involved

49 absolute values of changes in velocity-time integral during both occlusions with a similar reliabili

50 nents, and (3) implantable blood pump or its integral electric driveline.

51 are derived as self-consistent solutions of integral equations.

52 Phosphatidic acid (PA) and the conserved integral ER membrane protein Scs2p regulate localization

53 ur parallel linear polarization channels and integral field spectroscopy with numerous slit dispersiv

54 1 cells produce natural Abs which provide an integral first line of defense against pathogens while a

55 logies and additive manufacturing, have been integral for advancing the field of tissue engineering.

56 modifier (SUMO), has also been recognised as integral for efficient repair.

57 Autophagy is a cellular degradation process integral for promoting cellular adaptation during metabo

58 , impedance drop [Delta-Imp], CF, force-time integral [FTI], and ablation index [AI]) and contiguity

59 olution is given in terms of the exponential integral function with relativistic co-ordinate transfor

60 The tooth root is an integral, functionally important part of our dentition.

61 FXR1 associates with intercalated discs, and integral gap junction proteins Cx43 (connexin 43), Cx45

62 l hierarchy that can then be viewed using an integral graphical viewer or animated through a high-lev

63 rmed and an increase of aortic velocity time integral greater than or equal to 10% defined fluid resp

64 Th17 and regulatory T (Treg) cells are integral in maintaining immune homeostasis and Th17-Treg

65 Point-of-care (POC) diagnostic devices are integral in the health care system and particularly for

66 y do not take into account), are nonetheless integral in the immune system.

67 Integral in the regulation and initiation of death recep

68 what patterns of nearest-neighbour transfer integrals in the two-dimensional (2D) high-mobility plan

69 nhancer of ADSC adipogenesis and suggests an integral interaction between the human skin microbiome a

70 Nearly simultaneously, the Fermi and INTEGRAL (INTErnational Gamma-Ray Astrophysics Laborator

71 nd-expiratory occlusion change velocity-time integral is greater than or equal to 13% in total, fluid

72 aturation (Ccm) is carried out by a membrane-integral machinery composed of nine proteins (CcmA to I)

73 motifs and site topology were identified for integral membrane and soluble proteins, indicating poten

74 allosterically modulate the interactions of integral membrane and soluble proteins.

75 ciliary trafficking of structurally diverse integral membrane cargo, including multiple reported and

76 acylglycerol acyltransferase 1 (DGAT1) is an integral membrane enzyme catalyzing the final and commit

77 ght to nucleate from vesicles containing the integral membrane protein Atg9 (autophagy-related 9), CO

78 ne nucleotide transhydrogenase (PntAB) is an integral membrane protein complex participating in the r

79 It is also believed that CPR is an integral membrane protein exclusively.

80 We found that KOC1 is an integral membrane protein facing the cytosol and stably

81 Integral membrane protein function can be modulated by t

82 e absence of NADPH and will transition to an integral membrane protein in the presence of stoichiomet

83 the soluble protein serum albumin and to the integral membrane protein NapA shows that soluble protei

84 The hpnN gene of B. multivorans encodes an integral membrane protein of the HpnN family of transpor

85 anding of the regulation and function of the integral membrane protein PEMT was improved when the enz

86 n meso crystallization to a broader range of integral membrane protein targets, the cubicon method sh

87 ustly predicted effects on expression of the integral membrane protein TatC for a set of 140 sequence

88 The endoplasmic reticulum (ER) integral membrane protein VAP is a common component of M

89 opy to refine the structure of an oligomeric integral membrane protein, Anabaena sensory rhodopsin (A

90 uires its operon partner ToxS, a periplasmic integral membrane protein, for full activity.

91 d raft-like domains, whereas M2, although an integral membrane protein, is not raft associated.

92 dentify the interfacial sites of a trimeric, integral membrane protein, OmpF, solubilised in micelles

93 Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) contributes

94 D of the succinate dehydrogenase complex, an integral membrane protein.

95 n physiological ligand, podoplanin, being an integral membrane protein.

96 sites of hydrophobic ligand incorporation in integral membrane proteins (IMPs), where poor aqueous so

97 Integral membrane proteins (MPs) are key engineering tar

98 growing interest in studying and engineering integral membrane proteins (MPs) that play key roles in

99 Claudins are a family of integral membrane proteins and are components of tight j

100 with cholesterol, detergents, peptides, and integral membrane proteins and formation of lipid rafts.

101 Integral membrane proteins are studied with a number of

102 al method for the rational overexpression of integral membrane proteins based on computationally simu

103 We also show that quality control of integral membrane proteins by ribosome-associated comple

104 ongation of the N-terminal sequence of these integral membrane proteins can divert the nascent protei

105 The heterologous overexpression of integral membrane proteins in Escherichia coli often yie

106 The abundance of integral membrane proteins in the plasma membrane is det

107 oss the cytoplasmic membrane or insertion of integral membrane proteins into the phospholipid bilayer

108 The copper transporter (Ctr) family of integral membrane proteins is ubiquitously found in euka

109 The integral membrane proteins LMBD1 and ABCD4 are required

110 m 18 different proteins, including the three integral membrane proteins Mps3, Ndc1, and Mps2.

111 Integral membrane proteins of the divalent anion/Na(+) s

112 eurotransmitter:sodium symporters (NSSs) are integral membrane proteins responsible for the sodium-de

113 Ion pumps are integral membrane proteins responsible for transporting

114 ers (VITs) are a poorly understood family of integral membrane proteins that can function in iron hom

115 ce-nodulation-cell division efflux pumps are integral membrane proteins that catalyze the export of s

116 Adiponectin receptors (ADIPORs) are integral membrane proteins that control glucose and lipi

117 ble protein trafficking, processes targeting integral membrane proteins to cilia are poorly understoo

118 Targeting of most integral membrane proteins to the endoplasmic reticulum

119 Aquaporins (AQPs) are integral membrane proteins whose function is to regulate

120 Phosphoglycosyl transferases (PGTs) are integral membrane proteins with diverse architectures th

121 he abundance, distribution and repertoire of integral membrane proteins within their immense, archite

122 tals and high-resolution X-ray structures of integral membrane proteins.

123 ns, like hemagglutinin (HA), NA, and M2, are integral membrane proteins.

124 lity of the method is demonstrated with five integral membrane proteins: the beta2-adrenergic G prote

125 The phagophore is largely devoid of integral membrane proteins; thus, its shape and size are

126 n extracellular SusD-like lipoprotein and an integral membrane SusC-like TonB-dependent transporter.

127 ion into two parts: the cytosolic V1 and the integral membrane V0 subcomplex.

128 Phosphatidylserine binds to an integral-membrane N-terminal domain (NTD); however, how

129 over both iterative and aortic velocity-time integral methods.

130 functionality for two potential applications-integral micro-scale imaging devices and light field dis

131 f 986 proteins into soluble, peripheral, and integral mitochondrial membrane proteins, and the assign

132 ntal NMR parameters and rationalized by path integral molecular dynamics simulations that involve nuc

133 nspiratory occlusion decreased velocity-time integral more in responders than in nonresponders (12% +

134 expiratory occlusion increased velocity-time integral more in responders than in nonresponders to flu

135 absolute values of changes in velocity-time integral observed during both occlusions, velocity-time

136 eviations of the approximation from the time integral of median +5% (range, -9% to +17%) for kidneys,

137 role of the fundamental number-of-particles integral of motion of the nonlinear Schrodinger equation

138 The exchange integral of one DBS with the electron confined in the NC

139 ere triggered by a threshold in the temporal integral of the bar error angle rather than its absolute

140 nd-expiratory occlusion on the velocity-time integral of the left ventricular outflow tract.

141 ion and were triggered by a threshold in the integral of velocity over time.

142 mbined with longer transient decay stabilize integrals of diastolic Ca and NCX current signals.

143 This is attested to by band integrals of the pump-probe spectra where photoinduced b

144 large fluctuation of intermolecular transfer integrals, often referred to as off-diagonal dynamic dis

145 evaluated for each fit function how well the integral over time was represented by an approximation c

146 me (P=0.002), pulmonary artery velocity time integral (P=0.006), and RV maximum +dP/dt (P<0.001), and

147 alized health monitoring (PHM), which is its integral part and may provide valuable information's on

148 housands of years and microorganisms play an integral part in this process as they not only drive fer

149 These findings show that MutLbeta is an integral part of a new regulatory step of meiotic recomb

150 acrocyclic restraints, and they also form an integral part of a small apolar core.

151 Nursing is an integral part of all healthcare services, and has the po

152 contain the spread of these pathogens and an integral part of antimicrobial stewardship.

153 3 germline mutation carriers and may form an integral part of baseline clinical risk management in th

154 lly active natriuretic peptides (NPs) are an integral part of cardiac homeostasis as they help to mai

155 As an integral part of CeD management, multiple professional o

156 data suggest that an ID consult should be an integral part of clinical care of patients with cryptoco

157 onservation indicates that this domain is an integral part of cyclase machinery across protein famili

158 when genome sequencing becomes a routine and integral part of disease diagnosis and management.

159 Cyanobacteria are an integral part of Earth's biogeochemical cycles and a pro

160 including metabolic tracing studies, are an integral part of elucidating the role of ammonia in thes

161 ct in tissue-specific esophageal genes is an integral part of EoE pathogenesis.

162 their biologically inert ground state is an integral part of GPCR signaling.

163 Information sharing is an integral part of human interaction that serves to build

164 The microbiome is an integral part of human physiology; recent studies show t

165 Structure-based drug design is an integral part of modern day drug discovery and requires

166 Nonreciprocal circuit elements form an integral part of modern measurement and communication sy

167 effective treatment of diabetes should be an integral part of multidisciplinary management of schizop

168 ete itch information and NMBR neurons are an integral part of neural circuits for itch in the spinal

169 improvement (QI) initiatives have become an integral part of patient-centered care.

170 The cytoskeleton is an integral part of skeletal muscle structure, and reorgani

171 ch aimed at the implementation of MOFs as an integral part of solid-state microelectronics.

172 rol the size of the electronic bandgap is an integral part of solid-state technology.

173 ing/middening and water management formed an integral part of the agricultural strategy from the seve

174 ur study reveals that APE1 acetylation is an integral part of the BER pathway for maintaining genomic

175 for BTX actions, probably functioning as an integral part of the BTX receptor.

176 This conformational change is an integral part of the catalytic cycle.

177 d HjLPMO9A revealed that the linker forms an integral part of the catalytic domain structure, coverin

178 Recent studies reveal that an integral part of the cellular management of misfolded pr

179 These results support that 6mA is an integral part of the chromatin landscape shaped by adeno

180 ) properties of new chemical entities are an integral part of the current industrial drug discovery p

181 siology of the plant as the template, and an integral part of the devices.

182 higher-order chromatin regulation may be an integral part of the differentiation capacity that defin

183 nin(s) and alpha-dystroglycan (alpha-DG), an integral part of the dystrophin-glycoprotein complex.

184 e Molecular diagnostic testing has become an integral part of the evaluation of patients with metasta

185 Starting out as an integral part of the fan-shaped body primordium, the pos

186 uni the periplasmic binding protein CeuE, an integral part of the Fe(III) transport system, has adapt

187 Proprioception is an integral part of the feedback circuit that is essential

188 Journals are an integral part of the foundation of scientific endeavor,

189 Therefore, neuroestradiol is an integral part of the hypothalamic engagement in response

190 BACKGROUND & AIMS: Endoscopy is an integral part of the investigation and management of gas

191 Spirituality is an integral part of the life narrative of the patient befor

192 enshaw cells are not directly required as an integral part of the locomotor coordination machinery, t

193 sources show that lectures on ethics were an integral part of the medical curriculum in Germany betwe

194 Neuroinflammation is an integral part of the neurodegeneration process inherent

195 Exercise is an integral part of the rehabilitation of patients sufferin

196 d by environmental stress and can also be an integral part of the toxicity response in our study spec

197 We demonstrate that Notch signaling is an integral part of the Wnt and Fgf signaling feedback loop

198 scale is not simply a solvent, but rather an integral part of their structure and potential functions

199 Targeting CK1epsilon should become an integral part of therapeutic strategies targeting transl

200 Programmed cell death (apoptosis) is an integral part of tissue homeostasis in complex organisms

201 As a result, the eBioKit has formed an integral part of training and research performed by a wi

202 Purpose Delayed intensification (DI) is an integral part of treatment of childhood acute lymphoblas

203 r localization study indicated that it is an integral plasma membrane protein.

204 One integral player is IFN regulatory factor (IRF)-8, which

205 ic translocators that form a plasma membrane-integral pore, and the hydrophilic 'tip complex' translo

206 e investigated a novel link between membrane-integral PRKs and the actin cytoskeleton, mediated throu

207 The spleen plays an integral protective role against encapsulated bacterial

208 Lamina-associated polypeptide 1 (LAP1) is an integral protein of the inner nuclear membrane that has

209 specific role of claudin-3, a tight junction integral protein, in inhibiting colon cancer progression

210 n organisation by segregating peripheral and integral proteins into domains of different rigidity.

211 x mechanisms by which tubulin interacts with integral proteins of the mitochondrial outer membrane an

212 Our data suggest an integral role for Renshaw cell signaling in shaping the

213 These findings support an integral role for satellite cells in the aetiology of le

214 Our data support an integral role for the LC in modulating the severity of b

215 usly reported that the RRV VP4 gene plays an integral role in activating the immune system and induct

216 Mitochondria play an integral role in cell death, autophagy, immunity, and in

217 S proteasome core particle (20S CP) plays an integral role in cellular homeostasis by degrading prote

218 lts indicate that queen presence can play an integral role in colony behaviour, survivorship and thei

219 Multimodality imaging techniques play an integral role in determining the underlying etiology and

220 target interaction (DTI) prediction plays an integral role in drug repositioning: the discovery of ne

221 TNF plays an integral role in inflammatory bowel disease (IBD), as ev

222 uggesting that white adipose tissue plays an integral role in mediating the metabolic effects of EPO.

223 neurons suggests that Renshaw cells have an integral role in movement, a role that is yet to be eluc

224 also influences motor outcome pointing to an integral role in online control of rhythmic behavior.SIG

225 well characterized, it continues to play an integral role in peripheral T cells, in which a unique m

226 KDM5B, which demethylates H3K4me3, plays an integral role in regulating RNAPII occupancy, transcript

227 Water storage is thought to play an integral role in the maintenance of whole-plant water ba

228 Foveal Muller cells may play an integral role in the transmission of mechanical forces t

229 logy modelling we predicted and confirmed an integral role of arginine(172), located in the 2nd extra

230 e first in vitro and in vivo evidence of the integral role of previously unrecognized crosstalk betwe

231 pothesized that MAFB, MMP-2, and MMP-14 have integral roles in carpal/tarsal and epiphyseal bone deve

232 n aqueous solution of NaOH (0.75% w/v) using integral samples for extraction resulted in the highest

233 Bacteria use membrane-integral sensor histidine kinases (HK) to perceive stimu

234 and gestural components are two distinct yet integral sides of communication, which need to be studie

235 D79b proteins associate with Ig receptors as integral signaling components of the B cell Ag receptor

236 on of the outer mitochondrial membrane is an integral step in apoptosis.

237 The BRD, PHD, and HAT domains form an integral structural unit to which the RING and ZZ domain

238 ila larvae or C. elegans worms has become an integral subject of biological research.

239 h at the ends of linear chromosomes using an integral telomerase RNA (TER) and telomerase reverse tra

240 l how flexibility in human brain networks is integral to achieving successful reasoning performance a

241 agonists of G protein-coupled receptors are integral to analysis of receptor function and to support

242 Performance measurement is integral to any PHM strategy.

243 They are integral to brain and spinal-cord physiology and perform

244 Heterochromatin is integral to cell identity maintenance by impeding the ac

245 t interactions between workers and brood are integral to colonies survival.

246 wearable computing is widely expected to be integral to consumer electronics and beyond.

247 luable resource for identifying new proteins integral to corpus callosum development that will provid

248 ses that dictate the fate of nanomedicine is integral to developing more effective individualized pla

249 indicates that nuclear receptor signaling is integral to dynamic changes in the cardiac mitochondrial

250 that GPR88 expression within the striatum is integral to efficient action-selection during foraging.S

251 sign safety to stimuli in the environment is integral to everyday functioning.

252 nd objects surround us, and touching them is integral to everyday life.

253 ed hemodynamic responses over neural regions integral to fluent speech production including inferior

254 environmental assessments, or durable goods integral to home environmental interventions.

255 Cellular protein interaction networks are integral to host defence and immune signalling pathways,

256 Oxidative stress and inflammation are integral to hypertension-induced renal injury.

257 Cells in auditory cortex believed to be integral to ILD processing (excitatory from one ear, inh

258 Mechanical forces are integral to many biological processes; however, current

259 Multidimensional data are integral to many community-ecological studies and come i

260 tics programs, web servers and databases are integral to modern science, but previous studies have sh

261 pite decades of evidence that astrocytes are integral to neural circuit function, it seems as though

262 As the ventral hippocampus is integral to neurocircuitry that mediates emotional behav

263 ization by anisotropic substrate features-is integral to numerous physiological processes; however th

264 elative changes to the MII transcriptome are integral to oocyte quality.

265 sociation may be attributable to a mechanism integral to other factors, such as parental age and moth

266 ies uncover a p53-Ptpn14-Yap pathway that is integral to p53-mediated tumor suppression.

267 Metabolism is integral to pathogenicity.

268 ygen (O2)-mediated Cu(I)-->Cu(II) redox step integral to SCR.

269 the transient interfacial area, a parameter integral to short processing times for productivity stre

270 driving force in disease progression and is integral to spin function in the adult nervous system.

271 Correctly identifying friends and foes is integral to successful group living.

272 Data were thematically analysed using steps integral to the 'Framework' approach to analysis, includ

273 ntification and characterization of proteins integral to the Arabidopsis (Arabidopsis thaliana) seed

274 These genes are integral to the baculovirus life cycle and may be good f

275 pulation of angiotensin-sensitive neurons is integral to the coordination of stress responses.

276 indicate that retrotransposon activation is integral to the developmental program.

277 led somatostatin (sst) receptor agonists are integral to the diagnosis of gastroenteropancreatic neur

278 However, such transient precursors may be integral to the formation of more stable phases.

279 ily-independent, actin stabilization that is integral to the formation of one RhoGEF array.

280 IL-1beta release is integral to the innate immune system.

281 While ensuring that the protein remains integral to the membrane, such methods can be used to id

282 These regulatory mechanisms are integral to the myriad PTP-mediated biochemical events a

283 naling, suggesting that these sites could be integral to the network organization and coordination of

284 DNA-PKcs, which is integral to the non-homologous end joining pathway, thus

285 ing Lewis acid formed, BEt3, was found to be integral to the observed catalysis.

286 vidence that suggests sexual transmission is integral to the pathogenesis of bacterial vaginosis, whi

287 The renal vasculature is integral to the physiologic function of the kidneys in r

288 SEC63, these genes encode proteins that are integral to the protein biogenesis pathway in the endopl

289 The claudin family of proteins is integral to the tight junction (TJ), the apical cell-cel

290 a nucleus of the dorsal midline thalamus, is integral to this behavioral competition.

291 that MADS-RIN protein-regulation of sHSPs is integral to tomato fruit ripening.

292 Integral transmembrane proteins assume a beta-barrel str

293 We found that the integral transmembrane proteins SUN1/UNC84A and SUN2/UNC

294 spectral bands, hierarchical clustering and integral values of the component bands by curve fitting,

295 Using linear regression analysis of spectral integral values, 4 counterfeited samples from Russia and

296 e consists of soluble V1-ATPase and membrane-integral Vo proton channel sectors.

297 ratio of late/early ejection-phase MWS time integrals was computed as an index of late systolic myoc

298 eviations of the approximation from the time integral were calculated for time points tl of 24, 48, 7

299 ysis-derived cardiac index and velocity-time integral were measured during the last 5 seconds of 15-s

300 ry occlusion-induced change in velocity-time integral with an area under the receiver operating chara