ライフサイエンスコーパス: intensify

1 thracycline-based regimens (conventional and intensified).

2 re increasingly related as flooding duration intensified.

3 lture problems have increased as farming has intensified.

4 ter the anti-reflux regimen has been further intensified.

5 mination can the condensation be effectively intensified.

6 elevated [CO2] diminished to zero as drought intensified.

7 weak when certain key routine activities are intensified.

8 er the past century as human activities have intensified.

9 l mucosal homeostasis when the TLR signaling intensifies.

10 ontinue as research in this burgeoning field intensifies.

11 me increasingly important as this phenomenon intensifies.

12 from a small number of patients (n = 6), an intensified 16-week regimen of elbasvir and grazoprevir

13 and metal insertion leads to red-shifted and intensified absorption features.

14 r, and weeks or days for a PWID tamperer who intensifies access to opioids.

15 gesting that further gains are possible with intensified actions.

16 utine immunization (RI) activities, began to intensify activities to strengthen RI.

17 enefit from allogeneic SCT in the context of intensified adult ALL therapy.

18 n the secretory stage, lowered chloride, and intensified Ae2 immunostaining in the enamel organ in co

19 ersely, activation of alpha2A-adrenoreceptor intensified aforementioned degenerative changes in UAC r

20 to P inputs, given increasing pressures for intensified agricultural production.

21 nhanced P exports from growing urbanization, intensified agriculture, or climatic change.

22 Efforts need to be intensified along the food chain to reduce Campylobacter

23 production to vascular hyperpermeability and intensified anaphylactic responses in female mice, provi

24 Mycophenolate mofetil at intensified and individually adjusted dose in combinatio

25 haploid selection to predict when evolution intensifies and when it dampens the "selective arena" wi

26 suggests that western boundary currents will intensify and shift poleward as a result.

27 Inflammatory conditions intensify and then resolve, often sparing and recovering

28 From 2200 bp land cover change intensified, and the broad pattern of land cover for pre

29 tism displayed by unordered magnetic moments intensifies, and these magnetic moments align in paralle

30 cency but rather a renewed effort to expand, intensify, and maximize their impact.

31 ariations in hospitals' rates of initiating, intensifying, and maximizing statin therapy after acute

32 romaticity are fortified, whereas those that intensify antiaromaticity or disrupt aromaticity are wea

33 latory CD28 molecules with recently reported intensified antigen thresholds of antigen-experienced CD

34 mined the association between initiating and intensifying antihypertensive medication and serious fal

35 nd 9 CVAs in the 25 patients who remained on intensified antithrombotic therapy alone.

36 s widely, ranging from watchful waiting with intensified antithrombotic therapy to early surgical dev

37 Intensified antituberculosis treatment was not associate

38 We hypothesized that intensified antituberculosis treatment would enhance the

39 ceptible TBM treated with either standard or intensified antituberculosis treatment.

40 Overall, habitat degradation is likely to intensify as a major driver of marine wildlife loss.

41 t that marine defaunation rates will rapidly intensify as human use of the oceans industrializes.

42 agriculture practices were most suitable for intensifying as well as diversifying wheat-rice rotation

43 astrulation, when BMP signaling broadens and intensifies at the edge of the germ rudiment in Megaseli

44 pes associated with high aerosol burdens are intensifying (becoming more warm and humid), and thus ch

45 creasing breath acetone levels that indicate intensified body fat metabolism, as validated by paralle

46 ating in the 1920, s when pig production was intensified, but no consistent genomic differences betwe

47 protein pupylation is required, this bias is intensified by depletion of free Dop molecules, thereby

48 The latter effects are intensified by diminished interaction with AP-2, impedin

49 Water scarcity is intensified by drought, a phenomenon that impacts many s

50 ntly rage across Mediterranean Europe, often intensified by high temperatures and droughts.

51 y virus (HIV) infection but paradoxically is intensified by HIV-associated antiretroviral therapy (AR

52 05 nm light induced moderate pain, which was intensified by pretreatment with aminolevulinic acid.

53 This may be intensified by seasonality, as wet season conditions can

54 ality between eastern Africa and Eurasia had intensified by ~9 Ma, with decreased faunal interchange

55 As agricultural activity intensified ca. 2200 cal.

56 in real time, revealing that LRRD unfolding intensifies Ca(2+) signal whereas MSD unfolding affects

57 -photon imaging system based on a time-gated intensified camera from which the image of an object can

58 array and the other system on a time-gated, intensified camera.

59 nsion of access to tuberculosis care through intensified case finding (South Africa only).

60 losis screening to improve the efficiency of intensified case finding and increase uptake of tubercul

61 ndemic areas and thus poor implementation of intensified case finding and tuberculosis preventive the

62 ich is likely to increase as permafrost thaw intensifies causing positive climate feedbacks in respon

63 LED for low-power, pulsed excitation and an intensified CCD camera for gated detection.

64 10Hz) attached to echelle spectrometer with intensified charged coupled device (ICCD).

65 ctions, so-called second-look surgeries, and intensified chemoradiotherapy.

66 These patients may benefit from intensified chemotherapy regimens or, ideally, should en

67 Attempts to intensify chemotherapy in aggressive non-Hodgkin lymphom

68 hoblastic leukemia (ALL) improved greatly by intensifying chemotherapy for all patients.

69 Intensified clustering promoted the initiation of synchr

70 e to greenhouse warming has been proposed to intensify coastal upwelling by strengthening alongshore

71 ntact CMNs increased target dry weight (DW), intensified competition and increased size inequality.

72 We predicted that by intensifying competition for help, our manipulation woul

73 retards the evolution of drug resistance by intensifying competitive interactions between susceptibl

74 lent achievements obtained during 5 years of intensified control efforts totally vanished in only 2 t

75 We argue that Saharan warming intensifies convection within Sahelian MCSs through incr

76 not been documented with any other means of intensified conventional insulin delivery.

77 for integrating non-Western data sources and intensifying cooperation to more effectively address soc

78 Second, as matching difficulty intensified, cross-hemispheric functional connectivity (

79 iods of protein malnutrition may enhance (or intensify) cryptosporidiosis by suppressing C. parvum-in

80 eriod 700-50 BC, and attribute the onset of intensified Cu smelting in South America to the activiti

81 ults provide an additional mechanism for why intensified density-independent mortality (via harvest o

82 terferon-gamma values (>4.00 IU/mL) warrants intensified diagnostic and preventive intervention becau

83 esions are malignant, what warrants further, intensified diagnostics.

84 t IR injury in T1D is more severe because it intensifies differential epigenetic markers and neuro-gl

85 Phase 2 resolved after we implemented an intensified disinfection protocol and used sterile water

86 t conventional doses) and 55 received a dose-intensified, dose-dense concomitant regimen of epirubici

87 We aimed to assess the effect of an intensified dosing schedule of subcutaneous methotrexate

88 The route of administration and the intensified dosing schedule should be considered when me

89 or 72 h continuous intravenous infusion) or intensified doxorubicin (75 mg/m(2); 25 mg/m(2) per day,

90 Our results do not support the use of intensified doxorubicin and ifosfamide for palliation of

91 easing rates of atmospheric N deposition and intensifying droughts, NO gas evasion may become an incr

92 ve therapy for infectious diseases, has been intensified due to their high content of antimicrobial a

93 O2 phase on charge to 4.55 V vs Li(+)/Li and intensified during further charge to 4.7 V vs Li(+)/Li d

94 iated exchanges of species has substantially intensified during the last centuries, we know surprisin

95 e mechanism by which the C57BL/6J background intensifies dysferlinopathy, giving rise to a more sever

96 The cytokine storm is an intensified, dysregulated, tissue-injurious inflammatory

97 rto unrecognized feedback where persistently intensified East Asian summer monsoon during the late Pl

98 Intensified efforts are needed to identify and link HIV-

99 Intensified efforts to promote protective T cell-based i

100 k continues, but it is being supplemented by intensified efforts to study how conceptual systems and

101 counties should prove valuable for China to intensify efforts for those with unacceptably high under

102 oups, and on how best to sustain, focus, and intensify efforts to progress for this and future genera

103 Adolescence is a time of intensified emotional experiences, during which anxiety

104 may guide prioritization of some regions for intensified engagement with the private sector.

105 both cell death and regrowth impairment were intensified enough to achieve complete remission, and ad

106 rease in hepcidin augments iron delivery for intensified erythropoiesis.

107 Elevated levels of VAMP7 markedly intensified ESR1-potentiated transcriptional activity by

108 a-H2AX, triggering nuclear translocation and intensified expression of AIF.

109 within farmland landscapes, and land sparing intensifies farming to allow the offset of natural reser

110 Under intensified fire regimes, dispersal limitation of evergr

111 Intensifying fire regimes due to climate change may caus

112 To better understand the consequences of intensifying fire regimes in boreal forests, we studied

113 ing activities, and forest fragmentation may intensify fires in Amazonia by altering forest microclim

114 or when oral lipid-lowering therapy (LLT) is intensified first.

115 Devil rays (Mobula spp.) face intensifying fishing pressure to meet the ongoing intern

116 ings who did not proceed to biopsy underwent intensified follow-up for at least 18 months.

117 Air monitoring across the WIPP site intensified following the first reports of radiation det

118 appropriately reduced for some patients and intensified for others.

119 We show that the magnitude of MMEs has been intensifying for birds, fishes, and marine invertebrates

120 water resources in all three aquifer systems intensified from 2000 to 2008, making it imperative that

121 The rate of acidification intensifies from -0.006 +/- 0.007 pH units per decade (b

122 nisms, ranging from orography to convection, intensifying fronts, and even seismic and volcanic event

123 ated moment-to-moment aggression-seeking and intensified future attack.

124 cost, the phosphorus fertilizer required to intensify global crop production atop phosphorus-fixing

125 rms a soft barrier to passive diffusion that intensifies gradually with increasing molecular mass in

126 P-ALL (median age, 38 years), treated in the intensified Group for Research on Adult Acute Lymphoblas

127 With intensified group-level competition, larger populations

128 Tree regeneration failure due to intensified growing season dryness and increased area bu

129 Genetic loss of Gcn2 intensified hepatic PERK activation to asparaginase, yet

130 ident HF in blacks and represent targets for intensified HF prevention.

131 suggest that cue-triggered reward expectancy intensifies hippocampal output to target structures, suc

132 Rapid climate change and intensified human activities have resulted in water tabl

133 f age): 612 had documented responsiveness to intensified immunosuppression (IIS), 1155 had kidney bio

134 Local skin reactions were most intensified in AFXL-pretreated skin and correlated with

135 ts with undetectable MRD (standard risk) and intensified in patients with intermediate (medium risk)

136 rds and mammals suggest these movements have intensified in recent decades.

137 the end of the snow-free season, and it has intensified in recent years, coinciding which a change i

138 ruling out the possibility that rainfall has intensified in response to locally warmer conditions.

139 global vegetation productivity patterns has intensified in response to recent global warming.

140 ectional selection on timing of reproduction intensified in the first two decades (1980-2000) but wea

141 hroughout Malawi began in the late 1990s and intensified in the latter half of the 2000s and into the

142 e perversely intense, widespread and rapidly intensifying in places with high biodiversity.

143 densities of MRSA were inversely related to intensified infection prevention and control, but positi

144 AK) are rare and have never been compared to intensified insulin therapy (IIT).

145 and who would otherwise delay initiating or intensifying insulin therapy because they are unwilling

146 l require a similar investment of effort and intensified inter-disciplinary communication.

147 , a hydrogen bond between amine and catalyst intensifies interactions around the palladium and orient

148 hange, rising human population densities and intensifying international trade will allow these costly

149 d to improve breastfeeding practices through intensified interpersonal counseling (IPC), mass media (

150 arly the case over the last 6,000 years when intensified intertidal shellfish usage resulted in the a

151 iraemia among serodiscordant couples warrant intensified interventions.

152 udy evaluated the population-level impact of intensified IPC, MM, CM, and PA (intensive) compared to

153 iated adhesion modulates TCR-pMHC tension by intensifying its magnitude to values >19 pN and spatiall

154 kya), Earth's orbitally paced ice age cycles intensified, lengthened from approximately 40,000 ( appr

155 MTB mRNA in the context of nonresolving and intensifying lesions on PET-CT images might indicate ong

156 The gap waveguide intensifies light by nanofocusing it to a mode cross-sec

157 Despite the use of intensified LLT, many FH patients continue to experience

158 After intensified local corticosteroid therapy, most patients

159 smonic substrates, resulting in dramatically intensified LSPR between adjacent nanoparticles as compa

160 Degradation of water quality by intensified mammoth activity around the lake likely exac

161 d modern humans, and considered adaptive for intensified manual manipulation.

162 We found that the history of LCMV infection intensifies MCMV immunopathology, enhances MCMV burden i

163 t ensure rapid uptake in target populations, intensified mechanisms for information management, surve

164 matic fluctuations in the gut microbiome and intensified medication due to a flare of the disease.

165 gesting that, in control plots, AM roots may intensify microbial competition for nutrients.

166 Intensifying midcontinental socio-political instability

167 The use of an agent that intensifies mitochondrial oxidative stress in combinatio

168 s the need for renal preventive measures and intensified monitoring for emerging CVD, particularly in

169 iers of these variants could be placed under intensified monitoring or offered alternative treatment

170 Our record reveals a gradually intensifying monsoon from 14.7-7.0 ka, a maximum monsoon

171 gimen coupled with tacrolimus (Tac) and dose-intensified mycophenolate mofetil (MMF) further adjusted

172 or inhibition of SHP2 in macrophages causes intensified NLRP3 activation, overproduction of proinfla

173 Coincidently, p58(IPK) deletion intensified NLRP3-inflammasome activation indicated by e

174 left ventricular ejection fraction</=45% to intensified, NT-proBNP-guided versus standard, symptom-g

175 At night, UHI warming intensifies, occurring across a majority (90%) of India'

176 ome of the IR vibrational bands are strongly intensified on oxidation, and Fano-type antiresonances a

177 ignificant changes one day after surgery and intensifies one day later, thus indicating a systemic ph

178 an decide whether symptomatic therapy can be intensified or allergy immunotherapy should be administe

179 s of withdrawal, cue-induced cocaine craving intensifies, or "incubates," and persists over extended

180 f spatial feedbacks also was significant and intensified over ecosystem succession, as a resource (ni

181 Here we show that during El Nino, typhoons intensify over region undergoing strong ocean subsurface

182 ms as warming and freshening is projected to intensify over the coming century.

183 Macromolecular crowding intensifies oxidative modifications of WP, as well as fo

184 rphyrin-like UV-vis spectrum with a slightly intensified peak at 650 nm.

185 With intensified pediatric-like therapy and genetic disease d

186 mmend that clinicians consider initiating or intensifying pharmacologic treatment in adults aged 60 y

187 mmend that clinicians consider initiating or intensifying pharmacologic treatment in some adults aged

188 Efforts to intensify pharmacological blockade by use of dual inhibi

189 nia patient lymphoblasts, thereby leading to intensified PKR activation and enhanced cellular death.

190 eeding beyond 30 days, supporting the use of intensified platelet inhibition during the first year af

191 As water scarcity intensifies, point-of-use and point-of-entry treatment m

192 2012 to date, Nigeria has been the focus of intensified polio eradication efforts.

193 d the EURAMOS-1 trial to investigate whether intensified postoperative chemotherapy for patients whos

194 Early intensified postoperative topical steroid therapy consti

195 n across the HLA-barrier, with the use of an intensified posttransplant immunosuppressive therapy sta

196 rvival (OS) while preserving renal tissue by intensifying preoperative chemotherapy, completing defin

197 This highlights that intensified prevention strategies are required to delay

198 and identify the highest-risk subgroups for intensified prevention, such as pre-exposure prophylaxis

199 Future efforts could intensify primary prevention aimed at young adults, adol

200 structures, this expectancy-related state of intensified processing in the hippocampus may modulate g

201 burden of unrepaired endogenous DNA lesions intensifies, progressively leading to genomic instabilit

202 itation are projected to dominate gains from intensifying projected extreme precipitation.

203 nt, reaction time, and temperature led to an intensified protocol at elevated temperatures that allow

204 ntensification, and were much more likely to intensify rapidly.

205 ies on our planet's natural systems has been intensifying rapidly in the past several decades, leadin

206 th has been the subject of debate, which has intensified recently with the suggestion that the stripe

207 per kilogram of body weight per day) with an intensified regimen that included higher-dose rifampin (

208 (containing rifampicin 10 mg/kg/day) with an intensified regimen with higher-dose rifampicin (15 mg/k

209 utlines 3 areas of emphasis, one of which is intensified research and innovation.

210 ural pesticide application practices and for intensified research efforts on the presence and effects

211 rmed a group working toward a common goal of intensified research to facilitate the development of ne

212 his is a retrospective study to document the intensified resource mobilization efforts made by the Wo

213 air gun had no effect, but repeated exposure intensified responses.

214 radical prostatectomy may benefit from dose-intensified salvage radiation therapy (SRT) of the prost

215 By intensifying sampling of geographically distinct populat

216 sk prediction models and into guidelines for intensified screening and follow-up.

217 ased risk in this group of patients, such as intensified screening or vaccination, are warranted.

218 d selection, which are followed by phases of intensified selection and rate deceleration in the retai

219 film or graphene surface show significantly intensified SERS signals due to vertical plasmonic coupl

220 Therefore, research on this topic has intensified significantly during the past 10 years and t

221 In Papua New Guinea, vector control has been intensified since 2008, and improved diagnosis and treat

222 Agricultural activities have intensified since the 1980s to provide food security to

223 se expectations, the Agulhas Current has not intensified since the early 1990s.

224 As efforts to control the disease have intensified, so has the selection pressure on mosquitoes

225 In turn, increased ocean rafting may intensify species invasions.

226 The impact of dose-intensified SRT on QoL was minor, except for a significa

227 Dose-intensified SRT was associated with low rates of acute g

228 ely 500 y indicates that climate warming and intensifying stratification have almost certainly reduce

229 fall in places where typhoons form, tends to intensify STYs by reducing their ability to cool the upp

230 To ensure long-term ART success, intensified support for adherence, VL and drug resistanc

231 ice, extension of the seasonal sea ice zone, intensified surface ocean stratification and shifts in p

232 Participants underwent 2 years of intensified surveillance including biannual AB US, and r

233 without any paralytic cases as determined by intensified surveillance of environmental and human samp

234 Consequently, we find that fast tonic firing intensifies synaptically driven burst firing output in d

235 Research in these areas has recently intensified, thanks to advances in chemical synthesis, i

236 Depending on position, A/APs diminished or intensified the damaging effect of the G/APs.

237 relevance today-namely, that fear and panic intensified the disruption of society and damage to the

238 of natural origin on aquatic ecosystems have intensified the need for predictive and functional model

239 ources supplied to microorganisms, and thus, intensified the pressure of ecological filtering, favori

240 dvances in subunit vaccines development have intensified the search for potent adjuvants, particularl

241 Stimulation intensifies the hormonal milieu characterizing SWS (main

242 pain, the BMI training with the phantom hand intensifies the pain.

243 findings show that integrin beta3 signaling intensifies the suppressive effect of IFNgamma on HSCs,

244 The treatment of cells with coating agents intensifies the torque induced on the cells while reduci

245 eatment in bladder carcinoma cells, and thus intensifies the understanding of HSP90 inhibition-mediat

246 However, there is a need to intensify the efforts in order to increase the data avai

247 ngth, indicating that preferred orientations intensify the enhancements in strength that accompany gr

248 egS that acts at picomolar concentrations to intensify the intracellular response to glutamatergic si

249 Molecules that attenuate/intensify the magnitude of these signals are considered

250 ium infection, which highlighted the need to intensify the subsequent strategies.

251 agment show unique transformations by either intensifying the alpha helical structure or changing fro

252 y by exacerbating pulmonary inflammation and intensifying the fibrotic response in the patients.

253 Climate change is intensifying the hydrologic cycle and is expected to inc

254 iance in terrestrial systems(5), potentially intensifying the importance of UV-mediated selection to

255 use most of the deaths from prostate cancer, intensifying the need to fully understand CRPC pathophys

256 Migraineurs avoid light because it intensifies their headache.

257 D at 3 and 4 years, thus suggesting that the intensified therapy altered the disease course of MRD-po

258 Intensified therapy given to subjects with MRD >0.1% did

259 wever, selection of appropriate patients for intensified therapy remains challenging, particularly in

260 that identifies a poor-risk group warranting intensified therapy.

261 These findings could be used to tailor and intensify therapy in these patients, for whom current th

262 LPS to stimulate TLR4, suggesting that MMTV intensifies these immunostimulatory properties.

263 raltegravir induction for first 12 weeks, re-intensified to combination therapy after week 96; protea

264 Intensified topical corticosteroid therapy was started i

265 As expected, populations that did not intensify tOPV use prior to OPV2 cessation show continue

266 As human populations increase and land-use intensifies, toxic and unsightly nuisance blooms of alga

267 he Indonesian throughflow in response to the intensified trade winds in the equatorial Pacific.

268 KEY POINTS: Three weeks of intensified training and mild energy deficit in elite ra

269 CHO), high fat diet (LCHF) during 3 weeks of intensified training on metabolism and performance of wo

270 suPAR levels before and after the course of intensified treatment (3814 +/- 908 to 3595 +/- 521 pg/m

271 Early intensified treatment improved survival in patients with

272 iding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure (GUIDE-IT) study

273 Purpose To assess an intensified treatment in the context of clinical and bio

274 ence of a significant differential effect of intensified treatment in the overall population or in an

275 ly published randomized trial, compared with intensified treatment of midgut NETs with long-acting an

276 ected for treatment adjustments, showed that intensified treatment was significantly associated with

277 ome by resistance categories and response to intensified treatment were compared and estimated by Cox

278 s met the primary endpoint; 47 had VF, and 2 intensified treatment without VF.

279 Of the 47 subjects with VF, 41 (33%) intensified treatment, and 39 of 41 subsequently achieve

280 rd regimen, and 408 were assigned to receive intensified treatment.

281 A number of methods for intensifying treatment of HNSCC have been investigated,

282 e 9 months of follow-up, 113 patients in the intensified-treatment group and 114 patients in the stan

283 tandard-treatment group and 95 events in the intensified-treatment group, P=0.08).

284 The hydrological cycle is expected to intensify under global warming, with studies reporting m

285 pply and carbon sequestration is expected to intensify under higher greenhouse gas emission and assoc

286 lgorithms, in which therapy is progressively intensified until a specific treatment goal is reached.

287 Trial of Intensified versus standard Medical therapy in Elderly p

288 ions of abrasive particles in the context of intensified volcanism and increasing aridity.

289 or releasing E. coli to surface water during intensified wave conditions at a fine sand beach, compar

290 the Central American Gap Winds (CAGW), which intensify (weaken) during El Nino (La Nina), producing l

291 with increased terrestrial productivity and intensified weathering by the first land plants.

292 ecting the periorbital area and the eye, and intensifies when intracranial pressure increases.

293 These results indicate that intensifying winds may be increasing the eddy kinetic en

294 latent heat energy to transient eddy energy, intensifying winter cyclogenesis via moist baroclinic in

295 th an increased risk of type 2 diabetes that intensified with increasing duration of use, cumulative

296 the headache develops, it typically throbs, intensifies with an increase in intracranial pressure, a

297 ween plants and nitrogen (N)-fixing rhizobia intensify with decreasing N supply and come at a carbon

298 Although evapotranspiration is expected to intensify with increasing temperatures, long-term, regio

299 ence that selection due to climate change is intensifying, with far-reaching consequences for demogra

300 d variability as glacial-interglacial change intensified worldwide.