ライフサイエンスコーパス: intensive

1 nal PCR-based methods are laborious and time-intensive.

2 ire expensive instrumentation and are labour-intensive.

3 nthesis from N2 and H2 is notoriously energy intensive.

4 fication are exceedingly energy and chemical intensive.

5 terial cultures are time-consuming and labor-intensive.

6 ain challenging, often invasive and resource-intensive.

7 ore often costly and resource/infrastructure intensive.

8 Intensive 24-hour pharmacokinetic sampling was performed

9 upper reaches and middle reaches because of intensive agricultural activities and urban input.

10 roduction and lower environmental costs from intensive agriculture in Jiangsu, China.

11 to large-scale deforestation, extensive and intensive agriculture, resource mining, livestock grazin

12 of all ICU-related revenue center codes for intensive and coronary care, excluding nursery, intermed

13 d that seeds could replace other more labour intensive and costly methods, such as transplanting adul

14 ing a minority was associated with receiving intensive and invasive end-of-life care among patients w

15 intraoperative histology are time- and labor-intensive and often introduce artifact that limit interp

16 wever, these techniques are relatively labor-intensive and require a significant amount of training.

17 xisting technologies remain extremely energy intensive and require large capital investments.

18 However, it is labor intensive and requires large volumes of human milk.

19 These are computationally intensive and time consuming steps, which are not ideall

20 ogistical challenge, as the process is labor intensive and time consuming.

21 rder of magnitude for that of the more labor-intensive and time-consuming cell-assay technique, 2.0 m

22 s readers and imaging systems, which require intensive and time-consuming procedures.

23 tictal symptoms lasting up to 8 wk displayed intensive and widespread (>/= 1 lobe) cortical (18)F-FET

24 r belatacept more-intensive, belatacept less-intensive, and cyclosporine, respectively (belatacept mo

25 histologic methods is time consuming, labor intensive, and dependent upon investigators' expertise a

26 s utility, ELISA is time-consuming, resource-intensive, and infrastructure-dependent, limiting its av

27 aimed to compare the safety and efficacy of intensive antiplatelet therapy (combined aspirin, clopid

28 severe symptomatic atherosclerosis and more intensive antiplatelet therapy reduces VTE risk beyond a

29 By contrast, intensive antiplatelet therapy was associated with more,

30 easing interest in various data- and compute-intensive applications such as phylogenetic inference fo

31 emographics may effectively complement labor-intensive approaches, with the potential to measure demo

32 rs, the overall survival rate was 57% in the intensive arm and 47% in the standard arm ( P = .092).

33 a and thrombocytopenia were prolonged in the intensive arm, but there were no differences in serious

34 clerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL ch

35 n carbide nanowires (SiC NWs) have attracted intensive attention in recent years due to their outstan

36 and a convenient alternative to, the labour-intensive basal-bolus insulin regimen for the management

37 Earlier access to intensive behavioral intervention (IBI) is associated wi

38 er and offer or refer them to comprehensive, intensive behavioral interventions to promote improvemen

39 22.8%, 37.0%, and 25.8% for belatacept more-intensive, belatacept less-intensive, and cyclosporine,

40 on might be in the current era in which data-intensive biomedical characterization of individuals is

41 It is currently unknown whether intensive blood pressure (BP) lowering beyond that recom

42 s differential reduction in ADHF events from intensive blood pressure [BP] treatment among the 6 key,

43 d the prognostic significance of dIVH in the Intensive Blood Pressure Reduction in Acute Cerebral Hae

44 est that the benefit or risk associated with intensive blood pressure-lowering treatment can be estab

45 d by individual findings), and a CF-specific intensive bowel preparation.

46 In older hypertensive patients, intensive BP control (systolic BP <140 mm Hg) decreased

47 tervention Trial): 4086 randomly assigned to intensive BP lowering (target SBP <120 mm Hg) and 4078 a

48 with hypertension but no diabetes mellitus, intensive BP lowering (target systolic BP <120 mm Hg) co

49 nal function that should be tolerated during intensive BP lowering and its association with risk of E

50 the acute declines in kidney function in the intensive BP lowering arm of two trials in CKD associate

51 Thus, acute eGFR declines >/=20% during intensive BP lowering identified a subset of patients at

52 d controlled trials (RCTs) to assess whether intensive BP lowering in patients with acute ICH is safe

53 ted cardiovascular disease (CVD) benefits of intensive BP lowering in this population.

54 The effect of intensive BP lowering on significant haematoma expansion

55 Intensive BP lowering was associated with a 29% reductio

56 versus higher ARRs in CVD events/deaths with intensive BP treatment, and participants who had lower v

57 patients with acute ICH randomised to either intensive BP-lowering or standard BP-lowering treatment

58 y was similar between patients randomised to intensive BP-lowering treatment and standard BP-lowering

59 Intensive BP-lowering treatment showed a (non-significan

60 he study therefore provides no evidence that intensive breeding has had negative effects on the conte

61 ospital (median, 15 vs 25 days; P < .01) and intensive care (10 vs 17 days; P = .04) than those treat

62 % CI 0.28 to 0.90; p=0.0210), fewer neonatal intensive care admissions lasting more than 24 h (0.48;

63 ompt antitoxin administration and meticulous intensive care are essential for optimal outcome.

64 es the clinical course of patients requiring intensive care as a result of their primary medical or s

65 ata prospectively collected by the Pediatric Intensive Care Audit Network over 8 years (2007-2014).

66 Although the number of intensive care beds in the United States is increasing,

67 2014 that participated in the Dutch National Intensive Care Evaluation registry.

68 l patients were given appropriate supportive intensive care for what was initially suspected to be se

69 in intrauterine interventions and perinatal intensive care have resulted in increasing numbers of BH

70 ht to characterize the timing, severity, and intensive care management of cytokine release syndrome a

71 re significantly younger and had more severe intensive care medical conditions (hemodynamic, biologic

72 al Care Medicine and the European Society of Intensive Care Medicine.

73 ve patients with sepsis, 11 severity-matched intensive care patients, and 67 healthy donors was prosp

74 Sixty-three ICUs in the Swedish Intensive Care Registry.

75 of patient- and family-centered care in the intensive care setting.

76 of data from the Australian and New Zealand Intensive Care Society Adult Patient Database and a nest

77 identified in the Australian and New Zealand Intensive Care Society Centre for Outcome and Resource E

78 xtracted from the Australian and New Zealand Intensive Care Society Centre for Outcome and Resource E

79 set was associated with shorter hospital and intensive care stays.

80 its first description 50 years ago, no other intensive care syndrome has been as extensively studied

81 istics of patients with cellulitis requiring intensive care treatment are poorly defined.

82 antibiotic selection that was greater in the intensive care unit (77.97% [CI 72.0-83.1] vs 54.73% [CI

83 fty years after the inception of the cardiac intensive care unit (CICU), noncardiovascular illnesses

84 d to questioning of the beneficial effect of intensive care unit (ICU) admission and to a variable IC

85 g chemotherapy in the final 14 days of life, intensive care unit (ICU) admission in the final 30 days

86 workers or the environment to patients in an intensive care unit (ICU) and a high-dependency unit (HD

87 rly populations; studies based solely in the intensive care unit (ICU) and non-English-language artic

88 ity of ventilatory support, NIV failure, and intensive care unit (ICU) mortality.

89 Delirium is a common disorder in Intensive Care Unit (ICU) patients and is associated wit

90 n from a prospective study of critically ill intensive care unit (ICU) patients meeting two of four S

91 To determine the discriminative accuracy of intensive care unit (ICU) physicians and nurses in predi

92 cell transplantation (SCT) recipients to the intensive care unit (ICU) remains controversial, especia

93 ukemia (AML) commonly require support in the intensive care unit (ICU), but risk factors for admissio

94 In the intensive care unit (ICU), orotracheal intubation can be

95 the causes of potentially avoidable surgical intensive care unit (SICU) admissions and disposition de

96 cesarean delivery, breast-feeding, neonatal intensive care unit [NICU] admission, and absence of pet

97 serin may provide the first ever therapy for intensive care unit acquired weakness in patients.

98 ower motor neurons as a novel contributor to intensive care unit acquired weakness.

99 and respiratory support during the neonatal intensive care unit admission.

100 d that subgroup membership is dynamic during intensive care unit admission.

101 ncy department visits, hospitalizations, and intensive care unit admissions).

102 There was no significant difference in Intensive Care Unit admissions, 30 and 90-day mortality,

103 ergency department visits, hospitalizations, intensive care unit admissions, and chemotherapy in the

104 ed serious morbidity, in-hospital mortality, intensive care unit admissions, and cost.

105 2014, we surveyed all Thai hospitals with an intensive care unit and >/=250 beds.

106 ith various stages of ROP: 3 in the neonatal intensive care unit and 1 in the operating room.

107 rst quantitative data on turn quality in the Intensive Care Unit and highlight the need to reinforce

108 ductions in procedural inotrope requirement, intensive care unit and hospital length of stay (6.0 ver

109 and 30-day death/stroke, procedural success, intensive care unit and hospital length-of-stay, and rat

110 bilization of patients in the cardiothoracic intensive care unit and its effect on length of stay has

111 to first physical therapy evaluation in the intensive care unit and the hospital, and mean days of p

112 s (mean [SD] cost, MP $3530 [MP $2410]), and intensive care unit care (mean [SD] cost, MP $7770 [MP $

113 Intensive care unit cost per bloodstream infection accou

114 consciousness and cortical responses in the intensive care unit could alter time-sensitive decisions

115 ake to morbidity through our practice in the intensive care unit each day.

116 mechanical ventilation, and admission to the intensive care unit for patients admitted to hospital fo

117 ng 974 adults admitted to a tertiary medical intensive care unit from February 3, 2015 to May 31, 201

118 particularly those requiring admission to an intensive care unit involving respiratory failure, intub

119 lty in older trauma patients admitted to the intensive care unit is often not feasible using traditio

120 After adjustment for age, intensive care unit level of care, receipt of nephrotoxi

121 (15.40 versus 7.90 days; P = 0.027), and the intensive care unit LOS (5.55 versus 1.19 days; P = 0.03

122 patients 65 years and older admitted to the intensive care unit of a single level I trauma center be

123 view was conducted of adults admitted to the intensive care unit of an American College of Surgeons-v

124 abies with type 1 zone 1 ROP at the Neonatal Intensive Care Unit of the Catholic University, Rome, fr

125 ow/neg) monocytic (M)-MDSCs were expanded in intensive care unit patients with and without sepsis and

126 In a prospective cohort study of intensive care unit patients with respiratory failure an

127 ssociated with high mortality, especially in intensive care unit patients.

128 These professionals are generally intensive care unit physicians with an enhanced focus an

129 death, the occurrence of adverse events, and intensive care unit resource use.

130 The median length of intensive care unit stay (151 vs 117 hours; P < .001), b

131 Median intensive care unit stay was 7 days (interquartile range

132 shorter duration of mechanical ventilation, intensive care unit stay, and inotrope use; and fewer el

133 Duration of ventilation, intensive care unit stay, and mortality (6, 17, and 29%

134 load, duration of mechanical ventilation and intensive care unit stay, electrolyte abnormalities and

135 rt-term (duration of mechanical ventilation, intensive care unit stay, hospital stay, and highest pri

136 atrial fibrillation, bleeding, and length of intensive care unit stay.

137 d increased nosocomial infections, prolonged intensive care unit stays, and poor functional status at

138 Mortality and care in the intensive care unit were not associated with positive FU

139 discussions regarding extended stays in the intensive care unit, prolonged ventilator management, an

140 al hematoma are key risk factors for needing intensive care unit-level care in children with mTBI and

141 ients and families at the end-of-life in the intensive care unit.

142 ll-cause mortality and length of stay in the intensive care unit.

143 s than or equal to 300 mm Hg admitted to the intensive care unit.

144 is a reality of the clinical context of the intensive care unit.

145 , and mortality of sepsis in adult Brazilian intensive care units (ICUs) and association of ICU organ

146 lticenter, randomized trial conducted at 120 intensive care units (ICUs) from 9 countries from Novemb

147 secutive patients admitted for sepsis to two intensive care units (ICUs) in the Netherlands between J

148 nt gram-negative bacteria (MDR-GNB) in adult intensive care units (ICUs).

149 ant PDA was conducted at 3 tertiary neonatal intensive care units and affiliated follow-up programs.

150 ation is still a frightening complication in intensive care units and has a high mortality.

151 y of 350 critically ill patients admitted to intensive care units at an academic medical center to in

152 Medical and Surgical Intensive Care Units at Massachusetts General Hospital (

153 The setting was neonatal intensive care units at The Children's Hospital of Phila

154 ly to receive chemotherapy or be admitted to intensive care units at the end of life.

155 of 441 patients with ARDS admitted to three intensive care units at the University Medical Centre id

156 cutive adult patients admitted to one of two Intensive Care Units between September 2015 to January 2

157 onates admitted to 24 participating neonatal intensive care units from four countries (Australia, Can

158 January 2006 and December 2013 from neonatal intensive care units in 25 US children's hospitals inclu

159 Two Intensive Care Units in a large Academic Medical Center

160 sed, placebo-controlled phase 2 trial in two intensive care units in the UK, involving patients fulfi

161 A major obstacle to therapy in intensive care units is sepsis caused by severe infectio

162 ital cardiac arrest who were hospitalized in intensive care units or general inpatient units were stu

163 2010 and 2011 who were admitted to neonatal intensive care units participating in the Canadian Neona

164 ive Pediatric Critical Care Research Network intensive care units with chest compressions for >/=1 mi

165 ients receiving mechanical ventilation in 36 intensive care units, with daily collection of ventilati

166 cause of morbidity and mortality in neonatal intensive care units.

167 rospective cohort study at tertiary neonatal intensive care units.

168 ions to support surrogate decision-makers in intensive care units.

169 ial performed at 33 US and Canadian neonatal intensive care units.

170 anagement of staphylococcal BSIs in neonatal intensive care units; and (5) defining the impact of VRE

171 and depression during the 3 years following intensive care was 18.0% (95% CI, 17.0-19.0%) for statin

172 In adult patients admitted to intensive care who required acute volume resuscitation,

173 ood leukocytes of adult patients admitted to intensive care with sepsis due to fecal peritonitis (n =

174 tage renal disease, and cirrhosis), need for intensive care, and mortality.

175 lity as requests for resuscitation, neonatal intensive care, and surgical intervention are becoming m

176 ty to other professionals (eg, physicians in intensive care, emergency medicine, neurology, neurosurg

177 of depression and anxiety is elevated after intensive care.

178 birth weight (725 g) neonate EGA 25 weeks in intensive care.

179 rs) and was assessed for the first 7 days of intensive care.

180 We correctly predicted that 8 intensive-care beds and 7 ventilators would be sufficien

181 and surgery services in hospital in the non-intensive-care setting.

182 winter, 2014, in a convenience sample of 459 intensive-care units in 50 countries across six continen

183 In conclusion, combining lestaurtinib with intensive chemotherapy proved feasible in younger patien

184 cutive prospective, randomized, multicenter, intensive chemotherapy trials (AML96, AML2003) from the

185 yeloid leukaemia who were not candidates for intensive chemotherapy.

186 ts Of 2,992 patients, 1,588 (53.1%) received intensive chemotherapy.

187 py and to unfit patients, unable to tolerate intensive chemotherapy.

188 oal combustion provides direct evidence that intensive coal combustion could contribute to increased

189 The incidence rate ratios for the intensive compared with the standard arm (95% confidence

190 ed $13 547 per patient compared with uniform intensive control ($105 307 vs. $118 854), primarily due

191 d be 0.27 higher among patients who received intensive control than among those who received standard

192 and quality-adjusted life-years (QALYs) for intensive control versus standard control of systolic bl

193 d generated more QALYs compared with uniform intensive control, except in analyses where the disutili

194 t and avoidance of certain foods.After a 2-y intensive CR intervention, approximately 50% of CR-induc

195 Five Intensive Critical Care Units affiliated to the Universi

196 e extreme health inequity identified demands intensive cross-sectoral policy and service action to pr

197 These findings suggest that the shift to intensive cultivation and animal husbandry in Estonia wa

198 olding on nuclear processes remain topics of intensive current research.

199 containing millions of particles, leading to intensive debate over the size-dependent microscopic rea

200 However, there is intensive debate regarding whether the relevant coupling

201 a has not experienced mass bleaching despite intensive Degree Heating Weeks (DHW) of >15 degrees C-we

202 actices for this new and dynamic era of data intensive dermatology.

203 Recently, intensive efforts are dedicated to convert and store the

204 sentially as a resonator that accumulates an intensive electromagnetic field into a spiral capacitive

205 All group B patients underwent intensive endurance training for a median of 15 h/week (

206 here too often portray the job of a research-intensive faculty member and principal investigator (PI)

207 D) plus 20 Gy involved-field (IF)-RT to more intensive four cycles of ABVD plus 30 Gy IF-RT was confi

208 INTERPRETATION: More intensive glucose control over 5 years reduced both kidn

209 ter February 2008 when safety concerns about intensive glucose control were reported in the ACCORD tr

210 more precisely estimate the effects of more intensive glucose control, compared with less intensive

211 ntensive glucose control, compared with less intensive glucose control, on the risk of microvascular

212 ications that can be prevented or delayed by intensive glycaemic management.

213 Intensive glycemic control (IGC) targeting HbA1c fails t

214 Individualized versus uniform intensive glycemic control.

215 Participants were exposed to intensive (goal systolic pressure < 120 mm Hg) versus st

216 erate group was 4.8 days vs 3.8 days for the intensive group (absolute difference, -1.0 days; 95% CI,

217 rate group was 12.4 days vs 10.9 days in the intensive group (absolute difference, -1.5 days; 95% CI,

218 After the initial 6 months, the intensive group had a slightly higher rate of change in

219 to 2.2%) and barotrauma incidence (0% in the intensive group vs 0.6% in the moderate group; absolute

220 Hospital mortality (2.5% in the intensive group vs 4.9% in the moderate group; absolute

221 ic adverse events occurred more often in the intensive group.

222 s (p = 0.037) as compared with more resource-intensive ICUs (p = 0.88).

223 Notably, intensive intravenous antibiotic treatment of patients w

224 Despite intensive investigations, mechanisms of liver cancer are

225 etic testing for the premutation is resource intensive, it is not practical to screen individuals for

226 cytometry barcoding approaches require time intensive labeling, reduce the number of biologically me

227 The group with intensive LDL-c-lowering statin had an 18% increase in t

228 To test whether an intensive lifestyle intervention results in equivalent g

229 wer incidence of heart failure compared with intensive lifestyle modification in obese people.

230 existing approaches are both CPU and memory-intensive, limiting their application to small, single d

231 INTRODUCTION: It is unclear whether intensive lowering of blood pressure (BP) at the acute p

232 We found that intensive LULCC occurred in the conterminous United Stat

233 0 CE) as Native American populations adopted intensive maize agriculture, facilitating population agg

234 accurate and effective as traditional labor-intensive measures of flowering time, height, biomass, g

235 oups of similar isolates for computationally intensive methods of phylogenetic inference using (for e

236 rop plants, but requires labor- and resource-intensive methods.

237 lturally competent, youth-friendly care, and intensive motivational interviewing training.

238 t can replace the current energy and capital intensive natural gas conversion process.

239 Random assignment to an intensive or standard SBP goal (120 or 140 mm Hg, respec

240 icipants (N=24) completed two separate 7-day intensive outpatient protocols that included daily visit

241 It can avoid the time intensive parameter tuning if given a reasonable small t

242 We determined that the computationally intensive PBcR-BLASR assembly pipeline yielded better as

243 itiation of dosing, 10 patients underwent an intensive pharmacokinetic evaluation of the concentratio

244 d its metabolite GS-331007 were evaluated by intensive plasma sampling at day 7 in the first 10 patie

245 Here we explore the effects of intensive POM degradation for metal mobilization at the

246 This labor-intensive process could be made easier by automating the

247 eproduction relies upon numerous host energy-intensive processes, the most demanding of which is prot

248 Despite the intensive proliferation, the total cellularity of the CC

249 circuits can be engineered in the absence of intensive purification and/or extensive rounds of design

250 Intensive recent efforts in the development of new react

251 The intensive recruitment strategy group had a mean 1.8 (95%

252 urable plasmonic nanomaterials has become an intensive research area offering the opportunity to reco

253 heir surface chemistry has become a topic of intensive research interest.

254 Intensive research on the genetics, biochemistry, and bi

255 Intensive research over the previous decades has improve

256 ced incidence of coronary heart disease with intensive risk factor management, people with diabetes m

257 Intensive risk factor modification significantly improve

258 chemical denaturation experiments are labour-intensive, sample-costly and time-consuming, and it has

259 und number of deaths prevented per year with intensive SBP control was 34 600 to 179 600.

260 here was no evidence that the benefit of the intensive SBP lowering differed by baseline DBP.

261 Intensive SBP lowering increased risk for incident CKD e

262 If fully implemented in eligible US adults, intensive SBP treatment could prevent approximately 107

263 patients with PLA2R1-associated MN, and more intensive screening for the presence of malignancies may

264 various systems are limited, and there is an intensive search for highly efficient electrocatalysts b

265 Previous reports describe an energy-intensive sintering technique as an alternative techniqu

266 The adoption of less intensive soil cultivation practices is expected to incr

267 Treatment guidelines for aphasia recommend intensive speech and language therapy for chronic (>/=6

268 We aimed to examine whether 3 weeks of intensive speech and language therapy under routine clin

269 ignificantly improved from baseline to after intensive speech and language treatment (mean difference

270 r triplet combinations, or incorporated into intensive strategies with autologous stem cell transplan

271 Intensive study of social phenotypes across species has

272 reduction when monitoring was combined with intensive support.

273 re (DBP), the potential benefits or risks of intensive systolic blood pressure (SBP) lowering are unc

274 cidence of chronic kidney disease (CKD) with intensive systolic blood pressure (SBP) lowering is uncl

275 In this simulation study, intensive systolic blood-pressure control prevented card

276 tandard (systolic BP target <140 mm Hg) with intensive (systolic BP target <120 mm Hg) BP treatment a

277 Despite intensive TB control campaigns, there are sporadic outbr

278 d to a central laboratory for slow and labor intensive tests.

279 tform is significantly faster and less labor intensive than commonly available technologies, making i

280 n patients who received R-CHOP compared with intensive therapy (56% v 88%; P = .002).

281 trial with sequential randomization to more intensive therapy achieved greater than 80% power and un

282 significantly for patients in the R-CHOP or intensive therapy cohorts when analyzed by receipt of au

283 For the 20 patients who received intensive therapy, there was no difference between the p

284 tterns in diverse systems, rigorous testing, intensive time-series datasets and improved stochastic m

285 The process is labor-intensive, time-consuming, and expensive.

286 (up to 2.5) and leaves (0.5), suggesting an intensive transformation of CBZ in these compartments.

287 Whether such intensive treatment affected patient-reported outcomes w

288 reatment, the rate of renal adverse event in intensive treatment group was significantly higher.

289 Participants who received intensive treatment received an average of one additiona

290 .3 to 15.4) lower in the group that received intensive treatment than in the group that received stan

291 Most simulation results indicated that intensive treatment would be cost-effective (51 to 79% b

292 tolic blood pressure of less than 120 mm Hg (intensive treatment) than among those who were assigned

293 ted outcomes among participants who received intensive treatment, which targeted a systolic blood pre

294 ine LVH (n=605, 7.4%), those assigned to the intensive (versus standard) BP lowering were 66% more li

295 More intensive VL monitoring is warranted in this population;

296 cyclosporine, respectively (belatacept more-intensive vs cyclosporine: hazard ratio [HR] = 0.95; 95%

297 val [CI] 0.47-1.92; P = .89; belatacept less-intensive vs cyclosporine: HR = 1.61; 95% CI 0.85-3.05;

298 ecular diagnosis is time-consuming and labor-intensive, which limits the treatment efficiency especia

299 eating short-cuts where network diffusion is intensive while annihilating underused connections.

300 cess to private datasets and computationally intensive workspace-based analysis require login/passwor