ライフサイエンスコーパス: interaction

1 95% CI 0.35-1.03; P = .062; P = .90 for the interaction).

2 directly activate basophils via cell-to-cell interaction.

3 mimic properly IgGs Fc domain/FcRn receptor interaction.

4 ial to act as competitive inhibitors of this interaction.

5 RNA in vitro, consistent with direct EF-RNA interaction.

6 up gamma band influences via cross-frequency interaction.

7 CUE) domain in SMARCAD1 mediate their direct interaction.

8 is for the conformational selectivity of the interaction.

9 rface in an optimal orientation by protein G interaction.

10 am1 protein by Ipl1 kinase destabilizes this interaction.

11 transformation, and novel E-cadherin-RalBP1 interaction.

12 icient strategy to identify the E3-substrate interaction.

13 a Rica to examine potential gene-environment interactions.

14 powerful tools for quantifying cell-material interactions.

15 ble to resolving many other receptor-pathway interactions.

16 orks is often improved by accounting for the interactions.

17 e to prevent their collapse and restore lost interactions.

18 e been widely used to study protein-membrane interactions.

19 anges of gene regulation and trans-homologue interactions.

20 as expected for predominantly electrostatic interactions.

21 asis may occur for traits involved in social interactions.

22 our decisions as we navigate complex social interactions.

23 by phosphorylation-dependent protein-protein interactions.

24 ide deeper insights into other host-pathogen interactions.

25 e immunomodulatory properties of Fc-FcgammaR interactions.

26 roups play important roles in compound-lipid interactions.

27 chemical characterization of receptor-ligand interactions.

28 th the additive (relative excess risk due to interaction, 5.06; 95% CI, 1.33-11.04) and multiplicativ

29 ity and population structure reflect complex interactions among a diverse set of processes that may v

30 planes that enhances the unscreened Coulomb interactions among charges.

31 he manner in which patterns of variation and interactions among demographic rates contribute to popul

32 r plumbing systems can result in undesirable interactions among plumbing components that undermine en

33 immunity requires the elucidation of complex interactions among sex hormones, sex chromosomes, and im

34 Where and how interaction analyses are implemented in the brain is unk

35 uantum chemical calculations and noncovalent interaction analysis.

36 Ks provides new insights into T. brucei-host interaction and reveals novel potential protein kinase d

37 hore of the key actin residues of Pfn1-actin interaction and therefore have the potential to act as c

38 direct stabilizing effect of ligand-protein interactions and an indirect destabilizing effect on int

39 hydrogen bonds in influencing intermolecular interactions and conformational preferences.

40 , the molecular determinants that govern the interactions and functions of these three proteins are s

41 Here we confirm PRC1-Br140 and PRC1-Fs(1)h interactions and identify their genomic binding sites.

42 results showing antagonistic galanin-opioid interactions and offers a new therapeutic target for the

43 light the contingent nature of predator-prey interactions and suggest that non-consumptive effects sh

44 ns often relies on the use of supramolecular interactions and the organization of functional elements

45 sstalk ( approximately 20% for one crosstalk interaction) and remain dynamically modular.

46 oGRID contains 1 072 173 genetic and protein interactions, and 38 559 post-translational modification

47 the lncRNA and promoter-spanning transcript interaction are based on a combination of structural and

48 Species and interactions are being lost at alarming rates and it is

49 ansduction complex, TMC1 and TMC2, and these interactions are disrupted by deafness-causing Cib2 muta

50 RNA-protein interactions are essential for proper gene expression re

51 review the evidence of whether mito-nuclear interactions are likely to pose a problem for MRT.

52 ate strategies that target receptor-receptor interactions are needed.

53 which predicts that deleterious mito-nuclear interactions are unlikely to be much more prevalent in i

54 Our finding uncovers Vangl2-Dvl interaction as a key bi-functional switch that underlies

55 n on the contribution of chytrids to trophic interactions, as well as co-evolutionary feedbacks of fu

56 Interaction assays identified FDH as a potential substra

57 arge, and in DNA binding and protein-protein interactions because key residues are truncated.

58 his selectivity is primarily mediated by the interaction between a peripheral element of the RNA that

59 upernova has been claimed as evidence for an interaction between a red-giant or a main-sequence compa

60 t ectopic expression of Gene 33 promotes the interaction between ATM and histone H2AX without trigger

61 Herein, by exploiting the electrostatic interaction between carbon networks and polymerized ioni

62 Previous studies showed that the interaction between CBFbeta-smooth muscle myosin heavy c

63 he ten-subunit Dam1/DASH complex bridges the interaction between kinetochores and microtubules, and s

64 he combined results indicate that the direct interaction between L1 and Reelin as well as the Reelin-

65 Striga-induced host damage results from the interaction between parasite virulence and genetically d

66 and expands a growing knowledge base on the interaction between positive-strand RNA [(+)RNA] viruses

67 This direct interaction between RNA polymerase and ribosomes may con

68 The coupled interaction between slow-wave oscillations and sleep spi

69 olecular "pi-pi" stacking and hydrophobicity interaction between SN-38, and a unique class of photoni

70 that arise from the multimodal nature of the interaction between the electromagnetic fields, such as

71 rly interesting and novel face-on halogen-pi interaction between the ligand's alkyl chloride and a gu

72 The physical interaction between the proteins was confirmed using flu

73 The interaction between the T cell antigen receptor (TCR) ex

74 assess the effects of iron and MMNs and the interaction between these factors.

75 deprotonated by alphaK145 to strengthen the interaction between this benzene ring and the agonist's

76 but not conformational, mutp53s enhance the interaction between TopBP1 and Treslin and promote DNA r

77 To evaluate the existence of an interaction between wine proteins and ethyl esters, the

78 Chen et al proposed that an interaction between Xist RNA and Lamin B receptor (LBR)

79 which are likely defined by intrinsic local interactions between amino acids close to each other in

80 ually all biological processes including the interactions between cells and biointerfaces, both natur

81 These results show that interactions between charged amino acid residues are imp

82 Ion-surface interactions between divalent Ca(2+) and Mg(2+) ions and

83 We also showed that the specific interactions between Gag and viral RNA are required for

84 Stop will facilitate investigations into the interactions between genes, circuits, and computation.

85 Interspecies meta-analysis suggested interactions between HNF4A and microbiota promote gene e

86 A factorial MANCOVA was used to detect interactions between hormonal plasma levels and ocular p

87 is amplified and transported upward through interactions between ions and neutrals or ambipolar diff

88 erlying several disease states involving the interactions between microbes, their metabolites, and th

89 Biology emerges from interactions between molecules, which are challenging to

90 Taking advantage of the interactions between negatively charged DNA and positive

91 study suggests a common pattern of molecular interactions between pneumococcal FnBPs and fibronectin.

92 Interactions between recruited APC and TC may occur as a

93 incorporate logical functions that describe interactions between regulators on downstream genes and

94 ar immunity is initiated by antigen-specific interactions between T lymphocytes and dendritic cells (

95 wed interest in the physics that governs the interactions between the angular momentum of photons and

96 No significant interactions between the aortic diameter and any of the

97 s and then by assessing the principal causal interactions between the primary, genetically based orga

98 en-presenting molecule CD1d is distinct from interactions between the TCR and major histocompatibilit

99 Investigations of putative functional interactions between these regions are complicated by mu

100 ivity of a UvrD dimer is promoted via direct interactions between UvrD subunits that affect the rotat

101 g methods for studying bacterial-endothelial interaction biomechanics.

102 With more than 56,000 candidate interactions, BioPlex 2.0 contains more than 29,000 prev

103 al guide to better assess biomaterial-tissue interactions both in vitro and in vivo.

104 ubiquitous nature of urea-aromatic stacking interactions by analyzing experimental structures of ure

105 This interaction can be disrupted by CXCR4 antagonists.

106 proof-of-principle study how this virus-host interaction can be employed to enhance efficacy of this

107 nary systems driven by specific non-covalent interactions can greatly expand the structural and funct

108 y depends on oligomerization and that client interactions can occur both with and without oligomer di

109 during bond formation, revealing how social interactions can recruit brain reward systems to drive c

110 ere is a striking enrichment of longer-range interactions connecting replication-dependent histone ge

111 -level accumulation, transport activity, and interaction contribute to PIN functional specificity.

112 suggest that airway smooth muscle/mast cell interactions contribute to asthma severity by transientl

113 This essentially unexploited attractive interaction could be more broadly utilized as a tool not

114 Since increasing the Vif-Pr55(Gag) interaction could potentially suppress virus proliferati

115 During S-phase, dynamic and stable interactions decreased considerably compared to G1-phase

116 Cation-pi interactions drive the self-assembly and cohesion of man

117 ritance and potentially complex gene product interactions during development, contributing to improve

118 traction of important information for social interaction (e.g., person identity).

119 performed to evaluate linear, quadratic and interaction effects between fermentation parameters.

120 We observed interaction effects between self-reported health status

121 ughput methods for screening protein-protein interactions enable the rapid characterization of engine

122 For most collision angles, the interaction energy is weak because only a few binding si

123 Such adhesive interactions enhanced levels of active Rac in adherent a

124 a factor necessary for dynactin-mitochondria interaction, enhancing our understanding of how mitochon

125 ll fractions, with intron, snoRNA and lncRNA interactions enriched in the nucleus.

126 materials, which can provide unique surface interactions for enabling novel forms of guided molecula

127 butions from phonon-phonon and electrostatic interactions for T > 110 K and larger contributions from

128 biological knowledge (i.e., protein-protein interactions) for biological network inference.

129 group (Q side chain) weakens the hydrophobic interaction generated by the six cyclohexyl side chains.

130 We probed these interactions genetically and identified second-site supp

131 InBioMap, or InWeb_IM) with severalfold more interactions (>500,000) and better functional biological

132 s have emerged for studying gene-environment interactions (GxEs) in large-scale studies of human popu

133 omain (e.g., E345K or E430G) enhancing Fc:Fc interactions, hexamer formation, and CDC after Ab binds

134 Our findings do not support the interaction hypothesis.

135 ging tools for the study of molecular-neural interactions important for the operation of the circadia

136 tested the evolutionary specificity of this interaction in a background in which the native A. thali

137 s with NLRC3 and can disrupt the NLRC3-STING interaction in the cytosol of human epithelial cells.

138 iant to disrupt a proposed Arg-His cation-pi interaction in the secondary coordination sphere of the

139 This unique in vivo nano-bio interaction in the sub-nanometre regime also slows down

140 , this study offers insights into host-virus interaction in tomato and provides valuable information

141 hat the Q311R mutation confers enhanced FcRn interaction in vitro, and Abs harboring either the Q311R

142 eal-time dynamic analysis and measurement of interactions in bio-molecular studies and cell-surface a

143 o alter RNA structures to affect RNA-protein interactions in cells.

144 Even if we assumed that interactions in fact did exist, we did not find evidence

145 A general framework for including biotic interactions in macroecological models would help bridge

146 diversity, viral metagenomics and virus-host interactions in natural ecosystems.

147 rior biological knowledge on gene-regulatory interactions in order to increase robustness and reprodu

148 The role of electrostatic interactions in the formation of lysozyme/LM pectin comp

149 portance of hydrogen bonding and hydrophobic interactions in the oligomerization of IAPP-derived pept

150 the detailed information about the molecular interactions in two filament states, we successfully pre

151 We measured binocular interactions in visual cortex of anesthetized amblyopic

152 Analogous interactions in vivo would permit lncRNAs to mediate the

153 r the study of dynamic regulation of protein interactions in vivo, there is a need for techniques tha

154 for Abeta(14-23) peptide shows that surface interactions induce conformational transitions of the mo

155 itical cytokine and we reveal its functional interaction interface with high-affinity ligands.

156 Protein-protein interactions involving intrinsically disordered proteins

157 acrophages, and the C. neoformans-macrophage interaction is modulated by exogenous lipids, providing

158 ain is essential for anchoring at parS, this interaction is not required for DNA condensation.

159 eficient ClBDPPV through anion-pi electronic interactions is strongly corroborated by the combined re

160 Interaction isotherms were derived from analytical signa

161 and EmGATAD2A/B proteins form a coiled-coil interaction known to be critical for the formation of Nu

162 the weak HB case, we have a lesser degree of interaction, leading to normal hydrogen bonds of type YH

163 This interaction may represent a therapeutic target in cancer

164 enless subcolonies that engage in more brood interactions may have had more resources available to co

165 ammalian membrane two-hybrid protein-protein interaction method, we identified eight novel interactio

166 his issue by focusing on the role of stromal interaction molecule 1 (STIM1), an endo/sarcoplasmic ret

167 receptor-interacting protein (RIP) homotypic interaction motifs (RHIM) play a key role in cell death

168 Remodelling of electrostatic interactions near the Cbeta H3 helix at the membrane-pro

169 esumed in G2-phase, indicating that specific interactions need to be dissolved for replication to pro

170 l, we provide a scored human protein-protein interaction network (InWeb_InBioMap, or InWeb_IM) with s

171 RF2, FAM111A, and RFC complex likely form an interaction network that influences the ability of poxvi

172 enhancers are more likely to form multi-TSS interaction networks and be associated with topologicall

173 erization of engineered binding proteins and interaction networks.

174 We will present herein an overview of the interactions occurring between the intestinal microbiota

175 We replicated the interaction of a variant in NOD2 with current smoking in

176 There was a significant interaction of BCPR with age.

177 RATIONALE: The interaction of circulating cells within the vascular wal

178 c modulatory effects of SRI-compounds on the interaction of cocaine with hDAT.

179 Reduced p62 levels impair interaction of p62 with Keap1, which further decreases N

180 We further examine the interaction of PorB with outer membrane-associated prote

181 In this new study, we investigated the interaction of protein phosphatase 1 (PP1) with the SR p

182 heterocyclic diamidine family disrupted the interaction of PU.1 with target gene promoters and led t

183 DNA, increase of DNA sensing by blocking the interaction of SIRPalpha with CD47 preferentially occurr

184 Interaction of the compounds with ABCG2 was investigated

185 mechanical model is developed to explain the interaction of the three components.

186 The interaction of these enzymes with the milk proteins and

187 within soils and sediments is the necessary interaction of two low-solubility phases-Cr(III) silicat

188 proteins and modulate the global folding and interactions of double helices with hundreds of basepair

189 ross population subgroups, analyses included interactions of ECT with age group, sex, race/ethnicity,

190 Thus, regulatory interactions of evolutionarily recent sRNAs can be acted

191 There were no significant interactions of genotypes with calcium supplementation.

192 rogress has been made toward controlling the interactions of longitudinal modes in lasers with a sing

193 east three-hybrid assays, we investigate the interactions of rProtein uL23 and its tail with Domain I

194 Interactions of starch with non-starch components, inclu

195 coiled-coil structure decreases the optimum interactions of the central part of Tm with the C-termin

196 argeted by many pathogens, promotes vascular interactions of the Lyme disease spirochete Borrelia bur

197 Strong-field laser-matter interactions often lead to exotic chemical reactions.

198 s and allergic sensitization had significant interactions on both the additive (relative excess risk

199 to study the consequences of plant-pathogen interactions on fertility and the evolution of intercell

200 families can be used to identify drug-target interactions, opening a new research direction in target

201 We studied the regulatory interactions operating within and across organs througho

202 e predictive effects, with no evidence of an interaction (p = 0.329 and p = 0.291 for CKD and CVD, re

203 We found a significant interaction (p=0.051) between type of fractionation and

204 ations, interfacial curvature, electrostatic interactions, partition coefficients and miscibility of

205 and define PKC as an important beta-catenin interaction partner and signaling opponent of other PKC

206 nteraction method, we identified eight novel interaction partners of EGFR, of which half strongly int

207 Hence, identification of interaction partners that bind to mutated EGFR can help

208 marize the biochemical activities, host cell interaction partners, and physiological functions of SPI

209 transport of the protein independent of its interaction partners.

210 for rigorous testing of the role that biotic interactions play in determining species ranges.

211 Protein-protein interactions (PPIs) of these subunits play pivotal roles

212 Disordered protein-protein interactions (PPIs), those involving a folded protein an

213 This unique interaction provides a structural basis for grazoprevir'

214 responses to individual stimuli and to their interaction regardless of attentional task, although a s

215 programmed death-1 (PD-1) and PD-L1 and B7-1 interactions, reinvigorating anticancer immunity.

216 es has uncovered effects of gene-environment interactions relevant to drug response and immunity, and

217 infectivity although a significance of their interaction remained enigmatic.

218 s attenuation is mediated only through PR-ER interaction remains unknown.

219 nd injury disrupt the epithelial-mesenchymal interactions required for normal development.

220 distinct co-occurrence networks of bacterial interactions revealed both common and unique features in

221 , RNA alignment, RNA annotation, RNA-protein interaction, ribosome profiling, RNA-seq analysis and RN

222 Ca(2+)-ATPase isoform 8 (ACA8) and that this interaction stimulates ACA8 activity.

223 ants, but that their relative importance and interaction strength varied with the spatial extent of t

224 e found they can point to larger networks of interactions, such as with proteins that serve as hubs f

225 IDREAM models contain many fewer interactions than PROM and yet produce significantly mor

226 late actinides participate in more covalent interactions than the earlier actinides, yet the origin

227 ng a C2B surface implicated in SNARE complex interaction that is required for rapid synchronization a

228 al models on networks, dynamics are based on interactions that exclusively involve properties of a no

229 ndirect destabilizing effect on intraprotein interactions that is induced by the ligand.

230 lexibility and the transient nature of their interactions, these limitations had precluded structural

231 small molecules inhibit the protein-protein interactions through covalent modification of cysteine r

232 ater availability to impact plant-pollinator interactions through pollinator responses to differences

233 riginal antigenic sin and negative antigenic interaction, to support development of improved influenz

234 ed by assessing human neutrophil-endothelial interactions under flow: PD1n-3 DPA and RvD5n-3 DPA redu

235 ther mechanisms also affect coral-macroalgal interactions under OA, and OA further suppresses the res

236 gists use the term 'precision' to facilitate interactions using a common language.

237 in supramolecular complexes, and regulatory interactions) using CellDesigner software.

238 inoculation of P. flocculosa, the tripartite interaction was monitored over time and samples collecte

239 teresting substrate-solvent hydrogen-bonding interaction was observed.

240 To investigate such protein interactions, we establish a ribosome affinity purificat

241 No interactions were observed between lead or bone turnover

242 chemicals released from spores, germination interactions were quantified for four species.

243 Dipole-dipole interactions, which govern phenomena such as cooperative

244 ication of Tn-Seq is for identifying genetic interactions, which involves comparing Tn mutant librari

245 viously unexplored Wnt-Frizzled and Wnt-SFRP interactions, which, in turn, may reveal further Wnt sig

246 rption of the FtSs was driven by hydrophobic interactions, while the FtSaBs behave more like cations

247 Shifts in trophic interactions will be especially important when affecting

248 kines in various biological matrices and its interaction with a natural receptor molecule has tremend

249 This direct interaction with actin suggests a new role of SPARC duri

250 ranoanthocyanins led to an increase in their interaction with aPRPs.

251 cts mitochondrial ATP production through its interaction with ATP5alpha, whereas this relationship wa

252 ition is further supported by its functional interaction with BasA (sphingolipid biosynthesis) and St

253 W1L4L8 that is known to be important in the interaction with centrin.

254 C-terminal domains of TTP are involved in an interaction with CNOT9.

255 Predefined subgroup analyses found no interaction with ejection fraction less than 30%, type o

256 over, mutation of this residue blocks PKD2's interaction with Focal Adhesion Kinase (FAK).

257 -GTPase Cdc42p promotes yeast fusion through interaction with Fus2p, a pheromone-induced amphiphysin-

258 at conformational changes in KCNQ1 alter its interaction with KCNE1.

259 el mitochondrial effectors in H. pylori-host interaction with links on gastric pathogenesis.

260 We propose that the cis interaction with P2Y2R provides allosteric resistance to

261 CI is directed to PDs through its interaction with P3N-PIPO.

262 P motif attenuate or abolish human MutLalpha interaction with PCNA, as well as PCNA-dependent activat

263 Rather, mutations that disrupted the pTRS1 interaction with PKR ablated the ability of pTRS1 to ant

264 quired for this effect, independently of the interaction with PTPdelta, but IL1RAPL1 mediates the act

265 at is partially masked by its intramolecular interaction with R9.

266 icular and sperm function in adult males via interaction with relaxin/insulin-like family peptide rec

267 Rca hexamer ring and analyzed its functional interaction with Rubisco.

268 mation-associated H443P mutant is altered in interaction with SUG1 and ubiquitinated proteins, trigge

269 llular matrix can direct and regulate vaspin interaction with target proteases or other proteins and

270 A paradigm for pneumococci is their interaction with the adhesive glycoprotein fibronectin,

271 understanding the life cycle of HCV and its interaction with the host cells.

272 e is a rearrangement in the eag domain-CNBHD interaction with the kinetics, voltage-dependence, and A

273 spatial orientation of tryptic peptides upon interaction with the negatively charged surface function

274 binding mechanisms and affinities for their interaction with the PRR of Itch.

275 YAP O-GlcNAcylation disrupts its interaction with upstream kinase LATS1, prevents its pho

276 l targeting depends on co-expression of, and interaction with, LMBD1.

277 transitions of the monomer, which facilitate interactions with another monomer that undergoes conform

278 lants, including crops, engage in beneficial interactions with arbuscular mycorrhizal fungi.

279 ctivity of each of these proteins depends on interactions with both ribosomal subunits, some portion

280 Le(X)) and display markedly greater adhesive interactions with E-selectin than do circulating lymphoc

281 of exogenous Lactobacillus plantarum and its interactions with intestinal bacteria in mice undergoing

282 mechanisms of RNA folding and unfolding, its interactions with ligands, and its functions.

283 imes, known as coherence times or T2, due to interactions with nuclear spins in the local environment

284 ng ATGL lipid droplet translocation or ABHD5 interactions with perilipin proteins and ABHD5 ligands,

285 yntheses using building blocks optimized for interactions with subtype-specific residues in the PPARd

286 ectrocatalytic behavior, mass transport, and interactions with surfaces.

287 he ligand to misalign the QA and form weaker interactions with the aromatic groups.

288 hermore, sodium enhanced [(3)H]rauwolscine's interactions with the BiOctR, but not at a vertebrate al

289 imal face of the TCR, a region implicated in interactions with the CD3 co-receptor, suggests a possib

290 y in the Vbeta8.1 segment mediated essential interactions with the GAP5040-48 peptide.

291 ore, G40 can also establish hydrogen bonding interactions with the nonbridging oxygen of the scissile

292 , we have a localized particle with nonlocal interactions with the other slit.

293 ulate alternative splicing decisions through interactions with the splicing machinery.

294 nd in some cases sequence-specific molecular interactions with the surface of carbon nanotubes that r

295 et morphology to enzyme activity (host-guest interactions with uncaging and molecular cleavage).

296 ciency, strength, and stability of bacterial interactions with vascular surfaces.

297 urements reveal rapid changes in protein-RNA interactions within 1 min following stress imposition.

298 aging enables to study dynamic tumour-stroma interactions within primary and metastatic sites, includ

299 Thus, feedback interactions within the ERK pathway can regulate cell pr

300 standing and controlling polycation-membrane interactions, yet such information is surprisingly diffi