ライフサイエンスコーパス: integrity

1 measured but poorly documented gauge of well integrity.

2 lms with altered architecture and structural integrity.

3 asal secretions of AR patients on epithelial integrity.

4 ut not on the axonal tracts or myelin sheath integrity.

5 cal roles patterning and maintaining barrier integrity.

6 tic shock by maintaining NK cell numbers and integrity.

7 oss of white matter connectivity and network integrity.

8 ion fidelity factor that compromises genomic integrity.

9 n dissociation without compromising filament integrity.

10 nvestigational therapies, and ensuring trial integrity.

11 creased the viability and bacterial membrane integrity.

12 y facile regeneration ability and structural integrity.

13 immune activation through maintaining genome integrity.

14 hment regardless of countries' institutional integrity.

15 on to promote DNA repair and preserve genome integrity.

16 but in all cases they lose their mechanical integrity.

17 tion, disk morphogenesis, and rod structural integrity.

18 improving hemodynamic parameters and vessel integrity.

19 t to mechanisms that maintain B-cell genomic integrity.

20 ain barrier model exemplifies tight-junction integrity.

21 us challenges to human health and scientific integrity.

22 maintain intracellular homeostasis and cell integrity.

23 es are not explained by compromised neuronal integrity.

24 opment but also a progressive loss of tissue integrity.

25 ts Pif1 function, DNA replication and genome integrity.

26 r endothelium with disrupted sub-endothelial integrity.

27 needed for spindle function and maintaining integrity.

28 sposons) silencing and maintenance of genome integrity.

29 elial regeneration and maintenance of tissue integrity.

30 al signaling that can lead to loss of tissue integrity.

31 serts into lipid bilayers and disrupts their integrity.

32 to severe defects in nuclear morphology and integrity.

33 ty is required to maintain adherens junction integrity.

34 t of the plasma membrane preceded loss of PM integrity.

35 ot seen for countries with low institutional integrity.

36 III controls the duration of plasma membrane integrity.

37 vin receptor-like kinase 5 to maintain early integrity.

38 nt for the maintenance of epithelial barrier integrity.

39 enhancing their birefringence and structural integrity.

40 behavior without losing their architectural integrity.

41 ally through the regulation of cell polarity integrity.

42 eaks (DSBs) is key for maintenance of genome integrity.

43 usceptible target cells and alter epithelial integrity.

44 t significant changes in complex assembly or integrity.

45 nsulin appeared to have preserved structural integrity.

46 ptic vesicles (SVs) and compromises synaptic integrity.

47 replication is essential to preserve genome integrity.

48 preserving framework porosity and structural integrity.

49 2), both of which are implicated in vascular integrity.

50 ses environmental stress to alter intestinal integrity.

51 intestine via regulation of apical junction integrity.

52 s critical to the nation's health and fiscal integrity.

53 well as impaired hippocampal microstructural integrity.

54 hile not compromising the fibres' mechanical integrity.

55 s a multifunctional RBP essential for genome integrity.

56 that immunosuppressives might affect airway integrity.

57 of impaired Ca(2+) homeostasis on myofibril integrity.

58 ue, and histological markers of dopaminergic integrity.

59 ow that caveolae are essential for notochord integrity.

60 opic, and postprocessing preserves geometric integrity.

61 ected, CD14 overexpression increased barrier integrity.

62 to support neuronal homeostasis and synaptic integrity.

63 the regulation of gene expression and genome integrity.

64 e chromosome segregation and preserve genome integrity.

65 hromatin to ensure the maintenance of genome integrity.

66 ry values (98%) without compromising maltene integrity.

67 do not obviously regulate epidermal barrier integrity.

68 and sustain large forces to maintain spindle integrity.

69 lum Ca(2+) spark frequency and disrupted JMC integrity.

70 reversible with full recovery of structural integrity after 1-2 weeks.

71 ted in repair mechanisms that restore tissue integrity after injury.

72 d remote organ injury and maintained tubular integrity after renal I/R injury.

73 that epigenetic aging and white matter tract integrity also share common genetic influences.

74 tions in cortical thickness and white matter integrity among children raised in deprived early enviro

75 gesting that activity feeds back to maintain integrity among motor neurons within a nucleus.

76 d during early development to protect genome integrity and aberrant transcription.

77 Alterations in the genome integrity and accumulation of mutations have been tightl

78 hrough their effect on enterococcal envelope integrity and antimicrobial resistance.

79 in microbial dormancy, maintenance of genome integrity and ATP homeostasis were robustly expressed.

80 tments, disrupts taste papilla and taste bud integrity and can eliminate responses from taste nerves

81 vivo imaging, we show that preserved muscle integrity and cell composition prior to the injury is ne

82 charides that are critical for cell envelope integrity and cell shape and also represent key antigeni

83 proinflammatory mediator, and it alters the integrity and cohesion of the blood-brain barrier in sev

84 lation, leading to a loss of microstructural integrity and consequently, reduced mechanical strength.

85 AZO layer and exhibited excellent mechanical integrity and electrical conductivity within a wide rang

86 with up to 6-month structural and mechanical integrity and excellent tissue compatibility represents

87 l, is pivotal to the maintenance of cellular integrity and for the protection of the cell from extern

88 sed that DBN protein abundance instructs the integrity and function of synapses.

89 onal downstream pathways that compromise the integrity and function of the RPE.

90 that, in turn, was linked to altered barrier integrity and function.

91 on a sampling strategy that preserves their integrity and in situ physiological state, e.g. viabilit

92 play important roles in maintaining telomere integrity and length.

93 NPY5 receptor antagonists restored vascular integrity and limited HSPC mobilization, demonstrating t

94 ing EAE/MS partially restores functional BBB integrity and limits immune cell infiltration into the C

95 d respiration without damaging mitochondrial integrity and liver functions.

96 The primary end point was endothelial integrity and muscular damage of the harvested vein.

97 which is not adequate to evaluate structural integrity and natural cracks.

98 k repair (SSBR) and is important for genetic integrity and normal neurological function.

99 unctions were examined by analyzing synaptic integrity and performing animal behavior on T1R3KO mice.

100 ce but also rescues the deficits in synaptic integrity and plasticity.

101 has been previously shown to affect vascular integrity and regenerative signaling, is here shown to r

102 mented in other systems and drive sensing of integrity and response by regeneration in other material

103 y required for characterizing the structural integrity and safety of infrastructure.

104 oth the privileged status of germline genome integrity and species-specific differences in genome mai

105 odulin binding contributes to SPB mechanical integrity and suggest that its removal may cause pole de

106 The retained structural integrity and the mechanism of water sorption were corro

107 bility of BAK to control peroxisome membrane integrity and the release of soluble peroxisomal matrix

108 with CL316,243 further reduced mitochondrial integrity and upregulated autophagy in the BAT of Gja1 (

109 Trace minerals (TM) play a role in skin integrity and wound healing.

110 tic density protein-95, a marker of synaptic integrity, and an increase in the ratio of insoluble Abe

111 Regional gray matter volume, white matter integrity, and functional connectivity during processing

112 trolled energy storage, long-term structural integrity, and high-rate cycling performance.

113 immune systems, epithelial renewal, barrier integrity, and mucosal vascularisation and innervation.

114 dered myofibrillogenesis and/or myofibrillar integrity, and the consequent myosin aggregation.

115 KZF1 result in deregulation of mitochondrial integrity, and this may play a pathogenic role in the de

116 lly to IreK and interfere with cell envelope integrity, antimicrobial resistance, and GIT colonizatio

117 Defects in maintaining genome integrity are a hallmark of cancer.

118 CNS angiogenesis and blood-brain barrier integrity are controlled by the canonical Wnt pathway.

119 ted PV+ network function and deficits in PNN integrity are implicated in a variety of psychiatric ill

120 is and during the loss of periodontal tissue integrity as a result of periodontal disease.

121 Ls in the maintenance of the mucosal barrier integrity, as well as how dysregulated IEL responses can

122 Membrane integrity assays confirm that the voltage delivered by t

123 To test for stress-induced changes in myelin integrity, aurophosphate (Black Gold) myelin staining wa

124 (a magnetic resonance spectroscopy neuronal integrity biomarker), and neuropsychological performance

125 neighboring cells that maintained epithelium integrity but did not absolutely require Caspase-1 or Ga

126 Alterations of GCS not only affect membrane integrity, but also closely correlate with stem cell plu

127 within cell walls, which provide structural integrity, but also spatially constrain cells, and must

128 of adult mice did not affect homeostatic BBB integrity, but resulted in BBB disruption and microvascu

129 untries with high and moderate institutional integrity, but this correlation was not seen for countri

130 by which Ca(2+) overload disrupts myofibril integrity by activating a Calcineurin-FoxO-MuRF1-proteos

131 Many of these peptides disrupt cell integrity by forming membrane-spanning pores that ultima

132 unctions and protected the cytotoxic lineage integrity by preventing TFH-lineage deviation.

133 e piRNA pathway and that it maintains genome integrity by silencing transposons.

134 aureus directly influences the skin barrier integrity by stimulating endogenous proteolytic activity

135 sure might be related to blood-brain barrier integrity by studying adult patients with normal brain p

136 Purpose To determine indexes of skeletal integrity by using computed tomographic (CT) trabecular

137 : (1) ethanol damages cell wall and membrane integrity, causing increased stresses, particularly reac

138 ct against these insults and maintain genome integrity, cells have evolved mechanisms to repair DNA l

139 e functions of cohesin are central to genome integrity, chromosome organization and transcription reg

140 We also found that the cell wall integrity (CWI) pathway contributes to the response to m

141 for protection against V8 protease-mediated integrity damage, and exogenous application of hBD2 was

142 We reveal that neuronal function and integrity decline rapidly with age, culminating in activ

143 , vacuolated cells maintain their structural integrity despite being under constant mechanical stress

144 nflammatory response and blood-brain barrier integrity dictate clinical outcomes.

145 importance, these alterations in centrosome integrity do not result from loss of mRNA export.

146 ription factor Pt-Ets4 is needed for cumulus integrity, dorsoventral patterning and for the activatio

147 BBB in the normal brain, their impact on BBB integrity during ischemia remains unclear.

148 How organs maintain and restore functional integrity during ordinary tissue turnover or following i

149 ditionally, Chlamydia maintain mitochondrial integrity during reactive oxygen species-induced stress

150 sible scenario requires the loss of membrane integrity (electroporation) and resulting depolarization

151 incorporates the possible effects on cuticle integrity, energetic metabolism and immune response.

152 peritoneal mesothelium disrupts mesothelial integrity, exposing the submesothelial collagen matrix o

153 the safety or security of the child's bodily integrity, family, or social structures, are known to be

154 oscopy revealed rapid restoration of bladder integrity following chitosan treatment, indicating that

155 tors for the maintenance of replication fork integrity following replication stress.

156 d survival and is a critical marker of islet integrity following rodent islet isolation.

157 racellular changes in endothelial cell layer integrity following the activation of the proteinase-act

158 el mechanism as to how WRN protects telomere integrity from damage and telomere erosion.

159 to uncouple their roles in maintaining axon integrity from their functions at AIS and nodes.

160 These findings suggest that maintaining Erk5 integrity has therapeutic potential for treating metabol

161 nical strains of S. aureus) inducing barrier integrity impairment and tight junction damage.

162 mage, and disrupted podocyte and endothelial integrity in 6 week-old Cd2ap-KO mice.

163 matic patients showed a significantly low TJ integrity in ALI cultures compared with HBECs from healt

164 cytokines, IL-4 and IL-13, decreased barrier integrity in ALI cultures of HBECs from control subjects

165 TH2 cells might decrease epithelial barrier integrity in AR, maintaining a leaky epithelial barrier.

166 paired maturation of intestinal immunity and integrity in boys with a risk of JIA.

167 fundamental to abnormalities in white matter integrity in early psychosis.

168 epigenetic age acceleration and white matter integrity in humans.

169 eplication fork stability contributes to DNA integrity in meiosis.

170 p demonstrated marginally better endothelial integrity in random samples (85% versus 88% versus 93% f

171 genetic data on the importance of B-subunit integrity in replisome function in vivo.

172 atter volume in MDD and reduced white matter integrity in several brain regions.

173 Measures of white matter integrity in the brain are also heritable and highly sen

174 , consistent with the increased white matter integrity in the corpus callosum connecting these region

175 in A2 (ANXA2) functions to maintain vascular integrity in the face of alveolar hypoxia.

176 x, hippocampus, and cerebellum; white matter integrity in the uncinate fasciculus, ventral frontal, a

177 Improved genomic integrity in these cells is linked to a substantial incr

178 further suggested defective apical junction integrity in these mice.

179 l surface, and decreased endothelial barrier integrity in vitro, therefore increasing permeability.

180 atients rapidly decreased epithelial barrier integrity in vitro.

181 ional anisotropy (FA), a measure of WM tract integrity, in a priori regions of interest: splenium of

182 nt AD are focusing on improving skin barrier integrity, including supplementing barrier function with

183 Vitamin A deficiency impairs epithelial integrity, increasing intestinal permeability.

184 Loss of epithelial integrity indicated by loss of the tight junction protei

185 Preservation of genome integrity is a conserved, essential function, yet genome

186 For individuals, integrity is an aspect of moral character and experience

187 However, subtelomere integrity is essential for T. brucei viability.

188 Since fly telomere integrity is guaranteed by a different mechanism, we use

189 Maintaining genome integrity is important for cells and damaged DNA trigger

190 he rapid S1P-induced increase in endothelial integrity is mediated by a S1PR1-Galphai-Cdc42 pathway.

191 initively establish that complete structural integrity is necessary to observe single-molecule fluore

192 estimations of gene expression when ribosome integrity is not compromised.

193 nce of this bond to the protein's structural integrity is unclear.

194 unction of RNAi in the maintenance of genome integrity is well known.

195 The observed alterations in the genome integrity maintenance may be particularly relevant in th

196 fundamental cellular processes, like genome integrity maintenance, characterize HUWE1-promoted XLID.

197 regulates essential processes such as genome integrity maintenance.

198 u vacancies to an extent that the structural integrity may not be maintained.

199 autonomously, bypassing the need for costly integrity monitoring and membrane replacement practices.

200 , membrane damage, mitochondrial DNA (mtDNA) integrity, morphology, phenotype and cytokine secretion

201 ey matter volume (n = 1157) and white matter integrity (n = 1089) between depressed individuals and c

202 ders is similarly associated with functional integrity of 2 brain networks widely implicated in suppo

203 hey were first shown to preserve the barrier integrity of airway epithelial cells better than the hum

204 on of Hand2 and Shh gene dosage improves the integrity of anterior limb structures, validating the im

205 The SDMC enhances the scientific integrity of ARLG studies through the development and im

206 The significantly better interlayer integrity of BN nanosheets makes them a more attractive

207 s by 4-PBA may play a beneficial role on the integrity of BSCB in diabetic SCI rats, leading to impro

208 s (DM) impairs endothelial cell function and integrity of BSCS.

209 ammatory cytokines and influences epithelial integrity of cholangiocytes.

210 manufacturing problems, such as compromised integrity of coated pellets and poor content uniformity.

211 tion of full-length FZD4, which requires the integrity of CRD palmitoleoyl-binding residues.

212 trates that harvesting techniques affect the integrity of different vein layers, albeit only slightly

213 chromatin landscape to ensure the epigenomic integrity of dividing cells.

214 that pressure cannot compromise the covalent integrity of DNA.

215 and hence, a prerequisite is the quality and integrity of DNA.

216 The organization and integrity of epithelial tight junctions depend on intera

217 equence and structural features (measured by integrity of epitopes on the Env trimer) in a geographic

218 ible research is important for assessing the integrity of findings and disseminating methods, but it

219 rmline to DNA damage, thereby protecting the integrity of gamete genomes that are passed on to the ne

220 Whole brain white matter integrity of HD-monkeys was examined longitudinally from

221 measurements demonstrate that the mechanical integrity of individual BNNTs remain intact after being

222 The functional integrity of lamin and nesprin-1 is thus required to mod

223 ors that function to maintain the structural integrity of NMJs.

224 The integrity of our DNA is challenged with at least 100,000

225 ation events occur, in order to preserve the integrity of protein synthesis.

226 fect the activity, stability, and structural integrity of proteins.

227 ive stress is negatively correlated with the integrity of PVIs and the extracellular perineuronal net

228 of nonpolar driving forces on the structural integrity of secondary plant cell walls.

229 Yet the integrity of sensory systems determines effective percep

230 imb locomotion was restored by reestablished integrity of submidbrain circuits of serotonergic reticu

231 of neurotoxicity critically impinging on the integrity of the actin cytoskeleton.

232 Integrity of the airway epithelium is essential for norm

233 ant patients and might affect the structural integrity of the airway, which needs further investigati

234 Bag6 nuclear localization and the functional integrity of the Bag6 complex in the cytosol.

235 The integrity of the barrier depends on spatial control of d

236 in on the cell surface is critical to ensure integrity of the blood filtration barrier.

237 conditions, without compromising structural integrity of the catalyst framework.

238 be dissipated without loss of the molecular integrity of the chemical filter.

239 rin repeats that are required for structural integrity of the conoid, parasite motility, and host cel

240 cross-links can be mutagenic by damaging the integrity of the DNA structure.

241 muscle use due to the compromised structural integrity of the dystrophin associated glycoprotein comp

242 using microchip confirmed better quality and integrity of the extracted DNA as opposed to the convent

243 pacity allows monitoring of the position and integrity of the filter, thereby increasing its safety a

244 While maintaining the integrity of the genome and sustaining bioenergetics are

245 ssociated with markers of myeloarchitectural integrity of the insular cortex, while affective empathy

246 Moreover, ragweed did not affect the integrity of the intestinal epithelial cells.

247 ell as strain KM2501-1 itself, destroyed the integrity of the intestine and pharynx.

248 (OR, 3.66; 95% CI, 1.40-9.62; P = 0.01), and integrity of the IS-OS layer (OR, 2.09; 95% CI, 1.30-3.3

249 the meaning of a new word is related to the integrity of the language-related white matter pathways

250 denylation of 16S mt-rRNA did not affect the integrity of the mitoribosome, spurious poly(A) addition

251 n the substantia nigra (SN) and affected the integrity of the nigrostriatal system.

252 ositive correlation between the white matter integrity of the pons and cerebellar gray matter volume

253 2) imaging with PET allows assessment of the integrity of the presynaptic dopaminergic pathway.

254 between arms correlated negatively with the integrity of the primary sensorimotor network and cortic

255 rization rate, myosin contractility, and the integrity of the putative microtubule-based barrier at t

256 urrent exchange mechanism and the structural integrity of the renal medulla.

257 Overall, our findings demonstrate that integrity of the respiratory epithelium is crucial in th

258 may represent a surrogate biomarker for the integrity of the retinohypothalamic tract, with potentia

259 Furthermore, the integrity of the skeleton of cidaroids has never been as

260 timal collective influence to the structural integrity of the social network, is highly correlated wi

261 organ/tissue digestion, while protecting the integrity of the target cells.

262 odels, little is known concerning structural integrity of the transgene, precise site of integration,

263 cardiomyocyte plasticity and to preserve the integrity of the ventricular chamber.

264 component of the divisome that promotes the integrity of the Z ring by acting through ZapB and raise

265 spontaneous neuronal activity and functional integrity of these impacted neural networks in primary p

266 cetaminophen, even at low-dose, disrupts the integrity of TJ and cell-matrix adhesions, with indicato

267 Electron microscopy shows structural integrity of transferred membranes with thickness of 100

268 e surrounding environment and the structural integrity, offering numerous opportunities for biosensin

269 vestigate the impact of plasma membrane (PM) integrity on bacterial replication in different function

270 defects in epithelial proliferation, barrier integrity, or ultrastructure.

271 ant challenge to genome stability and genome integrity over the life of a cell or organism.

272 though they did not show progressive loss of integrity over time.

273 We showed an age-dependent modulation of BBB integrity parameters suggesting increased BBB permeabili

274 nthesis, as well as the activity of the cell integrity pathway and its core element, the MAPK Pmk1.

275 with proper downstream signaling to the cell integrity pathway via Pck2.

276 gen species production, gene expression, DNA integrity, proliferation, and viability.

277 tenance of both lens transparency and muscle integrity remain unclear.

278 entrosome number regulation and spindle pole integrity specifically in mES cells.

279 nct and novel role for IFT56 in IFTB complex integrity that is crucial for cilia structure and functi

280 loss, elevated levels of markers of synaptic integrity that was linked to improved cognition and in a

281 Collagen XIII was found to affect synaptic integrity through binding the ColQ tail of acetylcholine

282 esponse to lung injury, restoring epithelial integrity through spreading and migration.

283 observable RNA quality parameters (i.e. RNA integrity), thus this confounding relationship was stati

284 quired for endothelial Wnt signaling and BBB integrity under pathological conditions in adult mice.

285 We evaluated mitochondrial integrity using MitoTracker Green and cytosolic ATP leve

286 roteins were lost from the CMs, and membrane integrity was compromised.

287 The stereochemical integrity was fully preserved throughout the synthesis,

288 l death indicating that the loss in membrane integrity was not an epiphenomenon.

289 Once formed, membrane permeability (integrity) was unaffected by minerals.

290 s and size of tumors, and intestinal barrier integrity were assessed by histologic, immunohistochemic

291 regulates oxidative phosphorylation and cell integrity, whereas loss of NLRX1 results in increased ox

292 disease and maintained lung and spleen organ integrity, which was accompanied by a reduced mycobacter

293 the vascular wall to help preserve vascular integrity while coordinating host defense.

294 n expression and enhances epithelial barrier integrity, while knockdown of USP48 attenuates TNF-alpha

295 ivated TH1 and TH2 cells impaired epithelial integrity, while treatment with anti-TNF-alpha or anti-I

296 Intact white matter integrity with decreased NAA/Cr levels suggests that mit

297 elicases are important maintainers of genome integrity with distinct roles in almost every cellular p

298 on destruction of the respiratory epithelium integrity with EGTA or N-acetylcysteine.

299 cleotides represent a major threat to genome integrity with the potential to cause strand breaks.

300 a coordinated manner that maintained vessel integrity, with no loss of barrier function.