ライフサイエンスコーパス: integrin alphavbeta5

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1 rcinoma cell migration, an event mediated by integrin alphavbeta5.

2 adherence junctions through interacting with integrin alphavbeta5.

3 A neutralizing antibody against integrin alphaVbeta5, a known receptor for ANGPTL4, mimi

4 ated by alphavbeta3 and also activated other integrins, alphavbeta5, alpha5beta1, and alpha2beta1, in

5 angiocytes, CCN1 activated NF-kappaB through integrin alphavbeta5/alphavbeta3, leading to Jag1 expres

6 Blockade of integrin alphavbeta5/alphavbeta3, NF-kappaB, or NOTCH si

7 triggered by an interaction between gHgL and integrin alphavbeta5, alphavbeta6, or alphavbeta8.

8 cell matrix proteins, with the expression of integrin alphaVbeta5 and the integrin beta 1 subunit (wh

9 e coupling of focal adhesion kinase (FAK) to integrin alphavbeta5 and tyrosine phosphorylation of the

10 On attachment, integrins alphavbeta5 and alphavbeta3 localized to focal

11 Similarly, integrins alphavbeta5 and alphavbeta3 localized to focal

12 dination of membrane receptor syndecan-1 and integrin alphavbeta5, and triggered a signaling cascade

13 vity significantly, while a MAb specific for integrin alphavbeta5, as well as the MAb specific for al

14 dimensional structure of soluble recombinant integrin alphavbeta5 bound to human adenovirus types 2 a

15 We now report that integrin alphavbeta5 can also bind to gHgL and trigger f

16 havbeta3 to internalize vitronectin, whereas integrin alphavbeta5 constitutively internalizes vitrone

17 Furthermore, the closely related integrin, alphavbeta5, does not substitute for alphavbet

18 tral fibrin clot whereas the closely related integrin alphaVbeta5 failed to localize to these cells.

19 Another related alphav-containing integrin, alphavbeta5, fails to show similar responses,

20 s type 2 (AAV2), which lacks this RGD motif, integrin alphaVbeta5 has been identified as a coreceptor

21 Integrin alphavbeta5 has been identified as a regulator

22 cells overexpressing integrin alphaVbeta3 or integrin alphaVbeta5 in cocultures with primary pulmonar

23 oma cell invasion and metastasis mediated by integrin alphavbeta5 in part by promoting proteolytic cl

24 Integrin alphaVbeta5 interaction with CD98/xCT predomina

25 lens epithelial cells express members of the integrin alphaVbeta5-mediated phagocytosis pathway and t

26 protein initiates angiogenesis by binding to integrin alphavbeta5 on resting endothelium, thereby res

27 to cell lines that express the RGD-cognitive integrins alphaVbeta5 or alpha5beta1.

28 noma cells on a transcriptional level via an integrin alphavbeta5/phosphoinositide-3-kinase-dependent

29 both promote Ad internalization into cells, integrin alphavbeta5 selectively facilitates Ad-mediated

30 omotes a specific motility event mediated by integrin alphavbeta5, since cells transfected with the b

31 ibodies revealed that alphaV integrin(s) and integrin alphaVbeta5 specifically were critical for cell

32 ween endothelial cells via activation of the integrin alphavbeta5-Src signaling pathway.

33 oma cell invasion and metastasis mediated by integrin alphavbeta5 that is prevented by Src blockade.

34 The integrin alphavbeta5 vitronectin receptor is expressed o

35 12 (HAdV12) complexed with a soluble form of integrin alphavbeta5 was determined by cryo-electron mic

36 ociated with lung metastasis, while exosomal integrin alphavbeta5 was linked to liver metastasis.

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