ライフサイエンスコーパス: integrin alpha1beta1

1 PC12 cells to peptide III-7 was mediated by integrin alpha1beta1.

2 ) truncated protomer) that selectively binds integrin alpha1beta1.

3 duced pCav-1 levels only in cells expressing integrin alpha1beta1.

4 pe IV collagen, by promoting the function of integrin alpha1beta1.

5 pCav-1 is a new substrate of TCPTP and that integrin alpha1beta1 acts as a negative regulator of Cav

6 g growth factor (TGF)-beta1 and the other by integrin alpha1beta1, affect Alport glomerular pathogene

7 How modulating integrin alpha1beta1 affinity alters collagen homeostasi

8 ibodies, we determined that adhesion through integrins alpha1beta1, alpha2beta1, alphavbeta3, and alp

9 r processes through its interaction with the integrins, alpha1beta1, alpha2beta1, alpha10beta1, and a

10 on the back skin of control and mice lacking integrin alpha1beta1 and alpha2beta1.

11 , these findings uncover a crosstalk between integrin alpha1beta1 and TbetaRII that is essential for

12 These data suggest that integrin alpha1beta1 and TGF-beta1 may provide useful ta

13 If both integrin alpha1beta1 and TGF-beta1 pathways are function

14 We now report that the integrins alpha1beta1 and alpha2beta1 are receptors for

15 The collagen-binding integrins alpha1beta1 and alpha2beta1 have been shown to

16 In conclusion, the loss of integrins alpha1beta1 and alpha2beta1 in mice results in

17 Mesangial cells and podocytes express integrins alpha1beta1 and alpha2beta1, which are the two

18 alpha1 and alpha2, which resulted in loss of integrins alpha1beta1 and alpha2beta1.

19 Instead, inhibiting integrins alpha1beta1 and alpha5beta1 curtails both gale

20 IV)NC1 domain of type-IV collagen could bind integrins alpha1beta1 and alphavbeta3 expressed on melan

21 asts lack receptors and distal cells express integrins alpha1beta1 and alphaVbeta3, enabling virion a

22 gated the role of the major collagen-binding integrins, alpha1beta1 and alpha2beta1, in several in vi

23 te (int)) DCs expresses the collagen-binding integrin, alpha1beta1, and the E-cadherin-binding integr

24 Thus, we have identified integrin alpha1beta1 as a modulator of glomerulosclerosi

25 ion is significantly higher in cells lacking integrin alpha1beta1 at base line and following oxidativ

26 Integrin alpha1beta1 binding to collagen IV, which is me

27 Cav-1 interacts with integrins, and integrin alpha1beta1 binds/activates T cell protein-tyro

28 ncogenic Kras, suggesting that both Kras and integrin alpha1beta1 cooperate to drive the growth of no

29 PARgamma axis plays a key role in regulating integrin alpha1beta1-dependent Cav-1 expression and cons

30 Integrin alpha1beta1-dependent endothelial cell prolifer

31 for biomechanical insult in the induction of integrin alpha1beta1-dependent Rac1-mediated mesangial c

32 Thus, our study demonstrates that integrin alpha1beta1-EGFR cross talk is a key step in ne

33 is report demonstrates a direct link between integrin alpha1beta1 function in retinal pigment epithel

34 The collagen IV binding receptor integrin alpha1beta1 has been shown to regulate lung can

35 his could explain the protective function of integrin alpha1beta1 in oxidative stress-mediated damage

36 Integrin alpha1beta1 is a collagen receptor abundantly e

37 Integrin alpha1beta1 is a collagen receptor that down-re

38 Integrin alpha1beta1 is a collagen-binding receptor expr

39 pand the CPP-I receptor family, showing that integrin alpha1beta1 is also a receptor for CPP-I.

40 av-1 (pCav-1) is a substrate of TCPTP and if integrin alpha1beta1 is essential for promoting TCPTP-me

41 Because integrin alpha1beta1 is expressed in many cell types thi

42 Integrin alpha1beta1 localizes to the basal aspect of re

43 h factor receptor signaling, participates in integrin alpha1beta1-mediated EGFR activation.

44 In addition, we showed a novel pathway where integrin alpha1beta1 modulates ROS production, which in

45 Thus, integrin alpha1beta1 negatively regulates EGFR activatio

46 Integrin alpha1beta1 negatively regulates the generation

47 ression is dependent on the collagen-binding integrin alpha1beta1 on VSMCs.

48 highly increased by the addition of purified integrin alpha1beta1 or an integrin alpha1 cytoplasmic p

49 Integrin alpha1beta1 protects from glomerular injury by

50 Integrin alpha1beta1, the major collagen type IV recepto

51 how that adhesion by the collagen IV-binding integrin alpha1beta1 unexpectedly inhibited macrophage e

52 The integrin alpha1beta1 (very late antigen-1; CD49a/CD29) i

53 The collagen-binding receptor integrin alpha1beta1 was required for recruitment of TCP

54 rtex from Alport mice are immunopositive for integrin alpha1beta1, while only a small fraction of cir