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2 ome, we uncovered its specific and prevalent interaction with a large subset of primary microRNAs (pr
4 kines in various biological matrices and its interaction with a natural receptor molecule has tremend
5 lack of interface specificity indicates that interaction with a particular ACh binding site is not th
7 he translational machinery is mediated by an interaction with a specific ribosomal protein, RACK1, an
16 helial junctions are partially modulated via interaction with Ajuba, an actin binding and scaffolding
18 Here, we show that ERG, through its physical interaction with androgen receptor, induces AR aggregati
19 transitions of the monomer, which facilitate interactions with another monomer that undergoes conform
21 Nef dimerization interface also reduced Nef interactions with AP-2 and CD4 and restored CD4 expressi
23 ect events documented in vitro following IgG interaction with AQP4: AQP4 internalization, attenuated
27 r Drp1 in fed cells and in autophagy through interaction with Atg14L and other SNAREs in starved cell
28 cts mitochondrial ATP production through its interaction with ATP5alpha, whereas this relationship wa
31 ition is further supported by its functional interaction with BasA (sphingolipid biosynthesis) and St
32 Correspondingly, CD177 ligation enhanced its interaction with beta2 integrins, as revealed by fluores
33 of time during their biogenesis and rely on interactions with binding partners to support proper fol
34 nd G3BP protein families, and only a lack of interaction with both protein families strongly affects
35 on HCA1, causing direct interference of HCA1 interaction with both the N-glycan and peptide-moiety of
36 to DNA double-strand breaks through bivalent interactions with both histone and DNA components of the
37 ctivity of each of these proteins depends on interactions with both ribosomal subunits, some portion
39 , CRIP1a can compete with beta-arrestins for interaction with C-terminal CB1R domains that could affe
40 lta1 averts its cell-surface expression, its interaction with CaValpha1, and modulation of CaV1.2 cur
42 ular motifs on xylan conformation and on the interaction with cellulose surfaces in Norway spruce (Pi
43 am of MeCP2 that influences neurogenesis via interactions with central molecular hubs linked to autis
45 ed surgery and to explore the effect surgery interaction with chemotherapy or radiation therapy on su
51 unknown to what degree diverse TCR-mediated interactions with cognate self-antigens are required for
53 c control of this process, including genetic interactions with crop quality parameters, is poorly und
56 Thr(187)-Pro motif in p27 and reduces p27's interaction with cyclin A- or cyclin E-CDK2, leading to
57 pacting embryonic gene expression, and their interactions with developmental programs, remain largely
59 mutants on its transcriptional activity and interactions with DNA, transcriptional cofactors and chr
61 Le(X)) and display markedly greater adhesive interactions with E-selectin than do circulating lymphoc
63 associates with histone partially through an interaction with EIN2 nuclear-associated protein1 (ENAP1
64 binding regions are more accessible upon the interaction with EIN2, and more EIN3 proteins bind to th
68 olysaccharide digestion, including microbial interactions with endogenous host glycans and the import
71 n, ethylenediamine) promotes a high-affinity interaction with exquisite selectivity for this sequence
74 horylation promotes RIPK1 activation and its interaction with FADD to mediate RIPK1-dependent apoptos
77 rapment by carbon shells and strong chemical interaction with Fe3 O4 cores, this unique architecture
78 gesting that WRN recruitment and cooperative interaction with FEN1 during lagging-strand synthesis ma
79 ce and binding studies that the pneumococcal interaction with fibronectin is a non-human specific tra
83 bf4 is enriched at early origins through its interaction with forkhead transcription factors Fkh1 and
84 -GTPase Cdc42p promotes yeast fusion through interaction with Fus2p, a pheromone-induced amphiphysin-
85 ut mitral cells (MCs) appears to result from interactions with GABAergic granule cells (GCs), yet the
86 achment of individual nanoparticles, and the interaction with gas molecules plays a critical role, wh
88 at are still not fully understood such as QD interactions with gold and other metal nanoparticles alo
89 AV1 scaffolding domain, indicating that CAV1 interaction with GRK2 is inversely regulated by endothel
92 ortance of the Rev-erbbeta HRM in regulating interactions with heme and NCoR1 and advance our underst
93 n enhancing torsadogenic effects: oestradiol interaction with hERG mutations in the pore loop contain
95 iety of GRL-09510 forms strong hydrogen-bond-interactions with HIV-1 protease (PR) active-site amino
96 ediating uptake by immune cells, or blocking interaction with host cell receptors, making them a desi
97 he F-driven formation of VLPs occurs through interactions with host cell machinery, the cytoplasmic t
98 ability of the AIPL1 variants to mediate an interaction with HSP90 and modulate the rod cGMP PDE6 st
101 ink between histamine-releasing factor (HRF) interactions with IgE and food allergy in a murine model
102 y to characterize the truncated NEMO protein interactions with IKK-alpha, IKK-beta, TNF receptor-asso
104 y driven insight into the rise of ecological interactions, with implications for microbiome research
105 ape recognition can also be achieved by cell interaction with imprints that can be made into polymer
106 wn that MSC tumour residence and their close interactions with inflammatory factors are important fac
107 the regulation of insect development via the interaction with insect hormones, such as ecdysone and j
109 of exogenous Lactobacillus plantarum and its interactions with intestinal bacteria in mice undergoing
117 nistic knowledge of how it functions and its interactions with lipids are unknown or limited due to i
121 , our structural understanding of the MBS CC interaction with LZ PKG-1alpha has remained limited.
122 ontrol membrane curvature and to modify HA's interaction with M1 protein, while the stunting of fusio
123 annose Man9GlcNAc2 oligosaccharide exhibited interaction with Manalpha1-2Man on two different termini
124 toplasmic amino-terminus of iRhom2 alter its interaction with mature TACE, thereby licensing its prot
127 n membranes: a precise understanding of RAS' interaction with membranes is essential to understand RA
128 of the beta2-adrenoceptor ligands and their interactions with membranes, we have investigated the lo
130 e networks in circulating human cells, their interactions with metabolites, and their genetic control
131 hues in nature are not fully understood, but interactions with metal ions and phenolic compounds are
134 tanding of the physics of surface structures interactions with microscale heat and mass transfer even
136 ed by pharmacologic blockade of FcRn-albumin interactions with monoclonal antibodies or peptide mimet
138 ain the specialized domains formed by axonal interaction with myelinating Schwann cells, such as clus
141 he LIM domains of Rga1 are necessary for its interaction with Nba1, and loss of this interaction resu
143 ipathic conformation, which allows increased interaction with negatively charged bacterial membranes.
144 cytes to (re)generate myelin and that failed interactions with neighboring cells or factors in the di
147 ght to be strongly structured by competitive interactions, with niche partitioning of food resources
151 s maintained in a reduced state by substrate-interaction with NRX1, a process necessary for its H2O2-
152 imes, known as coherence times or T2, due to interactions with nuclear spins in the local environment
154 rk and default mode network strengthen their interaction with one another during episodic retrieval.
155 how RNA can remain soluble and available for interaction with other molecules in the cell despite the
156 ccoides subpopulations depend on synergistic interaction with other organohalide-respiring population
158 ultiple subunits, but how this regulates CPC interactions with other mitotic proteins remains unclear
159 ifferent sub-regions of the rVLPFC and their interactions with other motor-related brain regions.
160 interactions with proteases while preserving interactions with other proteins, such as target recepto
161 ight), increased illness (usually diarrhea), interactions with other trace elements such as copper an
162 ellular localization and result in decreased interactions with p210-selective interaction partners.
165 n, Mdm2 deletion differed from blocking Mdm2 interaction with p53 family members, as Nutlin-3 induced
166 associated polymorphism does not abolish the interaction with p73alpha, indicating that oncosuppresso
167 infecting tomato as a system to dissect host interactions with pathogenic ncRNAs, using comprehensive
168 ponderance appear to have evolved from human interactions with pathogens in the microbial world.
169 enty hours of observation of nursing staff's interactions with patients and families was conducted, u
170 groups were asked to describe their typical interactions with patients, family members, doctors, and
171 P motif attenuate or abolish human MutLalpha interaction with PCNA, as well as PCNA-dependent activat
173 ng ATGL lipid droplet translocation or ABHD5 interactions with perilipin proteins and ABHD5 ligands,
174 o alter apical membrane identity through its interactions with phosphatidylinositol 3-kinase (PI3K) a
176 of the N-terminal amine further limited its interactions with phospholipid head-groups to facilitate
177 abled the design of mutants that disrupt Tau interactions with phospholipids without interfering with
180 Rather, mutations that disrupted the pTRS1 interaction with PKR ablated the ability of pTRS1 to ant
182 ion has the potential to selectively perturb interactions with proteases while preserving interaction
183 resistant layer, which prevents nonspecific interactions with proteins and a layer containing the Ep
184 tric-based evidence to show that metallodrug interactions with proteins are considerably more complex
185 w similar overall rules of self-assembly and interactions with proteins, but that differences in the
186 quired for this effect, independently of the interaction with PTPdelta, but IL1RAPL1 mediates the act
187 structural and functional aspects of ligand interactions with purified P-gp and other ATP-binding ca
189 and binding with alpha-helix formation upon interaction with RCD1, whereas peptides from ANAC013 and
191 proteins (GlnB and GlnK), which orchestrate interactions with regulators of gene expression, transpo
192 shape deformations on filament stability and interactions with regulatory proteins, and analysis of s
193 icular and sperm function in adult males via interaction with relaxin/insulin-like family peptide rec
194 al role of the inflammatory response and its interactions with resident airway cells is critical to a
196 ons in the RPA32 subunit of RPA that abolish interaction with RFWD3 also inhibit ICL repair, demonstr
197 of macronutrient deficiencies and symbiotic interactions with rhizobia and mycorrhiza were investiga
201 verall shape complementarity and hydrophobic interactions with S372 and M368 on KCa3.1 and M72 on CaM
202 protein Lpd regulates actin dynamics through interactions with Scar/WAVE and Ena/VASP proteins to pro
208 concentration of receptor available for the interaction with specific targets, and thus has an impac
210 n altered RNA structure that facilitates the interaction with SRSF3, an SR protein family member that
211 ngle-stranded DNA (ssDNA) is notable for its interactions with ssDNA binding proteins (SSBs) during f
212 yntheses using building blocks optimized for interactions with subtype-specific residues in the PPARd
213 mation-associated H443P mutant is altered in interaction with SUG1 and ubiquitinated proteins, trigge
214 ant p53 interacts with Rac1 and inhibits its interaction with SUMO-specific protease 1 (SENP1), which
216 tating properties of Kv2.1, specifically its interaction with syntaxin 1A, could lead to neuroprotect
217 data support a specific mode of TIA-1 RRM23 interaction with target oligonucleotides consistent with
218 llular matrix can direct and regulate vaspin interaction with target proteases or other proteins and
219 As (miRNAs) regulate gene expression through interactions with target sites within mRNAs, leading to
222 dinates in a hitherto unreported monodentate interaction with the active site Fe(2+) ion, while the b
225 ysis of tissue distribution reveals that the interaction with the antibody reduces the concentration
226 s, and computational docking to analyze GRK5 interaction with the beta2-adrenergic receptor (beta2AR)
227 s in ARTEMIS-deficient patients impaired the interaction with the C terminus and also affected protei
229 elope glycoprotein in order to withstand the interaction with the cellular receptor during virus form
230 that confinement at the nanoscale and direct interaction with the charged interfaces produce anomalou
231 ty and cytokine secretion upon high-affinity interaction with the cognate CTLR keratinocyte-associate
233 receptors 1 and 2 with significantly reduced interaction with the decoy TRAIL receptors 3 and 4.
234 hat this effect may be because of mechanical interaction with the dilated main pulmonary artery (MPA)
235 on the really interesting new gene (RING)-H2 interaction with the E2 enzyme UbcH5b in order to ligate
237 n in the Gal1 co-activator that disrupts the interaction with the Gal80 inhibitor specifically and co
238 in particular, the drug release kinetics and interaction with the gastrointestinal (GI) membrane.
241 e to this period of brain maturation and its interaction with the hormonal changes of pregnancy and p
243 amino acids in RRM1 likely to be involved in interaction with the i-motif DNA, and His24 and Arg26 we
244 heme binding protein (PhuS) is required for interaction with the iron-regulated heme oxygenase (HemO
245 rylation of ATR on S435 which promoted ATR's interaction with the key NER factor xeroderma pigmentosu
246 e is a rearrangement in the eag domain-CNBHD interaction with the kinetics, voltage-dependence, and A
248 coid (GC) downregulation of wound healing by interaction with the membrane bound GC receptor, followe
249 , additional epigenetic changes triggered by interaction with the microenvironment modulate cancer ce
250 regulation of mitochondrial dynamics through interaction with the mitochondrial fission factor Drp1 i
251 etabolism is needed to better understand its interaction with the motor symptoms of the disease.
252 Aha1-Hsp90 complex but prevents the specific interaction with the N-terminal domain of Hsp90 required
253 spatial orientation of tryptic peptides upon interaction with the negatively charged surface function
255 ng to Rev-erbbeta indirectly facilitates its interaction with the nuclear receptor co-repressor (NCoR
260 we have identified a key difference in their interaction with the ribosome, which correlates with the
261 by modulating YB-1 nuclear localization and interaction with the splicing factor U2AF65, which promo
262 etween 4 K and 340 K and the nature of their interaction with the surrounding inorganic cage using a
263 anslocated from the ER to the nucleus, where interaction with the WRKY29 transcription factor occurs.
265 mational change that relieves autoinhibitory interactions with the ATPase motor, which selectively ac
266 hermore, sodium enhanced [(3)H]rauwolscine's interactions with the BiOctR, but not at a vertebrate al
267 pling and abundance of CaV2.1 through direct interactions with the CaV2.1 alpha1 subunit C-terminus a
268 imal face of the TCR, a region implicated in interactions with the CD3 co-receptor, suggests a possib
269 dered, yet utilizes transient intramolecular interactions with the DNA-recognition helix of the ETS d
271 rgeted localization of proteins required for interactions with the extracellular matrix and for prote
275 molecules demonstrates that the non-covalent interactions with the host hardly affect the dihedral an
276 n CENP-N confers binding specificity through interactions with the L1 loop of CENP-A, stabilized by e
277 breast cancer patients, depend on tumor cell interactions with the mineralized bone extracellular mat
278 ore, G40 can also establish hydrogen bonding interactions with the nonbridging oxygen of the scissile
281 ent interface are difficult to compensate by interactions with the protein or surrounding water molec
283 erent AAV serotypes have evolved distinctive interactions with the same receptor.IMPORTANCE Over the
285 we observe the translocon positioned through interactions with the SR in the vicinity of the ribosome
286 nd in some cases sequence-specific molecular interactions with the surface of carbon nanotubes that r
289 alled corona which may strongly modify their interaction with tissues and cells relative to the bare
291 c cochlin produces a qualitatively different interaction with TREK-1 compared to monomeric cochlin.
292 stalk movement and to understand its dynamic interactions with tRNA and other structural elements of
293 ciated with the replication fork through its interactions with two proteins, Proliferating Cell Nucle
294 et morphology to enzyme activity (host-guest interactions with uncaging and molecular cleavage).
298 ificantly disrupts its nuclear localization, interaction with VDR, intra-nuclear trafficking, and bin
299 his suggests that CTR-truncation disrupts an interaction with VLDLR (very low-density lipoprotein rec
300 ion of WASp at Y102 negatively regulates its interaction with Wiskott-Aldrich interacting protein and
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