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1 membrane pemphigoid and mAb GoH3 and BQ16 to integrin alpha6.
2 tes with the down-regulation of cell surface integrin alpha6.
3 we developed a platelet-specific knockout of integrin alpha6.
5 in luminal cells that express keratin 14 and integrin-alpha6, a phenotype that is usually expressed e
7 maintained on feeders or off feeders express integrin alpha6 and beta1, which may form a laminin-spec
9 e proband revealed negative staining for the integrin alpha6 and markedly reduced staining for the be
10 ch as plectin, collagen type XVII/BP180, and integrin alpha6 and ss4 chains, seen in conventional Lam
11 l TACE constructs demonstrated not only that integrins alpha6 and beta1 bind to TACE via the disinteg
13 pe IV collagen, type VII collagen, perlecan, integrin alpha6, and epithelial cell differentiation mar
17 gment E8, and dependence of this response on integrin alpha6 beta1 and at least one other long arm-bi
18 ls were a subset of the previously described integrin alpha6(+)CD34(+) bulge cell population, and 28.
21 s, suggesting that the formation of the CD82-integrin alpha6 complex reduces alpha6 integrin cell sur
24 xpected, CD82 physically associated with the integrin alpha6 in Du145-CD82 transfectant cells, sugges
25 ment significantly reduced the expression of integrin alpha6, integrin beta4, Fak, paxillin, Rac1/2/3
26 st therapeutic interventions to inhibit CCN1-integrin alpha6 interactions to sensitize gliomas to vir
27 Finally, the internalization of cell surface integrin alpha6 is significantly enhanced upon CD82 expr
29 sing cytokeratin15 (KRT15), CD200, CD34, and integrin, alpha6 (ITGA6) were quantitated via flow cytom
30 reshly isolated club cells express Sca-1 and integrin alpha6, markers commonly used to characterize l
31 )-dependent hepatocyte proliferation through integrin alpha6-mediated accumulation of reactive oxygen
32 a peptide within the extracellular domain of integrin alpha6 molecule, to which Abs in the sera from
36 he fluorescently labeled proteins identified integrin alpha6 precursor as a protein associated in a c
38 our results indicate that 1) CD82 attenuates integrin alpha6 signaling during a cellular morphogenic
40 Control sera did not bind to the full-length integrin alpha6 subunit nor any of the cloned fragments.
41 the binding of OP autoantibodies within the integrin alpha6 subunit, by cloning four overlapping fra
43 s; and 3) the accelerated internalization of integrin alpha6 upon CD82 expression correlates with the
45 t the lateral membrane, and beta-catenin and integrin alpha6 were located at the basolateral membrane
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