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5 n macrophages and adipocytes mediated by the integrin alpha4 and its counter-receptor VCAM-1, respect
6 s study examined the role of leukocyte beta1 integrin (alpha4) and its endothelial ligand VCAM-1 in C
7 ytokine receptors, including integrin beta1, integrin alpha4, and CXC chemokine receptor 4 (CXCR4).
9 of neutrophils to mindin is blocked by anti-integrin alpha4, anti-integrin alpha(M), and anti-integr
11 ted with synthetic peptides that contain the integrin alpha4 binding site in fibronectin displayed ab
12 d T cell lines and clones expressed CD44 and integrin alpha4, but not L-selectin, and entered the CNS
13 surprisingly, Rh-alpha4beta7 did not impact integrin alpha4(+) cells, but decreased the frequencies
14 antibodies to MAdCAM-1, alpha4beta7, or the integrin alpha4 chain indicating that MAdCAM-1 in inflam
15 It was previously shown that mutations of integrin alpha4 chain sites, within putative EF-hand-typ
18 netic or pharmacological inactivation of the integrin alpha4 in mice resulted in elevated expression
20 vitro prevented the culture-induced loss of Integrin-alpha4 (ITGA4) expression as well as homing.
21 ether, these data suggest that CXCR3 and the integrin alpha4 mediate T cell recruitment to uninfected
22 n situ hybridization demonstrates that chick integrin alpha4 mRNA is expressed at high levels by migr
26 livary glands depended on chemokines and the integrin alpha4 Several chemokines were expressed in the
30 ers, we obtained a PCR fragment of the chick integrin alpha4 subunit that was subsequently used to cl
32 lpha9 subunit is structurally similar to the integrin alpha4 subunit, and alpha9beta1 and alpha4beta1
33 ublished beta-propeller folding model of the integrin alpha4 subunit, in which seven four-stranded be
34 nce of a blocking antibody against the mouse integrin alpha4 subunit, there was a profound abrogation
36 nce was truncated, replaced with that of the integrin alpha4, the integrin alpha2, or maintained inta
38 ized mice bearing a Y991A mutation in alpha4 integrin [alpha4(Y991A) mice], which blocks paxillin bin
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